메뉴 건너뛰기




Volumn 18, Issue 6, 2011, Pages 545-550

Effect of aminoguanidine in sperm DNA fragmentation in varicocelized rats: Role of nitric oxide

Author keywords

aminoguanidine; rat; sperm chromatin; varicocele

Indexed keywords

ACRIDINE ORANGE; AMINOGUANIDINE; NITRIC OXIDE; PLACEBO;

EID: 79956158524     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719110393028     Document Type: Article
Times cited : (28)

References (47)
  • 1
    • 0041522560 scopus 로고    scopus 로고
    • Role of sperm chromatin abnormalities and DNA damage in male infertility
    • DOI 10.1093/humupd/dmg027
    • Agarwal A, Said TM. Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update. 2003 ; 9 (4). 331-345 (Pubitemid 36987282)
    • (2003) Human Reproduction Update , vol.9 , Issue.4 , pp. 331-345
    • Agarwal, A.1    Said, T.M.2
  • 2
    • 0348110637 scopus 로고    scopus 로고
    • Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele
    • DOI 10.1016/S0015-0282(03)02211-8
    • Saleh RA, Agarwal A, Sharma RK, Said TM, Sikka SC, Thomas AJ. Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele. Fertil Steril. 2003 ; 80 (6). 1431-1436 (Pubitemid 37532458)
    • (2003) Fertility and Sterility , vol.80 , Issue.6 , pp. 1431-1436
    • Saleh, R.A.1    Agarwal, A.2    Sharma, R.K.3    Said, T.M.4    Sikka, S.C.5    Thomas Jr., A.J.6
  • 3
    • 61449176080 scopus 로고    scopus 로고
    • Seminal reactive oxygen species-antioxidant relationship in fertile males with and without varicocele
    • Mostafa T, Anis T, Imam H, El-Nashar AR, Osman IA. Seminal reactive oxygen species-antioxidant relationship in fertile males with and without varicocele. Andrologia. 2009 ; 41 (2). 125-129
    • (2009) Andrologia , vol.41 , Issue.2 , pp. 125-129
    • Mostafa, T.1    Anis, T.2    Imam, H.3    El-Nashar, A.R.4    Osman, I.A.5
  • 6
    • 3042697476 scopus 로고    scopus 로고
    • The potential role of inducible nitric oxide synthase (iNOS) activity in the testicular dysfunction associated with varicocele: An experimental study
    • DOI 10.1023/B:UROL.0000032687.58462.4f
    • Turker Koksal I, Erdoǧru T, Gülkesen H, et al. The potential role of inducible nitric oxide synthase (iNOS) activity in the testicular dysfunction associated with varicocele: an experimental study. Int Urol Nephrol. 2004 ; 36 (1). 67-72 (Pubitemid 38867818)
    • (2004) International Urology and Nephrology , vol.36 , Issue.1 , pp. 67-72
    • Koksal, I.T.1    Erdogru, T.2    Gulkesen, H.3    Sezer, C.4    Usta, M.5    Ciftcioglu, A.6    Baykara, M.7
  • 7
    • 65449159367 scopus 로고    scopus 로고
    • Role of antioxidants in the treatment of male infertility
    • Kefer JC, Agarwal A, Sabanegh E. Role of antioxidants in the treatment of male infertility. Int J Urol. 2009 ; (16). 449-457
    • (2009) Int J Urol , Issue.16 , pp. 449-457
    • Kefer, J.C.1    Agarwal, A.2    Sabanegh, E.3
  • 9
    • 4043134464 scopus 로고    scopus 로고
    • The role of reactive oxygen species and apoptosis in the pathogenesis of varicocele in a rat model and efficiency of vitamin E treatment
    • DOI 10.1111/j.1365-2605.2004.00476.x
    • Cam K, Simsek F, Yuksel M, et al. The role of reactive oxygen species and apoptosis in the pathogenesis of varicocele in a rat model and efficiency of vitamin E treatment. Int J Androl. 2004 ; 27 (4). 228-233 (Pubitemid 39062084)
    • (2004) International Journal of Andrology , vol.27 , Issue.4 , pp. 228-233
    • Cam, K.1    Simsek, F.2    Yuksel, M.3    Turker, L.4    Haklar, G.5    Yalcin, S.6    Akdas, A.7
  • 10
    • 58449108109 scopus 로고    scopus 로고
    • Predictors of improved seminal characteristics by varicocele repair
    • Kondo Y, Ishikawa T, Yamaguchi K, Fujisawa M. Predictors of improved seminal characteristics by varicocele repair. Andrologia. 2009 ; 41 (1). 20-23
    • (2009) Andrologia , vol.41 , Issue.1 , pp. 20-23
    • Kondo, Y.1    Ishikawa, T.2    Yamaguchi, K.3    Fujisawa, M.4
  • 11
    • 0030938584 scopus 로고    scopus 로고
    • Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage
    • DOI 10.1074/jbc.272.14.9030
    • Szabo C, Ferrer-Sueta G, Zingarelli B, Southan GJ, Salzman AL, Radi R. Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage. J Biol Chem. 1997 ; 272 (14). 9030-9036 (Pubitemid 27154903)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.14 , pp. 9030-9036
    • Szabo, C.1    Ferrer-Sueta, G.2    Zingarelli, B.3    Southan, G.J.4    Salzman, A.L.5    Radi, R.6
  • 14
    • 79956123090 scopus 로고    scopus 로고
    • The relationship between oxidative stress and sperm damage in normozoospermic men and men with abnormal sperm parameters
    • Lakpour N, Kharrazi H, Akhondi MA, et al. The relationship between oxidative stress and sperm damage in normozoospermic men and men with abnormal sperm parameters. TUMJ. 2008 ; 65 (3). 11-19
    • (2008) TUMJ , vol.65 , Issue.3 , pp. 11-19
    • Lakpour, N.1    Kharrazi, H.2    Akhondi, M.A.3
  • 15
    • 36549024981 scopus 로고    scopus 로고
    • Clinical relevance of oxidative stress and sperm chromatin damage in male infertility: An evidence based analysis
    • Cocuzza M, Sikka SC, Athayde KS, Agarwal A. Clinical relevance of oxidative stress and sperm chromatin damage in male infertility: an evidence based analysis. Int Braz J Urol. 2007 ; 33 (5). 603-621
    • (2007) Int Braz J Urol , vol.33 , Issue.5 , pp. 603-621
    • Cocuzza, M.1    Sikka, S.C.2    Athayde, K.S.3    Agarwal, A.4
  • 16
    • 79956113812 scopus 로고    scopus 로고
    • Evaluation of male fertility potential by Toluidine Blue test for sperm chromatin structure assessment
    • Tsarev I, Bungum M, Giwercman A, et al. Evaluation of male fertility potential by Toluidine Blue test for sperm chromatin structure assessment. Hum Reprod. 2009 ; 1 (1). 1-6
    • (2009) Hum Reprod , vol.1 , Issue.1 , pp. 1-6
    • Tsarev, I.1    Bungum, M.2    Giwercman, A.3
  • 18
    • 0030476010 scopus 로고    scopus 로고
    • The effect of chromatin condensation (Aniline Blue staining) and morphology (strict criteria) of human spermatozoa on fertilization, cleavage and pregnancy rates in an intracytoplasmic sperm injection programme
    • Hammadeh ME, al-Hasani S, Stieber M, et al. The effect of chromatin condensation (Aniline Blue staining) and morphology (strict criteria) of human spermatozoa on fertilization, cleavage and pregnancy rates in an intracytoplasmic sperm injection programme. Hum Reprod Update. 1996 ; 11 (11). 2468-2471
    • (1996) Hum Reprod Update , vol.11 , Issue.11 , pp. 2468-2471
    • Hammadeh, M.E.1    Al-Hasani, S.2    Stieber, M.3
  • 19
    • 63249115710 scopus 로고    scopus 로고
    • Pentoxifylline and antioxidants improve sperm quality in male patients with varicocele
    • Oliva A, Dotta A, Multigner L. Pentoxifylline and antioxidants improve sperm quality in male patients with varicocele. Fertil Steril. 2009 ; 91 (suppl 4). 1536-1539
    • (2009) Fertil Steril , vol.91 , Issue.SUPPL. 4 , pp. 1536-1539
    • Oliva, A.1    Dotta, A.2    Multigner, L.3
  • 20
    • 0031840305 scopus 로고    scopus 로고
    • Reactive oxygen species: Potential cause for DNA fragmentation in human spermatozoa
    • DOI 10.1093/humrep/13.4.896
    • Lopes S, Jurisicova A, Sun JG, Casper RF. Reactive oxygen species: potential cause for DNA fragmentation in human spermatozoa. Hum Reprod. 1998 ; 13 (4). 896-900 (Pubitemid 28239194)
    • (1998) Human Reproduction , vol.13 , Issue.4 , pp. 896-900
    • Lopes, S.1    Jurisicova, A.2    Sun, J.-G.3    Casper, R.F.4
  • 21
    • 59649110295 scopus 로고    scopus 로고
    • 7-nitroindazole, but not L-NAME or aminoguanidine, attenuates anaphylactic hypotension in conscious rats
    • Zhang W, Shibamoto T, Cui S, Takano H, Kurata Y. 7-nitroindazole, but not L-NAME or aminoguanidine, attenuates anaphylactic hypotension in conscious rats. SHOCK. 2009 ; 2 (31). 201-206
    • (2009) SHOCK , vol.2 , Issue.31 , pp. 201-206
    • Zhang, W.1    Shibamoto, T.2    Cui, S.3    Takano, H.4    Kurata, Y.5
  • 22
    • 51449116419 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expressions in different lung injury models and the protective effect of aminoguanidine
    • Yeh DY, Feng NH, Chen CF, Lin HI, Wang D. Inducible nitric oxide synthase expressions in different lung injury models and the protective effect of aminoguanidine. Transplant Proc. 2008 ; 40 (7). 2178-2181
    • (2008) Transplant Proc , vol.40 , Issue.7 , pp. 2178-2181
    • Yeh, D.Y.1    Feng, N.H.2    Chen, C.F.3    Lin, H.I.4    Wang, D.5
  • 24
    • 0031961808 scopus 로고    scopus 로고
    • Nitric oxide suppression reversibly attenuates mitochondrial dysfunction and cholestasis in endotoxemic rat liver
    • DOI 10.1002/hep.510270118
    • Shiomi M, Wakabayashi Y, Sano T, et al. Nitric oxide suppression reversibly attenuates mitochondrial dysfunction and cholestasis in endotoxemic rat liver. Hepatology. 1998 ; 27 (1). 108-115 (Pubitemid 28041542)
    • (1998) Hepatology , vol.27 , Issue.1 , pp. 108-115
    • Shiomi, M.1    Wakabayashi, Y.2    Sano, T.3    Shinoda, Y.4    Nimura, Y.5    Ishimura, Y.6    Suematsu, M.7
  • 25
    • 13044292629 scopus 로고    scopus 로고
    • Effect of aminoguanidine on lipid peroxidation in streptozotocin-induced diabetic rats
    • DOI 10.1016/S0026-0495(99)90128-2
    • Ihm SH, Park SW, Ihm J. Effect of aminoguanidine on lipid peroxidation in streptozotocin-induced diabetic rats. Metabolism. 1999 ; 48 (9). 1141-1145 (Pubitemid 29418284)
    • (1999) Metabolism: Clinical and Experimental , vol.48 , Issue.9 , pp. 1141-1145
    • Ihm, S.-H.1    Yoo, H.J.2    Park, S.W.3    Ihm, J.4
  • 27
    • 0035140035 scopus 로고    scopus 로고
    • The study of varicocele through the use of animal models
    • DOI 10.1093/humupd/7.1.78
    • Turner TT. The study of varicocele through the use of animal models. Hum Reprod Update. 2001 ; 7 (1). 78-84 (Pubitemid 32111973)
    • (2001) Human Reproduction Update , vol.7 , Issue.1 , pp. 78-84
    • Turner, T.T.1
  • 28
    • 33845321375 scopus 로고    scopus 로고
    • Effects of epidermal growth factor on sperm content and motility of rats with surgically induced varicoceles
    • DOI 10.1111/j.1745-7262.2006.00202.x
    • Cheng D, Zheng XM, Li SW, Yang ZW, Hu LQ. Effects of epidermal growth factor on sperm content and motility of rats with surgically induced varicoceles. Asian J Androl. 2006 ; 8 (6). 713-717 (Pubitemid 44869620)
    • (2006) Asian Journal of Andrology , vol.8 , Issue.6 , pp. 713-717
    • Cheng, D.1    Zheng, X.-M.2    Li, S.-W.3    Yang, Z.-W.4    Hu, L.-Q.5
  • 29
    • 0033397746 scopus 로고    scopus 로고
    • Normal sperm morphology and chromatin packaging: Comparison between aniline blue and chromomycin A3 staining
    • DOI 10.1046/j.1439-0272.1999.00290.x
    • Franken DR, Franken CJ, de la Guerre H, de Villiers A. Normal sperm morphology and chromatin packaging: comparison between aniline blue and chromomycin A3 staining. Andrologia. 1999 ; 31 (6). 361-366 (Pubitemid 30026288)
    • (1999) Andrologia , vol.31 , Issue.6 , pp. 361-366
    • Franken, D.R.1    Franken, C.J.2    De La Guerre, H.3    De Villiers, A.4
  • 30
    • 6344276831 scopus 로고    scopus 로고
    • Evaluation of chromatin integrity in human sperm using acridine orange staining with different fixatives and after cryopreservation
    • DOI 10.1111/j.1439-0272.2004.00626.x
    • Chohan KR, Griffin JT, Carrell DT. Evaluation of chromatin integrity in human sperm using acridine orange staining with different fixatives and after cryopreservation. Andrologia. 2004 ; 36 (5). 321-326 (Pubitemid 39389615)
    • (2004) Andrologia , vol.36 , Issue.5 , pp. 321-326
    • Chohan, K.R.1    Griffin, J.T.2    Carrell, D.T.3
  • 31
    • 0021255756 scopus 로고
    • A test for the practical evaluation of male fertility by acridine orange (AO) fluorescence
    • Tejada RI, Mitchell JC, Norman A, Marik JJ, Friedman S. A test for the practical evaluation of male fertility by acridine orange (AO) fluorescence. Fertil Steril. 1984 ; 42 (1). 87-91 (Pubitemid 14086156)
    • (1984) Fertility and Sterility , vol.42 , Issue.1 , pp. 87-91
    • Tejada, R.I.1    Mitchell, J.C.2    Norman, A.3
  • 32
    • 0036021442 scopus 로고    scopus 로고
    • Sperm single-stranded DNA, detected by acridine orange staining, reduces fertilization and quality of ICSI-derived embryos
    • DOI 10.1023/A:1016006509036
    • Virant-Klun I, Tomazevic T, Meden-Vrtovec H. Sperm single-stranded DNA, detected by acridine orange staining, reduces fertilization and quality of ICSI-derived embryos. J Assist Reprod Genet. 2002 ; 19 (7). 319-328 (Pubitemid 34831545)
    • (2002) Journal of Assisted Reproduction and Genetics , vol.19 , Issue.7 , pp. 319-328
    • Virant-Klun, I.1    Tomazevic, T.2    Meden-Vrtovec, H.3
  • 33
    • 39449122679 scopus 로고    scopus 로고
    • Comparison of nitric oxide concentration in seminal fluid between infertile patients with and without varicocele and normal fertile men
    • Mehraban D, Ansari M, Arab D. Comparison of nitric oxide concentration in seminal fluid between infertile patients with and without varicocele and normal fertile men. Urol J. 2005 ; 2 (2). 106-110
    • (2005) Urol J , vol.2 , Issue.2 , pp. 106-110
    • Mehraban, D.1    Ansari, M.2    Arab, D.3
  • 35
    • 47749128146 scopus 로고    scopus 로고
    • Effect of varicocele on chromatin condensation and DNA integrity of ejaculated spermatozoa using cytochemical tests
    • DOI 10.1111/j.1439-0272.2008.00852.x
    • Talebi AR, Moein MR, Tabibnejad N, Ghasemzadeh J. Effect of varicocele on chromatin condensation and DNA integrity of ejaculated spermatozoa using cytochemical tests. Andrologia. 2008 ; 40 (4). 245-251 (Pubitemid 352032760)
    • (2008) Andrologia , vol.40 , Issue.4 , pp. 245-251
    • Talebi, A.R.1    Moein, M.R.2    Tabibnejad, N.3    Ghasemzadeh, J.4
  • 36
    • 0038218497 scopus 로고    scopus 로고
    • Effects of melatonin on testicular tissue nitric oxide level and antioxidant enzyme activities in experimentally induced left varicocele
    • PII N24120314
    • Semercioz A, Onur R, Ogras S, Orhan I. Effects of melatonin on testicular tissue nitric oxide level and antioxidant enzyme activities in experimentally induced left varicocele. Neuro Endocrinol Lett. 2003 ; 24 (1-2). 86-90 (Pubitemid 36559507)
    • (2003) Neuroendocrinology Letters , vol.24 , Issue.1-2 , pp. 86-90
    • Semercioz, A.1    Onur, R.2    Ogras, S.3    Orhan, I.4
  • 37
    • 0034522557 scopus 로고    scopus 로고
    • The relationship between varicocele and semen nitric oxide concentrations
    • DOI 10.1007/s002400000132
    • Aksoy H, Aksoy Y, Özbey I, Altuntas I, Akçay F. The relationship between varicocele and semen nitric oxide concentrations. Urol Res. 2000 ; 28 (6). 357-359 (Pubitemid 32039603)
    • (2000) Urological Research , vol.28 , Issue.6 , pp. 357-359
    • Aksoy, H.1    Aksoy, Y.2    Ozbey, I.3    Altuntas, I.4    Akcay, F.5
  • 38
    • 52949119970 scopus 로고    scopus 로고
    • Impact of clinical varicocele and testis size on seminal reactive oxygen species levels in a fertile population: A prospective controlled study
    • Cocuzza M, Athayde KS, Agarwal A, et al. Impact of clinical varicocele and testis size on seminal reactive oxygen species levels in a fertile population: a prospective controlled study. Fertil Steril. 2008 ; 90 (4). 1103-1108
    • (2008) Fertil Steril , vol.90 , Issue.4 , pp. 1103-1108
    • Cocuzza, M.1    Athayde, K.S.2    Agarwal, A.3
  • 41
    • 33645292883 scopus 로고    scopus 로고
    • Increased sperm DNA damage in patients with varicocele: Relationship with seminal oxidative stress
    • Smith R, Kaune H, Parodi D, et al. Increased sperm DNA damage in patients with varicocele: relationship with seminal oxidative stress. Hum Reprod. 2006 ; 21 (4). 986-993
    • (2006) Hum Reprod , vol.21 , Issue.4 , pp. 986-993
    • Smith, R.1    Kaune, H.2    Parodi, D.3
  • 42
    • 3142701306 scopus 로고    scopus 로고
    • Testicular tissue nitric oxide and thiobarbituric acid reactive substance levels: Evaluation with respect to the pathogenesis of varicocele
    • Kisa U, Basar MM, Ferhat M, et al. Testicular tissue nitric oxide and thiobarbituric acid reactive substance levels: evaluation with respect to the pathogenesis of varicocele. Urol Res. 2004 ; 32 (3). 196-199 (Pubitemid 38915686)
    • (2004) Urological Research , vol.32 , Issue.3 , pp. 196-199
    • Kisa, U.1    Basar, M.M.2    Ferhat, M.3    Yilmaz, E.4    Basar, H.5    Caglayan, O.6    Batislam, E.7
  • 43
    • 10844255563 scopus 로고    scopus 로고
    • Testicular oxidative stress: Effects of experimental varicocele in adolescent rats
    • DOI 10.1159/000081596
    • Ozdamar AS, Soylu AG, Culha M, Ozden M, Gökalp A. Testicular oxidative stress. Effects of experimental varicocele in adolescent rats. Urol Int. 2004 ; 73 (4). 343-347 (Pubitemid 39664308)
    • (2004) Urologia Internationalis , vol.73 , Issue.4 , pp. 343-347
    • Ozdamar, A.S.1    Soylu, A.G.2    Culha, M.3    Ozden, M.4    Gokalp, A.5
  • 44
    • 77949743807 scopus 로고    scopus 로고
    • Effects of aminoguanidine on infertile varicocelized rats: A functional and morphological study
    • Alizadeh N, Abbasi M, Abolhassani F, et al. Effects of aminoguanidine on infertile varicocelized rats: a functional and morphological study. DARU. 2010 ; 18 (1). 51-55
    • (2010) DARU , vol.18 , Issue.1 , pp. 51-55
    • Alizadeh, N.1    Abbasi, M.2    Abolhassani, F.3
  • 45
    • 39449106916 scopus 로고    scopus 로고
    • The effects of nitric oxide synthase inhibitor (L-NAME) on epididymal sperm count, motility, and morphology in varicocelized rat
    • Bahmanzadeh M, Abolhassani F, Amidi F, Ejtemaiemehr S, Salehi M, Abbasi M. The effects of nitric oxide synthase inhibitor (L-NAME) on epididymal sperm count, motility, and morphology in varicocelized rat. DARU. 2008 ; 16 (1). 23-28 (Pubitemid 351270440)
    • (2008) Daru , vol.16 , Issue.1 , pp. 23-28
    • Bahmanzadeh, M.1    Abolhassani, F.2    Amidi, F.3    Ejtemaiemehr, S.H.4    Salehi, M.5    Abbasi, M.6
  • 46
    • 0345487010 scopus 로고    scopus 로고
    • Effect of aminoguanidine on the generation of superoxide anion and nitric oxide by peripheral blood granulocytes of rats with streptozotocin-induced diabetes
    • DOI 10.1016/S0009-8981(98)00130-2, PII S0009898198001302
    • Kedziora-Kornatowska KZ, Luciak M, Błaszczyk J, Pawlak W. Effect of aminoguanidine on the generation of superoxide anion and nitric oxide by peripheral blood granulocytes of rats with streptozotocin-induced diabetes. Clin Chim Acta. 1998 ; 278 (1). 45-53 (Pubitemid 28544985)
    • (1998) Clinica Chimica Acta , vol.278 , Issue.1 , pp. 45-53
    • Kedziora-Kornatowska, K.Z.1    Luciak, M.2    Blaszczyk, J.3    Pawlak, W.4
  • 47
    • 0035103524 scopus 로고    scopus 로고
    • Chromatin status in human ejaculated spermatozoa from infertile patients and relationship to seminal parameters
    • Molina J, Castaño JA, Fontes J, Mendoza N, Martinez L. Chromatin status in human ejaculated spermatozoa from infertile patients relationship to seminal parameters. Hum Reprod Update. 2000 ; 16 (3). 534-539 (Pubitemid 32218806)
    • (2001) Human Reproduction , vol.16 , Issue.3 , pp. 534-539
    • Molina, J.1    Castilla, J.A.2    Castano, J.L.3    Fontes, J.4    Mendoza, N.5    Martinez, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.