Visual cortex abnormalities in adults with ADHD: A structural MRI study

World Journal of Biological Psychiatry

Volumn 12, Issue 4, 2011, Pages 260-270

  Ahrendts, Johannes ^a   Rüsch, Nicolas ^a   Wilke, Marko ^b   Philipsen, Alexandra ^a   Eickhoff, Simon B ^c   Glauche, Volkmar ^a   Perlov, Evgeniy ^a   Ebert, Dieter ^a   Hennig, Jürgen ^a   Tebartz Van Elst, Ludger ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c UNIVERSITY OF AACHEN MEDICAL CENTER   (Germany)

Author keywords

Attention; attention defi cit hyperactivity disorder; MRI; occipital lobe; voxel based morphometry

Indexed keywords

ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; EXECUTIVE FUNCTION; FEMALE; GRAY MATTER; HUMAN; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTERIOR PARIETAL CORTEX; PREFRONTAL CORTEX; VISUAL CORTEX; VOXEL BASED MORPHOMETRY;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; ARTIFACTS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; VISUAL CORTEX; YOUNG ADULT;

EID: 79955844608     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622975.2010.518624     Document Type: Article

References (87)

1. Alexander GE, DeLong MR, Strick PL. 1986. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357-381. (Pubitemid 16055790)
2. American Psychiatric Association. 1994. Diagnostic and Statistical Manual of Mental Disorders. Washington, DC: American Psychiatric Press.
3. Ashburner J, Friston KJ. 2000. Voxel-based morphometry-the methods. Neuroimage 11:805-821.
4. Barkley RA. 1997. Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull 121:65-94. (Pubitemid 127705285)
5. Beck AT, Steer RA. 1987. Manual for the Revised Beck Depression Inventory. San Antonio, TX: Psychological Corporation.
6. Beck DM, Kastner S. 2005. Stimulus context modulates competition in human extrastriate cortex. Nat Neurosci 8:1110-1116. (Pubitemid 41061523)
7. Biederman J, Mick E, Faraone SV. 2000. Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission defi nition and symptom type. Am J Psychiatry 157:816-818. (Pubitemid 30249663)
8. Biederman J, Makris N, Valera EM, Monuteaux MC, Goldstein JM, Buka S, et al. 2008. Towards further understanding of the co-morbidity between attention deficit hyperactivity disorder and bipolar disorder: a MRI study of brain volumes. Psychol Med 38:1045-1056. (Pubitemid 351769218)
9. Bookstein FL. 2001. "Voxel-based morphometry" should not be used with imperfectly registered images. Neuroimage 14: 1454-1462. (Pubitemid 33124193)
10. Booth JR, Burman DD, Meyer JR, Lei Z, Trommer BL, Davenport ND, et al. 2005. Larger deficits in brain networks for response inhibition than for visual selective attention in attention deficit hyperactivity disorder (ADHD). J Child Psychol Psychiatry 46:94-111. (Pubitemid 40220798)
11. Brieber S, Neufang S, Bruning N, Kamp-Becker I, Remschmidt H, Herpertz-Dahlmann B, et al. 2007. Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder. J Child Psychol Psychiatry 48:1251-1258. (Pubitemid 350256552)
12. Bullier J, Hupe JM, James AC, Girard P. 2001. The role of feedback connections in shaping the responses of visual cortical neurons. Prog Brain Res 134:193-204.
13. Carmona S, Vilarroya O, Bielsa A, Tremols V, Soliva JC, Rovira M, et al. 2005. Global and regional gray matter reductions in ADHD: a voxel-based morphometric study. Neurosci Lett 389:88-93. (Pubitemid 41242891)
14. Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS, et al. 2002. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. J Am Med Assoc 288: 1740-1748.
15. Corbetta M, Shulman GL. 2002. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 3:201-215. (Pubitemid 135706590)
16. Desimone R, Duncan J. 1995. Neural mechanisms of selective visual attention. Annu Rev Neurosci 18:193-222.
17. Douaud G, Gaura V, Ribeiro MJ, Lethimonnier F, Maroy R, Verny C, et al. 2006. Distribution of grey matter atrophy in Hunting-ton's disease patients: a combined ROI-based and voxel-based morphometric study. Neuroimage 32:1562-1575. (Pubitemid 44332291)
18. Durston S, Hulshoff Pol HE, Schnack HG, Buitelaar JK, Steen-huis MP, Minderaa RB, et al. 2004. Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings. J Am Acad Child Adolesc Psychiatry 43:332-340. (Pubitemid 41615013)
19. Ebert D, Krause J, Roth-Sackenheim C. 2003. ADHD in adulthood-guidelines based on expert consensus with DGPPN support. Nervenarzt 74:939-946.
20. Eickhoff SB, Stephan KE, Mohlberg H, Grefkes C, Fink GR, Amunts K, et al. 2005. A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data. Neuroimage 25:1325-1335. (Pubitemid 40591672)
21. Ellison-Wright I, Ellison-Wright Z, Bullmore E. 2008. Structural brain change in Attention deficit hyperactivity disorder identi-fi ed by meta-analysis. BMC Psychiatry 8:51.
22. Epstein JN, Conners CK, Erhardt D, March JS, Swanson JM. 1997. Asymmetrical hemispheric control of visual-spatial attention in adults with attention deficit hyperactivity disorder. Neuropsychology 11:467-473. (Pubitemid 27459753)
23. Fayyad J, De Graaf R, Kessler R, Alonso J, Angermeyer M, Demyttenaere K, et al. 2007. Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. Br J Psychiatry 190:402-409. (Pubitemid 46706952)
24. Filipek PA, Semrud-Clikeman M, Steingard RJ, Renshaw PF, Kennedy DN, Biederman J. 1997. Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls. Neurology 48:589-601. (Pubitemid 27120091)
25. First MB, Gibbon M, Spitzer RL, Williams JB, Smith BL. 1997. Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II). Washington, DC: American Psychiatric Press.
26. Frodl T, Stauber J, Schaaff N, Koutsouleris N, Scheuerecker J, Ewers M, et al. 2010. Amygdala reduction in patients with ADHD compared with major depression and healthy volunteers. Acta Psychiatr Scand 121:111-118.
27. Genovese CR, Lazar NA, Nichols T. 2002. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 15:870-878. (Pubitemid 34852500)
28. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. 2001. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 14: 21-36. (Pubitemid 32552740)
29. Good CD, Scahill RI, Fox NC, Ashburner J, Friston KJ, Chan D, et al. 2002. Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias. Neuroimage 17:29-46.
30. Hervey AS, Epstein JN, Curry JF. 2004. Neuropsychology of adults with attention-deficit/hyperactivity disorder: a meta-analytic review. Neuropsychology 18:485-503. (Pubitemid 38944385)
31. Hesslinger B, Tebartz van Elst L, Thiel T, Haegele K, Hennig J, Ebert D. 2002. Frontoorbital volume reductions in adult patients with attention deficit hyperactivity disorder. Neurosci Lett 328:319-321. (Pubitemid 34876674)
32. Hochstein S, Ahissar M. 2002. View from the top: hierarchies and reverse hierarchies in the visual system. Neuron 36:791-804. (Pubitemid 35447852)
33. Hopf JM, Noesselt T, Tempelmann C, Braun J, Schoenfeld MA, Heinze HJ. 2004. Popout modulates focal attention in the primary visual cortex. Neuroimage 22:574-582. (Pubitemid 38759419)
34. Kamitani Y, Tong F. 2005. Decoding the visual and subjective contents of the human brain. Nat Neurosci 8:679-685. (Pubitemid 40594211)
35. Kastner S, Ungerleider LG. 2000. Mechanisms of visual attention in the human cortex. Annu Rev Neurosci 23:315-341. (Pubitemid 30350046)
36. Keller SS, Wilke M, Wieshmann UC, Sluming VA, Roberts N. 2004. Comparison of standard and optimized voxel-based mor-phometry for analysis of brain changes associated with temporal lobe epilepsy. Neuroimage 23:860-868. (Pubitemid 39446520)
37. Konrad K, Neufang S, Hanisch C, Fink GR, Herpertz-Dahlmann B. 2006. Dysfunctional attentional networks in children with attention deficit/hyperactivity disorder: evidence from an event-related functional magnetic resonance imaging study. Biol Psychiatry 59:643-651. (Pubitemid 43357959)
38. Krause KH, Krause J, Trott GE. 1998. Hyperkinetic syndrome (attention deficit hyperactivity disorder) in adulthood. Nerve-narzt 69:543-556. (Pubitemid 28366211)
39. Makris N, Biederman J, Valera EM, Bush G, Kaiser J, Kennedy DN, et al. 2007. Cortical thinning of the attention and executive function networks in adults with attention-deficit/hyperactivity disorder. Cereb Cortex 17:1364-1375. (Pubitemid 47343622)
40. Makris N, Seidman LJ, Valera EM, Biederman J, Monuteaux MC, Kennedy DN, et al. 2010. Anterior cingulate volumetric alterations in treatment-naive adults with ADHD: a pilot study. J Atten Disord 13:407-413.
41. Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. 2003. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19: 1233-1239. (Pubitemid 36918259)
42. Martinez A, Anllo-Vento L, Sereno MI, Frank LR, Buxton RB, Dubowitz DJ, et al. 1999. Involvement of striate and extrastriate visual cortical areas in spatial attention. Nat Neurosci 2: 364-369. (Pubitemid 30491280)
43. McAlonan GM, Cheung V, Cheung C, Chua SE, Murphy DG, Suckling J, et al. 2007. Mapping brain structure in attention deficit-hyperactivity disorder: a voxel-based MRI study of regional grey and white matter volume. Psychiatry Res 154: 171-180. (Pubitemid 46275443)
44. Mega MS, Cummings JL. 1994. Frontal-subcortical circuits and neuropsychiatric disorders. J Neuropsychiatry Clin Neurosci 6:358-370. (Pubitemid 24344856)
45. Mostofsky SH, Cooper KL, Kates WR, Denckla MB, Kaufmann WE. 2002. Smaller prefrontal and premotor volumes in boys with attention-deficit/hyperactivity disorder. Biol Psychiatry 52:785-794.
46. Overmeyer S, Bullmore ET, Suckling J, Simmons A, Williams SC, Santosh PJ, et al. 2001. Distributed grey and white matter deficits in hyperkinetic disorder: MRI evidence for anatomical abnormality in an attentional network. Psychol Med 31:1425-1435. (Pubitemid 33040366)
47. Paradiso MA. 2002. Perceptual and neuronal correspondence in primary visual cortex. Curr Opin Neurobiol 12:155-161.
48. Pascual-Leone A, Walsh V. 2001. Fast backprojections from the motion to the primary visual area necessary for visual awareness. Science 292:510-512. (Pubitemid 32335955)
49. Perchet C, Revol O, Fourneret P, Mauguiere F, Garcia-Larrea L. 2001. Attention shifts and anticipatory mechanisms in hyperactive children: an ERP study using the Posner paradigm. Biol Psychiatry 50:44-57. (Pubitemid 32701993)
50. Perlov E, Philipsen A, Tebartz van Elst L, Ebert D, Henning J, Maier S, et al. 2008. Hippocampus and amygdala morphology in adults with attention-deficit hyperactivity disorder. J Psychiatry Neurosci 33:509-515.
51. Pessoa L, Kastner S, Ungerleider LG. 2003. Neuroimaging studies of attention: from modulation of sensory processing to top-down control. J Neurosci 23:3990-3998. (Pubitemid 36958415)
52. Posner MI, Gilbert CD. 1999. Attention and primary visual cortex. Proc Natl Acad Sci USA 96:2585-2587. (Pubitemid 29148759)
53. Posner MI, Petersen SE. 1990. The attention system of the human brain. Annu Rev Neurosci 13:25-42. (Pubitemid 20100639)
54. Reetz K, Lencer R, Steinlechner S, Gaser C, Hagenah J, Buchel C, et al. 2008. Limbic and frontal cortical degeneration is associated with psychiatric symptoms in PINK1 mutation carriers. Biol Psychiatry 64:241-247.
55. Ress D, Backus BT, Heeger DJ. 2000. Activity in primary visual cortex predicts performance in a visual detection task. Nat Neurosci 3:940-945.
56. Rösler M, Retz W, Retz-Junginger P, Thome J, Supprian T, Nissen T, et al. 2004. Tools for the diagnosis of attention-deficit/ hyperactivity disorder in adults. Self-rating behaviour questionnaire and diagnostic checklist. Nervenarzt 75:888-895. (Pubitemid 39312514)
57. Rubia K, Smith AB, Brammer MJ, Taylor E. 2007. Temporal lobe dysfunction in medication-naive boys with attention-deficit/ hyperactivity disorder during attention allocation and its relation to response variability. Biol Psychiatry 62:999-1006. (Pubitemid 47562367)
58. R ü sch N, Tebartz van Elst L, Ludaescher P, Wilke M, Huppertz HJ, Thiel T, et al. 2003 A voxel-based morphometric MRI study in female patients with borderline personality disorder. Neuroimage 20: 385-392.
59. Salmond CH, Ashburner J, Vargha-Khadem F, Connelly A, Gadian DG, Friston KJ. 2002. The precision of anatomical normalization in the medial temporal lobe using spatial basis functions. Neuroimage 17:507-512.
60. Schöchlin C, Engel RR. 2005. Neuropsychological performance in adult attention-deficit hyperactivity disorder: Meta-analysis of empirical data. Arch Clin Neuropsychol 20: 727-744. (Pubitemid 40984658)
61. Seidman LJ. 2006. Neuropsychological functioning in people with ADHD across the lifespan. Clin Psychol Rev 26:466-485.
62. Seidman LJ, Valera EM, Makris N. 2005. Structural brain imaging of attention-deficit/hyperactivity disorder. Biol Psychiatry 57:1263-1272. (Pubitemid 40798545)
63. Seidman LJ, Valera EM, Makris N, Monuteaux MC, Boriel DL, Kelkar K, et al. 2006. Dorsolateral prefrontal and anterior cin-gulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identifi ed by magnetic resonance imaging. Biol Psychiatry 60:1071-1080. (Pubitemid 44754859)
64. Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A, et al. 2006. Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 63: 540-549.
65. Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Green-stein D, et al. 2007. Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci USA 104:19649-19654.
66. Shaw P, Lalonde F, Lepage C, Rabin C, Eckstrand K, Sharp W, et al. 2009a. Development of cortical asymmetry in typically developing children and its disruption in attention-deficit/ hyperactivity disorder. Arch Gen Psychiatry 66:888-896.
67. Shaw P, Sharp WS, Morrison M, Eckstrand K, Greenstein DK, Clasen LS, et al. 2009b. Psychostimulant treatment and the developing cortex in attention deficit hyperactivity disorder. Am J Psychiatry 166:58-63.
68. Shen S, Szameitat AJ, Sterr A. 2007. VBM lesion detection depends on the normalization template: a study using simulated atrophy. Magn Reson Imaging 25:1385-1396. (Pubitemid 350122911)
69. Shuter B, Yeh IB, Graham S, Au C, Wang SC. 2008. Reproducibil-ity of brain tissue volumes in longitudinal studies: effects of changes in signal-to-noise ratio and scanner software. Neuroimage 41:371-379.
70. Silver MA, Ress D, Heeger DJ. 2007. Neural correlates of sustained spatial attention in human early visual cortex. J Neuro-physiol 97:229-237. (Pubitemid 46143353)
71. Smith AB, Taylor E, Brammer M, Toone B, Rubia K. 2006. Task-specific hypoactivation in prefrontal and temporoparietal brain regions during motor inhibition and task switching in medication-naive children and adolescents with attention deficit hyperactivity disorder. Am J Psychiatry 163:1044-1051. (Pubitemid 44464491)
72. Somers DC, Dale AM, Seiffert AE, Tootell RB. 1999. Functional MRI reveals spatially specific attentional modulation in human primary visual cortex. Proc Natl Acad Sci USA 96: 1663-1668. (Pubitemid 29098508)
73. Sowell ER, Thompson PM, Welcome SE, Henkenius AL, Toga AW, Peterson BS. 2003. Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet 362:1699-1707. (Pubitemid 37468319)
74. Stein MA, Sandoval R, Szumowski E, Roizen N, Reinecke MA, Blondis TA, et al. 1995. Psychometric characteristics of the Wender Utah Rating Scale (WURS): reliability and factor structure for men and women. Psychopharmacol Bull 31: 425-433.
75. Tamm L, Menon V, Reiss AL. 2006. Parietal attentional system aberrations during target detection in adolescents with attention deficit hyperactivity disorder: event-related fMRI evidence. Am J Psychiatry 163:1033-1043. (Pubitemid 44464490)
76. Treue S. 2001. Neural correlates of attention in primate visual cortex. Trends Neurosci 24:295-300. (Pubitemid 32304473)
77. Tucha O, Walitza S, Mecklinger L, Sontag TA, Kubber S, Linder M, et al. 2006. Attentional functioning in children with ADHD-predominantly hyperactive-impulsive type and children with ADHD-combined type. J Neural Transm 113:1943-1953. (Pubitemid 44749637)
78. Valera EM, Faraone SV, Murray KE, Seidman LJ. 2007. Meta-analysis of structural imaging fi ndings in attention-deficit/ hyperactivity disorder. Biol Psychiatry 61:1361-1369. (Pubitemid 46855763)
79. van der Stelt O, van der Molen M, Boudewijn Gunning W, Kok A. 2001. Neuroelectrical signs of selective attention to color in boys with attention-deficit hyperactivity disorder. Brain Res Cogn Brain Res 12:245-264.
80. Vance A, Silk TJ, Casey M, Rinehart NJ, Bradshaw JL, Bellgrove MA, et al. 2007. Right parietal dysfunction in children with attention deficit hyperactivity disorder, combined type: a functional MRI study. Mol Psychiatry 12:826-832, 793. (Pubitemid 47347794)
81. Ward MF, Wender PH, Reimherr FW. 1993. The Wender Utah Rating Scale: an aid in the retrospective diagnosis of childhood attention deficit hyperactivity disorder. Am J Psychiatry 150: 885-890. (Pubitemid 23156767)
82. Wilke M, Schmithorst VJ, Holland SK. 2002. Assessment of spatial normalization of whole-brain magnetic resonance images in children. Hum Brain Mapp 17:48-60. (Pubitemid 34966796)
83. Wilke M, Holland SK, Altaye M, Gaser C. 2008. Template-O-Matic: a toolbox for creating customized pediatric templates. Neuroimage 41:903-913.
84. Willcutt EG, Doyle AE, Nigg JT, Faraone SV, Pennington BF. 2005. Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biol Psychiatry 57:1336-1346. (Pubitemid 40798553)
85. Wolosin SM, Richardson ME, Hennessey JG, Denckla MB, Mostofsky SH. 2009. Abnormal cerebral cortex structure in children with ADHD. Hum Brain Mapp 30:175-184.
86. Wood C, Maruff P, Levy F, Farrow M, Hay D. 1999. Covert orienting of visual spatial attention in attention deficit hyper-activity disorder: does comorbidity make a difference? Arch Clin Neuropsychol 14:179-189. (Pubitemid 29108543)
87. Yang P, Wang PN, Chuang KH, Jong YJ, Chao TC, Wu MT. 2008. Absence of gender effect on children with attention-deficit/hyperactivity disorder as assessed by optimized voxel-based morphometry. Psychiatry Res Neuroimaging 164: 245-253.