Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers

Cancer Causes and Control

Volumn 22, Issue 3, 2011, Pages 449-461

  Sakoda, Lori C ^a,b   Loomis, Melissa M ^b   Doherty, Jennifer A ^a,b   Neuhouser, Marian L ^a   Barnett, Matt J ^a   Thornquist, Mark D ^a   Weiss, Noel S ^a   Goodman, Gary E ^a   Chen, Chu ^a,b,c  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Diet; Genetic polymorphism; Lung cancer; Nicotinic acetylcholine receptors

Indexed keywords

ADULT; AGE; AGED; AGPHD1 GENE; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; CHRNA3 GENE; CHRNA5 GENE; CHRNAB4 GENE; CHROMOSOME 15Q; CHROMOSOME VARIANT; CIGARETTE SMOKING; CONTROLLED STUDY; DIET; DIETARY INTAKE; FEMALE; FOOD FREQUENCY QUESTIONNAIRE; FRUIT; GENE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VEGETABLE;

ADENOCARCINOMA; AGED; ALLELES; BETA CAROTENE; CASE-CONTROL STUDIES; DIET; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; SMOKING;

EID: 79955753229     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-010-9716-1     Document Type: Article

References (34)

1. Bierut LJ, Madden PA, Breslau N et al (2007) Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet 16:24-35 (Pubitemid 46152542)
2. Hung RJ, McKay JD, Gaborieau V et al (2008) A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452:633-637 (Pubitemid 351483367)
3. Amos CI, Wu X, Broderick P et al (2008) Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 40:616-622 (Pubitemid 351601203)
4. Thorgeirsson TE, Geller F, Sulem P et al (2008) A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452:638-642 (Pubitemid 351483366)
5. Liu P, Vikis HG, Wang D et al (2008) Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst 100:1326-1330
6. Schuller HM (2009) Is cancer triggered by altered signalling of nicotinic acetylcholine receptors? Nat Rev Cancer 195-205
7. Schuller HM, Orloff M (1998) Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells. Biochem Pharmacol 55:1377-1384 (Pubitemid 28298517)
8. Spitz MR, Amos CI, Dong Q, Lin J, Wu X (2008) The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. J Natl Cancer Inst 100:1552-1556
9. Lips EH, Gaborieau V, McKay JD et al (2010) Association between a 15q25 gene variant, smoking quantity and tobaccorelated cancers among 17,000 individuals. Int J Epidemiol 39:563-577
10. Wang Y, Broderick P, Matakidou A, Eisen T, Houlston RS (2010) Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers. Carcinogenesis 31:234-238
11. Truong T, Hung RJ, Amos CI et al (2010) Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: A pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst 102:959-971
12. Vainio H, Weiderpass E (2006) Fruit and vegetables in cancer prevention. Nutr Cancer 54:111-142 (Pubitemid 44141342)
13. Buchner FL, Bueno-de-Mesquita HB, Ros MM et al (2010) Variety in fruit and vegetable consumption and the risk of lung cancer in the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomarkers Prev 19:2278-2286
14. Thornquist MD, Omenn GS, Goodman GE et al (1993) Statistical design and monitoring of the Carotene and Retinol Efficacy Trial (CARET). Control Clin Trials 14:308-324 (Pubitemid 23256749)
15. Omenn GS, Goodman GE, Thornquist MD et al (1996) Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 334:1150-1155 (Pubitemid 26137973)
16. Omenn GS, Goodman GE, Thornquist MD et al (1996) Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst 88:1550-1559 (Pubitemid 26374508)
17. Goodman GE, Thornquist MD, Balmes J et al (2004) The Beta- Carotene and Retinol Efficacy Trial: Incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping beta-carotene and retinol supplements. J Natl Cancer Inst 96:1743-1750 (Pubitemid 39654568)
18. Neuhouser ML, Patterson RE, Thornquist MD, Omenn GS, King IB, Goodman GE (2003) Fruits and vegetables are associated with lower lung cancer risk only in the placebo arm of the betacarotene and retinol efficacy trial (CARET). Cancer Epidemiol Biomarkers Prev 12:350-358 (Pubitemid 36427996)
19. Schakel SF, Buzzard IM, Gebhardt SE (1997) Procedures for estimating nutrient values for food composition databases. J Food Comp Anal 10:102-114 (Pubitemid 127341241)
20. Holden JM, Eldridge AL, Beecher GR et al (1999) Carotenoid content of U.S. foods: An update of the database. J Food Comp Anal 12:169-196 (Pubitemid 129567869)
21. Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA (2004) Selecting a maximally informative set of singlenucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 74:106-120 (Pubitemid 38085242)
22. Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265 (Pubitemid 40202029)
23. Stephens M, Donnelly P (2003) A comparison of Bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73:1162-1169 (Pubitemid 37414228)
24. Broderick P, Wang Y, Vijayakrishnan J et al (2009) Deciphering the impact of common genetic variation on lung cancer risk: A genome-wide association study. Cancer Res 69:6633-6641
25. Schwartz AG, Cote ML, Wenzlaff AS, Land S, Amos CI (2009) Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer. J Thoracic Oncol 4:1195-1201
26. Yang P, Li Y, Jiang R, Cunningham JM, Zhang F, de Andrade M (2010) A rigorous and comprehensive validation: Common genetic variations and lung cancer. Cancer Epidemiol Biomarkers Prev 19:240-244
27. Wang JC, Cruchaga C, Saccone NL et al (2009) Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet 18:3125-3135
28. Liu P, Yang P, Wu X et al (2010) A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. Cancer Res 70:3128-3135
29. Bierut LJ, Stitzel JA, Wang JC et al (2008) Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry 165:1163-1171
30. Stevens VL, Bierut LJ, Talbot JT et al (2008) Nicotinic receptor gene variants influence susceptibility to heavy smoking. Cancer Epidemiol Biomarkers Prev 17:3517-3525
31. Falvella FS, Galvan A, Colombo F, Frullanti E, Pastorino U, Dragani TA (2010) Promoter polymorphisms and transcript levels of nicotinic receptor CHRNA5. J Natl Cancer Inst 102: 1366-1370
32. Falvella FS, Galvan A, Frullanti E et al (2009) Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk. Clin Cancer Res 15:1837-1842
33. Liu Y, Liu P, Wen W et al (2009) Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. Cancer Res 69:7844-7850
34. De Stefani E, Boffetta P, Deneo-Pellegrini H et al (2009) Meat intake, meat mutagens and risk of lung cancer in Uruguayan men. Cancer Causes Control 20:1635-1643