Clonidine as adjuvant for oxybuprocaine, bupivacaine or dextrorphan has a significant peripheral action in intensifying and prolonging analgesia in response to local dorsal cutaneous noxious pinprick in rats

Neuroscience Letters

Volumn 496, Issue 3, 2011, Pages 186-190

  Chen, Yu Wen ^a   Chu, Chin Chen ^b   Chen, Yu Chung ^c   Hung, Ching Hsia ^d   Hsueh, Meng I ^a   Wang, Jhi Joung ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Bupivacaine; Clonidine; Dextrorphan; Infiltrative cutaneous analgesia; Oxybuprocaine

Indexed keywords

BUPIVACAINE; CLONIDINE; DEXTRORPHAN; OXYBUPROCAINE;

ANALGESIC ACTIVITY; ANESTHESIA LEVEL; ANIMAL EXPERIMENT; ARTICLE; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG POTENTIATION; LOCAL ANESTHESIA; MALE; MUSCLE REFLEX; NERVE BLOCK; NOCICEPTIVE STIMULATION; NONHUMAN; PRICK TEST; PRIORITY JOURNAL; RAT; SKIN SENSITIVITY;

ADJUVANTS, ANESTHESIA; ADRENERGIC ALPHA-AGONISTS; ANALGESIA; ANESTHETICS, LOCAL; ANIMALS; AREA UNDER CURVE; BUPIVACAINE; CLONIDINE; DATA INTERPRETATION, STATISTICAL; DEXTRORPHAN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EXCITATORY AMINO ACID ANTAGONISTS; INJECTIONS, SUBCUTANEOUS; MALE; PAIN; PERIPHERAL NERVES; PHYSICAL STIMULATION; PROCAINE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79955774308     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.04.021     Document Type: Article

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