Systemic dextromethorphan and dextrorphan are less toxic in rats than bupivacaine at equianesthetic doses

Canadian Journal of Anesthesia

Volumn 58, Issue 1, 2011, Pages 55-61

  Chen, Yu Wen ^a,b   Wang, Jhi Joung ^b   Liu, Tzu Ying ^c   Chen, Yu Chung ^d   Hung, Ching Hsia ^c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d CHENG HSIN GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; DEXTROMETHORPHAN; DEXTRORPHAN;

ANALGESIA; ANALGESIC ACTIVITY; ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; APNEA; AREA UNDER THE CURVE; ARTICLE; CARDIOTOXICITY; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REDUCTION; DRUG POTENCY; HEART ARREST; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; LOCAL ANESTHESIA; MALE; MEAN ARTERIAL PRESSURE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; SHOCK;

ANESTHETICS, LOCAL; ANIMALS; APNEA; BUPIVACAINE; DEXTROMETHORPHAN; DEXTRORPHAN; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; HEART ARREST; INFUSIONS, INTRAVENOUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; TIME FACTORS;

EID: 78751575314     PISSN: 0832610X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12630-010-9408-z     Document Type: Article

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