The amyloid formation mechanism in human IAPP: Dimers have β-strand monomer-monomer interfaces

Journal of the American Chemical Society

Volumn 133, Issue 19, 2011, Pages 7240-7243

  Dupuis, Nicholas F ^a   Wu, Chun ^a   Shea, Joan Emma ^a   Bowers, Michael T ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FORMATION; ASSEMBLY MECHANISM; CONVENTIONAL TECHNIQUES; EXPERIMENTAL DATA; INHIBITION EFFECT; MOLECULAR DYNAMICS SIMULATIONS; MONOMER-MONOMER INTERFACES; MUTATION EFFECTS; N-METHYLATION; N-TERMINALS; PATHOLOGICAL PROCESS; SELF-INTERACTIONS; TYPE II;

ALKYLATION; CELL DEATH; MOLECULAR DYNAMICS; MONOMERS; OLIGOMERIZATION;

DIMERS;

AMYLIN; AMYLOID; DIMER;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; METHYLATION; OLIGOMERIZATION; PANCREAS ISLET BETA CELL; SIMULATION;

ANIMALS; HUMANS; ISLET AMYLOID POLYPEPTIDE; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RATS; SURFACE PROPERTIES;

EID: 79955896407     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1081537     Document Type: Article

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