Cocrystallization via planetary milling: Enhancing throughput of solid-state screening methods

International Journal of Pharmaceutics

Volumn 411, Issue 1-2, 2011, Pages 169-171

  Bysouth, Stephen R ^a   Bis, Joanna A ^b   Igo, David ^b  

^a Automaxion SARL   (France)

^b CATALENT PHARMA SOLUTIONS   (United States)

Author keywords

Automation; Cocrystal; Grinding; High throughput; Mechanochemical; Milling; Screening; SDG; Solvent drop

Indexed keywords

CAFFEINE; CARBAMAZEPINE; MALEIC ACID; OXALIC ACID; SACCHARIN;

ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; DRUG MIXTURE; PHASE SEPARATION; PLANETARY MILLING; PRIORITY JOURNAL; RAMAN SPECTROMETRY;

CRYSTALLIZATION; DRUG COMPOUNDING; EQUIPMENT AND SUPPLIES; EXCIPIENTS; HIGH-THROUGHPUT SCREENING ASSAYS; PHARMACEUTICAL PREPARATIONS; POWDERS;

EID: 79955977309     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.037     Document Type: Article

References (19)

1. Berry, D.J., Seaton, C.C., Clegg, W., Harrington, R.W., Coles, S.J., Horton, P.N., Hursthouse, M.B., Storey, R., Jones, W., Fri, T., Blagden, N., 2008. Applying hot-stage microscopy to co-crystal screening: a study of nicotinamide with seven active pharmaceutical ingredients. Cryst. Growth Des. 8, 1697-1712.
2. Bis, J.A., Vishweshwar, P., Weyna, D., Zaworotko, M.J., 2007. Hierarchy of supramolecular synthons: persistent hydroxyl pyridine hydrogen bonds in cocrystals that contain a cyano acceptor. Mol. Pharm. 4, 401-416.
3. Bysouth, S.R., 2006. PCT Int Appl.WO2006086567.
4. Bysouth, S.R., 2008. USPat. 7, 448-566.
5. Bysouth, S.R., Hite III, S.W., Nettleton-Hammond, J.H., Bergstrom, K.I, Bohara, A, Landham, R.R., and Lukkari, I.G., 2009. US Pat, 7, 501-094.
6. Childs, S.L., Rodríguez-Hornedo, N., Reddy, L.S., Jayasankar, A., Maheshwari, C., McCausland, L., Shipplett, R., Stahly, B.C., 2008. Screening strategies based on solubility and solution composition generate pharmaceutically acceptable cocrystals of carbamazepine. CrystEngComm 10, 856-864.
7. Friščić, T., Childs, S.L., Rizvi, S.A., Jones, W., 2009. The role of solvent in mechanochemical and sonochemical cocrystal formation: a solubility-based approach for predicting cocrystallisation outcome. CrystEngComm 11, 418-426.
8. Jayasankar, A., Good, D.J., Rodríguez-Hornedo, N., 2007. Mechanisms by which moisture generates cocrystals. Mol. Pharm. 4, 360-372.
9. Kojima, T., Tsutsumi, T., Yamamoto, K., Ikeda, Y., Moriwaki, T., 2010. High-throughput cocrystal slurry screening by use of in situ Raman microscopy and multi-well plate. Int. J. Pharm. 399, 52-59.
10. Maheshwari, C., Jayasankar, A., Khan, N.A., Amidon, G.E., Rodríguez-Hornedo, N., 2009. Factors that influence the spontaneous formation of pharmaceutical cocrystals by simply mixing solid reactants. CrystEngComm 11, 493-500.
11. Padrela, L., Rodrigues, M.A., Velaga, S.P., Matos, H.A., Gomes de Azevedo, E., 2009. Formation of indomethacin-saccharin cocrystals using supercritical fluid technology. Eur. J. Pharm. Sci. 38, 9-17.
12. Porter III, W.W., Elie, S.C., Matzger, A.J., 2008. Polymorphism in carbamazepine cocrystals. Cryst. Growth Des. 8, 14-16.
13. Schultheiss, N., Newman, A., 2009. Pharmaceutical cocrystals and their physicochemical properties. Cryst. Growth Des. 9, 2950-2967.
14. Shan, N., Toda, F., Jones, W., 2002. Mechanochemistry and co-crystal formation: effect of solvent on reaction kinetics. Chem. Commun. 20, 2372-2373.
15. Trask, A.W., Motherwell, S.W.D., Jones, W., 2005. Pharmaceutical cocrystallization: engineering a remedy for caffeine hydration. Cryst. Growth Des. 5, 1013-1021.
16. Trask, A.V., Haynes, D.A., Motherwell, S.W.D., Jones, W., 2006. Screening for crystalline salts via mechanochemistry. Chem. Commun., 51-53.
17. Vishweshwar, P., McMahon, J.A., Bis, J.A., Zaworotko, M.J., 2006. Pharmaceutical cocrystals. J. Pharm. Sci. 95, 499-516.
18. Weyna, D.R., Shattock, T., Vishweshwar, P., Zaworotko, M.J., 2009. Synthesis and structural characterization of cocrystals and pharmaceutical cocrystals: mechanochemistry vs slow evaporation from solution. Cryst. Growth Des. 9, 1106-1123.
19. Zhang, G.G., Henry, R.F., Borchardt, T.B., Lou, X., 2007. Efficient co-crystal screening using solution-mediated phase transformation. J. Pharm. Sci. 96, 990-995.