Randomized, double blind, placebo controlled trial on the safety and efficacy of continuous intratympanic dexamethasone delivered via a round window catheter for severe To profound sudden idiopathic sensorineural hearing loss after failure of systemic therapy

Laryngoscope

Volumn 119, Issue 2, 2009, Pages 359-369

  Plontke, Stefan K ^a   Löwenheim, Hubert ^a   Mertens, Jürgen ^b   Engel, Corinna ^a   Meisner, Christoph ^a   Weidner, Andy ^b   Zimmermann, Rainer ^a   Preyer, Serena ^a   Koitschev, Assen ^a   Zenner, Hans Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b St Vincentius Hospital   (Germany)

Author keywords

Dexamethasone; Glucocorticoids; Human; Inner ear; Intratympanic; Randomized controlled trial; Steroids; Sudden hearing loss

Indexed keywords

DEXAMETHASONE; DEXAMETHASONE SODIUM PHOSPHATE; PLACEBO; GLUCOCORTICOID;

ADULT; AGED; ARTICLE; AUDITORY THRESHOLD; CATHETER; CLINICAL TRIAL; COCHLEA FENESTRA; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; EAR CANAL SKIN DEFECT; EARDRUM PERFORATION; FEMALE; FOLLOW UP; HEADACHE; HEARING IMPAIRMENT; HUMAN; IDIOPATHIC DISEASE; INNER EAR; MAJOR CLINICAL STUDY; MALE; OTALGIA; OUTCOME ASSESSMENT; PERCEPTION DEAFNESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN DEFECT; SPEECH DISCRIMINATION; STATISTICAL ANALYSIS; SYSTEMIC THERAPY; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT RESPONSE; VERTIGO; AUDIOMETRY; CATHETERIZATION; DRUG ADMINISTRATION ROUTE; MIDDLE AGED; MULTICENTER STUDY; SUDDEN DEAFNESS;

ADULT; AGED; AUDIOMETRY; CATHETERIZATION; DEXAMETHASONE; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION ROUTES; FEMALE; GLUCOCORTICOIDS; HEARING LOSS, SENSORINEURAL; HEARING LOSS, SUDDEN; HUMANS; MALE; MIDDLE AGED; PLACEBOS; ROUND WINDOW, EAR; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 63249122719     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1002/lary.20074     Document Type: Article

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