Kidney preservation by bone marrow cell transplantation in hereditary nephropathy

Kidney International

Volumn 79, Issue 11, 2011, Pages 1198-1206

  Yeagy, Brian A ^a   Harrison, Frank ^a   Gubler, Marie Claire ^b   Koziol, James A ^a   Salomon, Daniel R ^a   Cherqui, Stephanie ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b INSERM   (France)

Author keywords

bone marrow stem cells; chronic kidney injury; cystinosis; donor derived blood cell engraftment

Indexed keywords

CYSTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; CYSTINOSIS; CYSTINOSIS GENE; ENGRAFTMENT; GENE; GENE EXPRESSION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOPATHOLOGY; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY PRESERVATION; KIDNEY TUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RENAL PROTECTION; THERAPY EFFECT; TISSUE LEVEL;

EID: 79955991844     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2010.537     Document Type: Article

References (36)

1. Consortium CKDP. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet 2010; 375: 2073-2081.
2. Black C, Sharma P, Scotland G et al. Early referral strategies for management of people with markers of renal disease: a systematic review of the evidence of clinical effectiveness, cost-effectiveness and economic analysis. Health Technol Assess 2010; 14: 1-184.
3. Cerasola G, Nardi E, Palermo A et al. Epidemiology and pathophysiology of left ventricular abnormalities in chronic kidney disease: a review. J Nephrol 2010; 24: 1-10.
4. Cantley LG. Adult stem cells in the repair of the injured renal tubule. Nat Clin Pract Nephrol 2005; 1: 22-32.
5. De Broe ME. Tubular regeneration and the role of bone marrow cells: 'stem cell therapy'-a panacea? Nephrol Dial Transplant 2005; 20: 2318-2320. (Pubitemid 41548854)
6. Masereeuw R. Contribution of bone marrow-derived cells in renal repair after acute kidney injury. Minerva Urol Nefrol 2009; 61: 373-384.
7. Fang TC, Alison MR, Cook HT et al. Proliferation of bone marrow-derived cells contributes to regeneration after folic acid-induced acute tubular injury. J Am Soc Nephrol 2005; 16: 1723-1732. (Pubitemid 41716478)
8. Fang TC, Otto WR, Rao J et al. Haematopoietic lineage-committed bone marrow cells, but not cloned cultured mesenchymal stem cells, contribute to regeneration of renal tubular epithelium after HgCl 2-induced acute tubular injury. Cell Prolif 2008; 41: 575-591.
9. Li B, Cohen A, Hudson TE et al. Mobilized human hematopoietic stem/ progenitor cells promote kidney repair after ischemia/reperfusion injury. Circulation 2010; 121: 2211-2220.
10. LeBleu V, Sugimoto H, Mundel TM et al. Stem cell therapies benefit Alport syndrome. J Am Soc Nephrol 2009; 20: 2359-2370.
11. Sugimoto H, Mundel TM, Sund M et al. Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. Proc Natl Acad Sci USA 2006; 103: 7321-7326. (Pubitemid 43727831)
12. Lin F, Moran A, Igarashi P. Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J Clin Invest 2005; 115: 1756-1764. (Pubitemid 40979714)
13. Duffield JS, Park KM, Hsiao LL et al. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest 2005; 115: 1743-1755. (Pubitemid 40979713)
14. Szczypka MS, Westover AJ, Clouthier SG et al. Rare incorporation of bone marrow-derived cells into kidney after folic acid-induced injury. Stem Cells 2005; 23: 44-54. (Pubitemid 40105290)
15. Stokman G, Leemans JC, Claessen N et al. Hematopoietic stem cell mobilization therapy accelerates recovery of renal function independent of stem cell contribution. J Am Soc Nephrol 2005; 16: 1684-1692. (Pubitemid 41716474)
16. Stokman G, Leemans JC, Stroo I et al. Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis. Nephrol Dial Transplant 2008; 23: 483-491. (Pubitemid 351767621)
17. Cherqui S, Sevin C, Hamard G et al. Intralysosomal cystine accumulation in mice lacking cystinosin, the protein defective in cystinosis. Mol Cell Biol 2002; 22: 7622-7632.
18. Nevo N, Chol M, Bailleux A et al. Renal phenotype of the cystinosis mouse model is dependent upon genetic background. Nephrol Dial Transplant 2009; 25: 1059-1066.
19. Syres K, Harrison F, Tadlock M et al. Successful treatment of the murine model of cystinosis using bone marrow cell transplantation. Blood 2009; 114: 2542-2552.
20. Baer PC, Geiger H. Mesenchymal stem cell interactions with growth factors on kidney repair. Curr Opin Nephrol Hypertens 2010; 19: 1-6.
21. Kunter U, Rong S, Djuric Z et al. Transplanted mesenchymal stem cells accelerate glomerular healing in experimental glomerulonephritis. J Am Soc Nephrol 2006; 17: 2202-2212. (Pubitemid 44141910)
22. Togel F, Cohen A, Zhang P et al. Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev 2009; 18: 475-485.
23. Fang TC, Otto WR, Jeffery R et al. Exogenous bone marrow cells do not rescue non-irradiated mice from acute renal tubular damage caused by HgCl2, despite establishment of chimaerism and cell proliferation in bone marrow and spleen. Cell Proliferat 2008; 41: 592-606.
24. St-Louis M, Tanguay RM. Mutations in the fumarylacetoacetate hydrolase gene causing hereditary tyrosinemia type I: overview. Hum Mutat 1997; 9: 291-299. (Pubitemid 27157647)
25. Grompe M. The pathophysiology and treatment of hereditary tyrosinemia type 1. Semin Liver Dis 2001; 21: 563-571. (Pubitemid 33131048)
26. Grompe M, Lindstedt S, al-Dhalimy M et al. Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I. Nat Genet 1995; 10: 453-460.
27. Held PK, Al-Dhalimy M, Willenbring H et al. In vivo genetic selection of renal proximal tubules. Mol Ther 2006; 13: 49-58. (Pubitemid 41763482)
28. Thoene JG. Lysosomal cystine augments apoptosis and causes the phenotype in cystinosis. Beijing Da Xue Xue Bao 2005; 37: 8-9.
29. Thoene JG. A review of the role of enhanced apoptosis in the pathophysiology of cystinosis. Mol Genet Metab 2007; 92: 292-298. (Pubitemid 350117712)
30. Chol M, Nevo N, Cherqui S et al. Glutathione precursors replenish decreased glutathione pool in cystinotic cell lines. Biochem Biophys Res Commun 2004; 324: 231-235. (Pubitemid 39311483)
31. Coor C, Salmon RF, Quigley R et al. Role of adenosine triphosphate (ATP) and NaK ATPase in the inhibition of proximal tubule transport with intracellular cystine loading. J Clin Invest 1991; 87: 955-961.
32. Foreman JW, Benson LL, Wellons M et al. Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis. J Am Soc Nephrol 1995; 6: 269-272.
33. Sakarcan A. The Fanconi syndrome of cystinosis: insights into the pathophysiology. Turk J Pediatr 2002; 44: 279-282. (Pubitemid 35314701)
34. Gahl WA, Thoene J, Schneider JA. Cystinosis: a disorder of lysosomal membrane transport. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds). The Metabolic and Molecular Bases of Inherited Disease, 8th edn, vol. 3, McGraw Hill: New York, 2001, pp 5085-5108.
35. Kim MG, Boo CS, Ko YS et al. Depletion of kidney CD11c+ F4/80+ cells impairs the recovery process in ischaemia/reperfusion-induced acute kidney injury. Nephrol Dial Transplant 2010; 25: 2908-2921.
36. Fujigaki Y, Muranaka Y, Sun D et al. Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate-induced acute renal failure in rats. Virchows Arch 2005; 446: 164-176. (Pubitemid 40385647)