The semi-synthetic kaurane ent-16α-methoxykauran-19-oic acid induces vascular relaxation and hypotension in rats

European Journal of Pharmacology

Volumn 660, Issue 2-3, 2011, Pages 402-410

  Hipólito, Ulisses V ^a   Rocha, Juliana T ^a   Palazzin, Nathalia B ^a   Rodrigues, Gerson J ^a   Crestani, Carlos C ^b   Corrêa, Fernando M ^a   Bonaventura, Daniella ^c   Ambrosio, Sergio R ^d   Bendhack, Lusiane M ^a   Resstel, Leonardo B ^a   Tirapelli, Carlos R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^d UNIVERSIDADE DE FRANCA   (Brazil)

Author keywords

Ca2+; Diterpene; ent 16 methoxykauran 19 oic acid; Rat aorta; Relaxation

Indexed keywords

CALCIUM; CARDIOVASCULAR AGENT; DITERPENE; ENT 16ALPHA METHOXYKAURAN 19 OIC ACID; KAURENOIC ACID; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD VESSEL REACTIVITY; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; ENDOTHELIUM CELL; HYPOTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTION; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; AORTA; BLOOD PRESSURE; CALCIUM; CALCIUM CHLORIDE; DITERPENES, KAURANE; HYPOTENSION; INTRACELLULAR SPACE; MALE; PHENYLEPHRINE; POTASSIUM CHLORIDE; RATS; TIME FACTORS; VASODILATION;

EID: 79956118689     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.04.019     Document Type: Article

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