Intravenous administration of pravastatin immediately after middle cerebral artery occlusion reduces cerebral oedema in spontaneously hypertensive rats

European Journal of Pharmacology

Volumn 660, Issue 2-3, 2011, Pages 381-386

  Mariucci, Giuseppina ^a   Taha, Elena ^a   Tantucci, Michela ^a,b   Spaccatini, Cristiano ^a   Tozzi, Alessandro ^a,b   Ambrosini, Maria Vittoria ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

Cerebral oedema; eNOS; Focal cerebral ischemia; Neuroprotection; Pravastatin

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLIAL FIBRILLARY ACIDIC PROTEIN; PRAVASTATIN; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG EFFECT; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTICHOLESTEREMIC AGENTS; APOPTOSIS; ASTROCYTES; BRAIN EDEMA; ENZYME INDUCTION; INFARCTION, MIDDLE CEREBRAL ARTERY; INJECTIONS, INTRAVENOUS; MALE; NITRIC OXIDE SYNTHASE TYPE III; PRAVASTATIN; RATS; RATS, INBRED SHR;

EID: 79956092229     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.04.002     Document Type: Article

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