The conflicting effects of maternal nutrient restriction and early-life obesity on renal health

Proceedings of the Nutrition Society

Volumn 70, Issue 2, 2011, Pages 268-275

  Fainberg, H P ^a   Budge, H ^b   Symonds, M E ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Fetal programming; Maternal nutrient restriction; Renal health

Indexed keywords

BLOOD PRESSURE; CONFERENCE PAPER; DISEASE ASSOCIATION; FETAL MALNUTRITION; GLOMERULOSCLEROSIS; GLOMERULUS FILTRATION RATE; HUMAN; INFLAMMATION; KIDNEY DISEASE; KIDNEY STRUCTURE; MATERNAL NUTRITION; METABOLIC SYNDROME X; METABOLISM; NONHUMAN; NUTRIENT LIMITATION; OBESITY;

ADIPOSE TISSUE; ANIMALS; FEMALE; FETAL DEVELOPMENT; HUMANS; INFLAMMATION; KIDNEY; KIDNEY DISEASES; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; METABOLIC SYNDROME X; MYOCARDIUM; OBESITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

ANIMALIA; OVIS;

EID: 79956035972     PISSN: 00296651     EISSN: 14752719     Source Type: Journal    
DOI: 10.1017/S0029665110004921     Document Type: Conference Paper

References (75)

1. Hsu CY, McCulloch CE, Iribarren C et al. (2006) Body mass index and risk for end-stage renal disease. Ann Intern Med 144, 21-28. (Pubitemid 46780716)
2. Eriksson JG, Forsen T, Tuomilehto J et al. (2001) Early growth and coronary heart disease in later life: longitudinal study. Br Med J 322, 949-953. (Pubitemid 32374683)
3. Wang L, Kong L, Wu F, et al. (2005) Preventing chronic diseases in China. Lancet 366, 1821-1824. (Pubitemid 41642648)
4. Hales CN & Barker DJ (2001) The thrifty phenotype hypothesis. Br Med Bull 60, 5-20. (Pubitemid 34123501)
5. Barker DJ, Osmond C, Golding J et al. (1989) Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. Br Med J 298, 564-567. (Pubitemid 19072097)
6. Wadsworth ME, Cripps HA, Midwinter RE et al. (1985) Blood pressure in a national birth cohort at the age of 36 related to social and familial factors, smoking, and body mass. Br Med J (Clin Res Ed ) 291, 1534-1538. (Pubitemid 16183916)
7. Zidar N, Avgustin Cavic M, Kenda RB et al. (1998) Unfavorable course of minimal change nephrotic syndrome in children with intrauterine growth retardation. Kidney Int 54, 1320-1323. (Pubitemid 28449921)
8. Ozanne SE & Hales CN (2004) Lifespan: catch-up growth and obesity in male mice. Nature 427, 411-412. (Pubitemid 38168484)
9. Kermack WO, McKendrick AG & McKinlay PL (2001) Death-rates in Great Britain and Sweden. Some general regularities and their significance. Int J Epidemiol 30, 678-683. (Pubitemid 32827363)
10. Hales CN, Barker DJ, Clark PM et al. (1991) Fetal and infant growth and impaired glucose tolerance at age 64. Br Med J 303, 1019-1022.
11. Nelson RG, Morgenstern H & Bennett PH (1998) Birth weight and renal disease in Pima Indians with type 2 diabetes mellitus. Am J Epidemiol 148, 650-656. (Pubitemid 28498432)
12. Hughson M, Farris 3rd AB, Douglas-Denton R et al. (2003) Glomerular number and size in autopsy kidneys: the relationship to birth weight. Kidney Int 63, 2113-2122. (Pubitemid 36605822)
13. Painter RC, Roseboom TJ & Bleker OP (2005) Prenatal exposure to the Dutch famine and disease in later life: an overview. Reprod Toxicol 20, 345-352. (Pubitemid 40949554)
14. Ravelli AC, van der Meulen JH, Michels RP et al. (1998) Glucose tolerance in adults after prenatal exposure to famine. Lancet 351, 173-177. (Pubitemid 28037007)
15. Roseboom TJ, van der Meulen JH, Osmond C et al. (2000) Coronary heart disease after prenatal exposure to the Dutch famine, 1944-1945. Heart 84, 595-598.
16. Hoek HW, Brown AS & Susser E (1998) The Dutch famine and schizophrenia spectrum disorders. Soc Psychiatry Psychiatr Epidemiol 33, 373-379. (Pubitemid 28377065)
17. Brennan KA, Gopalakrishnan GS, Kurlak L et al. (2005) Impact of maternal undernutrition and fetal number on glucocorticoid, growth hormone and insulin-like growth factor receptor mRNA abundance in the ovine fetal kidney. Reproduction 129, 151-159. (Pubitemid 40331007)
18. Moritz KM, Boon WM & Wintour EM (2005) Glucocorticoid programming of adult disease. Cell Tissue Res 322, 81-88. (Pubitemid 41677658)
19. Bard JB (2002) Growth and death in the developing mammalian kidney: signals, receptors and conversations. Bioessays 24, 72-82. (Pubitemid 34108422)
20. Brenner B & Rector F (2007) The Kidney. Philadelphia, PA: W.B. Saunders Company.
21. Godfrey K, Robinson S, Barker DJ et al. (1996) Maternal nutrition in early and late pregnancy in relation to placental and fetal growth. Br Med J 312, 410-414. (Pubitemid 26055356)
22. Ong KK & Dunger DB (2004) Birth weight, infant growth and insulin resistance. Eur J Endocrinol 151, Suppl. 3, U131-U139. (Pubitemid 39627067)
23. Ymer SI & Herington AC (1992) Developmental expression of the growth hormone receptor gene in rabbit tissues. Mol Cell Endocrinol 83, 39-49.
24. Holzenberger M, Hamard G, Zaoui R et al. (2001) Experimental IGF-I receptor deficiency generates a sexually dimorphic pattern of organ-specific growth deficits in mice, affecting fat tissue in particular. Endocrinology 142, 4469-4478. (Pubitemid 32907078)
25. Hirschberg R & Kopple JD (1989) Effects of growth hormone and IGF-I on renal function. Kidney Int Suppl 27, S20-S26. (Pubitemid 19285070)
26. Liu ZZ, Wada J, Alvares K et al. (1993) Distribution and relevance of insulin-like growth factor-I receptor in metanephric development. Kidney Int 44, 1242-1250. (Pubitemid 23353305)
27. Bridgewater DJ, Dionne JM, Butt MJ et al. (2008) The role of the type I insulin-like growth factor receptor (IGF-IR) in glomerular integrity. Growth Horm IGF Res 18, 26-37. (Pubitemid 351228805)
28. Schubring C, Siebler T, Kratzsch J et al. (1999) Leptin serum concentrations in healthy neonates within the first week of life: relation to insulin and growth hormone levels, skinfold thickness, body mass index and weight. Clin Endocrinol (Oxf) 51, 199-204. (Pubitemid 29378905)
29. Schubring C, Kiess W, Englaro P et al. (1997) Levels of leptin in maternal serum, amniotic fluid, and arterial and venous cord blood: relation to neonatal and placental weight. J Clin Endocrinol Metab 82, 1480-1483. (Pubitemid 27200422)
30. Schwartz MW, Baskin DG, Bukowski TR et al. (1996) Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45, 531-535. (Pubitemid 26111317)
31. Bell AW & Ehrhardt RA (2002) Regulation of placental nutrient transport and implications for fetal growth. Nutr Res Rev 15, 211-230. (Pubitemid 35423604)
32. Senaris R, Garcia-Caballero T, Casabiell X et al. (1997) Synthesis of leptin in human placenta. Endocrinology 138, 4501-4504. (Pubitemid 27408503)
33. Bispham J, Gopalakrishnan GS, Dandrea J et al. (2003) Maternal endocrine adaptation throughout pregnancy to nutritional manipulation: consequences for maternal plasma leptin and cortisol and the programming of fetal adipose tissue development. Endocrinology 144, 3575-3585. (Pubitemid 36904437)
34. Serradeil-Le Gal C, Raufaste D, Brossard G et al. (1997) Characterization and localization of leptin receptors in the rat kidney. FEBS Lett 404, 185-191. (Pubitemid 27113450)
35. Beltowski J, Jamroz-Wisniewska A, Borkowska E et al. (2004) Up-regulation of renal Na +, K+ -ATPase: the possible novel mechanism of leptin-induced hypertension. Pol J Pharmacol 56, 213-222. (Pubitemid 38931388)
36. Hall JE (2003) The kidney, hypertension, and obesity. Hypertension 41, 625-633. (Pubitemid 36314565)
37. Rahmouni K, Morgan DA, Morgan GM et al. (2005) Role of selective leptin resistance in diet-induced obesity hypertension. Diabetes 54, 2012-2018. (Pubitemid 40911263)
38. Symonds ME, Stephenson T, Gardner DS et al. (2007) Longterm effects of nutritional programming of the embryo and fetus: mechanisms and critical windows. Reprod Fertil Dev 19, 53-63. (Pubitemid 46044731)
39. Whorwood CB, Firth KM, Budge H et al. (2001) Maternal undernutrition during early to midgestation programs tissuespecific alterations in the expression of the glucocorticoid receptor, 11beta-hydroxysteroid dehydrogenase isoforms, and type 1 angiotensin ii receptor in neonatal sheep. Endocrinology 142, 2854-2864. (Pubitemid 32575520)
40. Williams PJ, Kurlak LO, Perkins AC et al. (2007) Hypertension and impaired renal function accompany juvenile obesity: the effect of prenatal diet. Kidney Int 72, 279-289. (Pubitemid 47172368)
41. Bispham J, Gardner DS, Gnanalingham MG et al. (2005) Maternal nutritional programming of fetal adipose tissue development: differential effects on messenger ribonucleic acid abundance for uncoupling proteins and peroxisome proliferator-activated and prolactin receptors. Endocrinology 146, 3943-3949. (Pubitemid 41175765)
42. Gopalakrishnan GS, Gardner DS, Rhind SM et al. (2004) Programming of adult cardiovascular function after early maternal undernutrition in sheep. Am J Physiol Regul Integr Comp Physiol 287, R12-R20. (Pubitemid 38856305)
43. Symonds ME, Sebert SP, Hyatt MA et al. (2009) Nutritional programming of the metabolic syndrome. Nat Rev Endocrinol 5, 604-610.
44. Gopalakrishnan GS, Gardner DS, Dandrea J et al. (2005) Influence of maternal pre-pregnancy body composition and diet during early-mid pregnancy on cardiovascular function and nephron number in juvenile sheep. Br J Nutr 94, 938-947. (Pubitemid 43092426)
45. Stein CE, Fall CH, Kumaran K et al. (1996) Fetal growth and coronary heart disease in south India. Lancet 348, 1269-1273. (Pubitemid 26377238)
46. Ogilvy-Stuart AL, Hands SJ, Adcock CJ et al. (1998) Insulin, insulin-like growth factor I (IGF-I), IGF-binding protein-1, growth hormone, and feeding in the newborn. J Clin Endocrinol Metab 83, 3550-3557. (Pubitemid 28500888)
47. Low LC, Tam SY, Kwan EY et al. (2001) Onset of significant GH dependence of serum IGF-I and IGF-binding protein 3 concentrations in early life. Pediatr Res 50, 737-742. (Pubitemid 33121644)
48. Tannenbaum GS, Guyda HJ & Posner BI (1983) Insulinlike growth factors: a role in growth hormone negative feedback and body weight regulation via brain. Science 220, 77-79. (Pubitemid 13161713)
49. Adelman RD, Restaino IG, Alon US et al. (2001) Proteinuria and focal segmental glomerulosclerosis in severely obese adolescents. J Pediatr 138, 481-485. (Pubitemid 32319719)
50. Chagnac A, Weinstein T, Korzets A et al. (2000) Glomerular hemodynamics in severe obesity. Am J Physiol Renal Physiol 278, F817-F822. (Pubitemid 30351084)
51. Praga M, Hernandez E, Herrero JC et al. (2000) Influence of obesity on the appearance of proteinuria and renal insufficiency after unilateral nephrectomy. Kidney Int 58, 2111-2118.
52. Rea DJ, Heimbach JK, Grande JP et al. (2006) Glomerular volume and renal histology in obese and non-obese living kidney donors. Kidney Int 70, 1636-1641. (Pubitemid 44607000)
53. Nakamura M, Onoda T, Itai K et al. (2004) Association between serum C-reactive protein levels and microalbuminuria: a population-based cross-sectional study in northern Iwate, Japan. Intern Med 43, 919-925. (Pubitemid 39534794)
54. Ramkumar N, Cheung AK, Pappas LM et al. (2004) Association of obesity with inflammation in chronic kidney disease: a cross-sectional study. J Ren Nutr 14, 201-207. (Pubitemid 39360975)
55. Hotamisligil GS, Shargill NS & Spiegelman BM (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259, 87-91. (Pubitemid 23036092)
56. Cinti S, Mitchell G, Barbatelli G et al. (2005) Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 46, 2347-2355. (Pubitemid 41532523)
57. Fried SK, Bunkin DA & Greenberg AS (1998) Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 83, 847-850. (Pubitemid 28496456)
58. Massiera F, Bloch-Faure M, Ceiler D et al. (2001) Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation. FASEB J 15, 2727-2729.
59. van Harmelen V, Skurk T, Rohrig K et al. (2003) Effect of BMI and age on adipose tissue cellularity and differentiation capacity in women. Int J Obes Relat Metab Disord 27, 889-895. (Pubitemid 36918609)
60. Aubert J, Darimont C, Safonova I et al. (1997) Regulation by glucocorticoids of angiotensinogen gene expression and secretion in adipose cells. Biochem J 328 (Pt 2), 701-706. (Pubitemid 27515619)
61. Hasdan G, Benchetrit S, Rashid G et al. (2002) Endothelial dysfunction and hypertension in 5/6 nephrectomized rats are mediated by vascular superoxide. Kidney Int 61, 586-590. (Pubitemid 34102600)
62. Johnson RJ, Alpers CE, Yoshimura A et al. (1992) Renal injury from angiotensin II-mediated hypertension. Hypertension 19, 464-474.
63. Abrass CK, Raugi GJ, Gabourel LS et al. (1988) Insulin and insulin-like growth factor I binding to cultured rat glomerular mesangial cells. Endocrinology 123, 2432-2439.
64. Berfield AK, Andress DL & Abrass CK (2002) IGF-1- induced lipid accumulation impairs mesangial cell migration and contractile function. Kidney Int 62, 1229-1237.
65. Saito K, Ishizaka N, Hara M et al. (2005) Lipid accumulation and transforming growth factor-beta upregulation in the kidneys of rats administered angiotensin II. Hypertension 46, 1180-1185. (Pubitemid 41533023)
66. Lauzier MC, Page EL, Michaud MD et al. (2007) Differential regulation of hypoxia-inducible factor-1 through receptor tyrosine kinase transactivation in vascular smooth muscle cells. Endocrinology 148, 4023-4031. (Pubitemid 47105854)
67. Lubbers DW & Baumgartl H (1997) Heterogeneities and profiles of oxygen pressure in brain and kidney as examples of the pO2 distribution in the living tissue. Kidney Int 51, 372-380. (Pubitemid 27088146)
68. Wiggins JE, Goyal M, Sanden SK et al. (2005) Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction. J Am Soc Nephrol 16, 2953-2966. (Pubitemid 44743493)
69. Praga M, Hernandez E, Morales E et al. (2001) Clinical features and long-term outcome of obesity-associated focal segmental glomerulosclerosis. Nephrol Dial Transplant 16, 1790-1798. (Pubitemid 32821410)
70. Advani A, Kelly DJ, Advani SL et al. (2007) Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions. Proc Natl Acad Sci USA 104, 14448-14453. (Pubitemid 350003281)
71. Sebert SP, Hyatt MA, Chan LL et al. (2009) Maternal nutrient restriction between early and midgestation and its impact upon appetite regulation after juvenile obesity. Endocrinology 150, 634-641.
72. Sharkey D, Gardner DS, Fainberg HP et al. (2009) Maternal nutrient restriction during pregnancy differentially alters the unfolded protein response in adipose and renal tissue of obese juvenile offspring. FASEB J 5, 1314-1324.
73. Chan LL, Sebert SP, Hyatt MA et al. (2009) Effect of maternal nutrient restriction from early to midgestation on cardiac function and metabolism after adolescent-onset obesity. Am J Physiol Regul Integr Comp Physiol 296, R1455-R1463.
74. Zhou YT, Grayburn P, Karim A et al. (2000) Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci USA 97, 1784-1789. (Pubitemid 30118520)
75. Henegar JR, Bigler SA, Henegar LK et al. (2001) Functional and structural changes in the kidney in the early stages of obesity. J Am Soc Nephrol 12, 1211-1217. (Pubitemid 32472634)