Effects of administration of oral branched-chain amino acids on anorexia and caloric intake in cancer patients

Journal of the National Cancer Institute

Volumn 88, Issue 8, 1996, Pages 550-552

  Cangiano, Carlo ^a   Laviano, Alessandro ^a   Meguid, Michael M ^b   Mulieri, Massimo ^c   Conversano, Laura ^a   Preziosa, Isabella ^a   Rossi Fanelli, Filippo ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^c Ist per Diagnosi Cura T   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRANCHED CHAIN AMINO ACID; SEROTONIN; TRYPTOPHAN;

ADULT; AGED; AMINO ACID METABOLISM; ANOREXIA; ARTICLE; CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MALE; MALNUTRITION; ORAL DRUG ADMINISTRATION; PROTEIN INTAKE; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; AMINO ACIDS, BRANCHED-CHAIN; ANOREXIA; DOUBLE-BLIND METHOD; ENERGY INTAKE; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS;

EID: 0029964211     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/88.8.550     Document Type: Article

References (11)

1. Langstein HN, Norton JA. Mechanisms of cancer cachexia. Hematol Oncol Clin North Am 1991.5:103-23.
2. Krause R, James JH, Ziparo V, Fisher JE. Brain tryptophan and the neoplastic anorexia-cachexia syndrome. Cancer 1979;44: 1003-108.
3. Meguid MM, Muscaritoli M, Beverly JL, Yang ZJ, Cangiano C, Rossi-Fanelli F. The early cancer anorexia paradigm: changes in plasma free tryptophan and feeding indexes. J Parenter Enterai Nutr 1992;16:56S-59S.
4. Fanelli FR, Cangiano C, Ceci F, Cellerino R, Franchi F. Menichetti ET, et al. Plasma tryptophan and anorexia m human cancer. Eur J Cancer Clin Oncol 1986;22:89-95.
5. Cangiano C, Cascino A, Ceci F, Laviano A, Mulieri M, Muscaritoli M, et al. Plasma and CSF tryptophan in cancer anorexia. J Neural Transm Gen Sect 1990;81:225-33.
6. Cangiano C, Testa U, Muscaritoli M, Meguid MM, Mulieri M, Laviano A, et al. Cytokines, tryptophan and anorexia in cancer patients before and after surgical tumor ablation. Anticancer Res 1994;14:1451-5.
7. Rossi-Fanelli F, Cascino A, Strom R, Cardelli-Cangiano P. Ceci F, Muscaritoli M, et al. Amino acids and hepatic encephalopathy. Prog Neurobiol 1987;28:277-301.
8. Tchekmedyian NS. Zahyna D, Halpert C, Heber D. Clinical aspects of nutrition in advanced cancer. Oncology 1992;49 Suppl 2:3-7.
9. Ovesen L, Hannibal J, Mortensen EL.The interrelationship of weight loss, dietary intake, and quality of life in ambulatory patients with cancer of the lung, breast, and ovary. Nutr Cancer 1993;19:159-67.
10. Lopnnzi CL, Goldberg RM, Burnham NL. Cancer-associated anorexia and cachexia. Implications for drug therapy. Drugs 1992; 43:499-506.
11. Rossi-Fanelli F. Cangiano C. Increased availability of tryptophan in the brain as a common pathogenic mechanism for anorexia associated with different diseases. Nutrition 1991;7:364-7.