Screening of substrate peptide sequences for tissue-type transglutaminase (TGase 2) using T7 phage cDNA library

Cytotechnology

Volumn 63, Issue 2, 2011, Pages 111-118

  Sugimura, Yoshiaki ^a   Yamashita, Hiroyuki ^a   Hitomi, Kiyotaka ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Calcium; cDNA library; IKAP; T7 phage; Transglutaminase

Indexed keywords

AVIDIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2;

BACTERIOPHAGE T7; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; DNA LIBRARY; DNA SCREENING; DNA SEQUENCE; GENETIC CODE; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

MAMMALIA;

EID: 79955922896     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-010-9308-7     Document Type: Conference Paper

References (26)

1. Anderson SL, Coli R, Daly IW, Kichula EA, Rork MJ, Volpi SA, Ekstein J, Rubin BY (2001) Familial dysautonomia is caused by mutation of the IKAP gene. Am J Hum Genet 68:753-758 (Pubitemid 32202767)
2. Chen Y-T, Hims MM, Shetty RS, Mull J, Liu L, Leyne M, Slaugenhaupt SA (2009) Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKAKAP. Mol Cell Biol 29:736-744
3. Cohen L, Henzel WJ, Baeuerie PA (1998) IKAP is a scaffold protein of the IkB kinase complex. Nature 395:292-296 (Pubitemid 28447556)
4. Csosz E, Mesko B, Fésüs L (2009) Transdab wiki: the interactive transglutaminase substrate database on web 2.0 surface. Amino Acids 36:615-617
5. Eckert RL, Sturniolo MT, Broome AM, Ruse M, Rorke EA (2005) Transglutaminase function in epidermis. J Invest Dermatol 124:481-492 (Pubitemid 40381569)
6. Esposito C, Caputo I (2005) Mammalian transglutaminases: identification of substrates as a key to physiological function and physiological relevance. FEBS J 272:615-631 (Pubitemid 40208867)
7. Facchiano A, Facchiano F (2009) Transglutaminases and their substrates in biology and human diseases: 50 years of growing. Amino Acids 36:599-614
8. Fésüs L, Piacentini M (2002) Transglutaminase 2: an enigmatic enzyme with diverstic functions. Trends Biochem Sci 27:534-539 (Pubitemid 35279599)
9. Griffin M, Casadio R, Bergamini CM (2002) Transglutaminases: nature's biological glues. Biochem J 368:377-396 (Pubitemid 35454517)
10. Hitomi K (2005) Transglutaminase in skin epidermis. Eur J Dermatol 15:313-319
11. Hitomi K, Kitamura M, Sugimura Y (2009) Preferred substrate sequences for transglutaminase 2: screening using a phage-displayed peptide library. Amino Acids 36:619-624
12. Ichikawa A, Ishizaki J, Morita M, Tanaka K, Ikura K (2008) Identification of new amine acceptor protein substrate candidate of transglutaminase in rat liver extract: use of 5-(biotinamido)pentylamine as a probe. Biosci Biotechnol Biochem 72:1056-1062 (Pubitemid 351679359)
13. Ichinose A (2001) Physiopathology and regulation of factor XIII. Thromb Haemost 86:57-65
14. Ikura K, Kita K, Fujita I, Hashimoto H, Kawabata N (1998) Idetification of amine acceptor protein substrates of transglutaminase in liver extracts: use of 5-(biotinamido)pentylamine as a probe. Arch Biochem Biophys 356:280-286 (Pubitemid 28387732)
15. Jeitner TM, Pinto JT, Krasnikov BF, Horswill M, Cooper AJL (2009) Transglutaminase and neurogeneration. J Neurochem 109(1):160-166
16. Johansen LD, Naumanen T, Knudsen A, Westerlund N, Gromova I, Junttilla M, Nielsen C, Bottzauw T, Tolkovsky A, Wastermarck J, Coffey ET, Jaattela M, Kallunki T (2008) IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration. J Cell Sci 121:854-864 (Pubitemid 351578121)
17. Keresztessy Z, Csosz É, Hársfalvi J, Csomós K, Gray J, Lightowlers RN, Lakey JH, Balajthy Z, Fésüs L (2006) Phage display selection of efficient glutamine-donor substrate peptides for transglutaminase 2. Protein Sci 15:2466-2480 (Pubitemid 44771684)
18. Lee KN, Maxwell MD, Patterson MK, Birckbichler PJ, Conway E (1992) Identification of transglutaminase substrates in HT29 colon cancer cells: use of 5-(biotinamido)-pentylamine as a transglutaminase-specific probe. Biochim Biophys Acta 1136:12-16
19. Lorand L, Graham RM (2003) Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 4:140-156 (Pubitemid 36172696)
20. Morohashi K, Yoshino A, Yoshimori A, Saito S, Tanuma S, Sakaguchi K, Sugawara F (2005) Identification of a drug target motif: an anti-tumor drug NK109 interacts with a PNxxxxP. Biochem Pharmacol 70:37-46 (Pubitemid 40797869)
21. Orru S, Caputo I, D'Amato A, Ruoppolo M, Esposito C (2003) Proteomics identification of acyl-acceptor and acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line. J Biol Chem 278:31766-31773 (Pubitemid 37048357)
22. Slaugenhaupt SA, Blumenfeld A, Gill SP, Leyne M, Mull J, Cuajungco MP, Liebert CB, Chadwick B, Idelson M, Reznik L, Robbins CM, Makalowska I, Brownstein M, Krappman D, Scheidereit C, Maayan C, Axelrod FB, Gusella JF (2001) Tissue-specific expression of a splicing mutation in the IKABKAP gene causes familial dysautonomia. Am J Hum Genet 68:598-605 (Pubitemid 32202755)
23. Sollid LM (2002) Coeliac disease: dissecting a complex inflammatory disorder. Nat Rev Immunol 2:647-655
24. Sugimura Y, Hosono M, Wada F, Yoshimura T, Maki M, Hitomi K (2006) Screening for the preferred substrate sequence of transglutaminase using a phage-displayed peptide library: identification of peptide substrates for TGase 2 and factor XIIIa. J Biol Chem 281:17699-17706 (Pubitemid 44035568)
25. Sugimura Y, Hosono M, Kitamura M, Tsuda T, Yamanishi K, Maki M, Hitomi K (2008a) Identification of preferred substrate sequences for transglutaminase 1-development of a novel peptide that can efficiently detect cross-linking enzyme activity in the skin. FEBS J 275:5667-5677
26. Sugimura Y, Yokoyma K, Nio N, Maki M, Hitomi K (2008b) Identification of preferred substrate sequences of microbial transglutaminase from Streptomyces mobaraensis using a phage-displayed peptide library. Arch Biochem Biophys 477:379-383