Surface mass spectrometry of two component drug-polymer systems: Novel chromatographic separation method using gentle-secondary ion mass spectrometry (G-SIMS)

Analytical Chemistry

Volumn 83, Issue 10, 2011, Pages 3627-3631

  Ogaki, Ryosuke ^a   Gilmore, Ian S ^a,b   Alexander, Morgan R ^a   Green, Felicia M ^b   Davies, Martyn C ^a   Lee, Joanna L S ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NATIONAL PHYSICAL LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS TIME; CHROMATOGRAPHIC SEPARATIONS; CONTROL PARAMETERS; DRUG MOLECULES; FLIGHT TIME; FRAGMENTATION BEHAVIOR; G INDICES; HIGH DEFINITION; INSTRUMENT DESIGNS; ION MASS SPECTROMETRY; ION MOBILITY; MASS SPECTRA; MATERIAL SURFACE; MATRIX POLYMERS; MULTICOMPONENTS; SEPARATION METHODS; SOURCE CONDITIONS; SPATIAL RESOLUTION; TIME OF FLIGHT SECONDARY ION MASS SPECTROMETRY; TOF SIMS; TWO-COMPONENT;

GAS CHROMATOGRAPHY; ION CHROMATOGRAPHY; ION SOURCES; SECONDARY EMISSION; SECONDARY ION MASS SPECTROMETRY; SPECTROMETRY;

IONS;

BUPIVACAINE; CODEINE; DRUG; LACTIC ACID; POLYLACTIC ACID; POLYMER;

ARTICLE; CHEMISTRY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METHODOLOGY;

BUPIVACAINE; CODEINE; LACTIC ACID; PHARMACEUTICAL PREPARATIONS; POLYMERS; SPECTROMETRY, MASS, SECONDARY ION;

EID: 79956139582     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac200347a     Document Type: Article

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