Dealing with matrix effect: Should there be a cut-off limit for signal ion suppression in quantitative assay validation?

Biomedical Chromatography

Volumn 25, Issue 6, 2011, Pages 740-742

  Srinivas, Nuggehally R ^a  

^a Vanthys Pharmaceutical Development   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ION SUPPRESSION; MATRICES EFFECT; QUANTITATIVE ASSAY;

ACEBUTOLOL; CELECOXIB; DEUTERIUM; DOCETAXEL; DRL 16126; ETHINYLESTRADIOL; GESTODENE; ION; LABETALOL; LANSOPRAZOLE; METOPROLOL; NORGESTREL; OMEPRAZOLE; PINDOLOL; PROPRANOLOL; RHEIN; SILDENAFIL; TORCETRAPIB; UNCLASSIFIED DRUG;

ERROR; HUMAN; IONIZATION; LETTER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX EFFECT; NONHUMAN; PERFORMANCE; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REFERENCE VALUE; SIGNAL DETECTION; STANDARD; VALIDATION PROCESS;

EID: 79955766010     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1637     Document Type: Letter

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