메뉴 건너뛰기




Volumn 50, Issue 11, 2004, Pages 2117-2124

Analysis of pyrimidine synthesis "de novo" intermediates in urine and dried urine filter-paper strips with HPLC-electrospray tandem mass spectrometry

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID DERIVATIVE; DIHYDROOROTIC ACID DERIVATIVE; NITROGEN 15; OROTIC ACID DERIVATIVE; OROTIDINE; PYRIMIDINE; URACIL DERIVATIVE; URIDINE DERIVATIVE;

EID: 7044247759     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2004.038869     Document Type: Article
Times cited : (33)

References (24)
  • 1
    • 0037300817 scopus 로고    scopus 로고
    • De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways
    • Huang M, Graves LM. De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways. Cell Mol Life Sci 2003;60:321-36.
    • (2003) Cell Mol Life Sci , vol.60 , pp. 321-336
    • Huang, M.1    Graves, L.M.2
  • 2
    • 0036851697 scopus 로고    scopus 로고
    • Inhibitors of de novo nucleotide biosynthesis as drugs
    • Christopherson RI, Lyons SD, Wilson PK. Inhibitors of de novo nucleotide biosynthesis as drugs. Acc Chem Res 2002;35:961-71.
    • (2002) Acc Chem Res , vol.35 , pp. 961-971
    • Christopherson, R.I.1    Lyons, S.D.2    Wilson, P.K.3
  • 3
  • 4
    • 0032374063 scopus 로고    scopus 로고
    • Purification of human dihydro-orotate dehydro-genase and its inhibition by A77 1726, the active metabolite of leflunomide
    • Bruneau JM, Yea CM, Spinella-Jaegle S, Fudali C, Woodward K, Robson PA, et al. Purification of human dihydro-orotate dehydro-genase and its inhibition by A77 1726, the active metabolite of leflunomide. Biochem J 1998;336(Pt 2):299-303.
    • (1998) Biochem J , vol.336 , Issue.PART 2 , pp. 299-303
    • Bruneau, J.M.1    Yea, C.M.2    Spinella-Jaegle, S.3    Fudali, C.4    Woodward, K.5    Robson, P.A.6
  • 5
    • 0002040183 scopus 로고    scopus 로고
    • Hereditary orotic aciduria and other disorders of pyrimidine metabolism
    • Scriver CR, Beaudet AL, Sly WS, Valle D, eds. New York: McGraw-Hill Medical Publishing Division
    • Webster DR, Becroft DMO, van Gennip AH, van Kuilenburg ABP. Hereditary orotic aciduria and other disorders of pyrimidine metabolism. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The metabolic and molecular bases of inherited disease. New York: McGraw-Hill Medical Publishing Division, 2001:2663-702.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 2663-2702
    • Webster, D.R.1    Becroft, D.M.O.2    Van Gennip, A.H.3    Van Kuilenburg, A.B.P.4
  • 6
    • 0037027859 scopus 로고    scopus 로고
    • Diagnostic value of urinary orotic acid levels: Applicable separation methods
    • Salerno C, Crifo C. Diagnostic value of urinary orotic acid levels: applicable separation methods. J Chromatogr B Analyt Technol Biomed Life Sci 2002;781:57-71.
    • (2002) J Chromatogr B Analyt Technol Biomed Life Sci , vol.781 , pp. 57-71
    • Salerno, C.1    Crifo, C.2
  • 8
    • 0014622121 scopus 로고
    • Modified methods for the determination of carbamyl aspartate
    • Prescott LM, Jones ME. Modified methods for the determination of carbamyl aspartate. Anal Biochem 1969;32:408-19.
    • (1969) Anal Biochem , vol.32 , pp. 408-419
    • Prescott, L.M.1    Jones, M.E.2
  • 9
    • 0017258262 scopus 로고
    • Increased excretion of N-carbamoyl compounds in patients with urea cycle defects
    • Oberholzer VG, Palmer T. Increased excretion of N-carbamoyl compounds in patients with urea cycle defects. Clin Chim Acta 1976;68:73-8.
    • (1976) Clin Chim Acta , vol.68 , pp. 73-78
    • Oberholzer, V.G.1    Palmer, T.2
  • 10
    • 0015510914 scopus 로고
    • Enzymatic spectrophotometric assay for dihydroorotic acid in serum and urine
    • Rogers LE, Nicolaisen K. Enzymatic spectrophotometric assay for dihydroorotic acid in serum and urine. Experientia 1972;28:1258-9.
    • (1972) Experientia , vol.28 , pp. 1258-1259
    • Rogers, L.E.1    Nicolaisen, K.2
  • 11
    • 0016584397 scopus 로고
    • Determination of orotic and dihydroorotic acids in biological fluids and tissues
    • Kesner L, Aronson FL, Silverman M, Chan PC. Determination of orotic and dihydroorotic acids in biological fluids and tissues. Clin Chem 1975;21:353-5.
    • (1975) Clin Chem , vol.21 , pp. 353-355
    • Kesner, L.1    Aronson, F.L.2    Silverman, M.3    Chan, P.C.4
  • 13
    • 0036230654 scopus 로고    scopus 로고
    • Separation of N-carbamoyl aspartate and L-dihydroorotate from serum by high-performance liquid chromatography with fluorimetric detection
    • Hayek-Ouassini M, Henseling J, Löffler M. Separation of N-carbamoyl aspartate and L-dihydroorotate from serum by high-performance liquid chromatography with fluorimetric detection. Chromatographia 2002;55:411-5.
    • (2002) Chromatographia , vol.55 , pp. 411-415
    • Hayek-Ouassini, M.1    Henseling, J.2    Löffler, M.3
  • 14
    • 0032953027 scopus 로고    scopus 로고
    • The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease
    • Bonham JR, Guthrie P, Downing M, Allen JC, Tanner MS, Sharrard M, et al. The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease. J Inherit Metab Dis 1999;22:174-84.
    • (1999) J Inherit Metab Dis , vol.22 , pp. 174-184
    • Bonham, J.R.1    Guthrie, P.2    Downing, M.3    Allen, J.C.4    Tanner, M.S.5    Sharrard, M.6
  • 15
    • 0028937251 scopus 로고
    • Quantification of orotic acid in dried filter-paper urine samples by stable isotope dilution
    • McCann MT, Thompson MM, Gueron IC, Tuchman M. Quantification of orotic acid in dried filter-paper urine samples by stable isotope dilution. Clin Chem 1995;41:739-43.
    • (1995) Clin Chem , vol.41 , pp. 739-743
    • McCann, M.T.1    Thompson, M.M.2    Gueron, I.C.3    Tuchman, M.4
  • 16
    • 0037369826 scopus 로고    scopus 로고
    • Rapid determination of orotic acid in urine by liquid chromatography-electrospray tandem mass spectrometry
    • Rashed MS, Jacob M, Al Amoudi M, Rahbeeni Z, Al Sayed MAD, Al Ahaidib L, et al. Rapid determination of orotic acid in urine by liquid chromatography-electrospray tandem mass spectrometry. Clin Chem 2003;49:499-501.
    • (2003) Clin Chem , vol.49 , pp. 499-501
    • Rashed, M.S.1    Jacob, M.2    Al Amoudi, M.3    Rahbeeni, Z.4    Al Sayed, M.A.D.5    Al Ahaidib, L.6
  • 17
    • 0034075405 scopus 로고    scopus 로고
    • Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips
    • Ito T, van Kuilenburg ABP, Bootsma AH, Haasnoot AJ, van Cruchten AG, Wada Y, et al. Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips. Clin Chem 2000;46:445-52.
    • (2000) Clin Chem , vol.46 , pp. 445-452
    • Ito, T.1    Van Kuilenburg, A.B.P.2    Bootsma, A.H.3    Haasnoot, A.J.4    Van Cruchten, A.G.5    Wada, Y.6
  • 19
    • 0036123005 scopus 로고    scopus 로고
    • Capillary electrophoresis for detection of inherited disorders of purine and pyrimidine metabolism: A selective approach
    • Friedecky D, Adam T, Bartak P. Capillary electrophoresis for detection of inherited disorders of purine and pyrimidine metabolism: a selective approach. Electrophoresis 2002;23:565-71.
    • (2002) Electrophoresis , vol.23 , pp. 565-571
    • Friedecky, D.1    Adam, T.2    Bartak, P.3
  • 20
    • 0029800334 scopus 로고    scopus 로고
    • The B form of dihydroorotate dehydrogenase from Lactococcus lactis consists of two different subunits, encoded by the pyrDb and pyrK genes, and contains FMN, FAD, and [FeS] redox centers
    • Nielsen FS, Andersen PS, Jensen KF. The B form of dihydroorotate dehydrogenase from Lactococcus lactis consists of two different subunits, encoded by the pyrDb and pyrK genes, and contains FMN, FAD, and [FeS] redox centers. J Biol Chem 1996;271:29359-65.
    • (1996) J Biol Chem , vol.271 , pp. 29359-29365
    • Nielsen, F.S.1    Andersen, P.S.2    Jensen, K.F.3
  • 22
    • 0036083066 scopus 로고    scopus 로고
    • Leflunomide for the treatment of rheumatoid arthritis and autoimmunity
    • Sanders S, Harisdangkul V. Leflunomide for the treatment of rheumatoid arthritis and autoimmunity. Am J Med Sci 2002;323:190-3.
    • (2002) Am J Med Sci , vol.323 , pp. 190-193
    • Sanders, S.1    Harisdangkul, V.2
  • 23
    • 0025260156 scopus 로고
    • Purines and pyrimidines in malarial parasites
    • Gero AM, O'Sullivan WJ. Purines and pyrimidines in malarial parasites. Blood Cells 1990;16:467-84.
    • (1990) Blood Cells , vol.16 , pp. 467-484
    • Gero, A.M.1    O'Sullivan, W.J.2
  • 24
    • 0037093447 scopus 로고    scopus 로고
    • Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure
    • van Kuilenburg ABP, Dobritzsch D, Meinsma JR, Haasjes J, Waterham HR, Nowaczyk MJM, et al. Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure. Biochem J 2002;364:157-63.
    • (2002) Biochem J , vol.364 , pp. 157-163
    • Van Kuilenburg, A.B.P.1    Dobritzsch, D.2    Meinsma, J.R.3    Haasjes, J.4    Waterham, H.R.5    Nowaczyk, M.J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.