Quantification of etravirine (TMC125) in plasma, dried blood spots and peripheral blood mononuclear cell lysate by liquid chromatography tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 49, Issue 2, 2009, Pages 393-400

  ter Heine, R ^a   Rosing, H ^a   van Gorp, E C M ^a   Mulder, J W ^a   Beijnen, J H ^a   Huitema, A D R ^a  

^a SLOTERVAART HOSPITAL   (Netherlands)

Author keywords

Etravirine; LC MS MS; Pharmacology; TDM; TMC125

Indexed keywords

ACETIC ACID; ACETONITRILE; BUFFER; ETRAVIRINE; METHANOL; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZINC SULFATE;

ARTICLE; BLOOD ANALYSIS; CELL LYSATE; DIAGNOSTIC ACCURACY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG MONITORING; DRUG STABILITY; FLOW RATE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LIQUID CHROMATOGRAPHY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRECIPITATION; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; REACTION OPTIMIZATION; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

ACETONITRILES; ATMOSPHERIC PRESSURE; BIOLOGICAL ASSAY; CALIBRATION; CELL EXTRACTS; CHROMATOGRAPHY, LIQUID; DESICCATION; DRUG MONITORING; DRUG STABILITY; DRUG STORAGE; FREEZING; HIV PROTEASE INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; LEUKOCYTES, MONONUCLEAR; METHANOL; MOLECULAR STRUCTURE; PARTICLE SIZE; PYRIDAZINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TEMPERATURE; WATER; ZINC SULFATE;

EID: 59049090021     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.10.040     Document Type: Article

References (10)

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