Defective CFTR-dependent CREB activation results in impaired Spermatogenesis and Azoospermia

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Xu, Wen Ming ^a,b   Chen, Jing ^b   Chen, Hui ^b   Diao, Rui Ying ^b,c   Fok, Kin Lam ^b   Dong, Jian Da ^b   Sun, Ting Ting ^b   Chen, Wen Ying ^b,d   Yu, Mei Kuen ^b   Zhang, Xiao Hu ^b   Tsang, Lai Ling ^b   Lau, Ann ^b   Shi, Qi Xian ^d   Shi, Qing Hua ^e   Huang, Ping Bo ^f   Chan, Hsiao Chang ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^c PEKING UNIVERSITY SHENZHEN HOSPITAL   (China)

^d INSTITUTE OF MATERIA MEDICA   (China)

^e UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^f HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BICARBONATE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; AZOOSPERMIA; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE ACTIVATION; GENE MUTATION; GENE REPRESSION; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PROTEIN DEFECT; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; RAT; SERTOLI CELL; SIGNAL TRANSDUCTION; SPERMATOGENESIS; SPERMATOZOON COUNT; TESTIS WEIGHT; ADULT; ANIMAL; DISEASE MODEL; ENZYME IMMUNOASSAY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MIDDLE AGED; MOUSE MUTANT; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

MUS; RATTUS;

ADENYLATE CYCLASE; ADULT; ANIMALS; AZOOSPERMIA; BICARBONATES; BLOTTING, WESTERN; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SERTOLI CELLS; SPERMATOGENESIS; YOUNG ADULT;

EID: 79955837870     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019120     Document Type: Article

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