Aging attenuates the vasodilator response to relaxin

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 5, 2011, Pages

  van Drongelen, Joris ^a   Ploemen, Ivo H J ^a   Pertijs, Jeanne ^a   Gooi, Jonathan H ^b   Sweep, Fred C G J ^a   Lotgering, Frederik K ^a   Spaanderman, Marc E A ^a   Smits, Paul ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Human recombinant relaxin; Isolated perfused rat kidney; Mesenteric arteries; Relaxin resistance; Wistar hannover rats

Indexed keywords

GROWTH FACTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PLACEBO; PROTEIN RXFP1; RECOMBINANT RELAXIN; RELAXIN; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; BLOOD FLOW; BLOOD VESSEL COMPLIANCE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; KIDNEY; KIDNEY PERFUSION; MESENTERIC ARTERY; MUSCLE BLOOD FLOW; MYOGRAPHY; NONHUMAN; PERFUSION PRESSURE; POLYMERASE CHAIN REACTION; PRESSURE PERFUSION MYOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RENAL PERFUSION FLOW; VASCULAR ENDOTHELIUM; VASCULAR RESISTANCE; VASODILATATION; WIRE MYOGRAPHY;

AGING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FEMALE; MESENTERIC ARTERIES; MODELS, ANIMAL; NITRIC OXIDE; PHENYLEPHRINE; RATS; RATS, WISTAR; RELAXIN; RENAL ARTERY; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 79955768377     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00360.2010     Document Type: Article

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