Extracellular hemoglobin polarizes the macrophage proteome toward Hb-clearance, enhanced antioxidant capacity and suppressed HLA class 2 expression

Journal of Proteome Research

Volumn 10, Issue 5, 2011, Pages 2397-2408

  Kaempfer, Theresa ^a   Duerst, Elena ^a   Gehrig, Peter ^b   Roschitzki, Bernd ^b   Rutishauser, Dorothea ^b   Grossmann, Jonas ^b   Schoedon, Gabriele ^a   Vallelian, Florence ^c   Schaer, Dominik J ^a,c  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

haptoglobin; hemoglobin; HLA class 2; macrophage; monocyte; oxidative Stress; proteomics

Indexed keywords

CD163 ANTIGEN; FERRITIN; HEMOGLOBIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEOME; SCAVENGER RECEPTOR;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROTIC PLAQUE; BLEEDING; CELL POLARITY; CELL POPULATION; CLEARANCE; CONTROLLED STUDY; DETOXIFICATION; HOMEOSTASIS; HUMAN; HUMAN CELL; MACROPHAGE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TISSUE INJURY; WOUND HEALING;

ANALYSIS OF VARIANCE; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL DIFFERENTIATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENES, MHC CLASS II; HAPTOGLOBINS; HEMOGLOBINS; MACROPHAGES; MASS SPECTROMETRY; PROTEOME; PROTEOMICS; RECEPTORS, CELL SURFACE; RECEPTORS, SCAVENGER;

EID: 79955809197     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr101230y     Document Type: Article

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