-
1
-
-
0031682988
-
The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
-
Honkakoski P, Zelko I, Sueyoshi T and Negishi M: The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital- responsive enhancer module of the CYP2B gene. Mol Cell Biol 18: 5652-5658, 1998. (Pubitemid 28450516)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.10
, pp. 5652-5658
-
-
Honkakoski, P.1
Zelko, I.2
Sueyoshi, T.3
Negishi, M.4
-
2
-
-
0033525886
-
The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene
-
DOI 10.1074/jbc.274.10.6043
-
Sueyoshi T, Kawamoto T, Zelko I, Honkakoski P and Negishi M: The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6. J Biol Chem 274: 6043-6046, 1999. (Pubitemid 29111006)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.10
, pp. 6043-6046
-
-
Sueyoshi, T.1
Kawamoto, T.2
Zelko, I.3
Honkakoski, P.4
Negishi, M.5
-
3
-
-
0034687397
-
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
-
Wei P, Zhang J, Egan-Hafley M, Liang S and Moore DD: The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 407: 920-923, 2000.
-
(2000)
Nature
, vol.407
, pp. 920-923
-
-
Wei, P.1
Zhang, J.2
Egan-Hafley, M.3
Liang, S.4
Moore, D.D.5
-
5
-
-
33646713469
-
Phenobarbital confers its diverse effects by activating the orphan nuclear receptor CAR
-
DOI 10.1080/03602530600569851, PII U20039367345
-
Kodama S and Negishi M: Phenobarbital confers its diverse effects by activating the orphan nuclear receptor CAR. Drug Metab Rev 38: 75-87, 2006. (Pubitemid 43739000)
-
(2006)
Drug Metabolism Reviews
, vol.38
, Issue.1-2
, pp. 75-87
-
-
Kodama, S.1
Negishi, M.2
-
6
-
-
34247349605
-
Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: Implications for interindividual variability in response to drugs
-
DOI 10.1177/0091270007299930
-
Urquhart BL, Tirona RG and Kim RB: Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for inter-individual variability in response to drugs. J Clin Pharmacol 47: 566-578, 2007. (Pubitemid 46632158)
-
(2007)
Journal of Clinical Pharmacology
, vol.47
, Issue.5
, pp. 566-578
-
-
Urquhart, B.L.1
Tirona, R.G.2
Kim, R.B.3
-
7
-
-
0036142429
-
Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital
-
DOI 10.1124/mol.61.1.1
-
Ueda A, Hamadeh HK, Webb HK, Yamamoto Y, Sueyoshi T, Afshari CA, Lehmann JM and Negishi M: Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital. Mol Pharmacol 61: 1-6, 2002. (Pubitemid 34049505)
-
(2002)
Molecular Pharmacology
, vol.61
, Issue.1
, pp. 1-6
-
-
Ueda, A.1
Hamadeh, H.K.2
Webb, H.K.3
Yamamoto, Y.4
Sueyoshi, T.5
Afshari, C.A.6
Lehmann, J.M.7
Negishi, M.8
-
8
-
-
4444246000
-
Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes
-
DOI 10.1128/MCB.24.18.7931-7940.2004
-
Kodama S, Koike C, Negishi M and Yamamoto Y: Nuclear receptors CAR and PXR cross talk with FoxO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes. Mol Cell Biol 24: 7931-7940, 2004. (Pubitemid 39167443)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.18
, pp. 7931-7940
-
-
Kodama, S.1
Koike, C.2
Negishi, M.3
Yamamoto, Y.4
-
9
-
-
52449108842
-
New insights on the xenobiotic-sensing nuclear receptors in liver diseases -CAR and RXR
-
Kakizaki S, Yamazaki Y, Takizawa D and Negishi M: New insights on the xenobiotic-sensing nuclear receptors in liver diseases -CAR and RXR. Curr Drug Metab 9: 614-621, 2008.
-
(2008)
Curr Drug Metab
, vol.9
, pp. 614-621
-
-
Kakizaki, S.1
Yamazaki, Y.2
Takizawa, D.3
Negishi, M.4
-
11
-
-
0022974904
-
Comparative analysis of the effect of phenobarbital, dichlorodiphenyltrichloroethane, butylated hydroxytoluene and nafenopin on rat hepatocarcinogenesis
-
Preat V, de Gerlache J, Lans M, Taper H and Roberfroid M: Comparative analysis of the effect of phenobarbital, dichlorodiphenyltrichloroethane, butylated hydroxytoluene and nafenopin on rat hepatocarcinogenesis. Carcinogenesis 7: 1025-1028, 1986. (Pubitemid 17130510)
-
(1986)
Carcinogenesis
, vol.7
, Issue.6
, pp. 1025-1028
-
-
Preat, V.1
De Gerlache, J.2
Lans, M.3
-
12
-
-
0026523138
-
The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat
-
Dragon YP and Pitot HC: The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat. Carcinogenesis 13: 739-750, 1992.
-
(1992)
Carcinogenesis
, vol.13
, pp. 739-750
-
-
Dragon, Y.P.1
Pitot, H.C.2
-
13
-
-
5644295430
-
The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice
-
DOI 10.1158/0008-5472.CAN-04-1459
-
Yamamoto Y, Moore R, Goldsworthy TL, Negishi M and Maronpot RR: The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice. Cancer Res 64: 7197-7200, 2004. (Pubitemid 39372050)
-
(2004)
Cancer Research
, vol.64
, Issue.20
, pp. 7197-7200
-
-
Yamamoto, Y.1
Moore, R.2
Goldsworthy, T.L.3
Negishi, M.4
Maronpot, R.R.5
-
14
-
-
39049184076
-
A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells
-
Kobayashi T, Masaki T, Sugiyama M, Atomi Y, Furukawa Y and Nakamura Y: A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. Int J Oncol 29: 341-347, 2006.
-
(2006)
Int J Oncol
, vol.29
, pp. 341-347
-
-
Kobayashi, T.1
Masaki, T.2
Sugiyama, M.3
Atomi, Y.4
Furukawa, Y.5
Nakamura, Y.6
-
15
-
-
44849100002
-
Nuclear receptor CAR requires early growth response 1 to activate the human cytochrome P450 2B6 gene
-
Inoue K and Negishi M: Nuclear receptor CAR requires early growth response 1 to activate the human cytochrome P450 2B6 gene. J Biol Chem 283: 10425-10432, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 10425-10432
-
-
Inoue, K.1
Negishi, M.2
-
16
-
-
0029940554
-
Strain dependent effects of sex hormones on hepatocarcinogenesis in mice
-
DOI 10.1093/carcin/17.2.191
-
Poole TM and Drinkwater NR: Strain dependent effects of sex hormones on hepatocarcinogenesis in mice. Carcinogenesis 17: 191-196, 1996. (Pubitemid 26091293)
-
(1996)
Carcinogenesis
, vol.17
, Issue.2
, pp. 191-196
-
-
Poole, T.M.1
Drinkwater, N.R.2
-
18
-
-
0023015363
-
The histology and development of hepatic nodules in C3H/He mice following chronic administration of phenobarbitone
-
Evans JG, Collins MA, Savage SA, Lake BG and Butler WH: The histology and development of hepatic nodules in C3H/He mice following chronic administration of phenobarbitone. Carcinogenesis 7: 627-631, 1986. (Pubitemid 17130493)
-
(1986)
Carcinogenesis
, vol.7
, Issue.4
, pp. 627-631
-
-
Evans, J.G.1
Collins, M.A.2
Savage, S.A.3
-
19
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
DOI 10.1016/j.biocel.2006.07.001, PII S1357272506002196
-
Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M and Telser J: Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39: 44-84, 2007. (Pubitemid 44566469)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.1
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.D.4
Mazur, M.5
Telser, J.6
-
20
-
-
4444268690
-
Mechanisms that regulate production of reactive oxygen species by cytochrome P450
-
DOI 10.1016/j.taap.2004.01.018, PII S0041008X04001231
-
Zangar RC, Davydov DR and Verma S: Mechanisms that regulate production of reactive oxygen species by cytochrome P450. Toxicol Appl Pharmacol 199: 316-331, 2004. (Pubitemid 39208731)
-
(2004)
Toxicology and Applied Pharmacology
, vol.199
, Issue.3
, pp. 316-331
-
-
Zangar, R.C.1
Davydov, D.R.2
Verma, S.3
-
21
-
-
0036125801
-
WAF/Cip1, cyclin D1 and Ogg1
-
WAF/Cip1, cyclin D1 and Ogg1. Carcinogenesis 23: 341-349, 2002.
-
(2002)
Carcinogenesis
, vol.23
, pp. 341-349
-
-
Kinoshita, A.1
Wanibuchi, H.2
Imaoka, S.3
Ogawa, M.4
Masuda, C.5
Morimura, K.6
Funae, Y.7
Fukushima, S.8
-
22
-
-
0346724935
-
Role of phenobarbital-inducible cytochrome P450s as a source of active oxygen species in DNA-oxidation
-
DOI 10.1016/j.canlet.2003.09.009
-
Imaoka S, Osada M, Minamiyama Y, Yukimura T, Toyokuni S, Takemura S, Hiroi T and Funae Y: Role of phenobarbital-inducible cytochrome P450s as a source of active oxygen species in DNA-oxidation. Cancer Lett 203: 117-125, 2004. (Pubitemid 38058680)
-
(2004)
Cancer Letters
, vol.203
, Issue.2
, pp. 117-125
-
-
Imaoka, S.1
Osada, M.2
Minamiyama, Y.3
Yukimura, T.4
Toyokuni, S.5
Takemura, S.6
Hiroi, T.7
Funae, Y.8
-
23
-
-
57349094259
-
Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability
-
Pebernard S, Perry JJ, Tainer JA and Boddy MN: Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability. Mol Biol Cell 19: 4099-4109, 2008.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4099-4109
-
-
Pebernard, S.1
Perry, J.J.2
Tainer, J.A.3
Boddy, M.N.4
-
24
-
-
3142670509
-
A potent modifier of liver cancer risk on distal mouse chromosome 1: Linkage analysis and characterization of congenic lines
-
DOI 10.1534/genetics.103.024521
-
Bilger A, Bennett LM, Carabeo RA, Chiaverotti TA, Dvorak C, Liss KM, Schadewald SA, Pitot HC and Drinkwater NR: A potent modifier of liver cancer risk on distal mouse chromosome 1: linkage analysis and characterization of congenic lines. Genetics 167: 859-866, 2004. (Pubitemid 38931870)
-
(2004)
Genetics
, vol.167
, Issue.2
, pp. 859-866
-
-
Bilger, A.1
Bennett, L.M.2
Carabeo, R.A.3
Chiaverotti, T.A.4
Dvorak, C.5
Liss, K.M.6
Schadewald, S.A.7
Pitot, H.C.8
Drinkwater, N.R.9
-
25
-
-
20444393130
-
Cytogenetic and molecular genetic alterations in hepatocellular carcinoma
-
Lau SH and Guan XY: Cytogenetic and molecular genetic alterations in hepatocellular carcinoma. Acta Pharmacol Sin 26: 659-665, 2005.
-
(2005)
Acta Pharmacol Sin
, vol.26
, pp. 659-665
-
-
Lau, S.H.1
Guan, X.Y.2
|