Bupropion, an atypical antidepressant, induces endoplasmic reticulum stress and caspase-dependent cytotoxicity in SH-SY5Y cells

Toxicology

Volumn 285, Issue 1-2, 2011, Pages 1-7

  Jang, Eun Hee ^a,b   Park, Chang Shin ^a   Kang, Ju Hee ^a,b  

^a Inha University School of Medicine   (South Korea)

^b Inha University Hospital   (South Korea)

Author keywords

Bupropion; Caspase; Cytotoxicity; Endoplasmic reticulum stress; JNK; SH SY5Y

Indexed keywords

AMFEBUTAMONE; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR 4; DEATH RECEPTOR 5; INITIATION FACTOR 2ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; NEUROTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SMOKING CESSATION;

ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; APOPTOSIS; BUPROPION; CASPASE 3; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NEUROBLASTOMA; PHOSPHORYLATION; RNA, MESSENGER; TIME FACTORS;

EUKARYOTA;

EID: 79956200408     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.02.006     Document Type: Article

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