Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder

Journal of Child Psychology and Psychiatry and Allied Disciplines

Volumn 48, Issue 12, 2007, Pages 1251-1258

  Brieber, Sarah ^a,b   Neufang, Susanne ^a,b   Bruning, Nicole ^b   Kamp Becker, Inge ^d   Remschmidt, Helmut ^d   Herpertz Dahlmann, Beate ^b   Fink, Gereon R ^a,c   Konrad, Kerstin ^a,b  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

ADD ADHD; Autistic disorder; Structural MRI; VBM

Indexed keywords

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; BRAIN DEVELOPMENT; BRAIN SIZE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; GRAY MATTER; HUMAN; MALE; MORPHOMETRICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; SYMPTOM; TEMPORAL LOBE;

ADOLESCENT; ASPERGER SYNDROME; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; AUTISTIC DISORDER; BRAIN; BRAIN MAPPING; CHILD; FRONTAL LOBE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INTERPERSONAL RELATIONS; MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; SEVERITY OF ILLNESS INDEX; TEMPORAL LOBE;

EID: 37149027211     PISSN: 00219630     EISSN: 14697610     Source Type: Journal    
DOI: 10.1111/j.1469-7610.2007.01799.x     Document Type: Article

References (56)

1. Abell, F., Krams, M., Ashburner, J., Passingham, R., Friston, K., Frackowiak, R., Happé, F., Frith, C. Frith, U. (1999). The neuroanatomy of autism: A voxel-based whole brain analysis of structural scans. Neuroreport, 10, 1647 1651.
2. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th edn). Washington, DC : APA.
3. Ashburner, J. Friston, K.J. (2000). Voxel-based morphometry - the methods. Neuroimage, 11, 805 821.
4. Belmonte, M.K. Yurgelun-Todd, D.A. (2003). Functional anatomy of impaired selective attention and compensatory processing in autism. Brain Research Cognitive Brain Research, 17, 651 664.
5. Boelte, S., Crecelius, K. Poustka, F. (2000). Der Fragebogen ueber Verhalten und soziale Kommunikation: psychometrische Eigenschaften eines Autismus-Screening-Instruments fuer Forschung und Praxis. Diagnostica, 46, 149 155.
6. Booth, J.R., Burman, D.D., Meyer, J.R., Trommer, B.L., Davenport, N.D., Parrish, T.B., Gitelman, D.R. Mesulam, M.M. (2004). Brain-behavior correlation in children depends on the neurocognitive network. Human Brain Mapping, 23, 99 108.
7. Brambilla, P., Hardan, A., di Nemi, S.U., Perez, J., Soares, J.C. Barale, F. (2003). Brain anatomy and development in autism: Review of structural MRI studies. Brain Research Bulletin, 61, 557 569.
8. Bueller, J.A., Aftab, M., Sen, S., Gomez-Hassan, D., Burmeister, M. Zubieta, J.K. (2006). BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects. Biological Psychiatry, 59, 812 815.
9. Buitelaar, J.K., der Wees, M., Swaab-Barneveld, H. der Gaag, R.J. (1999). Theory of mind and emotion-recognition functioning in autistic spectrum disorders and in psychiatric control and normal children. Development and Psychopathology, 11, 39 58.
10. Castellanos, F.X., Lee, P.P., Sharp, W., Jeffries, N.O., Greenstein, D.K., Clasen, L.S., Blumenthal, J.D., James, R.S., Ebens, C.L., Walter, J.M., Zijdenbos, A., Evans, A.C., Giedd, J.N. Rapoport, J.L. (2002). Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. Journal of the American Medical Association, 288, 1740 1748.
11. Castelli, F., Frith, C., Happé, F. Frith, U. (2002). Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain, 125, 1839 1849.
12. Clark, T., Feehan, C., Tinline, C. Vostanis, P. (1999). Autistic symptoms in children with attention deficit-hyperactivity disorder. European Child and Adolescent Psychiatry, 8, 50 55.
13. Connolly, A.M., Chez, M., Streif, E.M., Keeling, R.M., Golumbek, P.T., Kwon, J.M., Riviello, J.J., Robinson, R.G., Neuman, R.J. Deuel, R.M. (2006). Brain-derived neurotrophic factor and autoantibodies to neural antigens in sera of children with autistic spectrum disorders, Landau-Kleffner syndrome, and epilepsy. Biological Psychiatry, 59, 354 363.
14. Corbetta, M. Shulman, G.L. (2002). Control of goal-directed and stimulus-driven attention in the brain. Nature Reviews Neuroscience, 3, 201 215.
15. Delmo, C., Weiffenbach, O., Gabriel, M., Stadler, C. Poustka, F. (2001). Diagnostisches Interview Kiddie-Sads-Present and Lifetime Version (K-SADS-PL). 5. Auflage der deutschen Forschungsversion, erweitert um ICD-10-Diagnostik.[5th edition of the German research version with the addition of ICD-10-diagnosis ]. Frankfurt : Klinik für Psychiatrie und Psychotherapie des Kindes-und Jugendalters, 1 241.
16. Döpfner, M. Lehmkuhl, G. (1998). Diagnostik - System für psychische Störungen im Kindes- und Jugendalter nach ICD-10 und DSM-IV. Bern : Huber.
17. Durston, S. (2003). A review of the biological bases of ADHD: What have we learned from imaging studies Mental Retardation and Developmental Disabilities Research Reviews, 9, 184 195.
18. Egan, M.F., Kojima, M., Callicott, J.H., Goldberg, T.E., Kolachana, B.S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D. Dean, M. (2003). The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell, 112, 257 269.
19. Fayed, N. Modrego, P.J. (2005). Comparative study of cerebral white matter in autism and attention-deficit/hyperactivity disorder by means of magnetic resonance spectroscopy. Academic Radiology, 12, 566 569.
20. Fombonne, E. (2003). Epidemiological surveys of autism and other pervasive developmental disorders: An update. Journal of Autism and Developmental Disorders, 33, 365 382.
21. Frazier, J.A., Chiu, S., Breeze, J.L., Makris, N., Lange, N., Kennedy, D.N., Herbert, M.R., Bent, E.K., Koneru, V.K., Dieterich, M.E., Hodge, S.M., Rauch, S.L., Grant, P.E., Cohen, B.M., Seidman, L.J., Caviness, V.S. Biederman, J. (2005). Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder. American Journal of Psychiatry, 162, 1256 1265.
22. Friedel, S., Horro, F.F., Wermter, A.K., Geller, F., Dempfle, A., Reichwald, K., Smidt, J., Bronner, G., Konrad, K., Herpertz-Dahlmann, B., Warnke, A., Hemminger, U., Linder, M., Kiefl, H., Goldschmidt, H.P., Siegfried, W., Remschmidt, H., Hinney, A. Hebebrand, J. (2005). Mutation screen of the brain derived neurotrophic factor gene (BDNF): Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder. American Journal of Medical Genetics, Part B:Neuropsychiatric Genetics, 132, 96 99.
23. Geurts, H.M., Verte, S., Oosterlaan, J., Roeyers, H., Hartman, C.A., Mulder, E.J., Berckelaer-Onnes, I.A. Sergeant, J.A. (2004a). Can the Children's Communication Checklist differentiate between children with autism, children with ADHD, and normal controls Journal of Child Psychology and Psychiatry, 45, 1437 1453.
24. Geurts, H.M., Verte, S., Oosterlaan, J., Roeyers, H. Sergeant, J.A. (2004b). How specific are executive functioning deficits in attention deficit hyperactivity disorder and autism Journal of Child Psychology and Psychiatry, 45, 836 854.
25. Goldberg, M.C., Mostofsky, S.H., Cutting, L.E., Mahone, E.M., Astor, B.C., Denckla, M.B. Landa, R.J. (2005). Subtle executive impairment in children with autism and children with ADHD. Journal of Autism and Developmental Disorders 35, 279 293.
26. Goldstein, S. Schwebach, A.J. (2004). The comorbidity of pervasive developmental disorder and attention deficit hyperactivity disorder: Results of a retrospective chart review. Journal of Autism and Developmental Disorders, 34, 329 339.
27. Good, C.D., Johnsrude, I., Ashburner, J., Henson, R.N., Friston, K.J. Frackowiak, R.S. (2001). Cerebral asymmetry and the effects of sex and handedness on brain structure: A voxel-based morphometric analysis of 465 normal adult human brains. Neuroimage, 14, 685 700.
28. Handen, B.L., Johnson, C.R. Lubetsky, M. (2000). Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. Journal of Autism and Developmental Disorders, 30, 245 255.
29. Happé, F., Booth, R., Charlton, R. Hughes, C. (2006). Executive function deficits in autism spectrum disorders and attention-deficit/ hyperactivity disorder: Examining profiles across domains and ages. Brain and Cognition, 61, 25 39.
30. Hattori, J., Ogino, T., Abiru, K., Nakano, K., Oka, M. Ohtsuka, Y. (2006). Are pervasive developmental disorders and attention-deficit/ hyperactivity disorder distinct disorders Brain and Development, 28, 371 374.
31. Howlin, P. (2003). Outcome of high-functioning adults with and without early language delays: Implications for the differentiation between autism and Asperger syndrome. Journal of Autism and Developmental Disorders, 33, 3 13.
32. Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., Williamson, D. Ryan, N. (1997). Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 980 988.
33. Konrad, K., Neufang, S., Hanisch, C., Fink, G.R. Herpertz-Dahlmann, B. (2006). Dysfunctional attentional networks in children with attention deficit/hyperactivity disorder: Evidence from an event-related functional magnetic resonance imaging study. Biological Psychiatry, 59, 643 651.
34. LeCouteur, A., Rutter, M., Lord, C., Rios, P., Robertson, S., Holdgrafer, M. McLennan, J. (1989). Autism diagnostic interview: A standardized investigator-based instrument. Journal of Autism and Developmental Disorders, 19, 363 387.
35. Lord, C., Risi, S., Lambrecht, L., Cook, E.H., Leventhal, B.L., DiLavore, P.C., Pickles, A. Rutter, M. (2000). The Autism Diagnostic Observation Schedule: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205 223.
36. Manjaly, Z.M., Bruning, N., Neufang, S., Stephan, K.E., Brieber, S., Marshall, J.C., Kamp-Becker, I., Remschmidt, H., Herpertz-Dahlmann, B., Konrad, K. Fink, G.R. (2007). Neurophysiological correlates of relatively enhanced local visual search in autistic adolescents. Neuroimage, 35, 283 291.
37. Mostofsky, S.H., Cooper, K.L., Kates, W.R., Denckla, M.B. Kaufmann, W.E. (2002). Smaller prefrontal and premotor volumes in boys with attention-deficit/hyperactivity disorder. Biological Psychiatry, 52, 785 794.
38. Nichols, T., Brett, M., Andersson, J., Wager, T. Poline, J.B. (2005). Valid conjunction inference with the minimum statistic. Neuroimage, 25, 653 660.
39. Ozonoff, S. Jensen, J. (1999). Brief report: Specific executive function profiles in three neurodevelopmental disorders. Journal of Autism and Developmental Disorders, 29, 171 177.
40. Rubia, K., Overmeyer, S., Taylor, E., Brammer, M., Williams, S.C., Simmons, A. Bullmore, E.T. (1999). Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control:A study with functional MRI. American Journal of Psychiatry, 156, 891 896.
41. Salmond, C.H., Ashburner, J., Connelly, A., Friston, K.J., Gadian, D.G. Vargha-Khadem, F. (2005). The role of the medial temporal lobe in autistic spectrum disorders. European Journal of Neuroscience, 22, 764 772.
42. Saxe, R. Kanwisher, N. (2003). People thinking about thinking people. The role of the temporo-parietal junction in 'theory of mind'. Neuroimage, 19, 1835 1842.
43. Schatz, A.M., Weimer, A.K. Trauner, D.A. (2002). Brief report: Attention differences in Asperger syndrome. Journal of Autism and Developmental Disorders, 32, 333 336.
44. Schmitz, N., Rubia, K., Daly, E., Smith, A., Williams, S. Murphy, D.G. (2006). Neural correlates of executive function in autistic spectrum disorders. Biological Psychiatry, 59, 7 16.
45. Seidman, L.J., Valera, E.M. Makris, N. (2005). Structural brain imaging of attention-deficit/hyperactivity disorder. Biological Psychiatry, 57, 1263 1272.
46. Sergeant, J.A., Geurts, H. Oosterlaan, J. (2002). How specific is a deficit of executive functioning for attention-deficit/hyperactivity disorder Behavioural Brain Research, 130, 3 28.
47. Sim, K., DeWitt, I., Ditman, T., Zalesak, M., Greenhouse, I., Goff, D., Weiss, A.P. Heckers, S. (2006). Hippocampal and parahippocampal volumes in schizophrenia: A structural MRI study. Schizophrenia Bulletin, 32, 332 340.
48. Smalley, S.L., Kustanovich, V., Minassian, S.L., Stone, J.L., Ogdie, M.N., McGough, J.J., McCracken, J.T., MacPhie, I.L., Francks, C., Fisher, S.E., Cantor, R.M., Monaco, A.P. Nelson, S.F. (2002). Genetic linkage of attention-deficit/hyperactivity disorder on chromosome 16p13, in a region implicated in autism. American Journal of Human Genetics, 71, 959 963.
49. Sowell, E.R., Thompson, P.M., Welcome, S.E., Henkenius, A.L., Toga, A.W. Peterson, B.S. (2003). Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet, 362, 1699 1707.
50. Sturm, H., Fernell, E. Gillberg, C. (2004). Autism spectrum disorders in children with normal intellectual levels: Associated impairments and subgroups. Developmental Medicine and Child Neurology, 46, 444 447.
51. Suzuki, M., Hagino, H., Nohara, S., Zhou, S.Y., Kawasaki, Y., Takahashi, T., Matsui, M., Seto, H., Ono, T. Kurachi, M. (2005). Male-specific volume expansion of the human hippocampus during adolescence. Cerebral Cortex, 15, 187 193.
52. Vogeley, K., Bussfeld, P., Newen, A., Herrmann, S., Happé, F., Falkai, P., Maier, W., Shah, N.J., Fink, G.R. Zilles, K. (2001). Mind reading: Neural mechanisms of theory of mind and self-perspective. Neuroimage, 14, 170 181.
53. Waiter, G.D., Williams, J.H., Murray, A.D., Gilchrist, A., Perrett, D.I. Whiten, A. (2004). A voxel-based investigation of brain structure in male adolescents with autistic spectrum disorder. Neuroimage, 22, 619 625.
54. Weiß, R.H. (1998). Grundintelligenztest Skala 2(CFT 20) mit Wortschatztest (WS) und Zahlenfolgentest (ZF)(4th edn). Braunschweig : Westermann.
55. Westerberg, H., Hirvikoski, T., Forssberg, H. Klingberg, T. (2004). Visuo-spatial working memory span:A sensitive measure of cognitive deficits in children with ADHD. Child Neuropsychology, 10, 155 161.
56. World Health Organization. (1993). The ICD-10 classification of mental and behavioural disorders: Diagnostic criteria for research. Geneva : WHO.