The MELD score in patients awaiting liver transplant: Strengths and weaknesses

Journal of Hepatology

Volumn 54, Issue 6, 2011, Pages 1297-1306

  Bernardi, Mauro ^a,b   Gitto, Stefano ^a   Biselli, Maurizio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Complications of cirrhosis; End stage liver disease; Hepatocellular carcinoma; Liver transplantation; MELD score; Organ allocation policy

Indexed keywords

BILIRUBIN; CREATININE; PROTHROMBIN;

ACUTE KIDNEY FAILURE; ACUTE LIVER FAILURE; ARTICLE; ASCITES; BACTERIAL INFECTION; BILIRUBIN BLOOD LEVEL; CHRONIC LIVER DISEASE; CHRONIC LIVER FAILURE; CLINICAL ASSESSMENT TOOL; COHORT ANALYSIS; CREATININE BLOOD LEVEL; DIAGNOSTIC ACCURACY; DISEASE SEVERITY; END STAGE LIVER DISEASE; ESOPHAGUS VARICES BLEEDING; FAMILIAL AMYLOIDOSIS; GASTROINTESTINAL HEMORRHAGE; GENDER; GRAFT RECIPIENT; HEALTH CARE POLICY; HEPATIC ENCEPHALOPATHY; HEPATITIS B; HEPATITIS C; HEPATOPULMONARY SYNDROME; HEPATORENAL SYNDROME; HOSPITAL ADMISSION; HUMAN; HYPONATREMIA; INTERNATIONAL NORMALIZED RATIO; LABORATORY TEST; LIVER; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MALNUTRITION; MELD SCORE; PORTAL HYPERTENSION; PORTOPULMONARY HYPERTENSION; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; PROTHROMBIN TIME; RATING SCALE; RISK ASSESSMENT; SCORING SYSTEM; SURGICAL MORTALITY; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR VOLUME;

EID: 79956135189     PISSN: 01688278     EISSN: 01688278     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.11.008     Document Type: Note

References (103)

1. R.M. Merion, D.E. Schaubel, D.M. Dykstra, R.B. Freeman, F.K. Port, and R.A. Wolfe The survival benefit of liver transplantation Am J Transplant 5 2005 307 313 (Pubitemid 40179517)
2. R.B. Freeman Jr., and E.B. Edwards Liver transplant waiting time does not correlate with waiting list mortality: implications for liver allocation policy Liver Transpl 6 2000 543 552
3. M.R. Lucey, K.A. Brown, G.T. Everson, J.J. Fung, R. Gish, and E.B. Keeffe Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases Liver Transpl Surg 3 1997 628 637 (Pubitemid 27498478)
4. Organ Procurement and Transplantation Network-HRSA. Final rule with comment period. Fed Regist 1998;63:16296-16338.
5. C.G. Child, and J.G. Turcotte Surgery and portal hypertension Major Probl Clin Surg 1 1964 1 85
6. R.N. Pugh, I.M. Murray-Lyon, J.L. Dawson, M.C. Pietroni, and R. Williams Transection of the oesophagus for bleeding oesophageal varices Br J Surg 60 1973 646 649
7. M. Malinchoc, P.S. Kamath, F.D. Gordon, C.J. Peine, J. Rank, and P.C. ter Borg A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts Hepatology 31 2000 864 871 (Pubitemid 30169932)
8. P.S. Kamath, R.H. Wiesner, M. Malinchoc, W. Kremers, T.M. Therneau, and C.L. Kosberg A model to predict survival in patients with end-stage liver disease Hepatology 33 2001 464 470 (Pubitemid 32119037)
9. R. Wiesner, E. Edwards, R. Freeman, A. Harper, R. Kim, and P. Kamath Model for end-stage liver disease (MELD) and allocation of donor livers Gastroenterology 124 2003 91 96 (Pubitemid 36055342)
10. P.S. Kamath, and W.R. Kim The Model for End-Stage Liver Disease (MELD) Hepatology 45 2007 797 805 (Pubitemid 46450631)
11. B. Brandsaeter, U. Broomé, H. Isoniemi, S. Friman, B. Hansen, and E. Schrumpf Liver transplantation for primary sclerosing cholangitis in the Nordic countries: outcome after acceptance to the waiting list Liver Transpl 9 2003 961 969 (Pubitemid 37098845)
12. A. Said, J. Williams, J. Holden, P. Remington, R. Gangnon, and A. Musat Model for end stage liver disease score predicts mortality across a broad spectrum of liver disease J Hepatol 40 2004 897 903 (Pubitemid 38670122)
13. F. Botta, E. Giannini, P. Romagnoli, A. Fasoli, F. Malfatti, and B. Chiarbonello MELD scoring system is useful for predicting prognosis in patients with liver cirrhosis and is correlated with residual liver function: a European study Gut 52 2003 134 139 (Pubitemid 36020780)
14. R.B. Freeman, R.H. Wiesner, E. Edwards, A. Harper, R. Merion, and R. Wolfe Results of the first year of the new liver allocation plan Liver Transpl 10 2004 7 15 (Pubitemid 38885887)
15. F. Kanwal, G.S. Dulai, B.M. Spiegel, H.F. Yee, and I.M. Gralnek A comparison of liver transplantation outcomes in the pre- vs. post-MELD eras Aliment Pharmacol Ther 21 2005 169 177 (Pubitemid 40222970)
16. C.L. Berg, D.E. Steffick, E.B. Edwards, J.K. Heimbach, J.C. Magee, and W.K. Washburn Liver and intestine transplantation in the United States 1998-2007 Am J Transplant 9 2009 907 931
17. R.S. Brown Jr., and J.R. Lake The survival impact of liver transplantation in the MELD era, and the future for organ allocation and distribution Am J Transplant 5 2005 203 204 (Pubitemid 40179505)
18. M.A. Fink, P.W. Angus, P.J. Gow, S.R. Berry, B.Z. Wang, and V. Muralidharan Liver transplant recipient selection: MELD vs. clinical judgment Liver Transpl 11 2005 621 626 (Pubitemid 40872899)
19. N.M. Desai, K.C. Mange, M.D. Crawford, P.L. Abt, A.M. Frank, and J.W. Markmann Predicting outcome after liver transplantation: utility of the model for end-stage liver disease and a newly derived discrimination function Transplantation 77 2004 99 106 (Pubitemid 38116879)
20. M. Jacob, L.P. Copley, J.D. Lewsey, A. Gimson, G.J. Toogood, and M. Rela Pretransplant MELD score and post liver transplantation survival in the UK and Ireland Liver Transpl 10 2004 903 907 (Pubitemid 38979261)
21. T.I. Huo, S.D. Lee, and H.C. Lin Selecting an optimal prognostic system for liver cirrhosis: the model for end-stage liver disease and beyond Liver Int 28 2008 606 613
22. F. Durand, and D. Valla Assessment of prognosis of cirrhosis Semin Liver Dis 28 2008 110 122 (Pubitemid 351326537)
23. G. D'Amico, G. Garcia-Tsao, and L. Pagliaro Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies J Hepatol 44 2006 217 231 (Pubitemid 41772537)
24. R. Adam, P. McMaster, J.G. O'Grady, D. Castaing, J.L. Klempnauer, and N. Jamieson Evolution of liver transplantation in Europe: report of the European Liver Transplant Registry Liver Transpl 9 2003 1231 1243 (Pubitemid 37536793)
25. V. Mazzaferro, E. Regalia, R. Doci, S. Andreola, A. Pulvirenti, and F. Bozzetti Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis N Engl J Med 334 1996 693 699 (Pubitemid 26079803)
26. J.P. Duffy, A. Vardanian, E. Benjamin, M. Watson, D.G. Farmer, and R.M. Ghobrial Liver transplantation criteria for hepatocellular carcinoma should be expanded: a 22-year experience with 467 patients at UCLA Ann Surg 246 2007 502 511
27. S. Cheng, R. Freeman, and J. Wong Predicting the probability of progression-free survival in patients with small hepatocellular carcinoma Liver Transpl 8 2002 323 328 (Pubitemid 34467364)
28. P. Sharma, V. Balan, J.L. Hernandez, A.M. Harper, E.B. Edwards, and H. Rodriguez-Luna Liver transplantation for hepatocellular carcinoma: the MELD impact Liver Transpl 10 2004 36 41 (Pubitemid 38885890)
29. T.I. Huo, J.C. Wu, H.C. Lin, F.Y. Lee, M.C. Hou, and Y.H. Huang Determination of the optimal Model for End-Stage Liver Disease score in patients with small hepatocellular carcinoma undergoing loco-regional therapy Liver Transpl 10 2004 1507 1513
30. F.Y. Yao, N.M. Bass, B. Nikolai, R. Merriman, T.J. Davern, and R. Kerlan A follow-up analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implication for the current organ allocation policy Liver Transpl 9 2003 684 692 (Pubitemid 36874454)
31. M. Sala, M. Varela, and J. Bruix Selection of candidates with HCC for transplantation in the MELD era Liver Transpl 10 2004 S4 S9
32. R.B. Freeman Liver allocation for HCC: a moving target Liver Transpl 10 2004 49 51 (Pubitemid 38885892)
33. K. Roayaie, and S. Feng Allocation policy for hepatocellular carcinoma in the MELD era: room for improvement? Liver Transpl 13 S2 2007 S36 S43
34. M. Ravaioli, G.L. Grazi, G. Ballardini, G. Cavrini, G. Ercolani, and M. Cescon Liver transplantation with the Meld system: a prospective study from a single European center Am J Transplant 6 2006 1572 1577 (Pubitemid 43945796)
35. R.B. Freeman, E.B. Edwards, and A.M. Harper Comparison of liver transplant waiting list removal rates among patients with chronic and malignant liver diseases Am J Transplant 6 2006 1416 1421 (Pubitemid 44030324)
36. R. Rodrguez-Roisin, and M.J. Krowka Hepatopulmonary syndrome - a liver-induced lung vascular disorder N Engl J Med 358 2008 2378 2387
37. M. Ashfaq, S. Chinnakotla, L. Rogers, K. Ausloos, S. Saadeh, and G.B. Klintmalm The impact of treatment of portopulmonary hypertension on survival following liver transplantation Am J Transpl 7 2007 1 7
38. M. Moini, P. Mistry, and M.L. Schilsky Liver transplantation for inherited metabolic disorders of the liver Curr Opin Organ Transplant 15 2010 269 276
39. R.B. Freeman Jr., R.G. Gish, A. Harper, G.L. Davis, J. Vierling, and L. Lieblein Model for end-stage liver disease (MELD) exception guidelines: results and recommendations from the MELD Exception Study Group and Conference (MESSAGE) for the approval of patients who need liver transplantation with diseases not considered by the standard MELD formula Liver Transpl 12 2006 S128 S136
40. J. Neuberger, A. Gimson, M. Davies, M. Akyol, J. O'Grady, and A. Burroughs Selection of patients for liver transplantation and allocation of donated livers in the UK Gut 57 2008 252 257 (Pubitemid 351158055)
41. M. Ravaioli, M. Masetti, A. Dazzi, A. Romano, M. Spaggiari, and G.L. Grazi Model for End-Stage Liver Disease (MELD) system to allocate and to share livers: experience of two Italian centers Transplant Proc 40 2008 1814 1815
42. R.B. Freeman Jr. Model for End-Stage Liver Disease (MELD) for liver allocation: a 5-year score card Hepatology 47 2008 1052 1057 (Pubitemid 351449696)
43. T.I. Huo, H.C. Lin, F.Y. Lee, M.C. Hou, P.C. Lee, and J.C. Wu Occurrence of cirrhosis-related complications is a time dependent prognostic predictor independent of baseline model for endstage liver disease score Liver Int 26 2006 55 61
44. H.Y. Yoo, D. Edwin, and P.J. Thuluvath Relationship of the model for end-stage liver disease (MELD) scale to hepatic encephalopathy, as defined by electroencephalography and neuropsychometric testing, and ascites Am J Gastroenterol 98 2003 1395 1399 (Pubitemid 36741540)
45. P. Ginés, T. Berl, M. Bernardi, D.G. Bichet, G. Hamon, and W. Jiménez Hyponatremia in cirrhosis: from pathogenesis to treatment Hepatology 28 1998 851 864 (Pubitemid 28405440)
46. A. Gins, A. Escorsell, P. Gins, J. Saló, W. Jiménez, and L. Inglada Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites Gastroenterology 105 1993 229 236 (Pubitemid 23234041)
47. P. Gins, and M. Guevara Hyponatremia in cirrhosis: pathogenesis, clinical significance, and management Hepatology 48 2008 1002 1010
48. P. Angeli, F. Wong, H. Watson, and P. Gins CAPPS investigators. Hyponatremia in cirrhosis: results of a patient population survey Hepatology 44 2006 1535 1542 (Pubitemid 44953659)
49. D.M. Heuman, S.G. Abou-Assi, A. Habib, L.M. Williams, R.T. Stravitz, and A.J. Sanyal Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death Hepatology 40 2004 802 810 (Pubitemid 39288112)
50. A.E. Ruf, W.K. Kremers, L.L. Chavez, V.I. Descalzi, L.G. Podesta, and F.G. Villamil Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone Liver Transpl 11 2005 336 343 (Pubitemid 40458408)
51. S.W. Biggins, H.J. Rodriguez, P. Bacchetti, N.M. Bass, J.P. Roberts, and N.A. Terrault Serum sodium predicts mortality in patients listed for liver transplantation Hepatology 41 2005 32 39 (Pubitemid 40066380)
52. S.W. Biggins, W.R. Kim, N.A. Terrault, S. Saab, V. Balan, and T. Schiano Evidence-based incorporation of serum sodium concentration into MELD Gastroenterology 130 2006 1652 1660 (Pubitemid 43668830)
53. M.C. Londoño, A. Cárdenas, and M. Guevara MELDscore and serum sodium in the prediction of survival of patients with cirrhosis awaiting liver transplantation Gut 56 2007 1283 1290 (Pubitemid 47300431)
54. A. O'Brien, and R. Williams Nutrition in end-stage liver disease: principles and practice Gastroenterology 134 2008 1729 1740 (Pubitemid 351615408)
55. E. Cabre, and M.A. Gassul Nutrition in chronic liver disease and liver transplantation Curr Opin Nutr Metab Care 1 1998 423 430 (Pubitemid 128539501)
56. J. Sam, and G.C. Nguyen Protein-calorie malnutrition as a prognostic indicator of mortality among patients hospitalized with cirrhosis and portal hypertension Liver Int 29 2009 1396 1402
57. M. Merli, O. Riggio, and L. Dally Does malnutrition affect survival in cirrhosis? PINC (Policentrica Italiana Nutrizione Cirrosi) Hepatology 23 1996 1041 1046
58. F. Alberino, A. Gatta, P. Amodio, C. Merkel, L. Di Pascoli, and G. Boffo Nutrition and survival in patients with liver cirrhosis Nutrition 17 2001 445 450 (Pubitemid 32505665)
59. F. Gunsar, M.L. Raimondo, S. Jones, N. Terreni, C. Wong, and D. Patch Nutritional status and prognosis in cirrhotic patients Aliment Pharmacol Ther 24 2006 563 572 (Pubitemid 44127837)
60. M.R. Alvares-da-Silva, and T. Reverbel da Silveira Comparison between handgrip strength, subjective global assessment, and prognostic nutritional index in assessing malnutrition and predicting clinical outcome in cirrhotic outpatients Nutrition 21 2005 113 117 (Pubitemid 40255717)
61. C. Alessandria, O. Ozdogan, M. Guevara, T. Restuccia, W. Jiménez, and V. Arroyo MELD score and clinical type predict prognosis in hepatorenal syndrome: relevance to liver transplantation Hepatology 41 2005 1282 1289 (Pubitemid 40770280)
62. K. Rifai, A. Kribben, G. Gerken, S. Haag, S. Herget-Rosenthal, and U. Treichel J Hepatol 52 2010 S3
63. R. Bañares, F. Nevens, F.S. Larsen, R. Jalan, A. Albillos, and M. Dollinger Extracorporeal liver support with the Molecular Adsorbent Recirculating System (MARS) in patients with acute-on-chronic liver failure (AOCLF). The RELIEF trial J Hepatol 52 2010 S459 S460
64. B. Carpentier, A. Gautier, and C. Legallais Artificial and bioartificial liver devices: present and future Gut 58 2009 1690 1702
65. B. Angermayr, A. Luca, F. König, G. Bertolini, M. Ploner, and B. Gridelli Aetiology of cirrhosis of the liver has an impact on survival predicted by the model of end-stage liver disease score Eur J Clin Invest 39 2009 65 71
66. M.R. Lucey, D.E. Schaubel, M.K. Guidinger, S. Tome, and R.M. Merion Effect of alcoholic liver disease and hepatitis C infection on waiting list and posttransplant mortality and transplant survival benefit Hepatology 50 2009 400 406
67. C.A. Moylan, C.W. Brady, J.L. Johnson, A.D. Smith, J.E. Tuttle-Newhall, and A.J. Muir Disparities in liver transplantation before and after introduction of the MELD score JAMA 300 2008 2371 2378
68. E. Cholongitas, L. Marelli, and A. Kerry Female liver transplantation recipients with the same GFR as male recipients have lower MELD scores: a systematic bias Am J Transplant 7 2007 685 692 (Pubitemid 46376449)
69. A. Flodén, M. Castedal, S. Friman, M. Olausson, and L. Backman MELD score patients accepted for liver transplantation 1994 to 2004 Transplant Proc 38 2006 2673 2674 (Pubitemid 44693647)
70. E. Cholongitas, L. Marelli, V. Shusang, M. Senzolo, and K. Rolles A systematic review of the performance of the model for end-stage liver disease (MELD) in the setting of liver transplantation Liver Transpl 12 2006 1049 1061 (Pubitemid 44063778)
71. D. Gotthardt, K.H. Weiss, M. Baumgärtner, A. Zahn, W. Stremmel, and J. Schmidt BMC Gastroenterol 9 2009 72
72. D.S. Sherman, D.N. Fish, and I. Teitelbaum Assessing renal function in cirrhotic patients: problems and pitfalls Am J Kidney Dis 41 2003 269 278 (Pubitemid 36152445)
73. D.W. Cockcroft, and M.H. Gault Prediction of creatinine clearance from serum creatinine Nephron 16 1976 31 41
74. A.S. Levey, J.P. Bosch, J.B. Lewis, T. Greene, N. Rogers, and D. Roth A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group Ann Int Med 130 1999 461 470 (Pubitemid 29135798)
75. C. Francoz, D. Pri, W. AbdelRazek, R. Moreau, A. Mandot, and J. Belghiti Inaccuracies of creatinine and creatinine-based equations in candidates for liver transplantation with low creatinine: impact on the Model for End-stage Liver Disease score Liver Transpl 16 2010 1169 1177
76. E. Cholongitas, L. Marelli, A. Kerry, M. Senzolo, D.W. Goodier, and D. Nair Different methods of creatinine measurement significantly affect MELD scores Liver Transpl 13 2007 523 529 (Pubitemid 46605854)
77. W.V. Dorwart Bilirubin interference in kinetic creatinine determination Clin Chem 25 1979 196 197
78. W.G. Miller, G.L. Myers, E.R. Ashwood, A.A. Killeen, E. Wang, and L.M. Thienpont Creatinine measurement: state of the art in accuracy and interlaboratory harmonization Arch Pathol Lab Med 129 2005 297 304 (Pubitemid 40343981)
79. L.A. Stevens, J. Coresh, T. Greene, and A.S. Levey Assessing kidney function measured and estimated glomerular filtration rate N Engl J Med 354 2006 2473 2483 (Pubitemid 43855050)
80. N.L. Proulx, A. Akbari, A.X. Garg, A. Rostom, J. Jaffey, and H.D. Clark Measured creatinine clearance from timed urine collections substantially overestimates glomerular filtration rate in patients with liver cirrhosis: a systematic review and individual patient meta-analysis Nephrol Dial Transplant 20 2005 1617 1622 (Pubitemid 41418585)
81. P. Sharma, D.E. Schaubel, C.S. Sima, R.M. Merion, and A.S. Lok Re-weighting the model for end-stage liver disease score components Gastroenterology 135 2008 1575 1581
82. T.I. Huo, C.Y. Hsu, H.C. Lin, P.C. Lee, J.Y. Lee, and F.Y. Lee Selecting an optimal cutoff value for creatinine in the model for end-stage liver disease equation Clin Transplant 24 2010 157 163
83. X. Xiol, P. Gines, L. Castells, J. Twose, A. Ribalta, and X. Fuentes-Arderiu Clinically relevant differences in the model for end-stage liver disease and model for end-stage liver disease-sodium scores determined at three university-based laboratories of the same area Liver Transpl 15 2009 300 305
84. A. Tripodi, and P.M. Mannucci Abnormalities of hemostasis in chronic liver disease: reappraisal of their clinical significance and need for clinical and laboratory research J Hepatol 46 2007 727 733 (Pubitemid 46400157)
85. A.M.P.H. Van Den Besselaar, L. Poller, and A. Tripodi World Health Organization (WHO) guidelines for thromboplastins and plasma used to control oral anticoagulant therapy WHO Techn Rep Ser 889 1999 64 93
86. A. Tripodi, V. Chantarangkul, M. Primignani, F. Fabris, A. Dell'Era, and C. Sei The international normalized ratio calibrated for cirrhosis (INR(liver)) normalizes prothrombin time results for model for end-stage liver disease calculation Hepatology 46 2007 520 527 (Pubitemid 47344788)
87. L. Bellest, V. Eschwege, R. Poupon, O. Chazouillres, and A. Robert A modified international normalized ratio as an effective way of prothrombin time standardization in hepatology Hepatology 46 2007 528 534 (Pubitemid 47344789)
88. J.F. Trotter, J. Olson, J. Lefkowitz, A.D. Smith, R. Arjal, and J. Kenison Changes in international normalized ratio (INR) and model for endstage liver disease (MELD) based on selection of clinical laboratory Am J Transplant 7 2007 1624 1628 (Pubitemid 46776260)
89. S.H. Caldwell, M. Hoffman, T. Lisman, B.G. Macik, P.G. Northup, and K.R. Reddy Coagulation disorders and hemostasis in liver disease: pathophysiology and critical assessment of current management Hepatology 44 2006 1039 1046 (Pubitemid 46489567)
90. T. Lisman, Y. van Leeuwen, J. Adelmeijer, I.T. Pereboom, E.B. Haagsma, and A.P. van den Berg Interlaboratory variability in assessment of the model of end-stage liver disease score Liver Int 28 2008 1344 1351
91. W.R. Kim, S.W. Biggins, W.K. Kremers, R.H. Wiesner, P.S. Kamath, and J.T. Benson Hyponatremia and mortality among patients on the liver-transplant waiting list N Engl J Med 359 2008 1018 1026
92. A. Luca, B. Angermayr, G. Bertolini, F. Koenig, G. Vizzini, and M. Ploner An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis Liver Transpl 13 2007 1174 1180 (Pubitemid 47307228)
93. M.F. Levy, P.S. Somasundar, L.W. Jennings, G.J. Jung, E.P. Molmenti, and C.G. Fasola The elderly liver transplant recipient: a call for caution Ann Surg 233 2001 107 113 (Pubitemid 32042780)
94. N. Kemmer, K. Safdar, T.E. Kaiser, V. Zacharias, and G.W. Neff Liver transplantation trends for older recipients: regional and ethnic variations Transplantation 86 2008 104 107
95. K.M. Barber, S. Pioli, and J.E. Blackwell Development of a UK score for patients with end-stage liver disease Hepatology 46 2007 510A
96. T.I. Huo, Y.W. Wang, Y.Y. Yang, H.C. Lin, P.C. Lee, and M.C. Hou Model for end-stage liver disease score to serum sodium ratio index as a prognostic predictor and its correlation with portal pressure in patients with liver cirrhosis Liver Int 27 2007 498 506 (Pubitemid 46534572)
97. M. Somsouk, J. Guy, S.W. Biggins, E. Vittinghoff, M.A. Kohn, and J.M. Inadomi Ascites improves upon plus serum sodium model for end-stage liver disease (MELD) for predicting mortality in patients with advanced liver disease Aliment Pharmacol Ther 30 2009 741 748
98. R.M. Merion, R.A. Wolfe, D.M. Dykstra, A.B. Leichtman, B. Gillespie, and P.J. Held Longitudinal assessment of mortality risk among candidates for liver transplantation Liver Transpl 9 2003 12 18 (Pubitemid 36104909)
99. T.I. Huo, J.C. Wu, H.C. Lin, F.Y. Lee, M.C. Hou, and P.C. Lee Evaluation of the increase in model for end-stage liver disease (DeltaMELD) score over time as a prognostic predictor in patients with advanced cirrhosis: risk factor analysis and comparison with initial MELD and Child-Turcotte-Pugh score J Hepatol 42 2005 826 832
100. K. Bambha, W.R. Kim, W.K. Kremers, T.M. Therneau, P.S. Kamath, and R. Wiesner Predicting survival among patients listed for liver transplantation: an assessment of serial MELD measurements Am J Transplant 4 2004 1798 1804 (Pubitemid 39434440)
101. M. Biselli, S. Gitto, A. Gramenzi, R. Di Donato, L. Brodosi, and M. Ravaioli Six score systems to evaluate candidates with advanced cirrhosis for orthotopic liver transplant: which is the winner? Liver Transpl 16 2010 964 973
102. J.D. Horton, F.L. San Miguel, and J.A. Ortiz Budd-Chiari syndrome: illustrated review of current management Liver Int 28 2008 455 466 (Pubitemid 351411131)
103. D.M. Heuman, A.A. Mihas, A. Habib, H.S. Gilles, R.T. Stravitz, and A.J. Sanyal MELD-XI: a rational approach to "Sickest First" liver transplantation in cirrhotic patients requiring anticoagulant therapy Liver Transpl 13 2007 30 37 (Pubitemid 46099971)