메뉴 건너뛰기




Volumn 71, Issue 6, 2011, Pages 815-823

Understanding the time course of pharmacological effect: A PKPD approach

Author keywords

Population pharmacokinetic pharmacodynamic models

Indexed keywords

BLOOD CLOTTING FACTOR; DABIGATRAN; DICLOFENAC; FENTANYL; SIMVASTATIN; SOTALOL; THEOPHYLLINE; TUBOCURARINE CHLORIDE; WARFARIN;

EID: 79955825778     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2011.03925.x     Document Type: Article
Times cited : (69)

References (38)
  • 1
    • 0000871885 scopus 로고
    • The scientific status of pharmacology
    • Leake CD. The scientific status of pharmacology. Science 1961; 134: 2069-79.
    • (1961) Science , vol.134 , pp. 2069-2079
    • Leake, C.D.1
  • 2
    • 0032777807 scopus 로고    scopus 로고
    • Clinical pharmacology: the scientific basis of therapeutics
    • Reidenberg MM. Clinical pharmacology: the scientific basis of therapeutics. Clin Pharmacol Ther 1999; 66: 2-8.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 2-8
    • Reidenberg, M.M.1
  • 3
    • 33847028671 scopus 로고    scopus 로고
    • Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis
    • Danhof M, de Jongh J, De Lange ECM, Della Pasqua O, Ploeger BA, Voskuyl RA. Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis. Annu Rev Pharmacol Toxicol 2007; 47: 357-400.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 357-400
    • Danhof, M.1    de Jongh, J.2    De Lange, E.C.M.3    Della Pasqua, O.4    Ploeger, B.A.5    Voskuyl, R.A.6
  • 4
    • 0034119297 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic modeling in drug development
    • Sheiner LB, Steimer JL. Pharmacokinetic/pharmacodynamic modeling in drug development. Annu Rev Pharmacol Toxicol 2000; 40: 67-95.
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 67-95
    • Sheiner, L.B.1    Steimer, J.L.2
  • 5
    • 79955844576 scopus 로고    scopus 로고
    • Interpreting population pharmacokinetic-pharmacodynamic analyses - a clinical viewpoint
    • DOI: 10.1111/j.1365-2125.2010.03891.x.
    • Duffull SB, Wright DFB, Winter HR. Interpreting population pharmacokinetic-pharmacodynamic analyses - a clinical viewpoint. Br J Clin Pharmacol 2011; DOI: 10.1111/j.1365-2125.2010.03891.x.
    • (2011) Br J Clin Pharmacol
    • Duffull, S.B.1    Wright, D.F.B.2    Winter, H.R.3
  • 6
    • 30544454555 scopus 로고    scopus 로고
    • Recommended reading in population pharmacokinetic pharmacodynamics
    • Bonate PL. Recommended reading in population pharmacokinetic pharmacodynamics. AAPS J 2005; 7: E363-73.
    • (2005) AAPS J , vol.7
    • Bonate, P.L.1
  • 9
    • 0031691162 scopus 로고    scopus 로고
    • Expanding clinical applications of population pharmacodynamic modelling
    • Minto C, Schnider T. Expanding clinical applications of population pharmacodynamic modelling. Br J Clin Pharmacol 1998; 46: 321-33.
    • (1998) Br J Clin Pharmacol , vol.46 , pp. 321-333
    • Minto, C.1    Schnider, T.2
  • 10
    • 4644293405 scopus 로고    scopus 로고
    • Population pharmacokinetics I: background, concepts, and models
    • Ette EI, Williams PJ. Population pharmacokinetics I: background, concepts, and models. Ann Pharmacother 2004; 38: 1702-6.
    • (2004) Ann Pharmacother , vol.38 , pp. 1702-1706
    • Ette, E.I.1    Williams, P.J.2
  • 11
    • 0019785890 scopus 로고
    • Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models
    • Holford NH, Sheiner LB. Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models. Clin Pharmacokinet 1981; 6: 429-53.
    • (1981) Clin Pharmacokinet , vol.6 , pp. 429-453
    • Holford, N.H.1    Sheiner, L.B.2
  • 12
    • 33846334827 scopus 로고    scopus 로고
    • Modellling response time profile in the absence of drug concentrations: definition and performance evaluation of the PK-PD model
    • Jacqmin P, Snoeck E, van Schaick E, Gieschke R, Pillai P, Steimer J, Girard P. Modellling response time profile in the absence of drug concentrations: definition and performance evaluation of the PK-PD model. J Pharmacokinet Pharmacodyn 2007; 34: 57-85.
    • (2007) J Pharmacokinet Pharmacodyn , vol.34 , pp. 57-85
    • Jacqmin, P.1    Snoeck, E.2    van Schaick, E.3    Gieschke, R.4    Pillai, P.5    Steimer, J.6    Girard, P.7
  • 13
    • 0027049043 scopus 로고
    • Building population pharmacokinetic - pharmacodynamic models. I. Models for covariate effects
    • Mandema JW, Verotta D, Sheiner LB. Building population pharmacokinetic - pharmacodynamic models. I. Models for covariate effects. J Pharmacokinet Biopharm 1992; 20: 511-28.
    • (1992) J Pharmacokinet Biopharm , vol.20 , pp. 511-528
    • Mandema, J.W.1    Verotta, D.2    Sheiner, L.B.3
  • 14
    • 34250632673 scopus 로고    scopus 로고
    • Introduction of quantitative methods in pharmacology and clinical pharmacology: a historical overview
    • Atkinson AJ Jr, Lalonde RL. Introduction of quantitative methods in pharmacology and clinical pharmacology: a historical overview. Clin Pharmacol Ther 2007; 82: 3-6.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 3-6
    • Atkinson Jr, A.J.1    Lalonde, R.L.2
  • 15
    • 0020315441 scopus 로고
    • Kinetics of pharmacologic response
    • Holford NH, Sheiner LB. Kinetics of pharmacologic response. Pharmacol Ther 1982; 16: 143-66.
    • (1982) Pharmacol Ther , vol.16 , pp. 143-166
    • Holford, N.H.1    Sheiner, L.B.2
  • 16
    • 0018394195 scopus 로고
    • Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine
    • Sheiner LB, Stanski DR, Vozeh S, Miller RD, Ham J. Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther 1979; 25: 358-71.
    • (1979) Clin Pharmacol Ther , vol.25 , pp. 358-371
    • Sheiner, L.B.1    Stanski, D.R.2    Vozeh, S.3    Miller, R.D.4    Ham, J.5
  • 17
    • 79955821784 scopus 로고    scopus 로고
    • Clinical Pharmacokinetics
    • In:, 2nd edn, eds Atkinson A, Abernethy D, Daniels C, Dedrick R, Markey S. New York, NY: Academic Press
    • Atkinson AJ. Clinical Pharmacokinetics. In: Principles of Clinical Pharmacology, 2nd edn, eds Atkinson A, Abernethy D, Daniels C, Dedrick R, Markey S. New York, NY: Academic Press, 2007; 11-23.
    • (2007) Principles of Clinical Pharmacology , pp. 11-23
    • Atkinson, A.J.1
  • 18
    • 77953507378 scopus 로고    scopus 로고
    • The 'apparent clearance' of free phenytoin in elderly vs. younger adults
    • Wright DFB, Begg EJ. The 'apparent clearance' of free phenytoin in elderly vs. younger adults. Br J Clin Pharmacol 2010; 70: 132-38.
    • (2010) Br J Clin Pharmacol , vol.70 , pp. 132-138
    • Wright, D.F.B.1    Begg, E.J.2
  • 20
    • 34848925807 scopus 로고    scopus 로고
    • Red blood cell methotrexate polyglutamate concentrations in inflammatory bowel disease
    • Brooks AJ, Begg EJ, Zhang M, Frampton CM, Barclay ML. Red blood cell methotrexate polyglutamate concentrations in inflammatory bowel disease. Ther Drug Monit 2007; 29: 619-25.
    • (2007) Ther Drug Monit , vol.29 , pp. 619-625
    • Brooks, A.J.1    Begg, E.J.2    Zhang, M.3    Frampton, C.M.4    Barclay, M.L.5
  • 21
    • 0002838483 scopus 로고    scopus 로고
    • Drug Receptors and Pharmacodynamics
    • In:, 8th edn, ed. Katzung BG. New York, NY: McGraw-Hill
    • Bourne HR, von Zastrow M. Drug Receptors and Pharmacodynamics. In: Basic and Clinical Pharmacology, 8th edn, ed. Katzung BG. New York, NY: McGraw-Hill, 2001; 9-34.
    • (2001) Basic and Clinical Pharmacology , pp. 9-34
    • Bourne, H.R.1    von Zastrow, M.2
  • 22
    • 33745792813 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic modelling: history and perspectives
    • Csajka C, Verotta D. Pharmacokinetic-pharmacodynamic modelling: history and perspectives. J Pharmacokinet Pharmacodyn 2006; 33: 227-79.
    • (2006) J Pharmacokinet Pharmacodyn , vol.33 , pp. 227-279
    • Csajka, C.1    Verotta, D.2
  • 24
    • 0018749685 scopus 로고
    • Fractionation of low molecular weight heparin species and their interaction with antithrombin
    • Beeler D, Rosenberg R, Jordan R. Fractionation of low molecular weight heparin species and their interaction with antithrombin. J Biol Chem 1979; 254: 2902-13.
    • (1979) J Biol Chem , vol.254 , pp. 2902-2913
    • Beeler, D.1    Rosenberg, R.2    Jordan, R.3
  • 25
    • 33750023407 scopus 로고    scopus 로고
    • Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis
    • Liesenfeld KH, Schäfer HG, Trocóniz IF, Tillmann C, Eriksson BI, Stangier J. Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis. Br J Clin Pharmacol 2006; 62: 527-37.
    • (2006) Br J Clin Pharmacol , vol.62 , pp. 527-537
    • Liesenfeld, K.H.1    Schäfer, H.G.2    Trocóniz, I.F.3    Tillmann, C.4    Eriksson, B.I.5    Stangier, J.6
  • 27
    • 0033859564 scopus 로고    scopus 로고
    • Review article: comparison of the pharmacokinetics, acid suppression and efficacy of proton pump inhibitors
    • Stedman CA, Barclay ML. Review article: comparison of the pharmacokinetics, acid suppression and efficacy of proton pump inhibitors. Aliment Pharmacol Ther 2000; 14: 963-78.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 963-978
    • Stedman, C.A.1    Barclay, M.L.2
  • 28
    • 33846012170 scopus 로고    scopus 로고
    • Mechanism-based PK/PD modeling of the respiratory depressant effect of buprenorphine and fentanyl in healthy volunteers
    • Yassen A, Olofsen E, Romberg R, Sarton E, Teppema L, Danhof M, Dahan A. Mechanism-based PK/PD modeling of the respiratory depressant effect of buprenorphine and fentanyl in healthy volunteers. Clin Pharmacol Ther 2007; 81: 50-8.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 50-58
    • Yassen, A.1    Olofsen, E.2    Romberg, R.3    Sarton, E.4    Teppema, L.5    Danhof, M.6    Dahan, A.7
  • 29
    • 0030869429 scopus 로고    scopus 로고
    • A pharmacokinetic-pharmacodynamic model of d-sotalol Q-Tc prolongation during intravenous administration to healthy subjects
    • Salazar DE, Much DR, Nichola PS, Seibold JR, Shindler D, Slugg PH. A pharmacokinetic-pharmacodynamic model of d-sotalol Q-Tc prolongation during intravenous administration to healthy subjects. J Clin Pharmacol 1997; 37: 799-809.
    • (1997) J Clin Pharmacol , vol.37 , pp. 799-809
    • Salazar, D.E.1    Much, D.R.2    Nichola, P.S.3    Seibold, J.R.4    Shindler, D.5    Slugg, P.H.6
  • 30
    • 0037357257 scopus 로고    scopus 로고
    • Intravenously administered digoxin in patients with acute atrial fibrillation: a population pharmacokinetic/pharmacodynamic analysis based on the Digitalis in Acute Atrial Fibrillation trial
    • Hornestam B, Jerling M, Karlsson MO, Held P, Group DAT. Intravenously administered digoxin in patients with acute atrial fibrillation: a population pharmacokinetic/pharmacodynamic analysis based on the Digitalis in Acute Atrial Fibrillation trial. Eur J Clin Pharmacol 2003; 58: 747-55.
    • (2003) Eur J Clin Pharmacol , vol.58 , pp. 747-755
    • Hornestam, B.1    Jerling, M.2    Karlsson, M.O.3    Held, P.4    Group, D.A.T.5
  • 31
    • 0031890386 scopus 로고    scopus 로고
    • Characteristics of indirect pharmacodynamic models and applications to clinical drug responses
    • Sharma A, Jusko WJ. Characteristics of indirect pharmacodynamic models and applications to clinical drug responses. Br J Clin Pharmacol 1998; 45: 229-39.
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 229-239
    • Sharma, A.1    Jusko, W.J.2
  • 32
    • 0027943266 scopus 로고
    • Physiologic indirect response models characterize diverse types of pharmacodynamic effects
    • Jusko WJ, Ko HC. Physiologic indirect response models characterize diverse types of pharmacodynamic effects. Clin Pharmacol Ther 1994; 56: 406-19.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 406-419
    • Jusko, W.J.1    Ko, H.C.2
  • 33
    • 0027769745 scopus 로고
    • Comparison of four basic models of indirect pharmacodynamic responses
    • Dayneka NL, Garg V, Jusko WJ. Comparison of four basic models of indirect pharmacodynamic responses. J Pharmacokinet Biopharm 1993; 21: 457-78.
    • (1993) J Pharmacokinet Biopharm , vol.21 , pp. 457-478
    • Dayneka, N.L.1    Garg, V.2    Jusko, W.J.3
  • 35
    • 0033501265 scopus 로고    scopus 로고
    • Application of a combined 'effect compartment/indirect response model' to the central nervous system effects of tiagabine in the rat
    • Cleton A, de Greef HJ, Edelbroek PM, Voskuyl RA, Danhof M. Application of a combined 'effect compartment/indirect response model' to the central nervous system effects of tiagabine in the rat. J Pharmacokinet Biopharm 1999; 27: 301-23.
    • (1999) J Pharmacokinet Biopharm , vol.27 , pp. 301-323
    • Cleton, A.1    de Greef, H.J.2    Edelbroek, P.M.3    Voskuyl, R.A.4    Danhof, M.5
  • 36
    • 79955601805 scopus 로고
    • Rational warfarin dosing: a pharmacokinetic-pharmacodynamic analysis
    • Holford NH. Rational warfarin dosing: a pharmacokinetic-pharmacodynamic analysis. Clin Pharmacol Ther 1986; 39: 199.
    • (1986) Clin Pharmacol Ther , vol.39 , pp. 199
    • Holford, N.H.1
  • 37
    • 75449125272 scopus 로고
    • Studies on the coumadin anticoagulant drugs: the pharmacodynamics of warfarin in man
    • O'Reilly RA, Aggeler PM, Leong LS. Studies on the coumadin anticoagulant drugs: the pharmacodynamics of warfarin in man. J Clin Invest 1963; 42: 1542-51.
    • (1963) J Clin Invest , vol.42 , pp. 1542-1551
    • O'Reilly, R.A.1    Aggeler, P.M.2    Leong, L.S.3
  • 38
    • 0014314758 scopus 로고
    • Studies on coumarin anticoagulant drugs. Initiation of warfarin therapy without a loading dose
    • O'Reilly RA, Aggeler PM. Studies on coumarin anticoagulant drugs. Initiation of warfarin therapy without a loading dose. Circulation 1968; 38: 169-77.
    • (1968) Circulation , vol.38 , pp. 169-177
    • O'Reilly, R.A.1    Aggeler, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.