메뉴 건너뛰기




Volumn 86, Issue 5, 2003, Pages 1247-1259

Hydrogen peroxide induces-loss of dopamine transporter activity: A calcium-dependent oxidative mechanism

Author keywords

Calcium; Dopamine transporter; Hydrogen peroxide; Hydroxyl radicals; PC12; Reactive oxygen species

Indexed keywords

CALCIUM; CATALASE; CONCANAVALIN A; CUMENE; DITHIODIPYRIDINE; DOPAMINE TRANSPORTER; HYDROGEN PEROXIDE; OXIDIZING AGENT; THAPSIGARGIN; UNCLASSIFIED DRUG;

EID: 0041430627     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01936.x     Document Type: Article
Times cited : (32)

References (64)
  • 2
    • 15144343374 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF)-induced generation of hydrogen peroxide: Role in EGF receptor-mediated tyrosine phosphorylation
    • Bae S. Y., Kang S. W., Seo M. S., Banies I. C., Tekle E., Chock P. B. and Rhee S. G. (1997) Epidermal growth factor (EGF)-induced generation of hydrogen peroxide: role in EGF receptor-mediated tyrosine phosphorylation. J. Biol. Chem. 272, 217-221.
    • (1997) J. Biol. Chem. , vol.272 , pp. 217-221
    • Bae, S.Y.1    Kang, S.W.2    Seo, M.S.3    Banies, I.C.4    Tekle, E.5    Chock, P.B.6    Rhee, S.G.7
  • 3
    • 0020625894 scopus 로고
    • Flow cytometric studies of oxidative product formation by neutrophils: A graded response to membrane stimulation
    • Bass D. A., J. W. Parce L. R., Dechatelet P., Szejda M. C., Seeds and Thomas M. (1983) Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J. Immunol. 130, 1910-1917.
    • (1983) J. Immunol. , vol.130 , pp. 1910-1917
    • Bass, D.A.1    Parce, L.R.J.W.2    Dechatelet, P.3    Szejda, M.C.4    Seeds5    Thomas, M.6
  • 4
    • 0032535497 scopus 로고    scopus 로고
    • Protein kinase A activity may kinetically upregulate the striatal transporter for dopamine
    • Batchelor M. and Schenk J. O. (1998) Protein kinase A activity may kinetically upregulate the striatal transporter for dopamine. J. Neurosci. 18, 10304-10309.
    • (1998) J. Neurosci. , vol.18 , pp. 10304-10309
    • Batchelor, M.1    Schenk, J.O.2
  • 5
    • 0028028155 scopus 로고
    • Radiation inactivation studies of the dopamine reuptake transporter protein
    • Berger S. P., Farrell K., Conant D., Kempner E. S. and Paul S. M. (1994) Radiation inactivation studies of the dopamine reuptake transporter protein. Mol. Pharmacol. 46, 726-731.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 726-731
    • Berger, S.P.1    Farrell, K.2    Conant, D.3    Kempner, E.S.4    Paul, S.M.5
  • 6
    • 0030056223 scopus 로고    scopus 로고
    • Modification of dopamine transporter function: Effect of reactive oxygen species and dopamine
    • Berman S. B., Zigmond M. J. and Hastings T. G. (1996) Modification of dopamine transporter function: effect of reactive oxygen species and dopamine. J. Neurochem. 67, 593-600.
    • (1996) J. Neurochem. , vol.67 , pp. 593-600
    • Berman, S.B.1    Zigmond, M.J.2    Hastings, T.G.3
  • 7
    • 0030878756 scopus 로고    scopus 로고
    • Reactive oxygen species and calcium homeostasis in cultured human intestinal smooth muscle cells
    • Bielefeldt K., Whiteis C. A., Sharma R. V., Abboud F. M. and Conklin J. L. (1997) Reactive oxygen species and calcium homeostasis in cultured human intestinal smooth muscle cells. Am. J. Physiol. 272, G1439-G1450.
    • (1997) Am. J. Physiol. , vol.272
    • Bielefeldt, K.1    Whiteis, C.A.2    Sharma, R.V.3    Abboud, F.M.4    Conklin, J.L.5
  • 8
    • 0032007849 scopus 로고    scopus 로고
    • Binding of iron and inhibition of iron-dependent oxidative cell injury by the 'calcium chelator' 1,2-bis (2-aminophenoxy) ethane N,N,N′,N′-tetraacetic acid (BAPTA)
    • Britigan B. E., Rasmussen G. T. and Cox C. D. (1998) Binding of iron and inhibition of iron-dependent oxidative cell injury by the 'calcium chelator' 1,2-bis (2-aminophenoxy) ethane N,N,N′,N′-tetraacetic acid (BAPTA). Biochem. Pharmacol. 55, 287-295.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 287-295
    • Britigan, B.E.1    Rasmussen, G.T.2    Cox, C.D.3
  • 10
    • 0037104715 scopus 로고    scopus 로고
    • The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter
    • Cameiro A. M., Ingram S. L., Beaulieu J. M., Sweeney A., Amara S. G., Thomas S. M., Caron M. G. and Torres G. E. (2002) The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter. J. Neurosci. 22, 7045-7054.
    • (2002) J. Neurosci. , vol.22 , pp. 7045-7054
    • Cameiro, A.M.1    Ingram, S.L.2    Beaulieu, J.M.3    Sweeney, A.4    Amara, S.G.5    Thomas, S.M.6    Caron, M.G.7    Torres, G.E.8
  • 12
    • 0033981373 scopus 로고    scopus 로고
    • Permeation and gating residues in serotonin transporter
    • Chen J. G. and Rudnick G. (2000) Permeation and gating residues in serotonin transporter. Proc. Natl Acad. Sci. U S A. 97, 1044-1049.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 1044-1049
    • Chen, J.G.1    Rudnick, G.2
  • 13
    • 0034695678 scopus 로고    scopus 로고
    • Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter
    • Chen N., Ferrer J. V., Javitch J. A. and Justice J. B. Jr (2000) Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter. J. Biol. Chem. 275, 1608-1614.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1608-1614
    • Chen, N.1    Ferrer, J.V.2    Javitch, J.A.3    Justice J.B., Jr.4
  • 14
    • 0027515194 scopus 로고
    • Multiple mechanisms for desensitization of A2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells
    • Chem Y., Lai H.-L., Fong J.-C. and Liang Y. (1993) Multiple mechanisms for desensitization of A2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells. Mol. Pharmacol. 44, 950-958.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 950-958
    • Chem, Y.1    Lai, H.-L.2    Fong, J.-C.3    Liang, Y.4
  • 17
    • 0033544844 scopus 로고    scopus 로고
    • Regulated trafficking of the human dopamine transporter: Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
    • Daniels G. M. and Amara S. G. (1999) Regulated trafficking of the human dopamine transporter: clathrin-mediated internalization and lysosomal degradation in response to phorbol esters. J. Biol. Chem. 274, 35794-35801.
    • (1999) J. Biol. Chem. , vol.274 , pp. 35794-35801
    • Daniels, G.M.1    Amara, S.G.2
  • 18
    • 0030001780 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant therapy in Parkinson's disease
    • Ebadi M., Srinivasan S. K. and Baxi M. D. (1996) Oxidative stress and antioxidant therapy in Parkinson's disease. Prog. Neurobiol. 48, 1-19.
    • (1996) Prog. Neurobiol. , vol.48 , pp. 1-19
    • Ebadi, M.1    Srinivasan, S.K.2    Baxi, M.D.3
  • 19
    • 0032482945 scopus 로고    scopus 로고
    • Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter
    • Ferrer J. V. and Javitch J. A. (1998) Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter. Proc. Natl Acad. Sci. USA 95, 9238-9243.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9238-9243
    • Ferrer, J.V.1    Javitch, J.A.2
  • 20
    • 0032125186 scopus 로고    scopus 로고
    • Role of dopamine transporter in methamphetamine-induced neurotoxicity: Evidence from mice lacking the transporter
    • Fumagalli F., Gainetdinov R. R., Valenzano K. J. and Caron M. G. (1998) Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter. J. Neurosci. 18, 4861-4869.
    • (1998) J. Neurosci. , vol.18 , pp. 4861-4869
    • Fumagalli, F.1    Gainetdinov, R.R.2    Valenzano, K.J.3    Caron, M.G.4
  • 21
    • 0030877835 scopus 로고    scopus 로고
    • Dopamine transporter is required for in vivo MPTP neurotoxicity: Evidence from mice lacking the transporter
    • Gainetdinov R. R., Fumagalli F., Jones S. R. and Caron M. G. (1997) Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. J. Neurochem. 69, 1322-1325.
    • (1997) J. Neurochem. , vol.69 , pp. 1322-1325
    • Gainetdinov, R.R.1    Fumagalli, F.2    Jones, S.R.3    Caron, M.G.4
  • 22
    • 0027535205 scopus 로고
    • Molecular characterization of the dopamine transporter
    • Giros B. and Caron M. G. (1993) Molecular characterization of the dopamine transporter. Trends Pharmacol. Sci. 14, 43-49.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 43-49
    • Giros, B.1    Caron, M.G.2
  • 23
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B., Jaber M., Jones S. R., Wightman R. M. and Caron M. G. (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379, 606-612.
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 24
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 25
    • 0035964192 scopus 로고    scopus 로고
    • Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment
    • Hastrup H., Karlin A. and Javitch J. A. (2001) Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment. Proc. Natl Acad. Sci. USA 98, 10055-10060.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10055-10060
    • Hastrup, H.1    Karlin, A.2    Javitch, J.A.3
  • 27
    • 0033534690 scopus 로고    scopus 로고
    • Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulin-secreting cell line
    • Herson P. S., Lee K., Pinnock R. D., Hughes J. and Ashford M. L. J. (1999) Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulin-secreting cell line. J. Biol. Chem. 274, 833-841.
    • (1999) J. Biol. Chem. , vol.274 , pp. 833-841
    • Herson, P.S.1    Lee, K.2    Pinnock, R.D.3    Hughes, J.4    Ashford, M.L.J.5
  • 28
    • 0032974483 scopus 로고    scopus 로고
    • Modulation of dopamine transporter activity by nicotinic acetylcholine receptors and membrane depolarization in rat pheochromocytoma PC12 cells
    • Huang C.-L., Chen H.-C., Huang N.-K., Yang D.-M., Kao L.-S., Chen J.-C., Lai H.-L. and Chem Y. (1999) Modulation of dopamine transporter activity by nicotinic acetylcholine receptors and membrane depolarization in rat pheochromocytoma PC12 cells. J. Neurochem. 72, 2437-2444.
    • (1999) J. Neurochem. , vol.72 , pp. 2437-2444
    • Huang, C.-L.1    Chen, H.-C.2    Huang, N.-K.3    Yang, D.-M.4    Kao, L.-S.5    Chen, J.-C.6    Lai, H.-L.7    Chem, Y.8
  • 29
    • 0343580433 scopus 로고    scopus 로고
    • Amphetamine induces hydroxyl radical formation in the striatum of rats
    • Huang N.-K., Wan F. J., Tseng C. J. and Tung C. S. (1997) Amphetamine induces hydroxyl radical formation in the striatum of rats. Life Sci. 61, 2219-2229.
    • (1997) Life Sci. , vol.61 , pp. 2219-2229
    • Huang, N.-K.1    Wan, F.J.2    Tseng, C.J.3    Tung, C.S.4
  • 30
    • 0031035072 scopus 로고    scopus 로고
    • Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax
    • Huff R. A., Vaughn R. A., Kuhar M. J. and Uhl G. R. (1997) Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax. J. Neurochem. 68, 225-232.
    • (1997) J. Neurochem. , vol.68 , pp. 225-232
    • Huff, R.A.1    Vaughn, R.A.2    Kuhar, M.J.3    Uhl, G.R.4
  • 33
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 34
    • 0035066885 scopus 로고    scopus 로고
    • Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
    • Lee F. J. S., Liu F., Pristupa Z. B. and Niznik H. B. (2001) Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J. 15, 916-926.
    • (2001) FASEB J. , vol.15 , pp. 916-926
    • Lee, F.J.S.1    Liu, F.2    Pristupa, Z.B.3    Niznik, H.B.4
  • 35
    • 0035503064 scopus 로고    scopus 로고
    • Regulation of NMDA receptor activity by F-actin and myosin light chain kinase
    • Lei S., Czerwinska E., Cserwinski W., Walsh M. P. and MacDonald J. F. (2001) Regulation of NMDA receptor activity by F-actin and myosin light chain kinase. J. Neurosci. 21, 8464-8472.
    • (2001) J. Neurosci. , vol.21 , pp. 8464-8472
    • Lei, S.1    Czerwinska, E.2    Cserwinski, W.3    Walsh, M.P.4    MacDonald, J.F.5
  • 37
    • 0033568870 scopus 로고    scopus 로고
    • Membrane trafficking regulates the activity of the human dopamine transporter
    • Melikian H. E. and Buckley K. M. (1999) Membrane trafficking regulates the activity of the human dopamine transporter. J. Neurosci. 19, 7699-7710.
    • (1999) J. Neurosci. , vol.19 , pp. 7699-7710
    • Melikian, H.E.1    Buckley, K.M.2
  • 38
    • 0027979190 scopus 로고
    • The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation
    • Milner H. E., Beliveau R. and Jarvis S. M. (1994) The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation. Biochim. Biophys. Acta 1190, 185-187.
    • (1994) Biochim. Biophys. Acta , vol.1190 , pp. 185-187
    • Milner, H.E.1    Beliveau, R.2    Jarvis, S.M.3
  • 39
    • 0028302065 scopus 로고
    • Inhibition of agonist-stimulated inositol 1,4,5-triphosphate production and calcium signaling by the myosin light chain kinase inhibitor, wortmannin
    • Nakanish S., Catt K. J. and Balla T. (1994) Inhibition of agonist-stimulated inositol 1,4,5-triphosphate production and calcium signaling by the myosin light chain kinase inhibitor, wortmannin. J. Biol. Chem. 269, 6528-6535.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6528-6535
    • Nakanish, S.1    Catt, K.J.2    Balla, T.3
  • 40
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow C. W. (1993) A radical hypothesis for neurodegeneration. Trends Neurosci. 16, 439-444.
    • (1993) Trends Neurosci. , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 42
    • 0036616838 scopus 로고    scopus 로고
    • Peroxynitrite inactivates the human dopamine transporter by modification of Cys342: Potential mechanism of neurotoxicity in dopamine neurons
    • Park S. U., Ferrer J. V., Javitch J. A. and Kuhn D. M. (2002) Peroxynitrite inactivates the human dopamine transporter by modification of Cys342: potential mechanism of neurotoxicity in dopamine neurons. J. Neurosci. 22, 4399-4405.
    • (2002) J. Neurosci. , vol.22 , pp. 4399-4405
    • Park, S.U.1    Ferrer, J.V.2    Javitch, J.A.3    Kuhn, D.M.4
  • 44
    • 0004217575 scopus 로고
    • John Wiley & Sons: New York
    • Segel I. H. (1976) Biochemical Calculations, pp. 218-323. John Wiley & Sons: New York.
    • (1976) Biochemical Calculations , pp. 218-323
    • Segel, I.H.1
  • 45
    • 0035942203 scopus 로고    scopus 로고
    • Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer
    • Shyue S. K., Tsai M. J., Liou J. Y., Willerson J. T. and Wu K. K. (2001) Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer. Circulation 103, 2090-2095.
    • (2001) Circulation , vol.103 , pp. 2090-2095
    • Shyue, S.K.1    Tsai, M.J.2    Liou, J.Y.3    Willerson, J.T.4    Wu, K.K.5
  • 47
    • 0032526940 scopus 로고    scopus 로고
    • The regulation of reactive oxygen species production during programmed cell death
    • Tan S., Sagara Y., Liu Y., Maher P. and Schubert D. (1998) The regulation of reactive oxygen species production during programmed cell death. J. Cell Biol. 141, 1423-1432.
    • (1998) J. Cell Biol. , vol.141 , pp. 1423-1432
    • Tan, S.1    Sagara, Y.2    Liu, Y.3    Maher, P.4    Schubert, D.5
  • 48
    • 0021189292 scopus 로고
    • Relationship between an altered membrane form and a low affinity form of the β-adrenergic receptor occurring during catecholamine-induced desensitization: Evidence for receptor internalization
    • Toews M. L., Waldo G. L., Harden T. K. and Perkins J. P. (1984) Relationship between an altered membrane form and a low affinity form of the β-adrenergic receptor occurring during catecholamine-induced desensitization: evidence for receptor internalization. J. Biol. Chem. 259, 11844-11850.
    • (1984) J. Biol. Chem. , vol.259 , pp. 11844-11850
    • Toews, M.L.1    Waldo, G.L.2    Harden, T.K.3    Perkins, J.P.4
  • 49
    • 0035026044 scopus 로고    scopus 로고
    • Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1
    • Torres G. E., Yao W. D., Mohn A. R., Quan H., Kim K. M., Levey A. I., Staudinger J. and Caron M. G. (2001) Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron 30, 121-134.
    • (2001) Neuron , vol.30 , pp. 121-134
    • Torres, G.E.1    Yao, W.D.2    Mohn, A.R.3    Quan, H.4    Kim, K.M.5    Levey, A.I.6    Staudinger, J.7    Caron, M.G.8
  • 51
    • 0032145886 scopus 로고    scopus 로고
    • Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?
    • Trotti D., Danbolt N. C. and Volterra A. (1998) Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol. Sci. 19, 328-334.
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 328-334
    • Trotti, D.1    Danbolt, N.C.2    Volterra, A.3
  • 52
    • 0033366461 scopus 로고    scopus 로고
    • SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter
    • Trotti D., Rolfs A., Danbolt N. C., Brown R. H. Jr and Hediger M. (1999) SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter. Nat. Neurosci. 2, 427-433.
    • (1999) Nat. Neurosci. , vol.2 , pp. 427-433
    • Trotti, D.1    Rolfs, A.2    Danbolt, N.C.3    Brown R.H., Jr.4    Hediger, M.5
  • 53
  • 55
    • 0033529675 scopus 로고    scopus 로고
    • Reactive oxygen species mediated the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells
    • Ushio-Fukai M., Alexander R. W., Akers M., Yin Q., Fujio Y., Walsh K. and Griendling K. K. (1999) Reactive oxygen species mediated the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. J. Biol. Chem. 274, 22699-22704.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22699-22704
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Yin, Q.4    Fujio, Y.5    Walsh, K.6    Griendling, K.K.7
  • 56
    • 0030972751 scopus 로고    scopus 로고
    • Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
    • Vaughan R. A., Huff R. A., Uhl G. R. and Kuhar M. J. (1997) Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes. J. Biol. Chem. 272, 15541-15546.
    • (1997) J. Biol. Chem. , vol.272 , pp. 15541-15546
    • Vaughan, R.A.1    Huff, R.A.2    Uhl, G.R.3    Kuhar, M.J.4
  • 57
    • 0028208495 scopus 로고
    • Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes
    • Volterra A., Trotti D., Tromba C., Floridi S. and Racagni G. (1994) Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes. J. Neurosci. 14, 2924-2932.
    • (1994) J. Neurosci. , vol.14 , pp. 2924-2932
    • Volterra, A.1    Trotti, D.2    Tromba, C.3    Floridi, S.4    Racagni, G.5
  • 58
    • 0028893637 scopus 로고
    • Localization of damage induced by reactive oxygen species in cultured cells
    • Vroegop S. M., Decker D. E. and Buxser S. E. (1995) Localization of damage induced by reactive oxygen species in cultured cells. Free Rad. Biol. Med. 18, 141-151.
    • (1995) Free Rad. Biol. Med. , vol.18 , pp. 141-151
    • Vroegop, S.M.1    Decker, D.E.2    Buxser, S.E.3
  • 59
    • 0034655674 scopus 로고    scopus 로고
    • Mechanisms of hydrogen peroxide-induced calcium dysregulation in PC12 cells
    • Wang H. and Joseph J. A. (2000) Mechanisms of hydrogen peroxide-induced calcium dysregulation in PC12 cells. Free Rad. Biol. Med. 28, 1222-1231.
    • (2000) Free Rad. Biol. Med. , vol.28 , pp. 1222-1231
    • Wang, H.1    Joseph, J.A.2
  • 60
    • 0028872648 scopus 로고
    • Dopamine transporter cysteine mutants: Second extracellular loop cysteines are required for transporter expression
    • Wang J. B., Moriwaki A. and Uhl G. R. (1995) Dopamine transporter cysteine mutants: second extracellular loop cysteines are required for transporter expression. J. Neurochem. 64, 1416-1419.
    • (1995) J. Neurochem. , vol.64 , pp. 1416-1419
    • Wang, J.B.1    Moriwaki, A.2    Uhl, G.R.3
  • 61
    • 0035112815 scopus 로고    scopus 로고
    • Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter
    • Whitehead R. E., Ferrer J. V., Javitch J. A. and Justice J. B. (2001) Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter. J. Neurochem. 76, 1242-1251.
    • (2001) J. Neurochem. , vol.76 , pp. 1242-1251
    • Whitehead, R.E.1    Ferrer, J.V.2    Javitch, J.A.3    Justice, J.B.4
  • 62
    • 0027374488 scopus 로고
    • Inhibition of histamine secretion by wortmannin through the blockade of phosphatidyl-inositol 3-kinase in RBL-2H3 cells
    • Yano H., Nakanishi S., Kimura K., Hanai N., Saitoh Y., Fukui Y., Nonomura Y. and Matsuda Y. (1993) Inhibition of histamine secretion by wortmannin through the blockade of phosphatidyl-inositol 3-kinase in RBL-2H3 cells. J. Biol. Chem. 268, 25846-25856.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25846-25856
    • Yano, H.1    Nakanishi, S.2    Kimura, K.3    Hanai, N.4    Saitoh, Y.5    Fukui, Y.6    Nonomura, Y.7    Matsuda, Y.8
  • 63
    • 0030936222 scopus 로고    scopus 로고
    • Regulation of the functional activity of the human dopamine transporter by protein kinase C
    • Zhang L., Coffey L. L. and Reith M. E. (1997) Regulation of the functional activity of the human dopamine transporter by protein kinase C. Biochem. Pharmacol. 53, 667-688.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 667-688
    • Zhang, L.1    Coffey, L.L.2    Reith, M.E.3
  • 64
    • 0030922926 scopus 로고    scopus 로고
    • Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter in Xenopus oocytes
    • Zhu S. J., Kavanaugh M. P., Sonders M. S., Amara S. M. and Zahniser N. R. (1997) Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter in Xenopus oocytes. J. Pharmacol. Exp. Ther. 282, 1358-1356.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1358-1356
    • Zhu, S.J.1    Kavanaugh, M.P.2    Sonders, M.S.3    Amara, S.M.4    Zahniser, N.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.