Targeted ultrasound contrast imaging of matrix metalloproteinase-2 in ischemia-reperfusion rat model: Ex vivo and in vivo studies

Molecular Imaging and Biology

Volumn 13, Issue 2, 2011, Pages 293-302

  Su, Haili ^a   Du, Yongfeng ^b   Qian, Yunqiu ^a   Zong, Yujin ^c   Li, Jun ^a   Zhuang, Ran ^d   He, Jianguo ^a   Wei, Zhangrui ^a   Zhang, Jun ^a   Zhou, Xiaodong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b XI'AN UNIVERSITY OF TECHNOLOGY   (China)

^c XI'AN JIAOTONG UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Left ventricular remodeling; Metalloproteinases 2; Myocardial ischemia reperfusion; Targeted microbubble

Indexed keywords

GELATINASE A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC IMAGING; CONTRAST ENHANCEMENT; CONTROLLED STUDY; ECHOCARDIOGRAPHY; EX VIVO STUDY; FEMALE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART VENTRICLE REMODELING; IMAGE ANALYSIS; IMAGE PROCESSING; IMAGE QUALITY; IN VIVO STUDY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MEMBRANE PERMEABILITY; MICROBUBBLE; MOLECULAR IMAGING; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; REPERFUSION INJURY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; CAPILLARY PERMEABILITY; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; MALE; MATRIX METALLOPROTEINASE 2; MICROBUBBLES; MICROVESSELS; MOLECULAR IMAGING; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; ULTRASONICS; VENTRICULAR FUNCTION, LEFT;

RATTUS;

EID: 79955930809     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-010-0350-9     Document Type: Article

References (33)

1. Gaudron P, Eilles C, Kugler I et al (1993) Progressive left ventricular dysfunction and remodeling after myocardial infarction: potential mechanisms and early predictors. Circulation 87:755-763 (Pubitemid 23070806)
2. Pfeffer MA, Braunwald E (1990) Ventricular remodeling after myocardial infarction: experimental observations and clinical implications. Circulation 81:1161-1172 (Pubitemid 20119612)
3. Roberts CS, Maclean D, Maroko P et al (1984) Early and late remodeling of the left ventricle after acute myocardial infarction. Am J Cardiol 54:407-410 (Pubitemid 14055772)
4. Creemers EE, Davis JN, Parkhurst AM et al (2003) Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice. Am J Physiol Heart Circ Physiol 284:H364-H371 (Pubitemid 36076305)
5. Ducharme A, Frantz S, Aikawa M et al (2000) Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest 106:55-62 (Pubitemid 30437240)
6. Mukherjee R, Brinsa TA, Dowdy KB et al (2003) Myocardial infarct expansion and matrix metalloproteinase inhibition. Circulation 107:618-625 (Pubitemid 36176814)
7. Massova I, Kotra LP, Fridman R et al (1998) Matrix metalloproteinases: structures, evolution, and diversification. FASEB J 12:1075-1095 (Pubitemid 28418938)
8. Wang W, Schulze CJ, Suarez-Pinson WL et al (2002) Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation 106:1543-1549
9. Su H, Spinale FG et al (2005) Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling. Circulation 112:3157-3167
10. Kaufmann BA, Lindner JR (2007) Molecular imaging with targeted contrast ultrasound. Curr Opin Biotechnol 18:11-16 (Pubitemid 46237740)
11. Unger EC, McCreery TP, Sweitzer RH et al (1998) In vitro studies of a new thrombus-specific ultrasound contrast agent. Am J Cardiol 81:58G-61G
12. Lindner JR, Song J, Christiansen J et al (2001) Ultrasound assessment of inflammation and renal tissue injury with microbubbles targeted to P-selectin. Circulation 104:2107-2112 (Pubitemid 33027054)
13. Weller GER, Lu E, Csikari MM et al (2003) Ultrasound imaging of acute cardiac transplant rejection with microbubbles targeted to intercellular adhesion molecule-1. Circulation 108:218-224 (Pubitemid 36871306)
14. Schumann PA, Christiansen JP, Quigley RM et al (2002) Targeted-microbubble binding selectively to GPIIb/IIIa receptors of platelet thrombi. Invest Radiol 37:587-593 (Pubitemid 35231692)
15. Leong-Poi H, Christiansen J, Klibanov AL et al (2003) Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted to alphav-integrins. Circulation 107:455-460 (Pubitemid 36158049)
16. Weller GER, Wong MKK, Modzelewski RA et al (2005) Ultrasonic imaging of tumor angiogenesis using contrastmicrobubbles targeted via the tumor-binding peptide arginine-arginine-leucine. Cancer Res 65:533-539
17. Swanson SD, Dou C, Miller DL (2006) Magnetic resonance imaging of microvascular leakage induced by myocardial contrast echocardiography in rats. Magn Reson Imaging 24:603-609 (Pubitemid 43776560)
18. Chen S, Shohet RV, Bekeredjian R et al (2003) Optimization of ultrasound parameters for cardiac gene delivery of adenoviral or plasmid deoxyribonucleic acid by ultrasound-targeted MB destruction. JACC 42(2):301-308 (Pubitemid 36851422)
19. Miller D, Li P, Armstrong WF (2004) The effect of time and of vasoactive drugs on capillary leakage induced during myocardial contrast echocardiography. Echocardiography 21:125-132 (Pubitemid 38280959)
20. Skyba DM, Price RJ, Linka AZ et al (1998) Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue. Circulation 98:290-293 (Pubitemid 28348049)
21. Price RJ, Skyba DM, Kaul S et al (1998) Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound. Circulation 98:1264-1267 (Pubitemid 28443388)
22. Kaufmann BA, Lewis C, Xie A et al (2007) Detection of recent myocardial ischaemia by molecular imaging of P-selectin with targeted contrast echocardiography. Eur Heart J 28(16):2011-2017
23. Lindner JR, Dayton PA, Coggins MP et al (2000) Non-invasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles. Circulation 102:531-538
24. Wei K, Jayaweera AR, Firoozan S et al (1998) Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation 97:473-483
25. Wei K, Jayaweera AR, Firoozan S, Linka A, Skyba DM, Kaul S (1998) Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation 97:473-483
26. Wilson EM, Moainie SL, Baskin JM et al (2003) Region- and type-specific induction of matrix metalloproteinases in post-myocardial infarction remodeling. Circulation 107:2857-2863
27. Yarbrough WM, Mukherjee R, Escobar GP et al (2003) Selective targeting and timing of matrix metalloproteinase inhibition in postmyocardial infarction remodeling. Circulation 108:1753-1759
28. Klibanov AL (1999) Targeted delivery of gas-filled microspheres, contrast agents for ultrasound imaging. Adv Drug Deliv Rev 37(1-3):139-157
29. Miller DL, Pislaru SV, Greenleaf JE (2002) Sonoporation: mechanical DNA delivery by ultrasonic cavitation. Somat Cell Mol Genet 27(1-6):115-134
30. Lindner JR, Kaul S (2001) Delivery of drugs with ultrasound. Echocardiography 18(4):329-337
31. Mizushige K, Kondo I, Ohmori K et al (1999) Enhancement of ultrasound-accelerated thrombolysis by echo contrast agents: dependence on microbubble structure. Ultrasound Med Biol 25(9):1431-1437
32. Miller DL, Li P, Gordon D et al (2005) Histological characterization of microlesions induced by myocardial contrast echocardiography. Echocardiography 22(1):25-34
33. Shohet RV, Chen S, Zhou YT et al (2000) Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium. Circulation 101:2554-2556