Application of the dried spot sampling technique for rat cerebrospinal fluid sample collection and analysis

Journal of Pharmaceutical and Biomedical Analysis

Volumn 55, Issue 5, 2011, Pages 1201-1207

  Rago, Brian ^a   Liu, JianHua ^a   Tan, Beijing ^a   Holliman, Christopher ^a  

^a PFIZER INC   (United States)

Author keywords

Bioanalytical; Cerebrospinal fluid (CSF); Dried blood spot (DBS); LC MS MS; PHA 00543613

Indexed keywords

CHOLINERGIC RECEPTOR STIMULATING AGENT; PHA 00543613; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD; CEREBROSPINAL FLUID; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIQUID; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SAMPLING;

ANALYTIC SAMPLE PREPARATION METHODS; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOOD CHEMICAL ANALYSIS; CALIBRATION; CEREBROSPINAL FLUID; CHEMISTRY TECHNIQUES, ANALYTICAL; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; MALE; MODELS, CHEMICAL; QUINUCLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; REPRODUCIBILITY OF RESULTS;

EID: 79956066684     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.03.025     Document Type: Article

References (16)

1. Guthrie R., Susi A. A Simple phenylalanine method for detecting phenylkeonuria in large populations of newborn infants. Pediatrics 1963, 32:338-343.
2. United States General Accounting Office Report to Congressional Requesters: Newborn Screening Characteristics of State Programs GAO-03-449 Washington D.C. 2003.
3. Li W., Tse F. Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small molecules. Biomed. Chromatogr. 2010, 24:49-65.
4. Spooner N., Lad R., Barfield M. Dried Blood spots as a sample collection technique for the determination of pharmacokinetcs in clinical studies: considerations for the validation of a quantitative bioanalytical method. Anal. Chem. 2009, 81:1557-1563.
5. Barfield M., Spooner N., Lad R., Parry S., Fowles S. Application of dried blood spots combined with HPLC-MS/MS for the quantification of acetaminophen in toxicokinetic studies. J. Chromatogr. B 2008, 870:32-37.
6. ter Heine R., Rosing H., Rosing H., van Gorp E.C.M., Mulder J.W., Beijnen J.H., Huitema A.D.R. Quantification of etravirine (TMC125) in plasma, dried blood spots and peripheral blood mononuclear cell lysate by liquid chromatography tandem mass spectrometry. J. Pharm. Biomed. Anal. 2009, 49:393-400.
7. Heinig K., Bucheli F., Hartenbach R., Gajate-Perez A. Determination of mycophenolic acid and its phenyl glucoronide in human plasma, ultrafiltrate, blood, DBS and dried plasma spots. Bioanalysis 2010, 2:1423-1435.
8. Van Kuilenburg A, Van Lenthe H., Loffler M., Van Gennip A. Analysis of Pyrimidine Synthesis " de Novo" intermediates in urine and dried urine filter-paper strips with HPLC-electrospray tandem mass spectrometery. Clin. Chem. 2004, 50:2117-2124.
9. Christianson C., Laine D., Zimmer J., Johnson C., Sheaff C., Carpenter A., Needham S. Development and validation of an HPLC/MS/MS method for the analysis of dexamethasone from pig synovial fluid using dried blood spotting. Bioanalysis 2010, 2:1829-1837.
10. Shen D., Artru A., Adkison K. Prinicples and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics. Adv. Drug Deliv. Rev. 2004, 56:1825-1857.
11. King R., Bonfiglio R., Fernandez-Metzler C., Miller-Stein C., Olah T. Mechanistic investigation of ionization suppression in electrospray ionization. J. Am. Soc. Mass Spectrom. 2000, 11:942-950.
12. Xu Y., Du L., Rose M., Fu I., Woolf E., Musson D. Concerns in the development of an assay for determination of a highly conjugated adsorption-prone compound in human urine. J. Chromatogr. B. 2005, 818:241-248.
13. Kadar E., Su Y., Zhang Y., Tweed J., Wujcik C. Evaluation of the relationship between a pharmaceutical compound's distribution coefficient, logD and adsorption loss to polypropylene in urine and CSF. Bioanalysis 2010, 2:755-767.
14. Guidance for Industry Bioanalytical Method Validation May 2001, US Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Veterinary Medicine (CVM).
15. Wishka D.G, Walker D.P., Yates K.M., Reitz S.C., Jia S., Olson J.K., Jacobsen E.J., Wolfe M.L., Groppi V.E., Hanchar A.J., Thornburgh B.A., Cortes-Burgos L.A., Wong E.H., Staton B.A., Raub T.J., Higdon N.R., Wall T.M., Hurst R.S., Walters R.R., Hoffman W.E., Hajos M., Franklin S., Carey G., Gold L.H., Cook K.K., Sands S.B., Zhao S.X., Soglia J.R., Kalgutkar A.S., Americ S.P., Rogers B.N. Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure-activity relationship. J. Med. Chem. 2006, 49:4425-4436.
16. Osgood S., Becker S., Gorczyca R., Buchholz L., Rollema H., Shaffer C. Low Level LC-MS/MS quantitation of psychotherapeutics in extracellular fluid for rat microdialysis studies. Poster presented at the 57th ASMS Conference on Mass Spectrometry and Allied Topics 2009.