The systemic toxicity of equipotent proxymetacaine, oxybuprocaine, and bupivacaine during continuous intravenous infusion in rats

Anesthesia and Analgesia

Volumn 110, Issue 1, 2010, Pages 238-242

  Hung, Ching Hsia ^a   Liu, Kuo Sheng ^b   Shao, Dong Zi ^c   Cheng, Kuang I ^d   Chen, Yu Chung ^e   Chen, Yu Wen ^f  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^c CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e CHENG HSIN REHABILITATION MEDICAL CENTER   (Taiwan)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; OXYBUPROCAINE; PENTOBARBITAL; PROXYMETACAINE; DRUG DERIVATIVE; LOCAL ANESTHETIC AGENT; PROCAINE; PROPOXYCAINE;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; APNEA; ARTICLE; BRAIN TOXICITY; CARDIOTOXICITY; CENTRAL NERVOUS SYSTEM; COMPARATIVE STUDY; CONTINUOUS INFUSION; CONTROLLED STUDY; DEATH; DRUG INFUSION; HEART RATE; INJECTION; MALE; MEAN ARTERIAL PRESSURE; MONITORING; MUSCLE REFLEX; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; SKIN; TRUNK; ANIMAL; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; HEMODYNAMICS; INTRAVENOUS DRUG ADMINISTRATION; PAIN ASSESSMENT; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TOXICITY AND INTOXICATION;

ANALGESIA; ANESTHETICS, LOCAL; ANIMALS; BUPIVACAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMODYNAMICS; INFUSIONS, INTRAVENOUS; MALE; NEUROTOXICITY SYNDROMES; PAIN MEASUREMENT; PROCAINE; PROPOXYCAINE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES;

EID: 74049146731     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3181bf6acf     Document Type: Article

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