The dose-dependent study of verapamil and diltiazem on spinal anesthesia in the rat

Neuroscience Letters

Volumn 482, Issue 1, 2010, Pages 76-80

  Chen, Yu Wen ^a   Chu, Chin Chen ^b   Chen, Yu Chung ^c   Wang, Jhi Joung ^b   Hung, Ching Hsia ^b,d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^d NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Diltiazem; Mepivacaine; Spinal anesthesia; Verapamil

Indexed keywords

DILTIAZEM; LOCAL ANESTHETIC AGENT; MEPIVACAINE; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; MALE; MOTOR ACTIVITY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROPRIOCEPTION; RAT; SPINAL ANESTHESIA;

EID: 77955549353     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.011     Document Type: Article

References (20)

1. 2+ channel inhibitor acts as a local anesthetic and induces the sigma E dependent extra-cytoplasmic stress response in E. coli. Biochim. Biophys. Acta 2006, 1758:1587-1595.
2. Arioka I., Dohi S., Sakai K. Prognostic effects of calcium channel blockers on cardiac events, stroke and end-stage renal disease in patients with angina pectoris. Retrospective comparative study of benidipine, diltiazem and nifedipine. Arzneimittelforschung 2008, 58:435-440.
3. Chen Y.W., Chen Y.C., Lin C.N., Chu C.C., Lin M.T., Wang J.J., Kao C.H. The spinal anaesthetic effect of dextromethorphan, dextrorphan, and 3-methoxymorphinan. Eur. J. Pharmacol. 2007, 569:188-193.
4. Chen Y.W., Chu C.C., Chen Y.C., Wang J.J., Hung C.H. Isobolographic analysis of caramiphen and lidocaine on spinal anesthesia in rats. Neurosci. Lett. 2010, 469:174-178.
5. Dietz J.D., Du S., Bolten C.W., Payne M.A., Xia C., Blinn J.R., Funder J.W., Hu X. A number of marketed dihydropyridine calcium channel blockers have mineralocorticoid receptor antagonist activity. Hypertension 2008, 51:742-748.
6. Fleckenstein A. Historical overview. The calcium channel of the heart. Ann. N. Y. Acad. Sci. 1988, 522:1-15.
7. Gurlit S., Reinhardt S., Mollmann M. Continuous spinal analgesia or opioid-added continuous epidural analgesia for postoperative pain control after hip replacement. Eur. J. Anaesthesiol. 2004, 21:708-714.
8. Hashimoto Y., Yabana H., Murata S. Electrophysiological effect of l-cis-diltiazem, the stereoisomer of d-cis-diltiazem, on isolated guinea-pig left ventricular myocytes. Eur. J. Pharmacol. 2000, 391:217-223.
9. Hondeghem L.M., Katzung B.G. Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs. Annu. Rev. Pharmacol. Toxicol. 1984, 24:387-423.
10. Hung C.H., Wang J.J., Chen Y.C., Chu C.C., Chen Y.W. Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats. Neurosci. Lett. 2009, 454:249-253.
11. Jawaid M., Masood Z., Salim M. Topical diltiazem hydrochloride and glyceryl trinitrate in the treatment of chronic anal fissure. J. Coll. Physicians Surg. Pak. 2009, 19:614-617.
12. Laurito C.E., Cohn S.J., Becker G.L. Effects of subcutaneous verapamil on the duration of local anesthetic blockade. J. Clin. Anesth. 1994, 6:414-418.
13. Leszczynska K., Kau S.T. A sciatic nerve blockade method to differentiate drug-induced local anesthesia from neuromuscular blockade in mice. J. Pharmacol. Toxicol. Methods 1992, 27:85-93.
14. McLure H.A., Rubin A.P. Review of local anaesthetic agents. Minerva Anestesiol. 2005, 71:59-74.
15. Omote K., Iwasaki H., Kawamata M., Satoh O., Namiki A. Effects of verapamil on spinal anesthesia with local anesthetics. Anesth. Analg. 1995, 80:444-448.
16. Pidoplichko V.I., Verkhratskii A.N. Frequency-related blocking of sodium channels in the membrane of isolated rat cardiomyocytes by the calcium antagonist verapamil. Fiziol. Zh. 1989, 35:87-89.
17. + channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs. Mol. Pharmacol. 1991, 40:756-765.
18. Roger S., Le Guennec J.Y., Besson P. Particular sensitivity to calcium channel blockers of the fast inward voltage-dependent sodium current involved in the invasive properties of a metastastic breast cancer cell line. Br. J. Pharmacol. 2004, 141:610-615.
19. Scholz A. Mechanisms of (local) anaesthetics on voltage-gated sodium and other ion channels. Br. J. Anaesth. 2002, 89:52-61.
20. Sheets M.F., Hanck D.A. Molecular action of lidocaine on the voltage sensors of sodium channels. J. Gen. Physiol. 2003, 121:163-175.