Advances of study on translesion DNA synthesis polymerase kappa in mammalian cells

Progress in Biochemistry and Biophysics

Volumn 38, Issue 3, 2011, Pages 204-209

  Lü, Ling Na ^a   Tang, Tie Shan ^b   Guo, Cai Xia ^a  

^a Chinese Academy of Sciences   (China)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

Mutagenesis; Pol ; Translesion DNA synthesis

Indexed keywords

MAMMALIA;

EID: 79955830436     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2010.00353     Document Type: Article

References (40)

1. Guo C, Kosarek-Stancel J N, Tang T S, et al. Y-family DNA polymerases in mammalian cells. Cell Mol Life Sci, 2009, 66(14):2363-2381
2. Friedberg E C, Wagner R, Radman M. Specialized DNA polymerases, cellular survival, and the genesis of mutations. Science, 2002, 296(5573):1627-1630 (Pubitemid 34579143)
3. Friedberg E C. Suffering in silence: the tolerance of DNA damage. Nat Rev Mol Cell Biol, 2005, 6(12):943-953 (Pubitemid 41778713)
4. Waters L S, Minesinger B K, Wiltrout M E, et al. Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev, 2009, 73(1):134-154
5. Johnson R E, Washington M T, Prakash S, et al. Fidelity of human DNA polymerase eta. J Biol Chem, 2000, 275(11):7447-7450 (Pubitemid 30159635)
6. Johnson R E, Prakash S, Prakash L. Efficient bypass of a thyminethymine dimer by yeast DNA polymerase, Poleta. Science, 1999, 283(5404):1001-1004
7. Shachar S, Ziv O, Avkin S, et al. Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. Embo J, 2009, 28(4):383-393
8. Zhang Y, Yuan F, Wu X, et al. Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro. Nucleic Acids Res, 2000, 28(21):4138-4146
9. Gerlach V L, Aravind L, Gotway G, et al. Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily. Proc Natl Acad Sci USA, 1999, 96(21):11922-11927 (Pubitemid 29502834)
10. Jia L, Geacintov N E, Broyde S. The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine-or guanine-benzo [a]pyrenyl lesions. Nucleic Acids Res, 2008, 36(20):6571-6584
11. Lone S, Townson S A, Uljon S N, et al. Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell, 2007, 25(4):601-614
12. Ziv O, Geacintov N, Nakajima S, et al. DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients. Proc Natl Acad Sci USA, 2009, 106(28):11552-11557
13. Washington M T, Johnson R E, Prakash L, et al. Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. Proc Natl Acad Sci USA, 2002, 99(4):1910-1914 (Pubitemid 34168988)
14. Katafuchi A, Sassa A, Niimi N, et al. Critical amino acids in human DNA polymerases eta and kappa involved in erroneous incorporation of oxidized nucleotides. Nucleic Acids Res, 2010, 38(3):859-867
15. Haracska L, Unk I, Johnson R E, et al. Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA. Mol Cell Biol, 2002, 22(3):784-791 (Pubitemid 34053058)
16. Ogi T, Lehmann A R. The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair. Nat Cell Biol, 2006, 8(6):640-642 (Pubitemid 43827358)
17. Ogi T, Limsirichaikul S, Overmeer R M, et al. Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Mol Cell, 2010, 37(5):714-727
18. Guo C, Gao T, Confer N, et al. Multiple PolK (POLK) transcripts in mammalian testis. DNA Repair (Amst), 2005, 4(3):397-402 (Pubitemid 40127003)
19. Ogi T, Mimura J, Hikida M, et al. Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription. Genes Cells, 2001, 6(11):943-953 (Pubitemid 33100029)
20. Velasco-Miguel S, Richardson J A, Gerlach V L, et al. Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa. DNA Repair (Amst), 2003, 2(1):91-106 (Pubitemid 35435441)
21. Guo C, Tang T S, Bienko M, et al. Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance. J Biol Chem, 2008, 283(8):4658-4664
22. Lemée F, Bavoux C, Pillaire M J, et al. Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer. Oncogene, 2007, 26(23):3387-3394 (Pubitemid 46788878)
23. Bienko M, Green C M, Crosetto N, et al. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science, 2005, 310(5755):1821-1824 (Pubitemid 41814383)
24. Kai M, Wang T S. Checkpoint activation regulates mutagenic translesion synthesis. Genes Dev, 2003, 17(1):64-76 (Pubitemid 36062509)
25. Bi X, Barkley L R, Slater D M, et al. Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest. Mol Cell Biol, 2006, 26(9):3527-3540
26. Guo C, Fischhaber P L, Luk-Paszyc M J, et al. Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. Embo J, 2003, 22(24):6621-6630 (Pubitemid 38009608)
27. Ohashi E, Murakumo Y, Kanjo N, et al. Interaction of hREV1 with three human Y-family DNA polymerases. Genes Cells, 2004, 9(6):523-531 (Pubitemid 38877782)
28. Ohashi E, Hanafusa T, Kamei K, et al. Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function. Genes Cells, 2009, 14(2):101-111
29. Ogi T, Kannouche P, Lehmann A R. Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci. J Cell Sci, 2005, 118 (Pt 1):129-136 (Pubitemid 40277111)
30. Schenten D, Gerlach V L, Guo C, et al. DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Eur J Immunol, 2002, 32(11):3152-3160 (Pubitemid 35414873)
31. Ogi T, Shinkai Y, Tanaka K, et al. Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo [a]pyrene. Proc Natl Acad Sci USA, 2002, 99(24):15548-15553 (Pubitemid 35403971)
32. Faili A, Stary A, Delbos F, et al. A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta. J Immunol, 2009, 182(10):6353-6359
33. Stancel J N, McDaniel L D, Velasco S, et al. Polk mutant mice have a spontaneous mutator phenotype. DNA Repair (Amst), 2009, 8(12):1355-1362
34. Burr K L, Velasco-Miguel S, Duvvuri V S, et al. Elevated mutation rates in the germline of Polkappa mutant male mice. DNA Repair (Amst), 2006, 5(7):860-862 (Pubitemid 43928884)
35. Bi X, Slater D M, Ohmori H, et al. DNA polymerase kappa is specifically required for recovery from the benzo [a] pyrene-dihydrodiol epoxide (BPDE) - induced S-phase checkpoint. J Biol Chem, 2005, 280(23):22343-22355 (Pubitemid 40827891)
36. Takenaka K, Ogi T, Okada T, et al. Involvement of vertebrate Polkappa in translesion DNA synthesis across DNA monoalkylation damage. J Biol Chem, 2006, 281(4):2000-2004 (Pubitemid 43845787)
37. Ogi T, Ohashi E, Ohmori H. Mutagenesis by Escherichia coli DinB and its mammalian homolog Pol kappa. Tanpakushitsu Kakusan Koso, 2001, 46 (8 Suppl): 1155-1161
38. Bavoux C, Leopoldino A M, Bergoglio V, et al. Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Cancer Res, 2005, 65(1):325-330 (Pubitemid 40070825)
39. Bavoux C, Hoffmann J S, Cazaux C. Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase kappa. Biochimie, 2005, 87(7):637-646 (Pubitemid 40884626)
40. Wang H, Wu W, Wang H W, et al. Analysis of specialized DNA polymerases expression in human gliomas: association with prognostic significance. Neuro Oncol, 2010, 12(7):679-686