The efficiency of intratympanic dexamethasone injection as a sequential treatment after initial systemic steroid therapy for sudden sensorineural hearing loss

European Archives of Oto-Rhino-Laryngology

Volumn 268, Issue 6, 2011, Pages 833-839

  Lee, Jong Bin ^a   Choi, Seong Jun ^a   Park, Keehyun ^b   Park, Hun Yi ^b   Choo, Oak Sung ^b   Choung, Yun Hoon ^b  

^a Konyang University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

Author keywords

Dexamethasone; Hearing; Injection; Sudden hearing loss; Tympanum

Indexed keywords

DEXAMETHASONE; GINKGO BILOBA EXTRACT; STEROID;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG TREATMENT FAILURE; FEMALE; GENERAL CONDITION IMPROVEMENT; HUMAN; LOW FREQUENCY NOISE; MALE; MIXED HEARING LOSS; PRIORITY JOURNAL; PURE TONE AUDIOMETRY; RANDOMIZED CONTROLLED TRIAL; REST; SMOKING CESSATION; SODIUM RESTRICTION; SOUND LEVEL MEASUREMENT; TREATMENT RESPONSE;

ADMINISTRATION, ORAL; ADULT; AUDIOMETRY, PURE-TONE; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOLLOW-UP STUDIES; GLUCOCORTICOIDS; HEARING; HEARING LOSS, SENSORINEURAL; HEARING LOSS, SUDDEN; HUMANS; INJECTIONS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TREATMENT OUTCOME; TYMPANIC MEMBRANE;

EID: 79956160376     PISSN: 09374477     EISSN: 14344726     Source Type: Journal    
DOI: 10.1007/s00405-010-1476-8     Document Type: Article

References (22)

1. Wilson WR, Byl FM, Laird N (1980) The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol 106:772-776 (Pubitemid 11194190)
2. Chen CY, Halpin C, Rauch SD (2003) Oral steroid treatment of sudden sensorineural hearing loss: a ten year retrospective analysis. Otol Neurotol 24:728-733 (Pubitemid 37122536)
3. Conlin AE, Parnes LS (2007) Treatment of sudden sensorineural hearing loss: I. A systematic review. Arch Otolaryngol Head Neck Surg 133:573-581 (Pubitemid 46974887)
4. Gianoli GJ, Li JC (2001) Transtympanic steroids for treatment of sudden hearing loss. Otolaryngol Head Neck Surg 125:142-146 (Pubitemid 33662658)
5. Kakehata S, Sasaki A, Oji K, Futai K, Ota S, Makinae K et al (2006) Comparison of intratympanic and intravenous dexamethasone treatment on sudden sensorineural hearing loss with diabetes. Otol Neurotol 27:604-608 (Pubitemid 44180470)
6. Hamid M, Trune D (2008) Issues, indications, and controversies regarding intratympanic steroid perfusion. Curr Opin Otolaryngol Head Neck Surg 16:434-440
7. Haynes DS, O'Malley M, Cohen S, Watford K, Labadie RF (2007) Intratympanic dexamethasone for sudden sensorineural hearing loss after failure of systemic therapy. Laryngoscope 117:3-15 (Pubitemid 46066055)
8. Plaza G, Herráiz C (2007) Intratympanic steroids for treatment of sudden hearing loss after failure of intravenous therapy. Otolaryngol Head Neck Surg 137:74-78 (Pubitemid 46962140)
9. Choung YH, Park K, Shin YR, Cho MJ (2006) Intratympanic dexamethasone injection for refractory sudden sensorineural hearing loss. Laryngoscope 116:747-752 (Pubitemid 44318031)
10. Silverstein H, Choo D, Rosenberg SI, Kuhn J, Seidman M, Stein I (1996) Intratympanic steroid treatment of inner ear disease and tinnitus (preliminary report). Ear Nose Throat J 75:468-471
11. Xenellis J, Papadimitriou N, Nikolopoulos T, Maragoudakis P, Segas J, Tzagaroulakis A et al (2006) Intratympanic steroid treatment in idiopathic sudden sensorineural hearing loss: a control study. Otolaryngol Head Neck Surg 134:940-945 (Pubitemid 43766563)
12. Roebuck J, Chang CY (2006) Efficacy of steroid injection on idiopathic sudden sensorineural hearing loss. Otolaryngol Head Neck Surg 135:276-279 (Pubitemid 44142144)
13. Gouveris H, Selivanova O, Mann W (2005) Intratympanic dexamethasone with hyaluronic acid in the treatment of idiopathic sudden sensorineural hearing loss after failure of intravenous steroid and vasoactive therapy. Eur Arch Otorhinolaryngol 262:131-134 (Pubitemid 40386323)
14. Fitzgerald DC, McGuire JF (2007) Intratympanic steroids for idiopathic sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol 116:253-256 (Pubitemid 46651179)
15. Ahn JH, Yoo MH, Yoon TH, Chung JW (2008) Can intratympanic dexamethasone added to systemic steroids improve hearing outcome in patients with sudden deafness? Laryngoscope 118:279-282
16. Battaglia A, Burchette R, Cueva R (2008) Combination therapy (intratympanic dexamethasone + high-dose prednisone taper) for the treatment of idiopathic sudden sensorineural hearing loss. Otol Neurotol 29:453-460
17. Plontke SK, Löwenheim H, Mertens J, Engel C, Meisner C, Weidner A et al (2009) Randomized, double blind, placebo controlled trial on the safety and efficacy of continuous intratympanic dexamethasone delivered via a round window catheter for severe to profound sudden idiopathic sensorineural hearing loss after failure of systemic therapy. Laryngoscope 119:359-369
18. Ahn JH, Han MW, Kim JH, Chung JW, Yoon TH (2008) Therapeutic effectiveness over time of intratympanic dexamethasone as salvage treatment of sudden deafness. Acta Otolaryngol 128:128-131
19. Selivanova OA, Gouveris H, Victor A, Amedee RG, Mann W (2005) Intratympanic dexamethasone and hyaluronic acid in patients with low-frequency and Meniere's associated sudden sensorineural hearing loss. Otol Neurotol 26:890-895 (Pubitemid 41330703)
20. Choung YH, Taura A, Pak K, Choi SJ, Masuda M, Ryan AF (2009) Generation of highly-reactive oxygen species is closely related to hair cell damage in rat organ of Corti treated with gentamicin. Neuroscience 161:214-226
21. Lim HW, Choi SH, Kang HH, Ahn JH, Chung JW (2008) Apoptotic pattern of cochlear outer hair cells and frequency-specific hearing threshold shift in noise-exposed BALB/c mice. Clin Exp Otorhinolaryngol 1:80-85
22. Sha SH, Taylor R, Forge A, Schacht J (2001) Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals. Hear Res 155:1-8 (Pubitemid 32401586)