Biochemical characterization of a protein tyrosine phosphatase from Trypanosoma cruzi involved in metacyclogenesis and cell invasion

Biochemical and Biophysical Research Communications

Volumn 408, Issue 3, 2011, Pages 427-431

  Gallo, Gloria ^a   Ramos, Thiago Cesar Prata ^a   Tavares, Fernanda ^b   Rocha, Antonio A ^a   Machi, Emerson ^b   Schenkman, Sergio ^a   Bahia, Diana ^a   Pesquero, João Bosco ^a   Wurtele Martin M ^a,b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b LABORATÓRIO NACIONAL DE LUZ SÍNCROTRON   (Brazil)

Author keywords

Chagas' disease; Protein tyrosine phosphatase; Recombinant expression; Trypanosoma cruzi

Indexed keywords

BENZNIDAZOLE; NIFURTIMOX; PROTEIN TYROSINE PHOSPHATASE;

AFFINITY CHROMATOGRAPHY; ARTICLE; CELL CYCLE; CHAGAS DISEASE; DRUG TARGETING; ENZYME ANALYSIS; ENZYME PURIFICATION; ESCHERICHIA COLI; HOST PARASITE INTERACTION; KINETOPLASTIDA; MICHAELIS MENTEN KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRYPANOSOMA CRUZI;

CELL CYCLE; PROTEIN TYROSINE PHOSPHATASES; TRYPANOSOMA CRUZI;

ESCHERICHIA COLI; EUKARYOTA; TRYPANOSOMA CRUZI;

EID: 79955749860     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.04.038     Document Type: Article

References (32)

1. Zhang Z.Y. Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development. Annu. Rev. Pharmacol. Toxicol. 2002, 42:209-234.
2. Andersen J.N., Mortensen O.H., Peters G.H., Drake P.G., Iversen L.F., Olsen O.H., Jansen P.G., Andersen H.S., Tonks N.K., Moller N.P. Structural and evolutionary relationships among protein tyrosine phosphatase domains. Mol. Cell. Biol. 2001, 21:7117-7136.
3. Gurtler R.E., Diotaiuti L., Kitron U. Commentary: chagas disease: 100 years since discovery and lessons for the future. Int. J. Epidemiol. 2008, 37:698-701.
4. Lima F.M., Oliveira P., Mortara R.A., Silveira J.F., Bahia D. The challenge of Chagas' disease: has the human pathogen, Trypanosoma cruzi, learned how to modulate signaling events to subvert host cells?. N. Biotechnol. 2010, 27:837-843.
5. Brenchley R., Tariq H., McElhinney H., Szoor B., Huxley-Jones J., Stevens R., Matthews K., Tabernero L. The TriTryp phosphatome: analysis of the protein phosphatase catalytic domains. BMC Genom. 2007, 8:434.
6. Barford D., Flint A.J., Tonks N.K. Crystal structure of human protein tyrosine phosphatase 1B. Science 1994, 263:1397-1404.
7. Szoor B., Wilson J., McElhinney H., Tabernero L., Matthews K.R. Protein tyrosine phosphatase TbPTP1: a molecular switch controlling life cycle differentiation in trypanosomes. J. Cell Biol. 2006, 175:293-303.
8. Szoor B., Ruberto I., Burchmore R., Matthews K.R. A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway. Genes Dev. 2010, 24:1306-1316.
9. Bakalara N., Seyfang A., Baltz T., Davis C. Trypanosoma brucei and Trypanosoma cruzi: life cycle-regulated protein tyrosine phosphatase activity. Exp. Parasitol. 1995, 81:302-312.
10. Chou J.B., Parsons M., Alber T., Grundner C. The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46*. J. Biol. Chem. 2010, 285:22075-22081.
11. Urbina J.A. Ergosterol biosynthesis and drug development for Chagas disease. Mem. Inst. Oswaldo Cruz. 2009, 104(Suppl. 1):311-318.
12. Sanchez-Sancho F., Campillo N.E., Paez J.A. Chagas disease: progress and new perspectives. Curr. Med. Chem. 2010, 17:423-452.
13. Hellmuth K., Grosskopf S., Lum C.T., Wurtele M., Roder N., von Kries J.P., Rosario M., Rademann J., Birchmeier W. Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking. Proc. Natl. Acad. Sci. USA 2008, 105:7275-7280.
14. Psakis G., Nitschkowski S., Holz C., Kress D., Maestre-Reyna M., Polaczek J., Illing G., Essen L.O. Expression screening of integral membrane proteins from Helicobacter pylori 26695. Protein Sci. 2007, 16:2667-2676.
15. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
16. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
17. Contreras V.T., Araujo-Jorge T.C., Bonaldo M.C., Thomaz N., Barbosa H.S., Meirelles Mde N., Goldenberg S. Biological aspects of the Dm 28c clone of Trypanosoma cruzi after metacyclogenesis in chemically defined media. Mem. Inst. Oswaldo Cruz. 1988, 83:123-133.
18. Contreras V.T., Salles J.M., Thomas N., Morel C.M., Goldenberg S. In vitro differentiation of Trypanosoma cruzi under chemically defined conditions. Mol. Biochem. Parasitol. 1985, 16:315-327.
19. Sakdapipanich J.T. Structural characterization of natural rubber based on recent evidence from selective enzymatic treatments. J. Biosci. Bioeng. 2007, 103:287-292.
20. Nascimento M., Zhang W.W., Ghosh A., Houston D.R., Berghuis A.M., Olivier M., Matlashewski G. Identification and characterization of a protein-tyrosine phosphatase in Leishmania: involvement in virulence. J. Biol. Chem. 2006, 281:36257-36268.
21. Sarmiento M., Zhao Y., Gordon S.J., Zhang Z.Y. Molecular basis for substrate specificity of protein-tyrosine phosphatase 1B. J. Biol. Chem. 1998, 273:26368-26374.
22. Wiesmann C., Barr K.J., Kung J., Zhu J., Erlanson D.A., Shen W., Fahr B.J., Zhong M., Taylor L., Randal M., McDowell R.S., Hansen S.K. Allosteric inhibition of protein tyrosine phosphatase 1B. Nat. Struct. Mol. Biol. 2004, 11:730-737.
23. Shrestha S., Bhattarai B.R., Cho H., Choi J.K., Cho H. PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IkappaB kinase beta (IKK-beta). Bioorg. Med. Chem. Lett. 2007, 17:2728-2730.
24. Zhong L., Lu H.G., Moreno S.N., Docampo R. Tyrosine phosphate hydrolysis of host proteins by Trypanosoma cruzi is linked to cell invasion. FEMS Microbiol. Lett. 1998, 161:15-20.
25. Butler D. Parasitology: triple genome triumph. Nature 2005, 436:337.
26. N.M. El-Sayed, P.J. Myler, D.C. Bartholomeu, D. Nilsson, G. Aggarwal, A.N. Tran, E. Ghedin, E.A. Worthey, A.L. Delcher, G. Blandin, S.J. Westenberger, E. Caler, G.C. Cerqueira, C. Branche, B. Haas, A. Anupama, E. Arner, L. Aslund, P. Attipoe, E. Bontempi, F. Bringaud, P. Burton, E. Cadag, D.A. Campbell, M. Carrington, J. Crabtree, H. Darban, J.F. da Silveira, P. de Jong, K. Edwards, P.T. Englund, G. Fazelina, T. Feldblyum, M. Ferella, A.C. Frasch, K. Gull, D. Horn, L. Hou, Y. Huang, E. Kindlund, M. Klingbeil, S. Kluge, H. Koo, D. Lacerda, M.J. Levin, H. Lorenzi, T. Louie, C.R. Machado, R. McCulloch, A. McKenna, Y. Mizuno, J.C. Mottram, S. Nelson, S. Ochaya, K. Osoegawa, G. Pai, M. Parsons, M. Pentony, U. Pettersson, M. Pop, J.L. Ramirez, J. Rinta, L. Robertson, S.L. Salzberg, D.O. Sanchez, A. Seyler, R. Sharma, J. Shetty, A.J. Simpson, E. Sisk, M.T. Tammi, R. Tarleton, S. Teixeira, S. Van Aken, C. Vogt, P.N. Ward, B. Wickstead, J. Wortman, O. White, C.M. Fraser, K.D. Stuart, B. Andersson, The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease, Science 309 (2005) 409-415.
27. M. Berriman, E. Ghedin, C. Hertz-Fowler, G. Blandin, H. Renauld, D.C. Bartholomeu, N.J. Lennard, E. Caler, N.E. Hamlin, B. Haas, U. Bohme, L. Hannick, M.A. Aslett, J. Shallom, L. Marcello, L. Hou, B. Wickstead, U.C. Alsmark, C. Arrowsmith, R.J. Atkin, A.J. Barron, F. Bringaud, K. Brooks, M. Carrington, I. Cherevach, T.J. Chillingworth, C. Churcher, L.N. Clark, C.H. Corton, A. Cronin, R.M. Davies, J. Doggett, A. Djikeng, T. Feldblyum, M.C. Field, A. Fraser, I. Goodhead, Z. Hance, D. Harper, B.R. Harris, H. Hauser, J. Hostetler, A. Ivens, K. Jagels, D. Johnson, J. Johnson, K. Jones, A.X. Kerhornou, H. Koo, N. Larke, S. Landfear, C. Larkin, V. Leech, A. Line, A. Lord, A. Macleod, P.J. Mooney, S. Moule, D.M. Martin, G.W. Morgan, K. Mungall, H. Norbertczak, D. Ormond, G. Pai, C.S. Peacock, J. Peterson, M.A. Quail, E. Rabbinowitsch, M.A. Rajandream, C. Reitter, S.L. Salzberg, M. Sanders, S. Schobel, S. Sharp, M. Simmonds, A.J. Simpson, L. Tallon, C.M. Turner, A. Tait, A.R. Tivey, S. Van Aken, D. Walker, D. Wanless, S. Wang, B. White, O. White, S. Whitehead, J. Woodward, J. Wortman, M.D. Adams, T.M. Embley, K. Gull, E. Ullu, J.D. Barry, A.H. Fairlamb, F. Opperdoes, B.G. Barrell, J.E. Donelson, N. Hall, C.M. Fraser, S.E. Melville, N.M. El-Sayed, The genome of the African trypanosome Trypanosoma brucei, Science 309 (2005) 416-422.
28. Jackson A.P., Sanders M., Berry A., McQuillan J., Aslett M.A., Quail M.A., Chukualim B., Capewell P., MacLeod A., Melville S.E., Gibson W., Barry J.D., Berriman M., Hertz-Fowler C. The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis. PLoS Negl. Trop. Dis. 2010, 4:e658.
29. A.C. Ivens, C.S. Peacock, E.A. Worthey, L. Murphy, G. Aggarwal, M. Berriman, E. Sisk, M.A. Rajandream, E. Adlem, R. Aert, A. Anupama, Z. Apostolou, P. Attipoe, N. Bason, C. Bauser, A. Beck, S.M. Beverley, G. Bianchettin, K. Borzym, G. Bothe, C.V. Bruschi, M. Collins, E. Cadag, L. Ciarloni, C. Clayton, R.M. Coulson, A. Cronin, A.K. Cruz, R.M. Davies, J. De Gaudenzi, D.E. Dobson, A. Duesterhoeft, G. Fazelina, N. Fosker, A.C. Frasch, A. Fraser, M. Fuchs, C. Gabel, A. Goble, A. Goffeau, D. Harris, C. Hertz-Fowler, H. Hilbert, D. Horn, Y. Huang, S. Klages, A. Knights, M. Kube, N. Larke, L. Litvin, A. Lord, T. Louie, M. Marra, D. Masuy, K. Matthews, S. Michaeli, J.C. Mottram, S. Muller-Auer, H. Munden, S. Nelson, H. Norbertczak, K. Oliver, S. O'Neil, M. Pentony, T.M. Pohl, C. Price, B. Purnelle, M.A. Quail, E. Rabbinowitsch, R. Reinhardt, M. Rieger, J. Rinta, J. Robben, L. Robertson, J.C. Ruiz, S. Rutter, D. Saunders, M. Schafer, J. Schein, D.C. Schwartz, K. Seeger, A. Seyler, S. Sharp, H. Shin, D. Sivam, R. Squares, S. Squares, V. Tosato, C. Vogt, G. Volckaert, R. Wambutt, T. Warren, H. Wedler, J. Woodward, S. Zhou, W. Zimmermann, D.F. Smith, J.M. Blackwell, K.D. Stuart, B. Barrell, P.J. Myler
30. Parsons M., Valentine M., Deans J., Schieven G.L., Ledbetter J.A. Distinct patterns of tyrosine phosphorylation during the life cycle of Trypanosoma brucei. Mol. Biochem. Parasitol. 1991, 45:241-248.
31. Dell K.R., Engel J.N. Stage-specific regulation of protein phosphorylation in Leishmania major. Mol. Biochem. Parasitol. 1994, 64:283-292.
32. Larkin M.A., Blackshields G., Brown N.P., Chenna R., McGettigan P.A., McWilliam H., Valentin F., Wallace I.M., Wilm A., Lopez R., Thompson J.D., Gibson T.J., Higgins D.G. Clustal W and Clustal X version 2.0. Bioinformatics 2007, 23:2947-2948.