A subset of metzincins and related genes constitutes a marker of human solid organ fibrosis

Virchows Archiv

Volumn 458, Issue 4, 2011, Pages 487-496

  Rödder, Silke ^a   Scherer, Andreas ^b   Körner, Meike ^a   Marti, Hans Peter ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b Spheromics ^*  (Finland)

Author keywords

Classifier; Fibrosis; Metzincins and related genes (MARGS); Microarray

Indexed keywords

TRANSCRIPTOME;

ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROSING ALVEOLITIS; FIBROSIS; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ANALYSIS; HEART FAILURE; HUMAN; HUMAN TISSUE; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; LIVER CIRRHOSIS; MALE; METZINCIN GENE; MICROARRAY ANALYSIS; PANCREATITIS; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADAM PROTEINS; ALGORITHMS; AREA UNDER CURVE; BIOLOGICAL MARKERS; FIBROSIS; GENE EXPRESSION PROFILING; HEART DISEASES; HUMANS; KIDNEY DISEASES; LIVER DISEASES; LUNG DISEASES; MATRIX METALLOPROTEINASES; METALLOENDOPEPTIDASES; MICROARRAY ANALYSIS; PANCREATIC DISEASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROC CURVE;

EID: 79956191654     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-011-1052-7     Document Type: Article

References (35)

1. Roedder S, Scherer A, Raulf F, Berthier CC, Hertig A, Couzi L, Durrbach A, Rondeau E, Marti HP (2009) Renal allografts with IF/TA display distinct expression profiles of metzincins and related genes. Am J Transplant 9:517-526
2. Meneghin A, Hogaboam CM (2007) Infectious disease, the innate immune response, and fibrosis. J Clin Invest 117:530-538 (Pubitemid 46348507)
3. Selman M, King TE, Pardo A (2001) Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 134:136-151 (Pubitemid 32096342)
4. Nagase H, Woessner JF Jr (1999) Matrix metalloproteinases. J Biol Chem 274:21491-21494 (Pubitemid 129519680)
5. Woessner JF Jr, Gunja-Smith Z (1991) Role of metalloproteinases in human osteoarthritis. J Rheumatol Suppl 27:99-101
6. Rodwell GE, Sonu R, Zahn JM, Lund J, Wilhelmy J, Wang L, Xiao W, Mindrinos M, Crane E, Segal E, Myers BD, Brooks JD, Davis RW, Higgins J, Owen AB, Kim SK (2004) A transcriptional profile of aging in the human kidney. PLoS Biol 2:e427
7. Hannenhalli S, Putt ME, Gilmore JM, Wang J, Parmacek MS, Epstein JA, Morrisey EE, Margulies KB, Cappola TP (2006) Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation 114:1269-1276 (Pubitemid 44402052)
8. Konishi K, Gibson KF, Lindell KO, Richards TJ, Zhang Y, Dhir R, Bisceglia M, Gilbert S, Yousem SA, Song JW, Kim DS, Kaminski N (2009) Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 180:167-175
9. Utsunomiya T, Okamoto M, Wakiyama S, Hashimoto M, Fukuzawa K, Ezaki T, Aishima S, Yoshikawa Y, Hanai T, Inoue H, Barnard GF, Mori M (2007) A specific gene-expression signature quantifies the degree of hepatic fibrosis in patients with chronic liver disease. World J Gastroenterol 13:383-390 (Pubitemid 46178972)
10. Binkley CE, Zhang L, Greenson JK, Giordano TJ, Kuick R, Misek D, Hanash S, Logsdon CD, Simeone DM (2004) The molecular basis of pancreatic fibrosis: common stromal gene expression in chronic pancreatitis and pancreatic adenocarcinoma. Pancreas 29:254-263 (Pubitemid 40228270)
11. Sing T, Sander O, Beerenwinkel N, Lengauer T (2005) ROCR: visualizing classifier performance in R. Bioinformatics 21:3940-3941 (Pubitemid 41535515)
12. Vandesompele J, De PK, Pattyn F, Poppe B, Van RN, De PA, Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034
13. Zaoui P, Cantin JF, Alimardani-Bessette M, Monier F, Halimi S, Morel F, Cordonnier D (2000) Role of metalloproteases and inhibitors in the occurrence and progression of diabetic renal lesions. Diabetes Metab 26(Suppl 4):25-29 (Pubitemid 30618353)
14. Klein T, Bischoff R (2010) Physiology and pathophysiology of matrix metalloproteases. Amino Acids. doi:10.1007/s00726-010-0689-x
15. Klein T, Geurink P, Overkleeft S, Kauffman K, Bischoff R (2009) Functional proteomics on zinc-dependent metalloproteinases using inhibitor probes. ChemMedChem 4:164-170
16. Berthier CC, Pally C, Weckbecker G, Raulf F, Rehrauer H, Wagner U, Le HM, Marti HP (2009) Experimental heart transplantation: effect of cyclosporine on expression and activity of metzincins. Swiss Med Wkly 139:233-240
17. Tanaka T, Kato H, Kojima I, Ohse T, Son D, Tawakami T, Yatagawa T, Inagi R, Fujita T, Nangaku M (2006) Hypoxia and expression of hypoxia-inducible factor in the aging kidney. J Gerontol A Biol Sci Med Sci 61:795-805 (Pubitemid 44260161)
18. Fine LG, Norman JT (2008) Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics. Kidney Int 74:867-872
19. Leung PS (2007) The physiology of a local renin-angiotensin system in the pancreas. J Physiol 580:31-37
20. Corte TJ, Wort SJ, Wells AU (2009) Pulmonary hypertension in idiopathic pulmonary fibrosis: a review. Sarcoidosis Vasc Diffuse Lung Dis 26:7-19
21. Zhou G, Dada LA, Wu M, Kelly A, Trejo H, Zhou Q, Varga J, Sznajder JI (2009) Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1. Am J Physiol Lung Cell Mol Physiol 297:L1120-L1130
22. Tamamori M, Ito H, Hiroe M, Marumo F, Hata RI (1997) Stimulation of collagen synthesis in rat cardiac fibroblasts by exposure to hypoxic culture conditions and suppression of the effect by natriuretic peptides. Cell Biol Int 21:175-180 (Pubitemid 27202301)
23. de Boer RA, Pinto YM, van Veldhuisen DJ (2003) The imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: the role of microvascular growth and abnormalities. Microcirculation 10:113-126 (Pubitemid 39004240)
24. Gramley F, Lorenzen J, Jedamzik B, Gatter K, Koellensperger E, Munzel T, Pezzella F (2010) Atrial fibrillation is associated with cardiac hypoxia. Cardiovasc Pathol 19:102-111
25. Rosmorduc O, Housset C (2010) Hypoxia: a link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease. Semin Liver Dis 30:258-270
26. Copple BL, Bai S, Moon JO (2010) Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic Kupffer cells. Hepatol Res 40:530-539
27. Corpechot C, Barbu V, Wendum D, Kinnman N, Rey C, Poupon R, Housset C, Rosmorduc O (2002) Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. Hepatology 35:1010-1021 (Pubitemid 34453998)
28. Takahara Y, Takahashi M, Zhang QW, Wagatsuma H, Mori M, Tamori A, Shiomi S, Nishiguchi S (2008) Serial changes in expression of functionally clustered genes in progression of liver fibrosis in hepatitis C patients. World J Gastroenterol 14:2010-2022 (Pubitemid 351795820)
29. Hui AY, Friedman SL (2003) Molecular basis of hepatic fibrosis. Expert Rev Mol Med 5:1-23
30. Halloran PF, Reeve J, Kaplan B (2006) Lies, damn lies, and statistics: the perils of the P value. Am J Transplant 6:10-11 (Pubitemid 43382194)
31. Korosoglou G, Humpert PM (2007) Non-invasive diagnostic imaging techniques as a window into the diabetic heart: a review of experimental and clinical data. Exp Clin Endocrinol Diabetes 115:211-220 (Pubitemid 46762247)
32. Tatsumi C, Kudo M, Ueshima K, Kitai S, Ishikawa E, Yada N, Hagiwara S, Inoue T, Minami Y, Chung H, Maekawa K, Fujimoto K, Kato M, Tonomura A, Mitake T, Shiina T (2010) Non-invasive evaluation of hepatic fibrosis for type C chronic hepatitis. Intervirology 53:76-81
33. Tham RT, Heyerman HG, Falke TH, Zwinderman AH, Bloem JL, Bakker W, Lamers CB (1991) Cystic fibrosis: MR imaging of the pancreas. Radiology 179:183-186
34. van den Blink B, Wijsenbeek MS, Hoogsteden HC (2010) Serum biomarkers in idiopathic pulmonary fibrosis. Pulm Pharmacol Ther 23:515-520
35. Ahmed SH, Clark LL, Pennington WR, Webb CS, Bonnema DD, Leonardi AH, McClure CD, Spinale FG, Zile MR (2006) Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease. Circulation 113:2089-2096