메뉴 건너뛰기




Volumn 99, Issue 5, 2008, Pages 807-818

Heparin and low-molecular-weight heparin

Author keywords

Heparin; Low molecular weight heparin

Indexed keywords

BEMIPARIN; DALTEPARIN; DEXTRAN; ENOXAPARIN; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; PARNAPARIN; REVIPARIN; THROMBIN; TINZAPARIN; WARFARIN;

EID: 43949084693     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH08-01-0032     Document Type: Review
Times cited : (257)

References (133)
  • 1
    • 0034533546 scopus 로고    scopus 로고
    • Characterisation of unfractionated heparin samples: Comparison of samples from the last 50 years
    • Mulloy B, Gray E, Barrowcliffe TW. Characterisation of unfractionated heparin samples: Comparison of samples from the last 50 years". Thromb Haemost 2000; 84: 1052-1056.
    • (2000) Thromb Haemost , vol.84 , pp. 1052-1056
    • Mulloy, B.1    Gray, E.2    Barrowcliffe, T.W.3
  • 2
    • 0345079919 scopus 로고    scopus 로고
    • The inhibition of blood coagulation by heparins of different molecular weight is caused by a common functional motif - the C-domain
    • Al Dieri R, Wagenvoord R, van Dedem GW, et al. The inhibition of blood coagulation by heparins of different molecular weight is caused by a common functional motif - the C-domain. J Thromb Haemost 2003; 1: 907-914.
    • (2003) J Thromb Haemost , vol.1 , pp. 907-914
    • Al Dieri, R.1    Wagenvoord, R.2    van Dedem, G.W.3
  • 3
    • 33748164423 scopus 로고    scopus 로고
    • Glycomics approach to structure-function relationships of glycosaminoglycans
    • Sasisekharan R, Raman R, Prabhakar V. Glycomics approach to structure-function relationships of glycosaminoglycans. Annu Rev Biomed Eng 2006; 8: 181-231.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 181-231
    • Sasisekharan, R.1    Raman, R.2    Prabhakar, V.3
  • 4
    • 0034775821 scopus 로고    scopus 로고
    • Combined quantitative (1)H and (13)C nuclear magnetic resonance spectroscopy for characterization of heparin preparations
    • Guerrini M, Bisio A, Torri G. Combined quantitative (1)H and (13)C nuclear magnetic resonance spectroscopy for characterization of heparin preparations. Semin Thromb Hemost 2001; 27: 473-482.
    • (2001) Semin Thromb Hemost , vol.27 , pp. 473-482
    • Guerrini, M.1    Bisio, A.2    Torri, G.3
  • 5
    • 0035799391 scopus 로고    scopus 로고
    • Antithrombin binding of low molecular weight heparins and inhibition of factor Xa
    • Lin P-H, Sinha U, Betz A. Antithrombin binding of low molecular weight heparins and inhibition of factor Xa. Biochim Biophys Acta 2001; 1526: 105-113.
    • (2001) Biochim Biophys Acta , vol.1526 , pp. 105-113
    • Lin, P.-H.1    Sinha, U.2    Betz, A.3
  • 6
    • 43949104663 scopus 로고    scopus 로고
    • Monograph 01/2008:0828 Heparins, Low-Molecular_ mass, European Pharmacopoeia 2008; Edition 6.0: 2041-2042.
    • Monograph 01/2008:0828 Heparins, Low-Molecular_ mass, European Pharmacopoeia 2008; Edition 6.0: 2041-2042.
  • 7
    • 0030891052 scopus 로고    scopus 로고
    • Molecular weight measurements of low molecular weight heparins by gel permeation chromatography
    • Mulloy B, Gee C, Wheeler S, et al. Molecular weight measurements of low molecular weight heparins by gel permeation chromatography. Thromb Haemost 1997; 77: 668-674.
    • (1997) Thromb Haemost , vol.77 , pp. 668-674
    • Mulloy, B.1    Gee, C.2    Wheeler, S.3
  • 8
    • 0017071804 scopus 로고
    • Four heparin preparations: Anti-Xa potentiating effect of heparin after subcutaneous injection
    • Johnson EA, Kirkwood TB, Stirling Y, et al. Four heparin preparations: anti-Xa potentiating effect of heparin after subcutaneous injection. Thromb Haemost 1976; 35: 586-591.
    • (1976) Thromb Haemost , vol.35 , pp. 586-591
    • Johnson, E.A.1    Kirkwood, T.B.2    Stirling, Y.3
  • 9
    • 0032745131 scopus 로고    scopus 로고
    • Production and chemical processing of low molecular weight heparins
    • Linhardt RJ, Gunay NS. Production and chemical processing of low molecular weight heparins. Semin Thromb Haemost 1999; 25 (Suppl 3): 5-16.
    • (1999) Semin Thromb Haemost , vol.25 , Issue.SUPPL. 3 , pp. 5-16
    • Linhardt, R.J.1    Gunay, N.S.2
  • 10
    • 0016433560 scopus 로고
    • Actions and interactions of antithrombin and heparin
    • Rosenberg RD. Actions and interactions of antithrombin and heparin. New Engl J Med 1975; 292: 146-151.
    • (1975) New Engl J Med , vol.292 , pp. 146-151
    • Rosenberg, R.D.1
  • 11
    • 0017074450 scopus 로고
    • Anticoagulant activity of heparin: Separation of high-activity and low-activity heparin species by affinity chromatography on immobilized antithrombin
    • Hook M, Bjork I, Hopwood J, et al. Anticoagulant activity of heparin: separation of high-activity and low-activity heparin species by affinity chromatography on immobilized antithrombin. FEBS Lett. 1976; 66: 90-93.
    • (1976) FEBS Lett , vol.66 , pp. 90-93
    • Hook, M.1    Bjork, I.2    Hopwood, J.3
  • 12
    • 0021061174 scopus 로고
    • Structure-activity relationship in heparin: A synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity
    • Choay J, Petitou M, Lormeau JC, et al. Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity. Biochem Biophys Res Commun 1983; 116: 492-499.
    • (1983) Biochem Biophys Res Commun , vol.116 , pp. 492-499
    • Choay, J.1    Petitou, M.2    Lormeau, J.C.3
  • 13
    • 0017044123 scopus 로고
    • Anticoagulant properties of heparin fractionated by affinity chromatography on matrix-bound antithrombin III and by gel filtration
    • Andersson LO, Barrowcliffe TW, Holmer E, et al. Anticoagulant properties of heparin fractionated by affinity chromatography on matrix-bound antithrombin III and by gel filtration. Thromb Res 1976; 9: 575-583.
    • (1976) Thromb Res , vol.9 , pp. 575-583
    • Andersson, L.O.1    Barrowcliffe, T.W.2    Holmer, E.3
  • 14
    • 0017874792 scopus 로고
    • Anticoagulant activities of four unfractionated and fractionated heparins
    • Lane DA, Macgregor IR, Michalski R, et al. Anticoagulant activities of four unfractionated and fractionated heparins. Thromb Res 1978; 12: 257-271.
    • (1978) Thromb Res , vol.12 , pp. 257-271
    • Lane, D.A.1    Macgregor, I.R.2    Michalski, R.3
  • 15
    • 0018770761 scopus 로고
    • Anticoagulant activities of high and low molecular weight heparin fractions
    • Barrowcliffe TW, Johnson EA, Eggleton CA, et al. Anticoagulant activities of high and low molecular weight heparin fractions. Br J Haematol 1979; 41: 573-583.
    • (1979) Br J Haematol , vol.41 , pp. 573-583
    • Barrowcliffe, T.W.1    Johnson, E.A.2    Eggleton, C.A.3
  • 16
    • 0018973385 scopus 로고
    • Anticoagulant activities and effects on platelets of a heparin fragment with high affinity for antithrombin
    • Holmer E, Lindahl U, Backstrom G, et al. Anticoagulant activities and effects on platelets of a heparin fragment with high affinity for antithrombin. Thromb Res 1980; 18: 861-869.
    • (1980) Thromb Res , vol.18 , pp. 861-869
    • Holmer, E.1    Lindahl, U.2    Backstrom, G.3
  • 17
    • 0019953801 scopus 로고
    • Effects of heparin oligosaccharides with high affinity for antithrombin III in experimental venous thrombosis
    • Thomas DP, Merton RE, Barrowcliffe TW, et al. Effects of heparin oligosaccharides with high affinity for antithrombin III in experimental venous thrombosis. Thromb Haemost 1982; 47: 244-248.
    • (1982) Thromb Haemost , vol.47 , pp. 244-248
    • Thomas, D.P.1    Merton, R.E.2    Barrowcliffe, T.W.3
  • 18
    • 0021268420 scopus 로고
    • Low-affinity heparin potentiates the action of high-affinity heparin oligosaccharides
    • Barrowcliffe TW, Merton RE, Havercroft SJ, et al. Low-affinity heparin potentiates the action of high-affinity heparin oligosaccharides. Thromb Res 1984; 34: 125-133.
    • (1984) Thromb Res , vol.34 , pp. 125-133
    • Barrowcliffe, T.W.1    Merton, R.E.2    Havercroft, S.J.3
  • 19
    • 0021344246 scopus 로고
    • Anticoagulant activities of heparin oligosaccharides and their neutralization by platelet factor 4
    • Lane DA, Denton J, Flynn AM, et al. Anticoagulant activities of heparin oligosaccharides and their neutralization by platelet factor 4. Biochem J 1984; 218: 725-732.
    • (1984) Biochem J , vol.218 , pp. 725-732
    • Lane, D.A.1    Denton, J.2    Flynn, A.M.3
  • 20
    • 0018179416 scopus 로고
    • A catalytic role for heparin. Evidence for a ternary complex of heparin cofactor thrombin and heparin
    • Pomerantz MW, Owen WG. A catalytic role for heparin. Evidence for a ternary complex of heparin cofactor thrombin and heparin. Biochim Biophys Acta 1978; 535: 66-77.
    • (1978) Biochim Biophys Acta , vol.535 , pp. 66-77
    • Pomerantz, M.W.1    Owen, W.G.2
  • 21
    • 0021363605 scopus 로고
    • Involvement of heparin chain length in the heparin-catalyzed inhibition of thrombin by antithrombin III
    • Hoylaerts M, Owen WG, Collen D. Involvement of heparin chain length in the heparin-catalyzed inhibition of thrombin by antithrombin III. J Biol Chem 1984; 259: 5670-5677.
    • (1984) J Biol Chem , vol.259 , pp. 5670-5677
    • Hoylaerts, M.1    Owen, W.G.2    Collen, D.3
  • 22
    • 0022521379 scopus 로고
    • The relative molecular mass dependence of the anti-factor Xa properties of heparin
    • Ellis V, Scully MF, Kakkar VV. The relative molecular mass dependence of the anti-factor Xa properties of heparin. Biochem J 1986; 238: 329-333.
    • (1986) Biochem J , vol.238 , pp. 329-333
    • Ellis, V.1    Scully, M.F.2    Kakkar, V.V.3
  • 23
    • 0024408690 scopus 로고
    • The effect of calcium chloride on anti-Xa activity of heparin and its molecular weight fractions
    • Barrowcliffe TW, Le Shirley Y. The effect of calcium chloride on anti-Xa activity of heparin and its molecular weight fractions. Thromb Haemost 1989; 62: 950-954.
    • (1989) Thromb Haemost , vol.62 , pp. 950-954
    • Barrowcliffe, T.W.1    Le Shirley, Y.2
  • 24
    • 43949144143 scopus 로고    scopus 로고
    • Linear diffusion of thrombin and factor Xa along the heparin molecule explains the effects of extended heparin chain lengths
    • in press
    • Wagenvoord R, Al Dieri R, van Dedem G, et al. Linear diffusion of thrombin and factor Xa along the heparin molecule explains the effects of extended heparin chain lengths. Thromb Res 2008; in press.
    • (2008) Thromb Res
    • Wagenvoord, R.1    Al Dieri, R.2    van Dedem, G.3
  • 25
    • 0023160749 scopus 로고
    • The effect of Ca2+, phospholipid and factor V on the anti-(factor Xa) activity of heparin and its high-affinity oligosaccharides
    • Barrowcliffe TW, Havercroft SJ, Kemball-Cook G, et al. The effect of Ca2+, phospholipid and factor V on the anti-(factor Xa) activity of heparin and its high-affinity oligosaccharides. Biochem J 1987; 243: 31-37.
    • (1987) Biochem J , vol.243 , pp. 31-37
    • Barrowcliffe, T.W.1    Havercroft, S.J.2    Kemball-Cook, G.3
  • 26
    • 0022453337 scopus 로고
    • The acceleration of the inhibition of platelet prothrombinase complex by heparin
    • Ellis V, Scully MF, Kakkar VV. The acceleration of the inhibition of platelet prothrombinase complex by heparin. Biochem J 1986; 233: 161-165.
    • (1986) Biochem J , vol.233 , pp. 161-165
    • Ellis, V.1    Scully, M.F.2    Kakkar, V.V.3
  • 27
    • 0028641605 scopus 로고
    • Heparin and low molecular weight heparins inhibit prothrombinase formation but not its activity in plasma
    • Ofosu FA, Lormeau JC, Craven S, et al. Heparin and low molecular weight heparins inhibit prothrombinase formation but not its activity in plasma. Thromb Haemost 1994; 72: 862-828.
    • (1994) Thromb Haemost , vol.72 , pp. 862-828
    • Ofosu, F.A.1    Lormeau, J.C.2    Craven, S.3
  • 28
    • 0019499060 scopus 로고
    • The molecular-weight dependence of the rate-enhancing effect of heparin on the inhibition of thrombin, factor Xa, factor IXa, factor XIa, factor XIIa and kallikrein by antithrombin
    • Holmer E, Kurachi K, Söderström G. The molecular-weight dependence of the rate-enhancing effect of heparin on the inhibition of thrombin, factor Xa, factor IXa, factor XIa, factor XIIa and kallikrein by antithrombin. Biochem J 1981; 193: 395-400.
    • (1981) Biochem J , vol.193 , pp. 395-400
    • Holmer, E.1    Kurachi, K.2    Söderström, G.3
  • 29
    • 0024390492 scopus 로고
    • Effect of heparin on the inhibition of the contact system enzymes
    • Colman RW, Scott CF, Pixley RA, et al. Effect of heparin on the inhibition of the contact system enzymes. Ann NY Acad Sci 1989; 556: 95-103.
    • (1989) Ann NY Acad Sci , vol.556 , pp. 95-103
    • Colman, R.W.1    Scott, C.F.2    Pixley, R.A.3
  • 30
    • 0021853943 scopus 로고
    • The importance of thrombin inhibition for the expression of the anticoagulant activities of heparin, dermatan sulphate, low molecular weight heparin and pentosan polysulphate
    • Ofosu FA, Blajchman MA, Modi GJ, et al. The importance of thrombin inhibition for the expression of the anticoagulant activities of heparin, dermatan sulphate, low molecular weight heparin and pentosan polysulphate. Br J Haematol 1985; 60: 695-704.
    • (1985) Br J Haematol , vol.60 , pp. 695-704
    • Ofosu, F.A.1    Blajchman, M.A.2    Modi, G.J.3
  • 31
    • 0024528023 scopus 로고
    • Unfractionated heparin inhibits thrombin-catalysed amplification reactions of coagulation more efficiently than those catalysed by factor Xa
    • Ofosu FA, Hirsh J, Esmon CT, et al. Unfractionated heparin inhibits thrombin-catalysed amplification reactions of coagulation more efficiently than those catalysed by factor Xa. Biochem J 1989; 257: 143-150.
    • (1989) Biochem J , vol.257 , pp. 143-150
    • Ofosu, F.A.1    Hirsh, J.2    Esmon, C.T.3
  • 32
    • 0025106352 scopus 로고
    • Mechanisms of action of low molecular weight heparins and heparinoids
    • Ofosu FA, Barrowcliffe TW. Mechanisms of action of low molecular weight heparins and heparinoids. Baillieres Clin Haematol 1990; 3: 505-529.
    • (1990) Baillieres Clin Haematol , vol.3 , pp. 505-529
    • Ofosu, F.A.1    Barrowcliffe, T.W.2
  • 33
    • 0024400139 scopus 로고
    • Anticoagulant activities of heparin and fragments
    • Barrowcliffe TW, Thomas DP. Anticoagulant activities of heparin and fragments. Ann NY Acad Sci 1989; 556: 132-145.
    • (1989) Ann NY Acad Sci , vol.556 , pp. 132-145
    • Barrowcliffe, T.W.1    Thomas, D.P.2
  • 34
    • 0024582005 scopus 로고
    • The relative antithrombotic effectiveness of heparin, a low molecular weight heparin, and a pentasaccharide fragment in an animal model
    • Thomas DP, Merton RE, Gray E, et al. The relative antithrombotic effectiveness of heparin, a low molecular weight heparin, and a pentasaccharide fragment in an animal model. Thromb Haemost 1989; 61: 204-207.
    • (1989) Thromb Haemost , vol.61 , pp. 204-207
    • Thomas, D.P.1    Merton, R.E.2    Gray, E.3
  • 36
    • 0024339952 scopus 로고
    • The action of a synthetic pentasaccharide on thrombin generation in whole plasma
    • Béguin S, Choay J, Hemker HC. The action of a synthetic pentasaccharide on thrombin generation in whole plasma. Thromb Haemost 1989; 61: 397-401.
    • (1989) Thromb Haemost , vol.61 , pp. 397-401
    • Béguin, S.1    Choay, J.2    Hemker, H.C.3
  • 37
    • 0027377650 scopus 로고
    • Continuous registration of thrombin generation in plasma, its use for the determination of the thrombin potential
    • Hemker HC, Wielders S, Kessels H, et al. Continuous registration of thrombin generation in plasma, its use for the determination of the thrombin potential. Thromb Haemost 1993; 70: 617-624.
    • (1993) Thromb Haemost , vol.70 , pp. 617-624
    • Hemker, H.C.1    Wielders, S.2    Kessels, H.3
  • 38
    • 0024563615 scopus 로고
    • The mode of action of low molecular weight heparin preparation (PK10169) and two of its major components on thrombin generation in plasma
    • Béguin S, Mardiguian J, Lindhout T, et al. The mode of action of low molecular weight heparin preparation (PK10169) and two of its major components on thrombin generation in plasma. Thromb Haemost 1989; 61: 30-34.
    • (1989) Thromb Haemost , vol.61 , pp. 30-34
    • Béguin, S.1    Mardiguian, J.2    Lindhout, T.3
  • 39
    • 0025142644 scopus 로고
    • Is anti-factor Xa activity important?
    • Hemker HC. Is anti-factor Xa activity important? J Lab Clin Med 1990; 116: 268.
    • (1990) J Lab Clin Med , vol.116 , pp. 268
    • Hemker, H.C.1
  • 40
    • 0027527403 scopus 로고
    • The activity of heparin in the presence and absence of Ca2+ ions; why the anti-Xa activity of LMWHs is about two times overestimated
    • Hemker HC, Béguin S. The activity of heparin in the presence and absence of Ca2+ ions; why the anti-Xa activity of LMWHs is about two times overestimated. Thromb Haemost 1993; 70: 717-718.
    • (1993) Thromb Haemost , vol.70 , pp. 717-718
    • Hemker, H.C.1    Béguin, S.2
  • 42
    • 0019953801 scopus 로고
    • Effects of heparin oligosaccharides with high affinity for antithrombin III in experimental venous thrombosis
    • Thomas DP, Merton RE, Barrowcliffe TW, et al. Effects of heparin oligosaccharides with high affinity for antithrombin III in experimental venous thrombosis. Thromb Haemost 1982; 47: 244-248.
    • (1982) Thromb Haemost , vol.47 , pp. 244-248
    • Thomas, D.P.1    Merton, R.E.2    Barrowcliffe, T.W.3
  • 43
    • 0036834207 scopus 로고    scopus 로고
    • Fondaparinux: Basic properties and efficacy and safety in venous thromboembolism prophylaxis
    • Bauer KA. Fondaparinux: basic properties and efficacy and safety in venous thromboembolism prophylaxis. Am J Orthop 2002; 31 (11 Suppl): 4-10.
    • (2002) Am J Orthop , vol.31 , Issue.11 SUPPL. , pp. 4-10
    • Bauer, K.A.1
  • 44
    • 0037239007 scopus 로고    scopus 로고
    • Evaluation of the pharmacological properties and clinical results of the synthetic pentasaccharide (fondaparinux)
    • Samama MM, Gerotziafas GT. Evaluation of the pharmacological properties and clinical results of the synthetic pentasaccharide (fondaparinux). Thromb Res 2003; 109: 1-11.
    • (2003) Thromb Res , vol.109 , pp. 1-11
    • Samama, M.M.1    Gerotziafas, G.T.2
  • 47
    • 0022409411 scopus 로고
    • Standardization of low molecular weight heparins: A collaborative study
    • Barrowcliffe TW, Curtis AD, Tomlinson TP, et al. Standardization of low molecular weight heparins: a collaborative study. Thromb Haemost 1985; 54: 675-679.
    • (1985) Thromb Haemost , vol.54 , pp. 675-679
    • Barrowcliffe, T.W.1    Curtis, A.D.2    Tomlinson, T.P.3
  • 48
    • 0023787586 scopus 로고
    • An international standard for low molecular weight heparin
    • Barrowcliffe TW, Curtis AD, Johnson EA, et al. An international standard for low molecular weight heparin. Thromb Haemost 1988; 60: 1-7.
    • (1988) Thromb Haemost , vol.60 , pp. 1-7
    • Barrowcliffe, T.W.1    Curtis, A.D.2    Johnson, E.A.3
  • 49
    • 0000345281 scopus 로고
    • Preliminary report on post-operative treatment with heparin as a preventive of thrombosis
    • Crafoord C. Preliminary report on post-operative treatment with heparin as a preventive of thrombosis. Acta Chir Scand Suppl 1936; 79: 407-413.
    • (1936) Acta Chir Scand Suppl , vol.79 , pp. 407-413
    • Crafoord, C.1
  • 50
    • 0000261938 scopus 로고
    • Heparin as a prophylaxis against thrombosis
    • Crafoord C, Jorpes J. Heparin as a prophylaxis against thrombosis. J Am Med Assoc 1941; 111: 2831-2840.
    • (1941) J Am Med Assoc , vol.111 , pp. 2831-2840
    • Crafoord, C.1    Jorpes, J.2
  • 51
    • 50549183274 scopus 로고
    • Anticoagulant drugs in the treatment of pulmonary embolism: A controlled trial
    • Barritt D, Jordan S. Anticoagulant drugs in the treatment of pulmonary embolism: a controlled trial. Lancet 1960; 1: 1309-1312.
    • (1960) Lancet , vol.1 , pp. 1309-1312
    • Barritt, D.1    Jordan, S.2
  • 52
    • 0015509824 scopus 로고
    • Efficacy of low doses of heparin in prevention of deep-vein thrombosis after major surgery. A double-blind, randomised trial.
    • Kakkar VV, Corrigan T, Spindler J, et al. Efficacy of low doses of heparin in prevention of deep-vein thrombosis after major surgery. A double-blind, randomised trial. . Lancet 1972; 2: 101-106.
    • (1972) Lancet , vol.2 , pp. 101-106
    • Kakkar, V.V.1    Corrigan, T.2    Spindler, J.3
  • 53
    • 0023886431 scopus 로고
    • Reductions in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic and urological surgery
    • Collins R, Scrimgeour A, Yusef S, et al. Reductions in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic and urological surgery. N Engl J Med 1988; 318: 1162-1173.
    • (1988) N Engl J Med , vol.318 , pp. 1162-1173
    • Collins, R.1    Scrimgeour, A.2    Yusef, S.3
  • 54
    • 0020068331 scopus 로고
    • Low-molecular-weight heparin and prevention of postoperative deep vein thrombosis
    • Kakkar VV, Djazaeri B, Fok J, et al. Low-molecular-weight heparin and prevention of postoperative deep vein thrombosis. Brit Med J 1982; 284: 375-379.
    • (1982) Brit Med J , vol.284 , pp. 375-379
    • Kakkar, V.V.1    Djazaeri, B.2    Fok, J.3
  • 55
    • 0022341051 scopus 로고
    • Efficacy and safety of low-molecular-weight- heparin (CY216) in preventing postoperative venous thrombo-embolism: A co-operative study
    • Kakkar VV, Murray WJG. Efficacy and safety of low-molecular-weight- heparin (CY216) in preventing postoperative venous thrombo-embolism: a co-operative study. Brit J Surg 1985; 72: 786-791.
    • (1985) Brit J Surg , vol.72 , pp. 786-791
    • Kakkar, V.V.1    Murray, W.J.G.2
  • 56
    • 0021241666 scopus 로고
    • Clinical efficacy of low molecular weight heparin in postoperative thrombosis prophylaxis
    • Schmitz-Huebner U, Bunte H, Freise G, et al. Clinical efficacy of low molecular weight heparin in postoperative thrombosis prophylaxis. Klin Woch 1984; 62: 349-353.
    • (1984) Klin Woch , vol.62 , pp. 349-353
    • Schmitz-Huebner, U.1    Bunte, H.2    Freise, G.3
  • 57
    • 0022965499 scopus 로고
    • Low molecular weight heparin (KABI 2165) as thromboprophylaxis in elective visceral surgery. A randomized double-blind study versus unfractionated heparin
    • Koller M Schoch U, Buchmann P, et al. Low molecular weight heparin (KABI 2165) as thromboprophylaxis in elective visceral surgery. A randomized double-blind study versus unfractionated heparin. Thromb Haemost 1986; 56: 243-246.
    • (1986) Thromb Haemost , vol.56 , pp. 243-246
    • Koller, M.1    Schoch, U.2    Buchmann, P.3
  • 58
    • 0022510522 scopus 로고
    • Low molecular weight heparin once daily compared with conventional low-dose heparin twice daily. A prospective double-blind multicentre trial on prevention of postoperative thrombosis
    • Bergvist D, Burmark US, Frisell J, et al. Low molecular weight heparin once daily compared with conventional low-dose heparin twice daily. A prospective double-blind multicentre trial on prevention of postoperative thrombosis. Brit J Surg 1986; 73: 2004-208.
    • (1986) Brit J Surg , vol.73 , pp. 2004-2208
    • Bergvist, D.1    Burmark, U.S.2    Frisell, J.3
  • 59
    • 0023734137 scopus 로고
    • Low molecular weight heparin given the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis
    • Bergvist D Mätzsch T, Burmark US, et al. Low molecular weight heparin given the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis. Brit J Surg 1988; 75: 888-891.
    • (1988) Brit J Surg , vol.75 , pp. 888-891
    • Bergvist, D.1    Mätzsch, T.2    Burmark, U.S.3
  • 60
    • 0023883506 scopus 로고    scopus 로고
    • Caen JP (A French Multicenter Trial). A randomized double blind study between low molecular weight heparin (Kabi 2165) and standard heparin in the prevention of deep vein thrombosis in general surgery. Thomb Haemost 1988; 59: 216-220.
    • Caen JP (A French Multicenter Trial). A randomized double blind study between low molecular weight heparin (Kabi 2165) and standard heparin in the prevention of deep vein thrombosis in general surgery. Thomb Haemost 1988; 59: 216-220.
  • 61
    • 0023837274 scopus 로고
    • GENOX multicentric trial. Low molecular weight heparin compared with unfractionated heparin in prevention of postoperative thrombosis
    • Samama M, Bernard P, Bonnardot JP, et al.; GENOX multicentric trial. Low molecular weight heparin compared with unfractionated heparin in prevention of postoperative thrombosis. Brit J Surg 1988; 75: 128-131.
    • (1988) Brit J Surg , vol.75 , pp. 128-131
    • Samama, M.1    Bernard, P.2    Bonnardot, J.P.3
  • 62
    • 0033816612 scopus 로고    scopus 로고
    • Prophylaxis and treatment of deep-vein thrombosis
    • Breddin HK. Prophylaxis and treatment of deep-vein thrombosis. Sem thromb Haemost 2000; 26 (Suppl 1): 47-52.
    • (2000) Sem thromb Haemost , vol.26 , Issue.SUPPL. 1 , pp. 47-52
    • Breddin, H.K.1
  • 63
    • 0022531588 scopus 로고
    • A randomized controlled trials of a lo-molecular-weight heparin (Enoxparin) to prevent deep-vein thrombosis in patients undergoing elective hip surgery
    • Turpie AGG, Levine MN, Hirsh J, et al. A randomized controlled trials of a lo-molecular-weight heparin (Enoxparin) to prevent deep-vein thrombosis in patients undergoing elective hip surgery. N Engl J Med 1986; 315: 925-929.
    • (1986) N Engl J Med , vol.315 , pp. 925-929
    • Turpie, A.G.G.1    Levine, M.N.2    Hirsh, J.3
  • 64
    • 0023696888 scopus 로고
    • Thrombosis prophylaxis with low molecular weight heparin in total hip replacement
    • Eriksson BI, Zachrisson BE, Teger-Nilsson AC, et al. Thrombosis prophylaxis with low molecular weight heparin in total hip replacement. Brit J Surg 1988; 75: 1053-1057.
    • (1988) Brit J Surg , vol.75 , pp. 1053-1057
    • Eriksson, B.I.1    Zachrisson, B.E.2    Teger-Nilsson, A.C.3
  • 65
    • 0023802370 scopus 로고
    • Safety and efficacy of a low molecular weight heparin (Logiparin) versus dextran as prophylaxis against thrombosis after total hip replacement
    • Mätzsch T, Bergqvist D, Fredin H, et al. Safety and efficacy of a low molecular weight heparin (Logiparin) versus dextran as prophylaxis against thrombosis after total hip replacement. Acta Chir Scand Suppl 1988; 543: 80-84.
    • (1988) Acta Chir Scand Suppl , vol.543 , pp. 80-84
    • Mätzsch, T.1    Bergqvist, D.2    Fredin, H.3
  • 66
    • 0024268035 scopus 로고
    • Prevention of postoperative venous thrombosis: A randomized trial comparing unfractionated heparin with low molecular weight heparin in patients undergoing total hip replacement
    • Planes A, Vochelle N, Mazas F, et al. Prevention of postoperative venous thrombosis: a randomized trial comparing unfractionated heparin with low molecular weight heparin in patients undergoing total hip replacement. Thromb Haemost. 1988; 60: 407-410.
    • (1988) Thromb Haemost , vol.60 , pp. 407-410
    • Planes, A.1    Vochelle, N.2    Mazas, F.3
  • 67
    • 0025774245 scopus 로고
    • Prevention of deep vein thrombosis after elective hip surgery. A randomized trial comparing low molecular weight heparin with standard unfractionated heparin
    • Levine MN, Hirsh J, Gent M, et al. Prevention of deep vein thrombosis after elective hip surgery. A randomized trial comparing low molecular weight heparin with standard unfractionated heparin. Ann Intern Med 1991; 114: 545-551.
    • (1991) Ann Intern Med , vol.114 , pp. 545-551
    • Levine, M.N.1    Hirsh, J.2    Gent, M.3
  • 68
    • 0025163643 scopus 로고    scopus 로고
    • Levine MN, Hirsh J. Clinical potential of low molecular weight heparins. In: Bailliere's Clinical Haematology - Antihrombotic Therapy. Ed J Hirsh. Bailliere Tindall 1990; 3: 545-554.
    • Levine MN, Hirsh J. Clinical potential of low molecular weight heparins. In: Bailliere's Clinical Haematology - Antihrombotic Therapy. Ed J Hirsh. Bailliere Tindall 1990; 3: 545-554.
  • 69
    • 0026576068 scopus 로고
    • Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximalvein thrombosis
    • Hull RD, Raskob GE, Pineo GF, et al. Subcutaneous low-molecular-weight heparin compared with continuous intravenous heparin in the treatment of proximalvein thrombosis. N Engl J Med 1992; 326: 975-982.
    • (1992) N Engl J Med , vol.326 , pp. 975-982
    • Hull, R.D.1    Raskob, G.E.2    Pineo, G.F.3
  • 70
    • 0027931443 scopus 로고
    • Comparison of once-daily subcutaneous Fragmin with continuous intravenous unfractionated heparin in the treatment of deep vein thrombosis
    • Lindmarker P, Holmström M, Granqvist S, et al. Comparison of once-daily subcutaneous Fragmin with continuous intravenous unfractionated heparin in the treatment of deep vein thrombosis. Thromb Haemost 1994; 72: 186-190.
    • (1994) Thromb Haemost , vol.72 , pp. 186-190
    • Lindmarker, P.1    Holmström, M.2    Granqvist, S.3
  • 71
    • 0006590545 scopus 로고    scopus 로고
    • A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis
    • Levine M, Gent M, Hirsh J, et al. A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis. N Engl J Med 1996; 334: 677-681.
    • (1996) N Engl J Med , vol.334 , pp. 677-681
    • Levine, M.1    Gent, M.2    Hirsh, J.3
  • 72
    • 0033816299 scopus 로고    scopus 로고
    • Low-molecular-weight heparins in the treatment of venous thromboembolism
    • Hull RD, Pineo GF. Low-molecular-weight heparins in the treatment of venous thromboembolism. Sem Thromb Haemost 2000; 26 (Suppl 1): 61-67.
    • (2000) Sem Thromb Haemost , vol.26 , Issue.SUPPL. 1 , pp. 61-67
    • Hull, R.D.1    Pineo, G.F.2
  • 74
    • 0026718529 scopus 로고
    • Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: A meta-analysis
    • Nurmohamed MT, Rosendaal FR, Büller HR, et al. Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis. Lancet 1992; 340: 152-156.
    • (1992) Lancet , vol.340 , pp. 152-156
    • Nurmohamed, M.T.1    Rosendaal, F.R.2    Büller, H.R.3
  • 75
    • 0027932867 scopus 로고
    • Comparison of efficacy and safety of low molecular weight heparins and unfractionated heparin in initial treatment of deep venous thrombosis: A meta-analysis
    • Leizorovicz A, Simonneau G, Decousus H, et al. Comparison of efficacy and safety of low molecular weight heparins and unfractionated heparin in initial treatment of deep venous thrombosis: a meta-analysis. Br Med J 1994; 309: 299-304.
    • (1994) Br Med J , vol.309 , pp. 299-304
    • Leizorovicz, A.1    Simonneau, G.2    Decousus, H.3
  • 76
    • 0029145909 scopus 로고
    • Low molecular weight heparins (LMWH) in the treatment of patients with acute venous thromboembolism
    • Hirsh J, Siragusa S, Cosmi B, et al. Low molecular weight heparins (LMWH) in the treatment of patients with acute venous thromboembolism. Thromb Haemost 1995; 74: 360-363.
    • (1995) Thromb Haemost , vol.74 , pp. 360-363
    • Hirsh, J.1    Siragusa, S.2    Cosmi, B.3
  • 77
    • 0031013428 scopus 로고    scopus 로고
    • Efficacy and safety of a low-molecular-weight heparin and standard unfractionated heparin for prophylaxis of postoperative venous thromboembolism: European multicenter trial
    • Kakkar VV, Boeckl O, Boneu B, et al. Efficacy and safety of a low-molecular-weight heparin and standard unfractionated heparin for prophylaxis of postoperative venous thromboembolism: European multicenter trial. World J Surg 1997; 21: 2-8.
    • (1997) World J Surg , vol.21 , pp. 2-8
    • Kakkar, V.V.1    Boeckl, O.2    Boneu, B.3
  • 78
    • 0025355310 scopus 로고
    • Prophylaxis of thromboembolism in general surgery: Comparison between standard heparin and Fragmin
    • Hartl P, Brücke P, Dienstl E, et al. Prophylaxis of thromboembolism in general surgery: comparison between standard heparin and Fragmin. Thromb Res 1990; 57: 577-584.
    • (1990) Thromb Res , vol.57 , pp. 577-584
    • Hartl, P.1    Brücke, P.2    Dienstl, E.3
  • 79
    • 1842369696 scopus 로고    scopus 로고
    • Low-molecular-weight heparin in the treatment of patients with venous thromboembolism
    • The Columbus Investigators
    • The Columbus Investigators. Low-molecular-weight heparin in the treatment of patients with venous thromboembolism. N Engl J Med 1997; 337: 657-662.
    • (1997) N Engl J Med , vol.337 , pp. 657-662
  • 80
    • 42249086288 scopus 로고    scopus 로고
    • Treatment of pulmonary embolism: The use of low-molecular-weight heparin in the inpatient and outpatient settings
    • Hull RD. Treatment of pulmonary embolism: The use of low-molecular-weight heparin in the inpatient and outpatient settings. Thromb Haemost 2008; 99: 502-510.
    • (2008) Thromb Haemost , vol.99 , pp. 502-510
    • Hull, R.D.1
  • 81
    • 0027525087 scopus 로고
    • Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina
    • Théroux P, Waters D, Qiu S, et al. Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina. Circulation 1993; 88: 2045-2048.
    • (1993) Circulation , vol.88 , pp. 2045-2048
    • Théroux, P.1    Waters, D.2    Qiu, S.3
  • 82
    • 0028082271 scopus 로고
    • Combination antithrombotic therapy in unstable rest angina and non-Q-wave infarction in nonprior aspirin users. Primary end points analysis from the ATACS trial. Antithrombotic Therapy in Acute Coronary Syndromes Research Group
    • Cohen M, Adams PC, Parry G, et al. Combination antithrombotic therapy in unstable rest angina and non-Q-wave infarction in nonprior aspirin users. Primary end points analysis from the ATACS trial. Antithrombotic Therapy in Acute Coronary Syndromes Research Group. Circulation 1994; 89: 81-88.
    • (1994) Circulation , vol.89 , pp. 81-88
    • Cohen, M.1    Adams, P.C.2    Parry, G.3
  • 83
    • 0029100793 scopus 로고
    • Low molecular weight heparin versus regular heparin or aspirin in the treatment of unstable angina and silent ischemia
    • Gurfinkel EP, Manos EJ, Mejaíl RI, et al. Low molecular weight heparin versus regular heparin or aspirin in the treatment of unstable angina and silent ischemia. J Am Coll Cardiol 1995; 26: 313-318.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 313-318
    • Gurfinkel, E.P.1    Manos, E.J.2    Mejaíl, R.I.3
  • 84
    • 0032742229 scopus 로고    scopus 로고
    • The FRAX.I.S. Study Group. Comparison of two treatment durations (6 days and 14 days) of a low molecular weight heparin with a 6-day treatment of unfractionated heparin in the initial management of unstable angina or non-Q wave myocardial infarction: FRAX.I.S. (FRAxiparine in Ischaemic Syndrome). Eur Heart J 1999; 20: 1553-1562.
    • The FRAX.I.S. Study Group. Comparison of two treatment durations (6 days and 14 days) of a low molecular weight heparin with a 6-day treatment of unfractionated heparin in the initial management of unstable angina or non-Q wave myocardial infarction: FRAX.I.S. (FRAxiparine in Ischaemic Syndrome). Eur Heart J 1999; 20: 1553-1562.
  • 85
    • 0034667832 scopus 로고    scopus 로고
    • The role of low-molecular-weight heparin in arterial diseases: Optimizing antithrombotic therapy
    • Cohen M. The role of low-molecular-weight heparin in arterial diseases: optimizing antithrombotic therapy. Thromb Res 2000; 100: 131-139.
    • (2000) Thromb Res , vol.100 , pp. 131-139
    • Cohen, M.1
  • 86
    • 8544279582 scopus 로고    scopus 로고
    • A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease
    • for the Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group
    • Cohen M, Demers C, Gurfinkel EP, et al., for the Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group. A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. N Engl J Med 1997; 337: 447-452.
    • (1997) N Engl J Med , vol.337 , pp. 447-452
    • Cohen, M.1    Demers, C.2    Gurfinkel, E.P.3
  • 87
    • 0032870952 scopus 로고    scopus 로고
    • Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q-wave myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) 11B trial
    • Antman EM, McCabe CH, Gurfinkel EP, et al. Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q-wave myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) 11B trial. Circulation 1999; 100: 1593-1601.
    • (1999) Circulation , vol.100 , pp. 1593-1601
    • Antman, E.M.1    McCabe, C.H.2    Gurfinkel, E.P.3
  • 88
    • 38349106680 scopus 로고    scopus 로고
    • Efficacy and safety of enoxaparin in unselected patients with STsegment elevation myocardial infarction
    • Zeymer U, Gitt A, Jünger C, et al. Efficacy and safety of enoxaparin in unselected patients with STsegment elevation myocardial infarction. Thromb Haemost 2008; 99: 150-154.
    • (2008) Thromb Haemost , vol.99 , pp. 150-154
    • Zeymer, U.1    Gitt, A.2    Jünger, C.3
  • 89
    • 0033821369 scopus 로고    scopus 로고
    • Antithrombotics and anticoagulants in coronary syndromes
    • Turpie AGG. Antithrombotics and anticoagulants in coronary syndromes. Sem Thromb Haemost 2000; 26 (Suppl 1): 79-83.
    • (2000) Sem Thromb Haemost , vol.26 , Issue.SUPPL. 1 , pp. 79-83
    • Turpie, A.G.G.1
  • 91
    • 0029925784 scopus 로고    scopus 로고
    • Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: Results of a meta-analysis
    • Siragusa S, Cosmi B, Piovella F, et al. Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: results of a meta-analysis. Am J Med 1996; 100: 269-277.
    • (1996) Am J Med , vol.100 , pp. 269-277
    • Siragusa, S.1    Cosmi, B.2    Piovella, F.3
  • 92
    • 0028939906 scopus 로고
    • Treatment of deep venous thrombosis with low-molecular-weight heparins. A meta-analysis
    • Lensing AW, Prins MH, Davidson BL, et al. Treatment of deep venous thrombosis with low-molecular-weight heparins. A meta-analysis. Arch Intern Med 1995; 155: 601-607.
    • (1995) Arch Intern Med , vol.155 , pp. 601-607
    • Lensing, A.W.1    Prins, M.H.2    Davidson, B.L.3
  • 93
    • 0037067889 scopus 로고    scopus 로고
    • Comparison of low-molecular-weight heparin and warfarin for the secondary prevention of venous thromboembolism in patients with cancer: A randomized controlled study
    • Meyer G, Marjanovic Z, Valcke J, et al. Comparison of low-molecular-weight heparin and warfarin for the secondary prevention of venous thromboembolism in patients with cancer: a randomized controlled study. Arch Intern Med 2002; 162: 1729-1735.
    • (2002) Arch Intern Med , vol.162 , pp. 1729-1735
    • Meyer, G.1    Marjanovic, Z.2    Valcke, J.3
  • 94
    • 0037775584 scopus 로고    scopus 로고
    • Randomized Comparison of Low-Molecular-Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer (CLOT) Investigators. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer
    • Lee AY, Levine MN, Baker RI, et al.; Randomized Comparison of Low-Molecular-Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer (CLOT) Investigators. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med 2003; 349: 146-153.
    • (2003) N Engl J Med , vol.349 , pp. 146-153
    • Lee, A.Y.1    Levine, M.N.2    Baker, R.I.3
  • 95
    • 13244260740 scopus 로고    scopus 로고
    • Fixed-dose low-molecular-weight heparin for secondary prevention of venous thromboembolism in patients with disseminated cancer: A prospective cohort study
    • Monreal M, Zacharski L, Jiménez JA, et al. Fixed-dose low-molecular-weight heparin for secondary prevention of venous thromboembolism in patients with disseminated cancer: a prospective cohort study. J Thromb Haemost 2004; 2: 1311-1315.
    • (2004) J Thromb Haemost , vol.2 , pp. 1311-1315
    • Monreal, M.1    Zacharski, L.2    Jiménez, J.A.3
  • 96
    • 34548169044 scopus 로고    scopus 로고
    • A meta-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: Impact on survival and bleeding complication
    • Kuderer NM, Khorana AA, Lyman H, et al. A meta-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: impact on survival and bleeding complication. Cancer 2007; 110: 1149-1161.
    • (2007) Cancer , vol.110 , pp. 1149-1161
    • Kuderer, N.M.1    Khorana, A.A.2    Lyman, H.3
  • 97
    • 38649098255 scopus 로고    scopus 로고
    • Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation
    • CD006652
    • Akl EA, van Doormaal FF, Barba M, et al. Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation. Cochrane Database Syst Rev 2007; 18: CD006652.
    • (2007) Cochrane Database Syst Rev , vol.18
    • Akl, E.A.1    van Doormaal, F.F.2    Barba, M.3
  • 98
    • 34248525326 scopus 로고    scopus 로고
    • The effect of anticoagulants on cancer risk and survival: Systematic review
    • Tagalakis V, Blostein M, Robinson-Cohen C, et al. The effect of anticoagulants on cancer risk and survival: systematic review. Cancer Treat Rev 2007; 33: 358-368.
    • (2007) Cancer Treat Rev , vol.33 , pp. 358-368
    • Tagalakis, V.1    Blostein, M.2    Robinson-Cohen, C.3
  • 99
    • 34248369423 scopus 로고    scopus 로고
    • Venous thromboembolism prevention in gynaecologic cancer surgery: A systematic review
    • Einstein MH, Fritts EA, Hartenbach EM. Venous thromboembolism prevention in gynaecologic cancer surgery: a systematic review. Gynecol Oncol 2007; 105: 813-819.
    • (2007) Gynecol Oncol , vol.105 , pp. 813-819
    • Einstein, M.H.1    Fritts, E.A.2    Hartenbach, E.M.3
  • 100
    • 34548650250 scopus 로고    scopus 로고
    • Low molecular weight heparin in cancer associated thrombosis: Treatment, secondary prevention, and survival
    • Nishioka J, Goodin S. Low molecular weight heparin in cancer associated thrombosis: treatment, secondary prevention, and survival. J Oncol Pharm Pract 2007; 13: 85-97.
    • (2007) J Oncol Pharm Pract , vol.13 , pp. 85-97
    • Nishioka, J.1    Goodin, S.2
  • 101
    • 34147166702 scopus 로고    scopus 로고
    • The effect of low-molecular-weight heparin on cancer survival. A systematic review and meta-analysis of randomized trials
    • Lazo-Langner A, Goss GD, Spaans JN, et al. The effect of low-molecular-weight heparin on cancer survival. A systematic review and meta-analysis of randomized trials. J Thromb Haemost 2007; 5: 729-737.
    • (2007) J Thromb Haemost , vol.5 , pp. 729-737
    • Lazo-Langner, A.1    Goss, G.D.2    Spaans, J.N.3
  • 102
    • 43949108178 scopus 로고    scopus 로고
    • Comparison of low-molecular-weight heparin and antithrombin versus antithrombin alone for the prevention of symptomatic venous thromboembolism in children with acute lymphoblastic leukemia
    • Epub ahead of print
    • Meister B, Kropshofer G, Klein-Franke A, et al. Comparison of low-molecular-weight heparin and antithrombin versus antithrombin alone for the prevention of symptomatic venous thromboembolism in children with acute lymphoblastic leukemia. Pediatr Blood Cancer 2007; Epub ahead of print.
    • (2007) Pediatr Blood Cancer
    • Meister, B.1    Kropshofer, G.2    Klein-Franke, A.3
  • 103
    • 34248202262 scopus 로고    scopus 로고
    • Low molecular weight heparin (LMWH) increases the efficacy of cis-platinum plus gemcitabine combination in advanced pancreatic cancer
    • Icli F, Akbulut H, Utkan G, et al. Low molecular weight heparin (LMWH) increases the efficacy of cis-platinum plus gemcitabine combination in advanced pancreatic cancer. J Surg Oncol 2007; 95: 507-512.
    • (2007) J Surg Oncol , vol.95 , pp. 507-512
    • Icli, F.1    Akbulut, H.2    Utkan, G.3
  • 104
    • 0027983848 scopus 로고
    • Low molecular weight heparin therapy: Is monitoring needed?
    • Boneu B. Low molecular weight heparin therapy: is monitoring needed? Thromb Haemost 1994; 72: 330-334.
    • (1994) Thromb Haemost , vol.72 , pp. 330-334
    • Boneu, B.1
  • 105
    • 0031680310 scopus 로고    scopus 로고
    • Laposata M, Green D, Van Cott ENM, et al. College of American Pathologists Conference XXXI on Laboratory Monitoring of Anticoagulant Therapy. The clinical use and laboratory monitoring of low-molecular-weight heparin, danaparoid, hirudin and related compounds, and argatroban. Arch Pathol Lab Med 1998; 122: 799-807.
    • Laposata M, Green D, Van Cott ENM, et al. College of American Pathologists Conference XXXI on Laboratory Monitoring of Anticoagulant Therapy. The clinical use and laboratory monitoring of low-molecular-weight heparin, danaparoid, hirudin and related compounds, and argatroban. Arch Pathol Lab Med 1998; 122: 799-807.
  • 106
    • 3242734130 scopus 로고    scopus 로고
    • Is laboratory monitoring of low-molecular-weight heparin therapy necessary? Yes
    • Harenberg J. Is laboratory monitoring of low-molecular-weight heparin therapy necessary? Yes. J Thromb Haemost 2004; 2: 547-550.
    • (2004) J Thromb Haemost , vol.2 , pp. 547-550
    • Harenberg, J.1
  • 107
    • 3242678141 scopus 로고    scopus 로고
    • Is laboratory monitoring of low-molecular-weight heparin therapy necessary?
    • Bounameaux H, De Moerloose P. Is laboratory monitoring of low-molecular-weight heparin therapy necessary? No. J Thromb Haemost 2004; 2: 551-554.
    • (2004) J Thromb Haemost , vol.2 , pp. 551-554
    • Bounameaux, H.1    De Moerloose, P.2
  • 108
    • 13244259367 scopus 로고    scopus 로고
    • Laboratory monitoring of low-molecular-weight heparin therapy
    • Hirsh J. Laboratory monitoring of low-molecular-weight heparin therapy. J Thromb Haemost 2004; 2: 1003-1003.
    • (2004) J Thromb Haemost , vol.2 , pp. 1003-1003
    • Hirsh, J.1
  • 109
    • 23944434544 scopus 로고    scopus 로고
    • Laboratory monitoring of low-molecular-weight heparin therapy - part II
    • Boneu B. Laboratory monitoring of low-molecular-weight heparin therapy - part II. J Thromb Haemost 2005; 3: 573-574.
    • (2005) J Thromb Haemost , vol.3 , pp. 573-574
    • Boneu, B.1
  • 110
    • 0023135234 scopus 로고
    • The effect of low molecular weight heparin on experimental thrombosis and haemostasis -the influence of production method
    • Ostergaard PB, Nilsson B, Bergqvist D, et al. The effect of low molecular weight heparin on experimental thrombosis and haemostasis -the influence of production method. Thromb Res 1987; 45: 739-749.
    • (1987) Thromb Res , vol.45 , pp. 739-749
    • Ostergaard, P.B.1    Nilsson, B.2    Bergqvist, D.3
  • 111
    • 0034667833 scopus 로고    scopus 로고
    • For the initial treatment of venous thromboembolism: Are all low-molecular -weight heparin compounds the same?
    • van der Heijden JF, Prins MH, Büller HR. For the initial treatment of venous thromboembolism: are all low-molecular -weight heparin compounds the same? Thromb Res 2000; 100: 121-130.
    • (2000) Thromb Res , vol.100 , pp. 121-130
    • van der Heijden, J.F.1    Prins, M.H.2    Büller, H.R.3
  • 112
    • 0141818981 scopus 로고    scopus 로고
    • Low molecular weight heparins: Are they interchangeable? Yes
    • Prandoni P. Low molecular weight heparins: are they interchangeable? Yes. J Thromb Haemost 2003; 1: 10-11.
    • (2003) J Thromb Haemost , vol.1 , pp. 10-11
    • Prandoni, P.1
  • 113
    • 0141818975 scopus 로고    scopus 로고
    • Low molecular weight heparins: Are they interchangeable?
    • Nenci GG. Low molecular weight heparins: are they interchangeable? No. J Thromb Haemost 2003; 1: 12-13.
    • (2003) J Thromb Haemost , vol.1 , pp. 12-13
    • Nenci, G.G.1
  • 114
    • 0032750367 scopus 로고    scopus 로고
    • Low molecular weight heparins in the management of unstable angina/non-Q-wave myocardial infarction
    • Cohen M. Low molecular weight heparins in the management of unstable angina/non-Q-wave myocardial infarction. Semin Thromb Haemost 1999; 25 (Suppl 3): 111-119.
    • (1999) Semin Thromb Haemost , vol.25 , Issue.SUPPL. 3 , pp. 111-119
    • Cohen, M.1
  • 115
    • 0033821253 scopus 로고    scopus 로고
    • An equivalence study of two low-molecular-weight heparins in the prevention and treatment of deep-vein thrombosis after total hip replacement
    • Planès A. An equivalence study of two low-molecular-weight heparins in the prevention and treatment of deep-vein thrombosis after total hip replacement. Semin Thromb Hemost 2000; 26 (Suppl 1): 57-60.
    • (2000) Semin Thromb Hemost , vol.26 , Issue.SUPPL. 1 , pp. 57-60
    • Planès, A.1
  • 116
    • 0027737982 scopus 로고
    • Comparison of antithrombotic efficacy and haemorrhagic side-effects of Clivarin versus enoxaparin in patients undergoing total hip replacement surgery
    • Planes A. Comparison of antithrombotic efficacy and haemorrhagic side-effects of Clivarin versus enoxaparin in patients undergoing total hip replacement surgery. Blood Coagul Fibrinolysis 1993; 4 (Suppl 1): S33-35.
    • (1993) Blood Coagul Fibrinolysis , vol.4 , Issue.SUPPL. 1
    • Planes, A.1
  • 117
    • 0031768703 scopus 로고    scopus 로고
    • Comparison of two low-molecular-weight heparins for the prevention of postoperative venous thromboembolism after elective hip surgery. Reviparin Study Group
    • Planès A, Vochelle N, Fagola M, et al. Comparison of two low-molecular-weight heparins for the prevention of postoperative venous thromboembolism after elective hip surgery. Reviparin Study Group. Blood Coag Fibrinolysis 1998; 9: 499-505.
    • (1998) Blood Coag Fibrinolysis , vol.9 , pp. 499-505
    • Planès, A.1    Vochelle, N.2    Fagola, M.3
  • 118
    • 0141823421 scopus 로고    scopus 로고
    • Bemiparin Study Group in Knee Arthroplasty. Efficacy and safety of bemiparin compared with enoxaparin in the prevention of venous thromboembolism after total knee arthroplasty: A randomized, double-blind clinical trial
    • Navarro-Quilis A, Castellet E, Rocha E, et al.; Bemiparin Study Group in Knee Arthroplasty. Efficacy and safety of bemiparin compared with enoxaparin in the prevention of venous thromboembolism after total knee arthroplasty: a randomized, double-blind clinical trial. J Thromb Haemost 2003; 1: 425-432.
    • (2003) J Thromb Haemost , vol.1 , pp. 425-432
    • Navarro-Quilis, A.1    Castellet, E.2    Rocha, E.3
  • 119
    • 33746653728 scopus 로고    scopus 로고
    • FX140 Study Investigators. A randomized study comparing the efficacy and safety of nadroparin 2850 IU (0.3 mL) vs. enoxaparin 4000 IU (40 mg) in the prevention of venous thromboembolism after colorectal surgery for cancer
    • Simonneau G, Laporte S, Mismetti P, et al.; FX140 Study Investigators. A randomized study comparing the efficacy and safety of nadroparin 2850 IU (0.3 mL) vs. enoxaparin 4000 IU (40 mg) in the prevention of venous thromboembolism after colorectal surgery for cancer. J Thromb Haemost 2006; 4: 1693-1700.
    • (2006) J Thromb Haemost , vol.4 , pp. 1693-1700
    • Simonneau, G.1    Laporte, S.2    Mismetti, P.3
  • 120
    • 0037048227 scopus 로고    scopus 로고
    • Fondaparinux vs enoxaparin for the prevention of venous thromboembolism in major orthopedic surgery: A meta-analysis of 4 randomized double-blind studies
    • Turpie AG, Bauer KA, Eriksson BI, et al. Fondaparinux vs enoxaparin for the prevention of venous thromboembolism in major orthopedic surgery: a meta-analysis of 4 randomized double-blind studies. Arch Intern Med 2002; 162: 1833-1840.
    • (2002) Arch Intern Med , vol.162 , pp. 1833-1840
    • Turpie, A.G.1    Bauer, K.A.2    Eriksson, B.I.3
  • 121
    • 2542424669 scopus 로고    scopus 로고
    • Matisse Investigators. Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: A randomized trial
    • Büller HR, Davidson BL, Decousus H, et al.; Matisse Investigators. Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: a randomized trial. Ann Intern Med 2004; 140: 867-873.
    • (2004) Ann Intern Med , vol.140 , pp. 867-873
    • Büller, H.R.1    Davidson, B.L.2    Decousus, H.3
  • 122
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995; 332: 1330-1335.
    • (1995) N Engl J Med , vol.332 , pp. 1330-1335
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3
  • 123
    • 34249804158 scopus 로고    scopus 로고
    • Fondaparinux as a treatment option for heparin-induced thrombocytopenia
    • Papadopoulos S, Flynn JD, Lewis DA. Fondaparinux as a treatment option for heparin-induced thrombocytopenia. Pharmacotherapy 2007; 27: 921-926.
    • (2007) Pharmacotherapy , vol.27 , pp. 921-926
    • Papadopoulos, S.1    Flynn, J.D.2    Lewis, D.A.3
  • 124
    • 38349160990 scopus 로고    scopus 로고
    • Fondaparinux for the treatment of patients with acute heparin-induced thrombocytopenia
    • Lobo B, Finch C, Howard A, et al. Fondaparinux for the treatment of patients with acute heparin-induced thrombocytopenia. Thromb Haemost 2008; 99: 208-214.
    • (2008) Thromb Haemost , vol.99 , pp. 208-214
    • Lobo, B.1    Finch, C.2    Howard, A.3
  • 125
    • 34250749333 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia associated with fondaparinux
    • Warkentin TE, Maurer BT, Aster RH. Heparin-induced thrombocytopenia associated with fondaparinux. N Engl J Med 2007; 356: 2653-2655.
    • (2007) N Engl J Med , vol.356 , pp. 2653-2655
    • Warkentin, T.E.1    Maurer, B.T.2    Aster, R.H.3
  • 126
  • 127
    • 21244492313 scopus 로고    scopus 로고
    • Low molecular weight heparin-induced skin necrosis-a systematic review
    • Handschin AE, Trentz O, Kock HJ, et al. Low molecular weight heparin-induced skin necrosis-a systematic review. Langenbecks Arch Surg 2005; 390: 249-254.
    • (2005) Langenbecks Arch Surg , vol.390 , pp. 249-254
    • Handschin, A.E.1    Trentz, O.2    Kock, H.J.3
  • 128
    • 13444291100 scopus 로고    scopus 로고
    • Tolerance to intravenous heparin in patients with delayed-type hypersensitivity to heparins: A prospective study
    • Gaigl Z, Pfeuffer P, Raith P, et al. Tolerance to intravenous heparin in patients with delayed-type hypersensitivity to heparins: a prospective study. Br J Haematol 2005; 128: 389-392.
    • (2005) Br J Haematol , vol.128 , pp. 389-392
    • Gaigl, Z.1    Pfeuffer, P.2    Raith, P.3
  • 129
    • 36949036472 scopus 로고    scopus 로고
    • Fondaparinux as an alternative therapy in heparin-induced delayed-type hypersensitivity skin lesions
    • O'Meara AC, Demarmels Biasiutti F, Heizmann M. Fondaparinux as an alternative therapy in heparin-induced delayed-type hypersensitivity skin lesions. Thromb Haemost 2007; 98: 1389-1391.
    • (2007) Thromb Haemost , vol.98 , pp. 1389-1391
    • O'Meara, A.C.1    Demarmels Biasiutti, F.2    Heizmann, M.3
  • 130
    • 0030954285 scopus 로고    scopus 로고
    • A histomorphometric comparison of the effects of heparin and low-molecular-weight heparin on cancellous bone in rats
    • Muir JM, Hirsh J, Weitz JI, et al. A histomorphometric comparison of the effects of heparin and low-molecular-weight heparin on cancellous bone in rats. Blood 1997; 89: 3236-3242.
    • (1997) Blood , vol.89 , pp. 3236-3242
    • Muir, J.M.1    Hirsh, J.2    Weitz, J.I.3
  • 131
    • 0025374187 scopus 로고
    • Effects of low molecular weight heparin and unfragmented heparin on induction of osteoporosis in rats
    • Mätzsch T, Bergqvist D, Hedner U, et al. Effects of low molecular weight heparin and unfragmented heparin on induction of osteoporosis in rats. Thromb Haemost 1990; 63: 505-509.
    • (1990) Thromb Haemost , vol.63 , pp. 505-509
    • Mätzsch, T.1    Bergqvist, D.2    Hedner, U.3
  • 132
    • 0024995517 scopus 로고
    • Heparin-related osteoporosis in rats. A comparative study between unfractioned heparin and a low-molecular-weight heparin
    • Monreal M, Viñas L, Monreal L, et al. Heparin-related osteoporosis in rats. A comparative study between unfractioned heparin and a low-molecular-weight heparin. Haemostasis 1990; 20: 204-207.
    • (1990) Haemostasis , vol.20 , pp. 204-207
    • Monreal, M.1    Viñas, L.2    Monreal, L.3
  • 133
    • 0028121058 scopus 로고
    • Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin
    • Monreal M, Lafoz E, Olive A, et al. Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin. Thromb Haemost 1994; 71: 7-11.
    • (1994) Thromb Haemost , vol.71 , pp. 7-11
    • Monreal, M.1    Lafoz, E.2    Olive, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.