Characterisation of marrubenol, a diterpene extracted from Marrubium vulgare, as an L-type calcium channel blocker

British Journal of Pharmacology

Volumn 140, Issue 7, 2003, Pages 1211-1216

  El Bardai, Sanae ^a,b   Wibo, Maurice ^a   Hamaide, Marie Christine ^a   Lyoussi, Badiaa ^b   Quetin Leclercq, Joëlle ^a   Morel, Nicole ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b SIDI MOHAMED BEN ABDELLAH UNIVERSITY   (Morocco)

Author keywords

Ca 2+ channel blocker; Fura 2; L type Ca 2+ channel; Marrubenol

Indexed keywords

BARIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; DITERPENE; FURA 2; MANGANESE; MARRUBIUM VULGARE EXTRACT; NORADRENALIN; POTASSIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA; AORTA MEDIA; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; DATA ANALYSIS; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; ELECTRIC CURRENT; ELECTRIC POTENTIAL; FLUORESCENCE; IC 50; INHIBITION KINETICS; MARRUBIUM; MARRUBIUM VULGARE; MUSCLE RELAXATION; NONHUMAN; PATCH CLAMP; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER;

ANIMALS; AORTA; BARIUM; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT DYES; FURA-2; MALE; MARRUBIUM; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; PLANT EXTRACTS; POTASSIUM CHLORIDE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 1642422319     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705561     Document Type: Article

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