Vagal Innervation and Early Postoperative Ileus in Mice

Journal of Gastrointestinal Surgery

Volumn 15, Issue 6, 2011, Pages 891-901

  Mueller, Mario H ^a   Karpitschka, Martina ^a   Gao, Zhirong ^a,b   Mittler, Sarah ^a   Kasparek, Michael S ^a   Renz, Bernhard ^a   Sibaev, Andrej ^a   Glatzle, Jörg ^c   Li, Yongyu ^b   Kreis, Martin E ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b TONGJI UNIVERSITY   (China)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Immune response; Postoperative ileus; Sensitivity; Vagus

Indexed keywords

SEROTONIN;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; C57BL MOUSE; DRUG EFFECT; GASTROINTESTINAL MOTILITY; ILEUS; INNERVATION; JEJUNUM; LAPAROTOMY; LEUKOCYTE COUNT; MALE; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; POSTOPERATIVE COMPLICATION; SENSORY NERVE; TIME; VAGOTOMY; VAGUS NERVE;

AFFERENT PATHWAYS; ANALYSIS OF VARIANCE; ANIMALS; GASTROINTESTINAL MOTILITY; ILEUS; JEJUNUM; LAPAROTOMY; LEUKOCYTE COUNT; MALE; MICE; MICE, INBRED C57BL; POSTOPERATIVE COMPLICATIONS; SEROTONIN; TIME FACTORS; VAGOTOMY; VAGUS NERVE;

EID: 79955863944     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-011-1481-2     Document Type: Article

References (25)

1. Kreis ME, Kasparek MS, Becker HD, Jehle EC, Zittel TT. Postoperative ileus: part II (Clinical therapy). Zentralbl Chir 2003; 128: 320-8.
2. Kasparek MS, Kreis ME, Jehle EC, Zittel TT. Postoperative ileus: part I (Experimental results). Zentralbl Chir 2003; 128: 313-9.
3. Luckey A, Livingston E, TacheY. Mechanisms and treatment of postoperative ileus. Arch Surg 2003; 138: 206-14.
4. Bauer AJ, Boeckxstaens GE. Mechanisms of postoperative ileus. 2004; 16 Suppl. 2: 54-60.
5. Kreis ME, Kasparek M, Zittel TT, Becker HD, Jehle EC. Neostigmine increases postoperative colonic motility in patients undergoing colorectal surgery. Sugery 2001; 130: 449-58.
6. Schwarz NT, Kalff JC, Türler A, Engel BM, Watkins SC, Billiar TR, Bauer AJ. Prostanoid production via COX-2 as a causative mechanism of rodent postoperative ileus. Gastroenterology 2001; 121: 1354-71.
7. Pantelis D, Kabba MS, Kirfel J, Kahl P, Wehner S, Buettner R, Hirner A, Kalff JC. Transient perioperative pharmacologic inhibition of muscularis macrophages as a target for prophylaxis of postoperative ileus does not affect anastomotic healing in mice. Surgery 2010; 148: 59-70.
8. Zittel TT, Reddy SN, Plourde V, Raybould HE. Role of spinal afferents and calcitonin gene-related peptide in the postoperative gastric ileus in anesthetized rats. Ann Surg 1994; 219: 79-87.
9. Kalff JC, Schraut WH, Simmons RL, Bauer AJ. Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus. Ann Surg 1998; 28: 652-63.
10. Borovikova LV, Ivanova S, Zhang M, Botchkina GI, Watkins LR, Wang H, Abumrad N, Eaton JW, and Tracey KJ. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405: 458-462, 2000.
11. The FO, Boeckxstaens GE, Snoek SA, Cash JL, Bennink R, Larosa GJ, van den Wijngaard RM, Greaves DR, de Jonge WJ. Activation of the cholinergic anti-inflammtory pathway ameliorates postoperative ileus in mice. Gastroenterology 2007; 133: 1219-28.
12. Pavlov VA, Wang H, Czura CJ, Friedman SG, and Tracey KJ. The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation. Mol Med 2003; 9: 125-34.
13. Mueller MH, Karpitschka M, Xue B, Kasparek MS, Sibaev A, Glatyle J, Kreis ME. Intestinal afferent nerve sensitivity is increased during the initial development of postoperative ileus in mice. J Gastrointest Surg 2009; 13: 423-31.
14. Mueller MH, Glatzle J, Kampitoglou D, Kasparek MS, Grundy D, Kreis ME. Differential sensitization of afferent neuronal pathways during postoperative ileus in the mouse jejunum. Ann Surg 2008; 247: 791-802.
15. Boeckxstaens GE, de Jonge WJ. Neuroimmune mechanisms in postoperative ileus. Gut 2009; 58: 1300-11.
16. Liu CY, Mueller MH, Grundy D, Kreis ME. Vagal modulation of intestinal afferent sensitivity to systemic LPS in the rat. Am J Physiol Gastrointest Liver Physiol. 2007; 292: G1213-20.
17. Hillsley K, Grundy D. Sensitivity to 5-hydroxytryptamine in different afferent subpopulations within mesenteric nerves supplying the rat jejunum. J Physiol. 1998; 509: 717-27.
18. Hillsley K, Kirkup AJ, Grundy D. Direct and indirect actions of 5-hydroxytryptamine on the discharge of mesenteric afferent fibres innervating the rat jejunum. J Physiol. 1998; 506: 551-61.
19. Booth CE, Shaw J, Hicks GA, Kirkup AJ, Winchester W, Grundy D. Influence of the pattern of jejunal distension on mesenteric afferent sensitivity in the anaesthetized rat. Neurogastroenterol Motil 2008; 20: 149-58.
20. Brundsden AM, Grundy D. Sensitization of visceral afferents to bradykinin in rat jejunum in vitro. J Physiol 1999; 521: 517-527.
21. De Jonge WJ, The FO, van der Coelen, Bennink RJ, Reitsma PH, van Deventer SJ, van den Wijngaard RM, Boeckxstaens GE. Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice. Gastroenterology 2004; 127: 535-45.
22. Huge A, Kreis ME, Zittel TT, Becker HD, Starlinger MJ, Jehle EC. Postoperative colonic motility and tone in patients after colorectal surgery. Dis Colon Rectum 2000; 43: 932-9.
23. Maubach, KA, and Grundy D. The role of prostaglandins in the bradykinin-induced activation of serosal afferents of the rat jejunum in vitro. J Physiol (Lond) 1999; 515: 277-285.
24. Mueller MH, Kampitoglou D, Glatzle J, Hahn J, Kreis ME. Systemic capsaicin inhibits neuronal activation in the brainstem during postoperative ileus in the mouse. Langenbecks Arch Surg 2006; 391: 88-95.
25. Noble EJ, Harris R, Hosie KB, Thomas S, Lewis SJ (2009) Gum chewing reduces postoperative ileus? A systematic review and meta-analysis. Int J Surg 7: 100-5.