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Volumn 3, Issue 2, 2010, Pages 53-59

CFH, VEGF, and PEDF genotypes and the response to intravitreous injection of bevacizumab for the treatment of age-related macular degeneration

Author keywords

Age related macular degeneration; Bevacizumab; Complement factor H; Genetic biomarker; High temperature requirement A 1; Pigment epitheliumderived factor; Vascular endothelial growth factor

Indexed keywords

BEVACIZUMAB; BIOLOGICAL MARKER; COMPLEMENT FACTOR H; HIGH TEMPERATURE REQUIREMENT A1; PIGMENT EPITHELIUM DERIVED FACTOR; SERINE PROTEINASE; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 79955796065     PISSN: 19368437     EISSN: 19368445     Source Type: Journal    
DOI: 10.1007/s12177-010-9055-1     Document Type: Article
Times cited : (40)

References (45)
  • 1
    • 0033652453 scopus 로고    scopus 로고
    • Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-related eye disease study report number 3
    • Age-Related Eye Disease Study Research Group
    • Age-Related Eye Disease Study Research Group. Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: age-related eye disease study report number 3. Ophthalmology. 2000;107:2224-32.
    • (2000) Ophthalmolog , vol.107 , pp. 2224-2232
  • 2
    • 0242526930 scopus 로고    scopus 로고
    • Age-Related Eye Disease Study Research Group. Potential public health impact of age-related eye disease study results. AREDS report no. 11
    • Age-Related Eye Disease Study Research Group. Potential public health impact of age-related eye disease study results. AREDS report no. 11. Arch Ophthalmol. 2003;121:1621-4.
    • (2003) Arch Ophthalmol , vol.121 , pp. 1621-1624
  • 3
    • 16244368037 scopus 로고    scopus 로고
    • Age-Related Eye Disease Study Research Group. Risk factors for the incidence of advanced age-related macular degeneration in the age-related eye disease study. AREDS report no. 19
    • Age-Related Eye Disease Study Research Group. Risk factors for the incidence of advanced age-related macular degeneration in the age-related eye disease study. AREDS report no. 19. Am J Ophthalmol. 2005;112:533-9.
    • (2005) Am J Ophthalmol , vol.112 , pp. 533-539
  • 10
    • 33748309136 scopus 로고    scopus 로고
    • Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
    • DOI 10.1038/ng1873, PII NG1873
    • Maller J, George S, Purcell S, Fagerness J, Altshuler D, Daly MJ, et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet. 2006;38:1055-9. (Pubitemid 44325932)
    • (2006) Nature Genetics , vol.38 , Issue.9 , pp. 1055-1059
    • Maller, J.1    George, S.2    Purcell, S.3    Fagerness, J.4    Altshuler, D.5    Daly, M.J.6    Seddon, J.M.7
  • 12
    • 27744462212 scopus 로고    scopus 로고
    • Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
    • DOI 10.1093/hmg/ddi353
    • Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, Meitinger T, et al. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet. 2005;14:3227-36. (Pubitemid 41631297)
    • (2005) Human Molecular Genetics , vol.14 , Issue.21 , pp. 3227-3236
    • Rivera, A.1    Fisher, S.A.2    Fritsche, L.G.3    Keilhauer, C.N.4    Lichtner, P.5    Meitinger, T.6    Weber, B.H.F.7
  • 13
    • 33646070308 scopus 로고    scopus 로고
    • Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration
    • Schmidt S, Hauser MA, Scott WK, Postel EA, Agarwal A, Gallins P, et al. Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. Am J Hum Genet. 2006;78:852-64.
    • (2006) Am J Hum Genet , vol.78 , pp. 852-864
    • Schmidt, S.1    Hauser, M.A.2    Scott, W.K.3    Postel, E.A.4    Agarwal, A.5    Gallins, P.6
  • 18
    • 0030758411 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and the eye: Biochemical mechanisms of action and implications for novel therapies
    • Aiello LP. Vascular endothelial growth factor and the eye: biochemical mechanisms of action and implications for novel therapies. Ophthalmic Res. 1997;29:354-62. (Pubitemid 27427368)
    • (1997) Ophthalmic Research , vol.29 , Issue.5 , pp. 354-362
    • Aiello, L.P.1
  • 19
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989;246:1306-9. (Pubitemid 20066716)
    • (1989) Science , vol.246 , Issue.4935 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.-J.3    Goeddel, D.V.4    Ferrara, N.5
  • 20
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
    • DOI 10.1126/science.285.5425.245
    • Dawson DW, Volpert OV, Gillis P, Crawford SE, Xu HJ, Benedict W, et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science. 1999;285:245-8. (Pubitemid 29329995)
    • (1999) Science , vol.285 , Issue.5425 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3    Crawford, S.E.4    Xu, H.-J.5    Benedict, W.6    Bouck, N.P.7
  • 21
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid, and other diseases
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid, and other diseases. Nat Med. 1995;1:27-31.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 23
    • 0036329579 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration
    • DOI 10.1016/S0002-9394(02)01549-0, PII S0002939402015490
    • Holkamp NM, Bouk N, Volpert O. Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. Am J Ophthalmol. 2002;134:220-7. (Pubitemid 34831826)
    • (2002) American Journal of Ophthalmology , vol.134 , Issue.2 , pp. 220-227
    • Holekamp, N.M.1    Bouck, N.2    Volpert, O.3
  • 24
    • 0036742063 scopus 로고    scopus 로고
    • Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy
    • Ogata N, Nishikawa M, Nishimura T, Mitsuma Y, Matsumura M. Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy. Am J Ophthalmol. 2002;134:348-53.
    • (2002) Am J Ophthalmol , vol.134 , pp. 348-353
    • Ogata, N.1    Nishikawa, M.2    Nishimura, T.3    Mitsuma, Y.4    Matsumura, M.5
  • 25
    • 11144239923 scopus 로고    scopus 로고
    • VEGF inhibition study in ocular neovascularization clinical trial group. Pegaptanib for neovascular age-related macular degeneration
    • Gragoudas ES, Adamis AP, Cunningham Jr ET, Feinsod M, Guyer DR. VEGF inhibition study in ocular neovascularization clinical trial group. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med. 2004;351:2805-16.
    • (2004) N Engl J Med , vol.351 , pp. 2805-2816
    • Gragoudas, E.S.1    Adamis, A.P.2    Cunningham Jr., E.T.3    Feinsod, M.4    Guyer, D.R.5
  • 27
    • 23044505200 scopus 로고    scopus 로고
    • Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration
    • Rosenfeld PJ, Moshfeghi AA, Puliafito CA. Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging. 2005;36:331-5. (Pubitemid 41073112)
    • (2005) Ophthalmic Surgery Lasers and Imaging , vol.36 , Issue.4 , pp. 331-335
    • Rosenfeld, P.J.1    Moshfeghi, A.A.2    Puliafito, C.A.3
  • 28
    • 36549016602 scopus 로고    scopus 로고
    • Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab
    • DOI 10.1016/j.ophtha.2007.09.008, PII S0161642007010263
    • Brantley Jr MA, Fang AM, King JM, Tewari A, Kymes SM, Shiels A. Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab. Ophthalmology. 2007;114:2168-73. (Pubitemid 350181136)
    • (2007) Ophthalmology , vol.114 , Issue.12 , pp. 2168-2173
    • Brantley Jr., M.A.1    Fang, A.M.2    King, J.M.3    Tewari, A.4    Kymes, S.M.5    Shiels, A.6
  • 29
    • 66149089631 scopus 로고    scopus 로고
    • Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab
    • Lee AY, Raya AK, Kymes SM, Shiels A, Brantley MA Jr. Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab. Br J Ophthalmol. 2009;93:610-3.
    • (2009) Br J Ophthalmol , vol.93 , pp. 610-613
    • Lee, A.Y.1    Raya, A.K.2    Kymes, S.M.3    Shiels, A.4    Brantley Jr., M.A.5
  • 30
    • 0036316846 scopus 로고    scopus 로고
    • A common polymorphism in the 5′-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes
    • Awata T, Inoue K, Kurihara S, Ohkubo T, Watanabe M, Inukai K, et al. A common polymorphism in the 5′-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes. Diabetes. 2002;51:1635-9. (Pubitemid 34826636)
    • (2002) Diabetes , vol.51 , Issue.5 , pp. 1635-1639
    • Awata, T.1    Inoue, K.2    Kurihara, S.3    Ohkubo, T.4    Watanabe, M.5    Inukai, K.6    Inoue, I.7    Katayama, S.8
  • 35
    • 77951622654 scopus 로고    scopus 로고
    • Phenotype and genotype characteristics of agerelated macular degeneration in a Japanese population
    • Mori K, Horie-Inoue K, Gehlbach PL, Takita H, Kabasawa S, Kawasaki I, et al. Phenotype and genotype characteristics of agerelated macular degeneration in a Japanese population. Ophthalmology. 2010;117:928-38.
    • (2010) Ophthalmology , vol.117 , pp. 928-938
    • Mori, K.1    Horie-Inoue, K.2    Gehlbach, P.L.3    Takita, H.4    Kabasawa, S.5    Kawasaki, I.6
  • 36
    • 79955871185 scopus 로고    scopus 로고
    • Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration
    • in press
    • Tsuchihashi T, Mori K, Horie-Inoue K, Gehlbach PL, Kabasawa S, Takita H, et al. Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration. Ophthalmology. 2010;117: in press.
    • (2010) Ophthalmology , pp. 117
    • Tsuchihashi, T.1    Mori, K.2    Horie-Inoue, K.3    Gehlbach, P.L.4    Kabasawa, S.5    Takita, H.6
  • 37
    • 54949086693 scopus 로고    scopus 로고
    • Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration
    • Boekhorn SS, Isaacs A, Uitterlinden AG, van Duijn CM, Hofman A, de Jong PT, et al. Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration. Ophthalmology. 2008;115:1899-903.
    • (2008) Ophthalmolog , vol.115 , pp. 1899-1903
    • Boekhorn, S.S.1    Isaacs, A.2    Uitterlinden, A.G.3    Van Duijn, C.M.4    Hofman, A.5    De Jong, P.T.6
  • 38
    • 53749093040 scopus 로고    scopus 로고
    • Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100
    • Schneider BP, Wang M, Radovich M, Sledge GW, Badve S, Thor A, et al. Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100. J Clin Oncol. 2008;26:4672-8.
    • (2008) J Clin Oncol , vol.26 , pp. 4672-4678
    • Schneider, B.P.1    Wang, M.2    Radovich, M.3    Sledge, G.W.4    Badve, S.5    Thor, A.6
  • 39
    • 69949107753 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor genetic variability in cancer
    • Schneider BP, Radovich M, Miller KD. The role of vascular endothelial growth factor genetic variability in cancer. Clin Cancer Res. 2009;15:5297-302.
    • (2009) Clin Cancer Res , vol.15 , pp. 5297-5302
    • Schneider, B.P.1    Radovich, M.2    Miller, K.D.3
  • 40
    • 30344447284 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration
    • DOI 10.1016/j.exer.2005.05.007, PII S0014483505001582
    • Bhutto IA, McLeod DS, Hasegawa T, Kim SY, Merges C, Tong P, et al. Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration. Exp Eye Res. 2006;82:99-110. (Pubitemid 43063401)
    • (2006) Experimental Eye Research , vol.82 , Issue.1 , pp. 99-110
    • Bhutto, I.A.1    McLeod, D.S.2    Hasegawa, T.3    Kim, S.Y.4    Merges, C.5    Tong, P.6    Lutty, G.A.7
  • 41
    • 0036329579 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration
    • DOI 10.1016/S0002-9394(02)01549-0, PII S0002939402015490
    • Holekamp NM, Bouck N, Volpert O. Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. Am J Ophthalmol. 2002;134:220-7. (Pubitemid 34831826)
    • (2002) American Journal of Ophthalmology , vol.134 , Issue.2 , pp. 220-227
    • Holekamp, N.M.1    Bouck, N.2    Volpert, O.3
  • 44
    • 34250780749 scopus 로고    scopus 로고
    • Clinical characteristics of exudative age-related macular degeneration in Japanese patients
    • Maruko I, Iida T, Saito M, Nagayama D, Saito K. Clinical characteristics of exudative age-related macular degeneration in Japanese patients. Am J Ophthalmol. 2007;144:15-22.
    • (2007) Am J Ophthalmol , vol.144 , pp. 15-22
    • Maruko, I.1    Iida, T.2    Saito, M.3    Nagayama, D.4    Saito, K.5
  • 45
    • 33645704085 scopus 로고    scopus 로고
    • Photodynamic therapy in macular diseases of Asian populations: When East meets West
    • Chan WM, Lai TY, Tano Y, Liu DTL, Li KKW, Lam DS. Photodynamic therapy in macular diseases of Asian populations: when East meets West. Jpn J Ophthalmol. 2006;50:161-9.
    • (2006) Jpn J Ophthalmol , vol.50 , pp. 161-169
    • Chan, W.M.1    Lai, T.Y.2    Tano, Y.3    Liu, D.T.L.4    Li, K.K.W.5    Lam, D.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.