-
1
-
-
54149084585
-
Multiple sclerosis
-
Compston A, Coles A, (2008) Multiple sclerosis. Lancet 372: 1502-1517.
-
(2008)
Lancet
, vol.372
, pp. 1502-1517
-
-
Compston, A.1
Coles, A.2
-
2
-
-
0037983828
-
Long-term follow up of patients with clinically isolated syndromes, relapsing-remitting and secondary progressive multiple sclerosis
-
Eriksson M, Andersen O, Runmarker B, (2003) Long-term follow up of patients with clinically isolated syndromes, relapsing-remitting and secondary progressive multiple sclerosis. Mult Scler 9: 260-274.
-
(2003)
Mult Scler
, vol.9
, pp. 260-274
-
-
Eriksson, M.1
Andersen, O.2
Runmarker, B.3
-
4
-
-
31544467633
-
The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy
-
Coles AJ, Cox A, Le Page E, Jones J, Trip SA, et al. (2006) The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J Neurol 253: 98-108.
-
(2006)
J Neurol
, vol.253
, pp. 98-108
-
-
Coles, A.J.1
Cox, A.2
Le Page, E.3
Jones, J.4
Trip, S.A.5
-
5
-
-
18544374335
-
Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study
-
Fassas A, Passweg JR, Anagnostopoulos A, Kazis A, Kozak T, et al. (2002) Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study. J Neurol 249: 1088-1097.
-
(2002)
J Neurol
, vol.249
, pp. 1088-1097
-
-
Fassas, A.1
Passweg, J.R.2
Anagnostopoulos, A.3
Kazis, A.4
Kozak, T.5
-
6
-
-
0029913882
-
Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis
-
Lublin FD, Reingold SC, (1996) Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 46: 907-911.
-
(1996)
Neurology
, vol.46
, pp. 907-911
-
-
Lublin, F.D.1
Reingold, S.C.2
-
7
-
-
73349109797
-
Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS
-
Sellebjerg F, Bornsen L, Khademi M, Krakauer M, Olsson T, et al. (2009) Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS. Neurology 73: 2003-2010.
-
(2009)
Neurology
, vol.73
, pp. 2003-2010
-
-
Sellebjerg, F.1
Bornsen, L.2
Khademi, M.3
Krakauer, M.4
Olsson, T.5
-
8
-
-
77949904336
-
Neurofilament light as a prognostic marker in multiple sclerosis
-
Salzer J, Svenningsson A, Sundstrom P, (2010) Neurofilament light as a prognostic marker in multiple sclerosis. Mult Scler 16: 287-292.
-
(2010)
Mult Scler
, vol.16
, pp. 287-292
-
-
Salzer, J.1
Svenningsson, A.2
Sundstrom, P.3
-
9
-
-
77952991177
-
Complement regulator factor H as a serum biomarker of multiple sclerosis disease state
-
Ingram G, Hakobyan S, Hirst CL, Harris CL, Pickersgill TP, et al. (2010) Complement regulator factor H as a serum biomarker of multiple sclerosis disease state. Brain 133: 1602-1611.
-
(2010)
Brain
, vol.133
, pp. 1602-1611
-
-
Ingram, G.1
Hakobyan, S.2
Hirst, C.L.3
Harris, C.L.4
Pickersgill, T.P.5
-
10
-
-
2342667384
-
New roles for VEGF in nervous tissue-beyond blood vessels
-
Rosenstein JM, Krum JM, (2004) New roles for VEGF in nervous tissue-beyond blood vessels. Exp Neurol 187: 246-253.
-
(2004)
Exp Neurol
, vol.187
, pp. 246-253
-
-
Rosenstein, J.M.1
Krum, J.M.2
-
12
-
-
0034978562
-
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
-
Oosthuyse B, Moons L, Storkebaum E, Beck H, Nuyens D, et al. (2001) Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet 28: 131-138.
-
(2001)
Nat Genet
, vol.28
, pp. 131-138
-
-
Oosthuyse, B.1
Moons, L.2
Storkebaum, E.3
Beck, H.4
Nuyens, D.5
-
13
-
-
0036167595
-
Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia
-
Tarkowski E, Issa R, Sjogren M, Wallin A, Blennow K, et al. (2002) Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia. Neurobiol Aging 23: 237-243.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 237-243
-
-
Tarkowski, E.1
Issa, R.2
Sjogren, M.3
Wallin, A.4
Blennow, K.5
-
14
-
-
2642526164
-
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
-
Azzouz M, Ralph GS, Storkebaum E, Walmsley LE, Mitrophanous KA, et al. (2004) VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 429: 413-417.
-
(2004)
Nature
, vol.429
, pp. 413-417
-
-
Azzouz, M.1
Ralph, G.S.2
Storkebaum, E.3
Walmsley, L.E.4
Mitrophanous, K.A.5
-
15
-
-
1242338809
-
Co-accumulation of vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease
-
Yang SP, Bae DG, Kang HJ, Gwag BJ, Gho YS, et al. (2004) Co-accumulation of vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease. Neurobiol Aging 25: 283-290.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 283-290
-
-
Yang, S.P.1
Bae, D.G.2
Kang, H.J.3
Gwag, B.J.4
Gho, Y.S.5
-
16
-
-
16644382257
-
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
-
Storkebaum E, Lambrechts D, Dewerchin M, Moreno-Murciano MP, Appelmans S, et al. (2005) Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat Neurosci 8: 85-92.
-
(2005)
Nat Neurosci
, vol.8
, pp. 85-92
-
-
Storkebaum, E.1
Lambrechts, D.2
Dewerchin, M.3
Moreno-Murciano, M.P.4
Appelmans, S.5
-
17
-
-
57749196007
-
Meta-analysis of VEGF variations in ALS: increased susceptibility in male carriers of the -2578AA genotype
-
Lambrechts D, Poesen K, Fernandez-Santiago R, Al-Chalabi A, Del Bo R, et al. (2008) Meta-analysis of VEGF variations in ALS: increased susceptibility in male carriers of the -2578AA genotype. J Med Genet.
-
(2008)
J Med Genet
-
-
Lambrechts, D.1
Poesen, K.2
Fernandez-Santiago, R.3
Al-Chalabi, A.4
Del Bo, R.5
-
18
-
-
67650149742
-
VEGF genetic variability is associated with increased risk of developing Alzheimer's disease
-
Del Bo R, Ghezzi S, Scarpini E, Bresolin N, Comi GP, (2009) VEGF genetic variability is associated with increased risk of developing Alzheimer's disease. J Neurol Sci 283: 66-68.
-
(2009)
J Neurol Sci
, vol.283
, pp. 66-68
-
-
Del Bo, R.1
Ghezzi, S.2
Scarpini, E.3
Bresolin, N.4
Comi, G.P.5
-
19
-
-
0036794017
-
Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis rats
-
Proescholdt MA, Jacobson S, Tresser N, Oldfield EH, Merrill MJ, (2002) Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis rats. J Neuropathol Exp Neurol 61: 914-925.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 914-925
-
-
Proescholdt, M.A.1
Jacobson, S.2
Tresser, N.3
Oldfield, E.H.4
Merrill, M.J.5
-
20
-
-
0242667881
-
Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult
-
Graumann U, Reynolds R, Steck AJ, Schaeren-Wiemers N, (2003) Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult. Brain Pathol 13: 554-573.
-
(2003)
Brain Pathol
, vol.13
, pp. 554-573
-
-
Graumann, U.1
Reynolds, R.2
Steck, A.J.3
Schaeren-Wiemers, N.4
-
21
-
-
33645092394
-
Upregulation of vascular growth factors in multiple sclerosis: correlation with MRI findings
-
Su JJ, Osoegawa M, Matsuoka T, Minohara M, Tanaka M, et al. (2006) Upregulation of vascular growth factors in multiple sclerosis: correlation with MRI findings. J Neurol Sci 243: 21-30.
-
(2006)
J Neurol Sci
, vol.243
, pp. 21-30
-
-
Su, J.J.1
Osoegawa, M.2
Matsuoka, T.3
Minohara, M.4
Tanaka, M.5
-
22
-
-
33750688816
-
Decreased expression of VEGF-A in rat experimental autoimmune encephalomyelitis and in cerebrospinal fluid mononuclear cells from patients with multiple sclerosis
-
Tham E, Gielen AW, Khademi M, Martin C, Piehl F, (2006) Decreased expression of VEGF-A in rat experimental autoimmune encephalomyelitis and in cerebrospinal fluid mononuclear cells from patients with multiple sclerosis. Scand J Immunol 64: 609-622.
-
(2006)
Scand J Immunol
, vol.64
, pp. 609-622
-
-
Tham, E.1
Gielen, A.W.2
Khademi, M.3
Martin, C.4
Piehl, F.5
-
23
-
-
68049137625
-
VEGF and mRNA VEGF expression in CSF from Behcet's disease with neurological involvement
-
Hamzaoui K, Ayed K, Hamza M, Hamzaoui A, (2009) VEGF and mRNA VEGF expression in CSF from Behcet's disease with neurological involvement. J Neuroimmunol 213: 148-153.
-
(2009)
J Neuroimmunol
, vol.213
, pp. 148-153
-
-
Hamzaoui, K.1
Ayed, K.2
Hamza, M.3
Hamzaoui, A.4
-
24
-
-
28544436950
-
Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria"
-
Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, et al. (2005) Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 58: 840-846.
-
(2005)
Ann Neurol
, vol.58
, pp. 840-846
-
-
Polman, C.H.1
Reingold, S.C.2
Edan, G.3
Filippi, M.4
Hartung, H.P.5
-
25
-
-
65349157666
-
Combination of CSF N-acetylaspartate and neurofilaments in multiple sclerosis
-
Teunissen CE, Iacobaeus E, Khademi M, Brundin L, Norgren N, et al. (2009) Combination of CSF N-acetylaspartate and neurofilaments in multiple sclerosis. Neurology 72: 1322-1329.
-
(2009)
Neurology
, vol.72
, pp. 1322-1329
-
-
Teunissen, C.E.1
Iacobaeus, E.2
Khademi, M.3
Brundin, L.4
Norgren, N.5
-
26
-
-
34548368541
-
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis
-
Lundmark F, Duvefelt K, Iacobaeus E, Kockum I, Wallstrom E, et al. (2007) Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet 39: 1108-1113.
-
(2007)
Nat Genet
, vol.39
, pp. 1108-1113
-
-
Lundmark, F.1
Duvefelt, K.2
Iacobaeus, E.3
Kockum, I.4
Wallstrom, E.5
-
27
-
-
0020686503
-
New diagnostic criteria for multiple sclerosis: guidelines for research protocols
-
Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, et al. (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13: 227-231.
-
(1983)
Ann Neurol
, vol.13
, pp. 227-231
-
-
Poser, C.M.1
Paty, D.W.2
Scheinberg, L.3
McDonald, W.I.4
Davis, F.A.5
-
28
-
-
34047179603
-
SNPassoc: an R package to perform whole genome association studies
-
Gonzalez JR, Armengol L, Sole X, Guino E, Mercader JM, et al. (2007) SNPassoc: an R package to perform whole genome association studies. Bioinformatics 23: 644-645.
-
(2007)
Bioinformatics
, vol.23
, pp. 644-645
-
-
Gonzalez, J.R.1
Armengol, L.2
Sole, X.3
Guino, E.4
Mercader, J.M.5
-
29
-
-
12244264435
-
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
-
Purcell S, Cherny SS, Sham PC, (2003) Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19: 149-150.
-
(2003)
Bioinformatics
, vol.19
, pp. 149-150
-
-
Purcell, S.1
Cherny, S.S.2
Sham, P.C.3
-
30
-
-
67650032747
-
Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells
-
Kivisakk P, Healy BC, Viglietta V, Quintana FJ, Hootstein MA, et al. (2009) Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells. Neurology 72: 1922-1930.
-
(2009)
Neurology
, vol.72
, pp. 1922-1930
-
-
Kivisakk, P.1
Healy, B.C.2
Viglietta, V.3
Quintana, F.J.4
Hootstein, M.A.5
-
31
-
-
67649973540
-
Role and therapeutic potential of VEGF in the nervous system
-
Ruiz de Almodovar C, Lambrechts D, Mazzone M, Carmeliet P, (2009) Role and therapeutic potential of VEGF in the nervous system. Physiol Rev 89: 607-648.
-
(2009)
Physiol Rev
, vol.89
, pp. 607-648
-
-
de Ruiz Almodovar, C.1
Lambrechts, D.2
Mazzone, M.3
Carmeliet, P.4
-
32
-
-
70350044493
-
Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis
-
Vogt J, Paul F, Aktas O, Muller-Wielsch K, Dorr J, et al. (2009) Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Ann Neurol 66: 310-322.
-
(2009)
Ann Neurol
, vol.66
, pp. 310-322
-
-
Vogt, J.1
Paul, F.2
Aktas, O.3
Muller-Wielsch, K.4
Dorr, J.5
-
33
-
-
78650348569
-
Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions
-
Seabrook TJ, Littlewood-Evans A, Brinkmann V, Pollinger B, Schnell C, et al. (2010) Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions. J Neuroinflammation 7: 95.
-
(2010)
J Neuroinflammation
, vol.7
, pp. 95
-
-
Seabrook, T.J.1
Littlewood-Evans, A.2
Brinkmann, V.3
Pollinger, B.4
Schnell, C.5
-
34
-
-
2342667380
-
VEGF-mediated inflammation precedes angiogenesis in adult brain
-
Croll SD, Ransohoff RM, Cai N, Zhang Q, Martin FJ, et al. (2004) VEGF-mediated inflammation precedes angiogenesis in adult brain. Exp Neurol 187: 388-402.
-
(2004)
Exp Neurol
, vol.187
, pp. 388-402
-
-
Croll, S.D.1
Ransohoff, R.M.2
Cai, N.3
Zhang, Q.4
Martin, F.J.5
-
35
-
-
2642569472
-
Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis
-
Manoonkitiwongsa PS, Schultz RL, McCreery DB, Whitter EF, Lyden PD, (2004) Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis. J Cereb Blood Flow Metab 24: 693-702.
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, pp. 693-702
-
-
Manoonkitiwongsa, P.S.1
Schultz, R.L.2
McCreery, D.B.3
Whitter, E.F.4
Lyden, P.D.5
-
36
-
-
0242574486
-
VEGF and vascular changes in chronic neuroinflammation
-
Kirk SL, Karlik SJ, (2003) VEGF and vascular changes in chronic neuroinflammation. J Autoimmun 21: 353-363.
-
(2003)
J Autoimmun
, vol.21
, pp. 353-363
-
-
Kirk, S.L.1
Karlik, S.J.2
-
37
-
-
1642348866
-
Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization
-
Mor F, Quintana FJ, Cohen IR, (2004) Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization. J Immunol 172: 4618-4623.
-
(2004)
J Immunol
, vol.172
, pp. 4618-4623
-
-
Mor, F.1
Quintana, F.J.2
Cohen, I.R.3
-
38
-
-
78650348569
-
Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions
-
Seabrook TJ, Littlewood-Evans A, Brinkmann V, Pollinger B, Schnell C, et al. Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions. J Neuroinflammation 7: 95.
-
J Neuroinflammation
, vol.7
, pp. 95
-
-
Seabrook, T.J.1
Littlewood-Evans, A.2
Brinkmann, V.3
Pollinger, B.4
Schnell, C.5
-
39
-
-
0346101871
-
Impact of type-I-interferon on monocyte subsets and their differentiation to dendritic cells. An in vivo and ex vivo study in multiple sclerosis patients treated with interferon-beta
-
Then Bergh F, Dayyani F, Ziegler-Heitbrock L, (2004) Impact of type-I-interferon on monocyte subsets and their differentiation to dendritic cells. An in vivo and ex vivo study in multiple sclerosis patients treated with interferon-beta. J Neuroimmunol 146: 176-188.
-
(2004)
J Neuroimmunol
, vol.146
, pp. 176-188
-
-
Then Bergh, F.1
Dayyani, F.2
Ziegler-Heitbrock, L.3
-
40
-
-
0035164119
-
Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis
-
Cepok S, Jacobsen M, Schock S, Omer B, Jaekel S, et al. (2001) Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis. Brain 124: 2169-2176.
-
(2001)
Brain
, vol.124
, pp. 2169-2176
-
-
Cepok, S.1
Jacobsen, M.2
Schock, S.3
Omer, B.4
Jaekel, S.5
-
41
-
-
0031027581
-
Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand
-
Balashov KE, Smith DR, Khoury SJ, Hafler DA, Weiner HL, (1997) Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand. Proc Natl Acad Sci U S A 94: 599-603.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 599-603
-
-
Balashov, K.E.1
Smith, D.R.2
Khoury, S.J.3
Hafler, D.A.4
Weiner, H.L.5
-
42
-
-
69049084375
-
Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
-
Farez MF, Quintana FJ, Gandhi R, Izquierdo G, Lucas M, et al. (2009) Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE. Nat Immunol 10: 958-964.
-
(2009)
Nat Immunol
, vol.10
, pp. 958-964
-
-
Farez, M.F.1
Quintana, F.J.2
Gandhi, R.3
Izquierdo, G.4
Lucas, M.5
-
43
-
-
33644974688
-
Secondary progressive multiple sclerosis: current knowledge and future challenges
-
Rovaris M, Confavreux C, Furlan R, Kappos L, Comi G, et al. (2006) Secondary progressive multiple sclerosis: current knowledge and future challenges. Lancet Neurol 5: 343-354.
-
(2006)
Lancet Neurol
, vol.5
, pp. 343-354
-
-
Rovaris, M.1
Confavreux, C.2
Furlan, R.3
Kappos, L.4
Comi, G.5
-
44
-
-
55349135951
-
Novel therapeutic strategies for multiple sclerosis-a multifaceted adversary
-
Lopez-Diego RS, Weiner HL, (2008) Novel therapeutic strategies for multiple sclerosis-a multifaceted adversary. Nat Rev Drug Discov 7: 909-925.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 909-925
-
-
Lopez-Diego, R.S.1
Weiner, H.L.2
-
45
-
-
0036138599
-
Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection
-
Shahbazi M, Fryer AA, Pravica V, Brogan IJ, Ramsay HM, et al. (2002) Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection. J Am Soc Nephrol 13: 260-264.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 260-264
-
-
Shahbazi, M.1
Fryer, A.A.2
Pravica, V.3
Brogan, I.J.4
Ramsay, H.M.5
-
46
-
-
0041903805
-
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
-
Lambrechts D, Storkebaum E, Morimoto M, Del-Favero J, Desmet F, et al. (2003) VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet 34: 383-394.
-
(2003)
Nat Genet
, vol.34
, pp. 383-394
-
-
Lambrechts, D.1
Storkebaum, E.2
Morimoto, M.3
Del-Favero, J.4
Desmet, F.5
|