Protective effects of Chlorella-derived peptide on UVB-induced production of MMP-1 and degradation of procollagen genes in human skin fibroblasts

Regulatory Toxicology and Pharmacology

Volumn 60, Issue 1, 2011, Pages 112-119

  Chen, Chiu Lan ^a   Liou, Shu Fen ^a   Chen, Su Jong ^a   Shih, Mei Fen ^a  

^a CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

C fos; C jun; Chlorella; CYR61; MCP 1; MMP 1; Procollagen; Skin fibroblasts; TbRII; UVB

Indexed keywords

CHLORELLA DERIVED PEPTIDE; CYSTEINE RICH PROTEIN 61; INTERSTITIAL COLLAGENASE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROCOLLAGEN; PROTEIN C FOS; PROTEIN C JUN; RADIOPROTECTIVE AGENT; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CELL PROTECTION; CELL VIABILITY; CHLORELLA; COLLAGEN DEGRADATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION EXPOSURE; RADIATION PROTECTION; SKIN FIBROBLAST; ULTRAVIOLET B RADIATION;

CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINE CCL2; CHLORELLA; CYSTEINE-RICH PROTEIN 61; FIBROBLASTS; GENE EXPRESSION; HUMANS; MATRIX METALLOPROTEINASE 1; PEPTIDES; PLANT EXTRACTS; PLANT PROTEINS; PROCOLLAGEN; SKIN; TRANSCRIPTION FACTOR AP-1; ULTRAVIOLET RAYS;

EID: 79956005650     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2011.03.001     Document Type: Article

References (52)

1. Brennan M., Bhatti H., Nerusu K.C., Bhagavathula N., Kang S., Fisher G.J., Varan J., Voorhees J.J. Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin. Photochem. Photobiol. 2003, 78:43-48.
2. Chen C.-C., Mo F.-E., Lau L. The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. J. Biol. Chem. 2001, 276:47329-47337.
3. Cheng F.C., Lin A., Feng J.J., Mizoguchi T., Takekoshi H., Kubota H., Kato Y., Naok Y. Effects of Chlorella on activities of protein tyrosine phosphatases, matrix metalloproteinases, caspases, cytokine release, B and T cell proliferations, and phorbol ester receptor binding. J. Med. Food. 2004, 7:146-152.
4. Cherng J.Y., Shih M.F. Preventing dyslipidemia by Chlorella pyrenoidosa in rats and hamsters after chronic high fat diet treatment. Life Sci. 2005, 76:3001-3013.
5. Cherng J.Y., Shih M.F. Potential hypoglycemic effects of Chlorella in streptozotocin-induced diabetic Mice. Life Sci. 2005, 77:980-990.
6. Cherng J.Y., Shih M.F. Improving glycogenesis in streptozocin (STZ) diabetic mice after administration of green algae Chlorella. Life Sci. 2006, 78:1181-1186.
7. Cherng J.Y., Liu C., Shen C.R., Lin H.H., Shih M.F. Beneficial effects of Chlorella-11 peptide on blocking the LPS-induced macrophage activation and alleviating the thermal injury induced inflammation in rats. Int. J. Immunopathol. Pharmacol. 2010, 23:811-820.
8. Debacq-Chainiaux F., Borlon C., Pascal T., Royer V., Eliaers F., Ninane N., Carrard G., Friguet B., de Longueville F., Boffe S., Remacle J., Toussaint O. Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-β1 signaling pathway. J. Cell Sci. 2005, 118:743-758.
9. Distler J.H., Akhmetshina A., Schett G., Distler O. Monocyte chemoattractant proteins in the pathogenesis of systemic sclerosis. Rheumatology 2009, 48(2):98-103.
10. Fisher G.J., Datta S.C., Talwar H.S., Wang Z.Q., Varani J., Kang S., Voorhees J.J. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature 1996, 379:335-339.
11. Fisher G.J., Wang Z.Q., Datta S.C., Varani J., Kang S., Voorhees J.J. Pathophysiology of premature skin aging induced by ultraviolet light. N Eng. J. Med. 1997, 337:1419-1428.
12. Fisher G.J., Voorhees J.J. 1Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce Ap-1-regulated matrix metalloproteinases that degrade human skin in vivo. J. Invest. Dermatol. Symp. Proc. 1998, 3:61-68.
13. Fisher G., Datta S., Wang Z., Li X., Quan T., Chung J., Kang S., Voorhees J.J. c-jun-dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid. J Clin. Invest. 2000, 106:661-668.
14. Froberg M.K., Adams A., Seacotte N., Parker-Thornburg J., Kolattukudy P. Cytomegalovirus infection accelerates inflammation in vascular tissue overexpressing monocyte chemoattractant protein-1. Circ. Res. 2001, 89:1224-1230.
15. Galindo M., Santiago B., Rivero M., Rullas J., Alcami J., Pablos J.L. Chemokine expression by systemic sclerosis fibroblasts: abnormal regulation of monocyte chemoattractant protein 1 expression. Arthritis Rheum. 2001, 44:1382-6138.
16. Kang J.S., Kim H.N., Jung da J., Kim J.E., Mun G.H., Kim Y.S., Cho D., Shin D.H., Hwang Y.I., Lee W.J. Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane. J. Invest. Dermatol. 2007, 127:698-706.
17. Kawakami T., Ihn H., Xu W., Smith E., LeRoy C., Trojanowska M. Increased expression of TGF-beta receptors by scleroderma fibroblasts: evidence for contribution of autocrine TGF-beta signaling to scleroderma phenotype. J. Invest. Dermatol. 1998, 110:47-51.
18. Kim K.W., Bai S.C., Koo J.W., Wang X., Kim S.-K. Effects of dietary Chlorella ellipsoidea supplementation on growth, blood characteristics, and whole-body composition in juvenile Japanese flounder Paralichthys olivaceus. J. World Aquacult. Soc. 2002, 33:425-431.
19. Kireeva M., Mo F.-E., Yang G., Lau L. Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion. Mol. Cell Biol. 1996, 16:1326-1334.
20. Lau L., Lam S.C.-T. The CCN family of angiogenic regulators: the integrin connection. Exp. Cell Res. 1999, 248:44-57.
21. Lee C., Choi H., Kim H., Kim D., Chang I., Moon H.T., Lee S., Oh W.K., Woo E. BiXavonoids isolated from Selaginella tamariscina regulate the expression of matrix metalloproteinase in human skin Wbroblasts. Bioorg. Med. Chem. 2008, 16:732-738.
22. Lee Y.R., Noh E.M., Jeong E.Y., Yun S.K., Jeong Y.J., Kim J.H., Kwon K.B., Kim B.S., Lee S.H., Park C.S., Kim J.S. Cordycepin inhibits UVB-induced matrix metalloproteinase expression by suppressing the NF-kappaB pathway in human dermal fibroblasts. Exp. Mol. Med. 2009, 41:548-554.
23. Leonard E.J., Yoshimura T. Human monocyte chemoattractant protein-1 (MCP-1). Immunol. Today 1990, 11:97-101.
24. Massague J. TGF-β signal transduction. Ann. Rev. Biochem. 1998, 67:753-791.
25. Massague J., Wotton D. Transcriptional control by the TGF-β Smad signaling system. EMBO J. 2000, 19:1745-1754.
26. Morita K., Matsueda T., Iida T., Hasegawa T. Chlorella accelerates dioxin excretion in rats. J. Nutr. 1999, 129:1731-1736.
27. Park J.Y., Cho H.Y., Kim J.K., Noh K., Yang J.R., Ahn J.M., Lee M.O., Song Y.S. Chlorella dichloromethane extract ameliorates NO production and iNOS expression through the down-regulation of NFκB activity mediated by suppressed oxidative stress in RAW 264.7 macrophages. Clin. Chim. Acta 2005, 351:185-196.
28. Perbal B., Brigstock D., Lau L. Report on the second international workshop in the CCN family of genes. Mol. Pathol. 2003, 56:80-85.
29. Philips N., McFadden K. Inhibition of transforming growth factor-beta and matrix metalloproteinases by estrogen, and prolactin in breast cancer cells. Cancer Lett. 2004, 206:63-68.
30. Philips N., Keller T., Hendrix C., Hamilton S., Arena R., Tuason M., Gonzalez S. Regulation of the extracellular matrix remodeling by lutein in dermal Wbroblasts, melanoma cells, and ultraviolet radiation exposed Wbroblasts. Arch. Dermatol. Res. 2007, 299:373-379.
31. Piek E., Heldin C.H., ten Dijke P. Specificity, diversity, and regulation in TGF-beta superfamily signaling. EMBO J. 1999, 13:2105-2124.
32. Quan T., He T., Voorhees J.J., Fisher G.J. Ultraviolet irradiation blocks cellular responses to transforming growth factor-b by down-regulating its type-II receptor and inducing Smad7. J. Biol. Chem. 2001, 276:26349-26356.
33. Quan T., He T., Kang S., Voorhees J.J., Fisher G.J. Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-β type II receptor/Smad signaling. Am. J. Pathol. 2004, 165:741-751.
34. Quan T., He T., Voorhees J.J., Fisher G.J. Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts. J. Biol. Chem. 2005, 280:8079-8085.
35. Quan T., He T., Kang S., Voorhees J.J., Fisher G.J. Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin. Am. J. Pathol. 2006, 169:482-490.
36. Sheih I.C., Fang T.J., Wu T.K., Lin P.H. Anticancer and antioxidant activities of the peptide fraction from algae protein waste. J. Agric. Food Chem. 2010, 58:1202-1207.
37. Shih M.F., Cherng J.Y. Potential protective effect of fresh grown unicellular green algae component (resilient factor) against PMA- and UVB-induced MMP1 expression in skin fibroblasts. Eur. J. Dermatol. 2008, 18:303-307.
38. Shih M.F. Alleviatory effects of Chlorella-derived polypeptides against UVB-induced MMP-1 expression and extracellular matrix degradation in human skin fibroblast cells. Toxicol. Lett. 2010, 196S:S247.
39. 2 accumulation by catalase reduction changes MAP kinase signaling in aged human skin in vivo. J. Invest. Dermatol. 2005, 125:221-229.
40. Simon M.M., Aragane Y., Schwarz A., Luger T.A., Schwarz T. UVB light induces nuclear factor kappa B (NF kappa B) activity independently from chromosomal DNA damage in cell-free cytosolic extracts. J. Invest. Dermatol. 1994, 102:422-427.
41. Standiford T., Kunkel S.L., Phan S.H., Rollins R.J., Strieter R.M. Alveolar macrophage-derived cytokines induce monocyte chemoattractant protein-1 expression from human pulmonary type II-like epithelial cells. J. Biol. Chem. 1991, 266:9912-9918.
42. Suárez E.R., Kralovec J.A., Grindley T.B. Isolation of phosphorylated polysaccharides from algae: the immunostimulatory principle of Chlorella pyrenoidosa. Carbohydr. Res. 2010, 345:1190-1204.
43. Tanaka K., Yamada A., Nada K., Shoyama Y., Kubo C., Nomoto K. Oral administration of a unicellular green algae, Chlorella vulgaris, prevents stress-induced ulcer. Planta Med. 1997, 63:465-466.
44. Takamiya M., Biwasaka H., Saigusa K., Nakayashiki N., Aoki Y. Wound age estimation by simultaneous detection of 9 cytokines in human dermal wounds with a multiplex bead-based immunoassay: an estimative method using outsourced examinations. Leg. Med. (Tokyo) 2009, 11(4):186-190.
45. Tsoyi K., Park H.B., Kim Y.M., Chung J.I., Shin S.C., Lee W.S., Seo H.G., Lee J.H., Chang K.C., Kim H.J. Anthocyanins from black soybean seed coats inhibit UVB-induced inflammatory cylooxygenase-2 gene expression and PGE2 production through regulation of the nuclear factor-κB and phosphatidylinositol 3-kinase/Akt pathway. J. Agric. Food Chem. 2008, 56:8969-8974.
46. Valente A.J., Graves D.T., Vialle-Valentin C., Delgado R., Schwartz C.J. Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture. Biochemistry 1988, 27:4162-4168.
47. Watanabe H., Shimizu T., Nishihira J., Abe R., Nakayama T., Taniguchi M., Sabe H., Ishibashi T., Shimizu H. Ultraviolet A-induced production of matrix metalloproteinase-1 is mediated by macrophage migration inhibitory factor (MIF) in human dermal fibroblasts. J. Biol. Chem. 2004, 279:1676-1683.
48. Xia X., Park E., Liu B., Willette-Brown J., Gong W., Wang J., Mitchell D., Fischer S.M., Hu Y. Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis. Am. J. Pathol. 2010, 176:2500-2508.
49. Yamamoto T., Eckes B., Mauch C., Hartmann K., Krieg T. Monocyte chemoattractant protein-1 enhances gene expression and synthesis of matrix metalloproteinase-1 in human fibroblasts by an autocrine IL-1 alpha loop. J. Immunol. 2000, 164:6174-6179.
50. Yoshimura T., Leonard E.J. Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE. J. Immunol. 1990, 144:2377-2383.
51. Yoshimura T., Robinson E.A., Tanaka S., Appella S., Leonard E.J. Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J. Immunol. 1989, 142:1956-1962.
52. Yoshimura T., Takeya M., Takahashi K. Molecular cloning of rat monocyte chemoattractant protein-1 (MCP-1) and its expression in rat spleen cells and tumor cell lines. Biochem. Biophys. Res. Commun. 1991, 174:504-509.