Chloroquine causes lysosomal dysfunction in neural retina and RPE: Implications for retinopathy

Current Eye Research

Volumn 28, Issue 4, 2004, Pages 277-284

  Mahon, G J ^a   Anderson, H R ^b   Gardiner, T A ^b   McFarlane, S ^b   Archer, D B ^a,b   Stitt, A W ^b  

^a ROYAL VICTORIA HOSPITAL   (United Kingdom)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Chloroquine; Lysosomes; Retinopathy; RPE

Indexed keywords

CHLOROQUINE; FLUORESCEIN ISOTHIOCYANATE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; LYSOSOME; MALE; NERVE CELL; NONHUMAN; OSMOSIS; PATHOGENICITY; PATHOPHYSIOLOGY; PH; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RAT; RAT STRAIN; RETINA CELL; RETINA NERVE CELL; RETINOPATHY; STEREOLOGY;

ANIMALS; ANTIRHEUMATIC AGENTS; CELL CULTURE TECHNIQUES; CHLOROQUINE; CYTOPLASMIC GRANULES; DRUG IMPLANTS; HYDROGEN-ION CONCENTRATION; INFUSION PUMPS, IMPLANTABLE; LIPOFUSCIN; LYSOSOMES; MALE; PHAGOCYTOSIS; PHAGOSOMES; PIGMENT EPITHELIUM OF EYE; RATS; RETINA; RETINAL DISEASES; ROD OUTER SEGMENTS;

EID: 1842866266     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.28.4.277.27835     Document Type: Article

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