Understanding the physical basis of the salt dependence of the electrostatic binding free energy of mutated charged ligand-nucleic acid complexes

Biophysical Chemistry

Volumn 156, Issue 1, 2011, Pages 79-87

  Harris, Robert C ^a   Bredenberg, Johan H ^a   Silalahi, Alexander R J ^a   Boschitsch, Alexander H ^b   Fenley, Marcia O ^a  

^a Florida State University   (United States)

^b Continuum Dynamics Inc ^*  (United States)

Author keywords

Binding; Counterion condensation theory; Debye H ckel equation; Electrostatics; Generalized Born model; Poisson Boltzmann equation

Indexed keywords

ARTICLE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); DEBYE HUCKEL EQUATION; DNA BINDING MOTIF; GENE MUTATION; GENERALIZED BORN MODEL; MATHEMATICAL PARAMETERS; OSMOTIC PRESSURE; POISSON BOLTZMANN EQUATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN RNA BINDING; SALT CONCENTRATION; STATIC ELECTRICITY;

ANIMALS; DATABASES, PROTEIN; HUMANS; LIGANDS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTATION; PROTEINS; RNA; SALTS; STATIC ELECTRICITY; THERMODYNAMICS;

EID: 79955888291     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2011.02.010     Document Type: Article

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