Lung cancer risk in relation to traffic-related nano/ultrafine particle-bound PAHs exposure: A preliminary probabilistic assessment

Journal of Hazardous Materials

Volumn 190, Issue 1-3, 2011, Pages 150-158

  Liao, Chung Min ^a   Chio, Chia Pin ^a   Chen, Wei Yu ^a   Ju, Yun Ru ^a   Li, Wen Hsuan ^a   Cheng, Yi Hsien ^a   Liao, Vivian Hsiu Chuan ^a   Chen, Szu Chieh ^b,c   Ling, Min Pei ^d  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Lung cancer; Nanoparticles; Particulate matter; Polycyclic aromatic hydrocarbons; Population attributable fraction; Risk assessment

Indexed keywords

ASSESSMENT PROGRAMS; ATTRIBUTABLE FRACTION; BENZO(A)PYRENE; DEPOSITION FRACTIONS; DOSE RESPONSE; HUMAN LUNG; HUMAN RESPIRATORY TRACT MODELS; INCIDENCE RATE; INHALATION EXPOSURE; LUNG CANCER; PARTICULATE MATTER; PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS; POLYCYCLIC AROMATICS; POPULATION ATTRIBUTABLE FRACTION; POPULATION LEVELS; PROBABILISTIC ASSESSMENTS; PROBABILISTIC RISK ASSESSMENT; RISK FACTORS; TRAFFIC-RELATED; ULTRAFINE;

AROMATIC COMPOUNDS; BIOLOGICAL ORGANS; DISEASES; HYDROCARBONS; PARTICLE SIZE ANALYSIS; PHYSIOLOGICAL MODELS; POLYCYCLIC AROMATIC HYDROCARBONS; POPULATION STATISTICS; RATING; RISK PERCEPTION;

RISK ASSESSMENT;

BENZO[A]PYRENE; POLYCYCLIC AROMATIC HYDROCARBON;

CANCER; CARCINOGEN; HEALTH RISK; PAH; POLLUTION EXPOSURE; PROBABILITY; PUBLIC HEALTH; RISK ASSESSMENT; SIZE DISTRIBUTION;

ARTICLE; CANCER INCIDENCE; CANCER RISK; ENVIRONMENTAL EXPOSURE; HUMAN; LUNG CANCER; PARTICLE SIZE; QUANTITATIVE ANALYSIS; RISK ASSESSMENT;

ENVIRONMENTAL EXPOSURE; HUMANS; INCIDENCE; LUNG NEOPLASMS; MODELS, THEORETICAL; NANOPARTICLES; POLYCYCLIC HYDROCARBONS, AROMATIC; RISK; RISK ASSESSMENT; VEHICLE EMISSIONS;

TAIWAN;

EID: 79956141417     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2011.03.017     Document Type: Article

References (47)

1. Thyssen J., Althoff J., Kimmerle G., Mohr U. Inhalation studies with benzo alpha pyrene in Syrian golden-hamsters. J. Natl. Cancer Inst. 1981, 66:575-577.
2. Deutsch-Wenzel R.P., Brune H., Grimmer G. Experimental studies on the carcinogenicity of five nitrogen containing polycyclic aromatic compounds directly injected into rat lungs. Cancer Lett. 1983, 20:97-101.
3. Boffetta P., Jourenkova N., Gustavsson P. Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons. Cancer Causes Control 1997, 8:444-472.
4. Armstrong B., Hutchinson E., Unwin J., Fletcher T. Lung cancer risk after exposure to polycyclic aromatic hydrocarbons: a review and meta-analysis. Environ. Health Perspect. 2004, 112:970-978.
5. Cheng J.P., Yuan T., Wu Q., Zhao W.C., Xie H.Y., Ma Y.G., Wang W.H. PM10-bound polycyclic aromatic hydrocarbons (PAHs) and cancer risk estimation in the atmosphere surrounding an industrial area of Shanghai, China. Water Air Soil Pollut. 2007, 183:437-446.
6. Lin C.C., Chen S.J., Huang K.L., Lee W.J., Lin W.Y., Tsai J.H., Chaung H.C. PAHs, PAH-induced carcinogenic potency, and particle-extract-induced cytotoxicity of traffic-related nano/ultrafine particles. Environ. Sci. Technol. 2008, 42:4229-4235.
7. Ravindra K., Wauters E., Van Grieken R. Variation in particulate PAHs levels and their relation with the transboundary movement of the air masses. Sci. Total Environ. 2008, 396:100-110.
8. Armstrong B.G., Gibbs G. Exposure-response relationship between lung cancer and polycyclic aromatic hydrocarbons (PAHs). Occup. Environ. Med. 2009, 66:740-746.
9. Kawanaka Y., Tsuchiya Y., Yun S.J., Sakamoto K. Size distributions of polycyclic aromatic hydrocarbons in the atmosphere and estimation of the contribution of ultrafine particles to their lung deposition. Environ. Sci. Technol. 2009, 43:6851-6856.
10. Zhang Y., Tao S., Shen H., Ma J. Inhalation exposure to ambient polycyclic aromatic hydrocarbons and lung cancer risk of Chinese population. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:21063-21067.
11. Taiwan Department of Health (Taiwan DOH) Cancer Registry Annual Report 2007, Taiwan DOH, Taiwan.
12. Yang H.H., Lai S.O., Hsieh L.T., Hsueh H.J., Chi T.W. Profiles of PAH emission from steel and iron industries. Chemosphere 2002, 48:1061-1074.
13. Yang H.H., Hsieh L.T., Liu H.C., Mi H.H. Polycyclic aromatic hydrocarbon emissions from motorcycles. Atmos. Environ. 2005, 39:17-25.
14. Tsai P.J., Shih T.S., Chen H.L., Lee W.J., Lai C.H., Liou S.H. Assessing and predicting the exposures of polycyclic aromatic hydrocarbons (PAHs) and their carcinogenic potencies from vehicle engine exhausts to highway toll station workers. Atmos. Environ. 2004, 38:333-343.
15. Fang G.C., Chang K.F., Lu C.S., Bai H.L. Estimation of PAHs dry deposition and BaP toxic equivalency factors (TEFs) study at Urban, Industry Park and rural sampling sites in central Taiwan, Taichung. Chemosphere 2004, 55:787-796.
16. Fang G.C., Wu Y.S., Chen M.H., Ho T.T., Huang S.H., Rau J.Y. Polycyclic aromatic hydrocarbons study in Taichung, Taiwan, during 2002-2003. Atmos. Environ. 2004, 38:3385-3391.
17. Fang G.C., Wu Y.S., Fu P.P.C., Yang I.L., Chen M.H. Polycyclic aromatic hydrocarbons in the ambient air of suburban and industrial regions of central Taiwan. Chemosphere 2004, 54:443-452.
18. Colvin V.L. The potential environmental impact of engineered nanomaterials. Nat. Biotechnol. 2003, 21:1166-1170.
19. Oberdorster G., Oberdorster E., Oberdorster J., Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 2005, 113:823-839.
20. Nel A., Xia T., Madler L., Li N. Toxic potential of materials at the nanolevel. Science 2006, 311:622-627.
21. Mills N.L., Donaldson K., Hadoke P.W., Boon N.A., MacNee W., Cassee F.R., Sandstrom T., Blomberg A., Newby D.E. Adverse cardiovascular effects of air pollution. Nat. Clin. Pract. Cardiovasc. Med. 2009, 6:36-44.
22. Huh D., Matthews B.D., Mammoto A., Montoya-Zavala M., Hsin H.Y., Ingber D.E. Reconstituting organ-level lung functions on a chip. Science 2010, 328:1662-1668.
23. Bocskay K.A., Tang D., Orjuela M.A., Liu X., Warburton D.P., Perera F.P. Chromosomal aberrations in cord blood are associated with prenatal exposure to carcinogenic polycyclic aromatic hydrocarbons. Cancer Epidemiol. Biomarkers Prev. 2005, 14:506-511.
24. Ezzati M., Vander Hoom S., Rodgers A., Lopez A.D., Mathers C.D., Murray C.J.L. Comparative Risk Assessment Collaborating Group, Estimates of global and regional potential health gains from reducing multiple major risk factors. Lancet 2003, 362:271-280.
25. Lopez A.D., Mathers C.D., Ezzati M., Jamison D.T., Murray C.J.L. Global and regional burden of disease and risk factors 2001 systematic analysis of population health data. Lancet 2006, 367:1747-1757.
26. Menzler S., Piller G., Gruson M., Rosario A.S., Wichrnann H.E., Kreienbrock L. Population attributable fraction for lung cancer due to residential radon in Switzerland and Germany. Health Phys. 2008, 95:179-189.
27. ICRP Human Respiratory Tract Model for Radiological Protection, a Report of a Task Group of the International Commission on Radiological Protection, ICRP Publication No. 66 1994, Pergamon Press, New York.
28. Lazaridis M., Broday D.M., Hov Ø.P.G. Georgopoulos, Integrated exposure and dose modeling and analysis system. 3. Deposition of inhaled particles in the human respiratory tract. Environ. Sci. Technol. 2001, 35:3727-3734.
29. Chen J.W., Liao C.M., Chen S.C. Compartmental human respiratory tract modeling of airborne dust exposure from feeding in swine buildings. J. Air Waste Manage. Assoc. 2004, 54:331-341.
30. Dennison J.E., Anderson M.E., Clewell H.J., Yang R.S.H. Development of a physiologically based pharmacokinetic model for volatile fractions of gasoline using chemical lumping analysis. Environ. Sci. Technol. 2004, 38:5674-5681.
31. Clewell H.J., Gentry P.R., Kester J.E., Anderson M.E. Evaluation of physiologically based pharmacokinetic models in risk assessment: an example with perchloroethylene. Crit. Rev. Toxicol. 2005, 35:413-433.
32. Liao C.M., Chen S.C. A probabilistic modeling approach to assess human inhalation exposure risks to airborne aflatoxin B1 (AFB1). Atmos. Environ. 2005, 39:6481-6490.
33. Liao C.M., Chen J.W., Huang S.J. Size-dependent PM10 indoor/outdoor/personal relationships for a wind-induced naturally ventilated airspace. Atmos. Environ. 2003, 37:3065-3075.
34. Andersen M.E., Clewell H.J., Gargas M.L., Smith F.A., Reitz R.H. Physiologically based pharmacokinetics and the risk assessment process for methylene chloride. Toxicol. Appl. Pharmacol. 1987, 87:185-205.
35. Mielke H., Gundert A., Abraham K., Gundert-Remy U. Acute inhalative exposure assessment: derivation of guideline levels with special regard to sensitive subpopulations and time scaling. Toxicology 2005, 214:256-267.
36. Poulin P., Krishnan K. A biologically-based algorithm for predicting human tissue-blood partition coefficients of organic chemicals. Hum. Exp. Toxicol. 1995, 14:273-280.
37. Poulin P., Theil F.P. Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution. J. Pharm. Sci. 2002, 91:129-156.
38. Ramsey J.C., Andersen M.E. A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicol. Appl. Pharmacol. 1984, 73:159-175.
39. Goldstein L.S. To BaP or not to BaP? That is the question. Environ. Health Perspect. 2001, 109:A356-A357.
40. Nisbet T.I.C., LaGoy P.K. Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons (PAHs). Regul. Toxicol. Pharmacol. 1992, 16:290-300.
41. Mirabelli D. An improved estimate of the quantitative relationship between polycyclic hydrocarbons and lung cancer. Occup. Environ. Med. 2009, 66:716-717.
42. Russell A.G., Brunekreef B. A focus on particulate matter and health. Environ. Sci. Technol. 2009, 43:4620-4625.
43. Bae S., Pan X.C., Kim S.Y., Park K., Kim Y.H., Kim H., Hong Y.C. Exposures to particulate matter and polycyclic aromatic hydrocarbons and oxidative stress in schoolchildren. Environ. Health Perspect. 2010, 118:579-583.
44. Mordukhovich I., Possner P., Terry M.B., Santella R., Zhang Y.J., Hibshoosh H., Memeo L., Mansukhani M., Long C.M., Garbowski G., Agrawal M., Gaudet M.M., Steck S.E., Sagiv S.K., Eng S.M., Teitelbaum S.L., Neugut A.I., Conway-Dorsey K., Gammon M.D. Associations between polycyclic aromatic hydrocarbon-related exposures and p53 mutations in breast tumors. Environ. Health Perspect. 2010, 118:511-518.
45. Tao S., Zhang D., Lu Y., Li L., Ding J., Yang Y., Yang Y., Wang X., Liu W., Xing B. Mobility of polycyclic aromatic hydrocarbons in the gastrointestinal tract assessed using an in vitro digestion model with sorption rectification. Environ. Sci. Technol. 2010, 44:5608-5612.
46. ICRP Basic Anatomical and Physiological Data for Use in Radiological Protection: Reference Values, ICRP Publication No. 89 2003, Pergamon Press, New York.
47. Wiersma D.A., Roth R.A. The prediction of benzo[a]pyrene clearance by rat liver and lung from enzyme kinetic data. Mol. Pharmacol. 1983, 24:300-308.