αA-crystallin peptide 66SDRDKFVIFLDVKHF80 accumulating in aging lens impairs the function of α-crystallin and induces lens protein aggregation

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Santhoshkumar, Puttur ^a   Raju, Murugesan ^a   Sharma, K Krishna ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA A CRYSTALLIN[66-80]; ALPHA CRYSTALLIN; AMYLOID BETA PROTEIN; BETA CRYSTALLIN; CHAPERONE; GAMMA CRYSTALLIN; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT;

AGING; AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; BIOACCUMULATION; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; HUMAN; HUMAN TISSUE; HYDROPHOBICITY; LENS; LIGHT SCATTERING; MASS SPECTROMETRY; MULTI ANGLE LIGHT SCATTERING; PRECIPITATION; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SOLUBILITY; CATARACT; CHEMICAL PHENOMENA; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; MOLECULAR WEIGHT; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE;

AGING; ALPHA-CRYSTALLIN A CHAIN; AMINO ACID SEQUENCE; CATARACT; CHEMICAL PRECIPITATION; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LENS, CRYSTALLINE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SOLUBILITY;

EID: 79955709128     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019291     Document Type: Article

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