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Volumn 26, Issue 1, 2011, Pages 247-254

Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice

Author keywords

Cachexia; Fatigue; Leucine; Protein metabolism

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; GLYCINE; ISOLEUCINE; LEUCINE; LYSINE; MESSENGER RNA; SERINE; TAURINE; VALINE;

EID: 79955828066     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1269     Document Type: Article
Times cited : (47)

References (55)
  • 1
    • 27144513240 scopus 로고    scopus 로고
    • Cancer-associated malnutrition
    • Argiles JM: Cancer-associated malnutrition. Eur J Oncol Nurs 9: S39-S50, 2005.
    • (2005) Eur J Oncol Nurs , vol.9
    • Argiles, J.M.1
  • 2
  • 3
    • 33745624014 scopus 로고    scopus 로고
    • Definition of cancer cachexia: Effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis
    • Fearon KC, Voss AC and Hustead DS: Definition of cancer cachexia: effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis. Am J Clin Nutr 83: 1345-1350, 2006.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1345-1350
    • Fearon, K.C.1    Voss, A.C.2    Hustead, D.S.3
  • 7
    • 0033808169 scopus 로고    scopus 로고
    • Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway
    • Anthony JC, Yoshizawa F, Anthony TG, Vary TC, Jefferson LS and Kimball SR: Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway. J Nutr 130: 2413-2419, 2000.
    • (2000) J Nutr , vol.130 , pp. 2413-2419
    • Anthony, J.C.1    Yoshizawa, F.2    Anthony, T.G.3    Vary, T.C.4    Jefferson, L.S.5    Kimball, S.R.6
  • 8
    • 0035090371 scopus 로고    scopus 로고
    • Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine
    • Anthony JC, Anthony TG, Kimball SR and Jefferson LS: Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine. J Nutr 131: S856-S860, 2001.
    • (2001) J Nutr , vol.131
    • Anthony, J.C.1    Anthony, T.G.2    Kimball, S.R.3    Jefferson, L.S.4
  • 9
    • 35148822373 scopus 로고    scopus 로고
    • Effect of branched-chain amino acids on muscle atrophy in cancer cachexia
    • DOI 10.1042/BJ20070651
    • Eley HL, Russell ST and Tisdale MJ: Effect of branched-chain amino acids on muscle atrophy in cancer cachexia. Biochem J 407: 113-120, 2007. (Pubitemid 47535586)
    • (2007) Biochemical Journal , vol.407 , Issue.1 , pp. 113-120
    • Eley, H.L.1    Russell, S.T.2    Tisdale, M.J.3
  • 11
    • 0021129631 scopus 로고
    • Protein synthesis in muscle measured in vivo in cachectic patients with cancer
    • Emery PW, Edwards RH, Rennie MJ, Souhami RL and Halliday D: Protein synthesis in muscle measured in vivo in cachectic patients with cancer. Br Med J (Clin Res Ed) 289: 584-586, 1984. (Pubitemid 14009869)
    • (1984) British Medical Journal , vol.289 , Issue.6445 , pp. 584-586
    • Emery, P.W.1    Edwards, R.H.T.2    Rennie, M.J.3
  • 13
    • 11244299296 scopus 로고    scopus 로고
    • Proteasome activity is altered in skeletal muscle tissue of tumour-bearing rats fed a leucine-rich diet
    • DOI 10.1677/erc.1.00828
    • Ventrucci G, Mello MA and Gomes-Marcondes MC: Proteasome activity is altered in skeletal muscle tissue of tumour-bearing rats a leucine-rich diet. Endocr Relat Cancer 11: 887-895, 2004. (Pubitemid 40065560)
    • (2004) Endocrine-Related Cancer , vol.11 , Issue.4 , pp. 887-895
    • Ventrucci, G.1    Mello, M.A.R.2    Gomes-Marcondes, M.C.C.3
  • 15
    • 0036230645 scopus 로고    scopus 로고
    • Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation
    • Anthony JC, Reiter AK, Anthony TG, Crozier SJ, Lang CH, MacLean DA, Kimball SR and Jefferson LS: Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation Diabetes 51: 928-936, 2002.
    • (2002) Diabetes , vol.51 , pp. 928-936
    • Anthony, J.C.1    Reiter, A.K.2    Anthony, T.G.3    Crozier, S.J.4    Lang, C.H.5    MacLean, D.A.6    Kimball, S.R.7    Jefferson, L.S.8
  • 19
    • 0029100380 scopus 로고
    • Manifestations of cancer cachexia induced by colon 26 adenocarcinoma are not fully ascribable to interleukin-6
    • Soda K, Kawakami M, Kashii A and Miyata M: Manifestations of cancer cachexia induced by colon 26 adenocarcinoma are not fully ascribable to interleukin-6. Int J Cancer 62: 332-336, 1995.
    • (1995) Int J Cancer , vol.62 , pp. 332-336
    • Soda, K.1    Kawakami, M.2    Kashii, A.3    Miyata, M.4
  • 21
  • 22
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH and Fahey GC Jr: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123: 1939-1951, 1993.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey Jr., G.C.3
  • 23
    • 0027441733 scopus 로고
    • Rapid routine determination of amino acids in plasma by high-performance liquid chromatography with a 2-3 microns Spherisorb ODS II column
    • DOI 10.1016/0378-4347(93)80062-9
    • van Eijk HM, Rooyakkers DR and Deutz NE: Rapid routine determination of amino acids in plasma by high-performance liquid chromatography with a 2-3 microns Spherisorb ODS II column. J Chromatogr 620: 143-148, 1993. (Pubitemid 23317657)
    • (1993) Journal of Chromatography - Biomedical Applications , vol.620 , Issue.1 , pp. 143-148
    • Van Eijk, H.M.H.1    Rooyakkers, D.R.2    Deutz, N.E.P.3
  • 24
    • 0042195964 scopus 로고    scopus 로고
    • A fast and accurate method to measure both oxidative stress and vitality in a single organ slice
    • DOI 10.1016/S0003-2697(03)00292-6
    • van Hoorn EC, Sutmuller-Ooms M, De Vrij G, van Leeuwen PA and van Norren K: A fast and accurate method to measure both oxidative stress and vitality in a single organ slice. Anal Biochem 320: 82-87, 2003. (Pubitemid 36937070)
    • (2003) Analytical Biochemistry , vol.320 , Issue.1 , pp. 82-87
    • Van Hoorn, E.C.1    Sutmuller-Ooms, M.2    De Vrij, G.3    Van Leeuwen, P.A.M.4    Van Norren, K.5
  • 27
    • 40949155609 scopus 로고    scopus 로고
    • Myostatin and its precursor protein are increased in the skeletal muscle of patients with Type-II muscle fibre atrophy
    • Wojcik S, Nogalska A, Engel WK and Askanas V: Myostatin and its precursor protein are increased in the skeletal muscle of patients with Type-II muscle fibre atrophy. Folia Morphol (Warsz) 67: 6-12, 2008. (Pubitemid 351404053)
    • (2008) Folia Morphologica , vol.67 , Issue.1 , pp. 6-12
    • Wojcik, S.1    Nogalska, A.2    Engel, W.K.3    Askanas, V.4
  • 28
    • 0036752957 scopus 로고    scopus 로고
    • Plasma amino acid levels with a note on membrane transport: Characteristics, regulation, and metabolic significance
    • Cynober LA: Plasma amino acid levels with a note on membrane transport: characteristics, regulation, and metabolic significance. Nutrition 18: 761-766, 2002.
    • (2002) Nutrition , vol.18 , pp. 761-766
    • Cynober, L.A.1
  • 30
    • 0034972314 scopus 로고    scopus 로고
    • Quantitation of urinary 3-methylhistidine excretion in growing dogs as an index of in vivo skeletal muscle catabolism
    • DOI 10.1016/S0955-2863(01)00148-6, PII S0955286301001486
    • Hill AS, Marks SL and Rogers QR: Quantitation of urinary 3-methylhistidine excretion in growing dogs as an index of in vivo skeletal muscle catabolism. J Nutr Biochem 12: 346-350, 2001. (Pubitemid 32552050)
    • (2001) Journal of Nutritional Biochemistry , vol.12 , Issue.6 , pp. 346-350
    • Hill, A.S.1    Marks, S.L.2    Rogers, Q.R.3
  • 31
    • 0031908565 scopus 로고    scopus 로고
    • Urinary 3-methylhistidine excretion: Association with total body skeletal muscle mass by computerized axial tomography
    • Wang Z, Deurenberg P, Matthews DE and Heymsfield SB: Urinary 3-methylhistidine excretion: association with total body skeletal muscle mass by computerized axial tomography. JPEN J Parenter Enteral Nutr 22: 82-86, 1998. (Pubitemid 28117570)
    • (1998) Journal of Parenteral and Enteral Nutrition , vol.22 , Issue.2 , pp. 82-86
    • Wang, Z.1    Deurenberg, P.2    Matthews, D.E.3    Heymsfield, S.B.4
  • 33
    • 0020957875 scopus 로고
    • 3-Methylhistidine excretion and the urinary 3-methylhistidine/creatinine ratio are poor indicators of skeletal muscle protein breakdown
    • Rennie MJ and Millward DJ: 3-Methylhistidine excretion and the urinary 3-methylhistidine/creatinine ratio are poor indicators of skeletal muscle protein breakdown. Clin Sci (Lond) 65: 217-225, 1983. (Pubitemid 13076195)
    • (1983) Clinical Science , vol.65 , Issue.3 , pp. 217-225
    • Rennie, M.J.1    Millward, D.J.2
  • 34
    • 23944514295 scopus 로고    scopus 로고
    • Methods for measuring tissue protein breakdown rate in vivo
    • Chinkes DL: Methods for measuring tissue protein breakdown rate in vivo. Curr Opin Clin Nutr Metab Care 8: 534-537, 2005.
    • (2005) Curr Opin Clin Nutr Metab Care , vol.8 , pp. 534-537
    • Chinkes, D.L.1
  • 35
    • 0032755334 scopus 로고    scopus 로고
    • Amino acid concentration in the interstitium of human skeletal muscle: A microdialysis study
    • DOI 10.1046/j.1365-2362.1999.00551.x
    • Gutierrez A, Anderstam B and Alvestrand A: Amino acid concentration in the interstitium of human skeletal muscle: a microdialysis study. Eur J Clin Invest 29: 947-952, 1999. (Pubitemid 29532885)
    • (1999) European Journal of Clinical Investigation , vol.29 , Issue.11 , pp. 947-952
    • Gutierrez, A.1    Anderstam, B.2    Alvestrand, A.3
  • 36
    • 0032555944 scopus 로고    scopus 로고
    • The muscle regulatory factors MyoD and Myf-5 undergo distinct cell cycle-specific expression in muscle cells
    • DOI 10.1083/jcb.142.6.1447
    • Kitzmann M, Carnac G, Vandromme M, Primig M, Lamb NJ and Fernandez A: The muscle regulatory factors MyoD and myf-5 undergo distinct cell cycle-specific expression in muscle cells. J Cell Biol 142: 1447-1459, 1998. (Pubitemid 28452595)
    • (1998) Journal of Cell Biology , vol.142 , Issue.6 , pp. 1447-1459
    • Kitzmann, M.1    Carnac, G.2    Vandromme, M.3    Primig, M.4    Lamb, N.J.C.5    Fernandez, A.6
  • 38
    • 33746876019 scopus 로고    scopus 로고
    • Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia
    • DOI 10.1113/jphysiol.2006.110742
    • Rieu I, Balage M, Sornet C, Giraudet C, Pujos E, Grizard J, Mosoni L and Dardevet D: Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia. J Physiol 575: 305-315, 2006. (Pubitemid 44182713)
    • (2006) Journal of Physiology , vol.575 , Issue.1 , pp. 305-315
    • Rieu, I.1    Balage, M.2    Sornet, C.3    Giraudet, C.4    Pujos, E.5    Grizard, J.6    Mosoni, L.7    Dardevet, D.8
  • 42
    • 33847070862 scopus 로고    scopus 로고
    • Protein, glucose and lipid metabolism in the cancer cachexia: A preliminary report
    • Dodesini AR, Benedini S, Terruzzi I, Sereni LP and Luzi L: Protein, glucose and lipid metabolism in the cancer cachexia: A preliminary report. Acta Oncol 46: 118-120, 2007.
    • (2007) Acta Oncol , vol.46 , pp. 118-120
    • Dodesini, A.R.1    Benedini, S.2    Terruzzi, I.3    Sereni, L.P.4    Luzi, L.5
  • 43
    • 33751233252 scopus 로고    scopus 로고
    • Waste management-Cytokines, growth factors and cachexia
    • DOI 10.1016/j.cytogfr.2006.09.006, PII S1359610106000554
    • Saini A, Al-Shanti N and Stewart CE: Waste management - cytokines, growth factors and cachexia. Cytokine Growth Factor Rev 17: 475-486, 2006. (Pubitemid 44793120)
    • (2006) Cytokine and Growth Factor Reviews , vol.17 , Issue.6 , pp. 475-486
    • Saini, A.1    Nasser, A.-S.2    Stewart, C.E.H.3
  • 44
    • 0037329888 scopus 로고    scopus 로고
    • Aspects of organ protein, amino acid and glucose metabolism in a porcine model of hypermetabolic sepsis
    • DOI 10.1042/CS20020275
    • Bruins MJ, Deutz NE and Soeters PB: Aspects of organ protein, amino acid and glucose metabolism in a porcine model of hypermetabolic sepsis. Clin Sci (Lond) 104: 127-141, 2003. (Pubitemid 36238045)
    • (2003) Clinical Science , vol.104 , Issue.2 , pp. 127-141
    • Bruins, M.J.1    Deutz, N.E.P.2    Soeters, P.B.3
  • 47
    • 33646471651 scopus 로고    scopus 로고
    • Response of muscle protein and glutamine kinetics to branched-chain- enriched amino acids in intensive care patients after radical cancer surgery
    • Biolo G, De Cicco M, Dal Mas V, Lorenzon S, Antonione R, Ciocchi B, Barazzoni R, Zanetti M, Dore F and Guarnieri G: Response of muscle protein and glutamine kinetics to branched-chain-enriched amino acids in intensive care patients after radical cancer surgery. Nutrition 22: 475-482, 2006.
    • (2006) Nutrition , vol.22 , pp. 475-482
    • Biolo, G.1    De Cicco, M.2    Dal Mas, V.3    Lorenzon, S.4    Antonione, R.5    Ciocchi, B.6    Barazzoni, R.7    Zanetti, M.8    Dore, F.9    Guarnieri, G.10
  • 48
    • 0034851609 scopus 로고    scopus 로고
    • Oral supplementation of branched-chain amino acid improves nutritional status in elderly patients on chronic haemodialysis
    • Hiroshige K, Sonta T, Suda T, Kanegae K and Ohtani A: Oral supplementation of branched-chain amino acid improves nutritional status in elderly patients on chronic haemodialysis. Nephrol Dial Transplant 16: 1856-1862, 2001.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1856-1862
    • Hiroshige, K.1    Sonta, T.2    Suda, T.3    Kanegae, K.4    Ohtani, A.5
  • 49
    • 0038047688 scopus 로고    scopus 로고
    • Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: A double-blind, randomized trial
    • DOI 10.1016/S0016-5085(03)00323-8
    • Marchesini G, Bianchi G, Merli M, Amodio P, Panella C, Loguercio C, Rossi Fanelli F and Abbiati R: Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial. Gastroenterology 124: 1792-1801, 2003. (Pubitemid 36666776)
    • (2003) Gastroenterology , vol.124 , Issue.7 , pp. 1792-1801
    • Marchesini, G.1    Bianchi, G.2    Merli, M.3    Amodio, P.4    Panella, C.5    Loguercio, C.6    Fanelli, F.R.7    Abbiati, R.8
  • 50
    • 33748308712 scopus 로고    scopus 로고
    • Role of leucine in regulating food intake
    • author reply 1236-1238, 2006
    • Laviano A, Meguid MM, Inui A and Rossi-Fanelli F: Role of leucine in regulating food intake. Science 313: 1236-1238; author reply 1236-1238, 2006.
    • Science , vol.313 , pp. 1236-1238
    • Laviano, A.1    Meguid, M.M.2    Inui, A.3    Rossi-Fanelli, F.4
  • 51
    • 0035729373 scopus 로고    scopus 로고
    • Effect of a fish oil-enriched nutritional supplement on metabolic mediators in patients with pancreatic cancer cachexia
    • Barber MD, Fearon KC, Tisdale MJ, McMillan DC and Ross JA: Effect of a fish oil-enriched nutritional supplement on metabolic mediators in patients with pancreatic cancer cachexia. Nutr Cancer 40: 118-124, 2001. (Pubitemid 34274917)
    • (2001) Nutrition and Cancer , vol.40 , Issue.2 , pp. 118-124
    • Barber, M.D.1    Fearon, K.C.H.2    Tisdale, M.J.3    McMillan, D.C.4    Ross, J.A.5
  • 52
    • 0032859278 scopus 로고    scopus 로고
    • The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer
    • Barber MD, Ross JA, Voss AC, Tisdale MJ and Fearon KC: The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer. Br J Cancer 81: 80-86, 1999.
    • (1999) Br J Cancer , vol.81 , pp. 80-86
    • Barber, M.D.1    Ross, J.A.2    Voss, A.C.3    Tisdale, M.J.4    Fearon, K.C.5
  • 53
    • 2942706075 scopus 로고    scopus 로고
    • An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: A North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort
    • DOI 10.1200/JCO.2004.06.024
    • Jatoi A, Rowland K, Loprinzi CL, Sloan JA, Dakhil SR, MacDonald N, Gagnon B, Novotny PJ, Mailliard JA, Bushey TI, Nair S and Christensen B: An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort. J Clin Oncol 22: 2469-2476, 2004. (Pubitemid 41115406)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.12 , pp. 2469-2476
    • Jatoi, A.1    Rowland, K.2    Loprinzi, C.L.3    Sloan, J.A.4    Dakhil, S.R.5    MacDonald, N.6    Gagnon, B.7    Novotny, P.J.8    Mailliard, J.A.9    Bushey, T.I.L.10    Nair, S.11    Christensen, B.12
  • 55
    • 0033918233 scopus 로고    scopus 로고
    • Effect of oral Eicosapentaenoic acid on weight loss in patients with pancreatic cancer
    • Wigmore SJ, Barber MD, Ross JA, Tisdale MJ and Fearon KC: Effect of oral eicosapentaenoic acid on weight loss in patients with pancreatic cancer. Nutr Cancer 36: 177-184, 2000. (Pubitemid 30437038)
    • (2000) Nutrition and Cancer , vol.36 , Issue.2 , pp. 177-184
    • Wigmore, S.J.1    Barber, M.D.2    Ross, J.A.3    Tisdale, M.J.4    Fearon, K.C.H.5


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