Folate-conjugated amphiphilic star-shaped block copolymers as targeted nanocarriers

Journal of Biomedical Materials Research - Part A

Volumn 97 A, Issue 4, 2011, Pages 498-508

  Zhu, Jundong ^a   Zhou, Zhichao ^a   Yang, Cuihong ^b   Kong, Deling ^b   Wan, Ying ^c   Wang, Zheng ^a  

^a TIANJIN UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

intracellular uptake; polymeric micelle; stability; star shaped copolymer; targeted carrier

Indexed keywords

AMPHIPHILICS; ANTI-CANCER DRUG DELIVERY; AVERAGE SIZE; CANCER CELLS; CERVICAL CANCER CELLS; CRITICAL MICELLE CONCENTRATION (CMC); FLUORESCENCE MICROSCOPES; IN-VITRO; INDOMETHACIN; INTRACELLULAR UPTAKE; L-LACTIDE; METHOXY POLY(ETHYLENE GLYCOL); MODEL DRUGS; NANOCARRIERS; POLY L LACTIC ACID; POLYMERIC MICELLE; STAR-SHAPED BLOCK COPOLYMERS; STAR-SHAPED COPOLYMER; SUSTAINED RELEASE; TARGETED CARRIER;

BLOCK COPOLYMERS; BODY FLUIDS; CELLS; COPOLYMERIZATION; CRITICAL MICELLE CONCENTRATION; DISEASES; DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; FLOW CYTOMETRY; LACTIC ACID; MICELLES; MOTION PICTURE EXPERTS GROUP STANDARDS; ORGANIC POLYMERS; PLASTIC PRODUCTS; POLYETHYLENE OXIDES; POLYMERS; RING OPENING POLYMERIZATION; STARS;

POLYETHYLENE GLYCOLS;

COPOLYMER; FOLATE RECEPTOR; FOLIC ACID; FOLIC ACID POLYLACTIC ACID; INDOMETACIN; MACROGOL; METHOXY POLY(ETHYLENE GLYCOL); NANOCARRIER; PENTAERYTHRITOL; POLYLACTIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DEGRADATION; DRUG RELEASE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MICELLE; PARTICLE SIZE; SUSTAINED DRUG RELEASE; SYNTHESIS;

COUMARINS; DRUG CARRIERS; FLUORESCENCE; FOLIC ACID; HELA CELLS; HUMANS; INDOMETHACIN; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; MOLECULAR WEIGHT; NANOSTRUCTURES; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; PROPYLENE GLYCOLS; SURFACE-ACTIVE AGENTS; THIAZOLES;

EID: 79955669406     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33071     Document Type: Article

References (31)

1. Lim DW, Park TG,. Stereocomplex formation between enantiomeric PLA-PEG-PLA triblock copolymers: Characterization and use as protein-delivery microparticulate carriers. J Appl Polym Sci 2007; 73: 1615-1623.
2. Xie ZG, Lu TC, Chen XS, Zheng YH, Jing XB,. Synthesis, self-assembly in water, and cytotoxicity of MPEG-block-PLLA/DX conjugates. J Biomed Mater Res A 2009; 88: 238-245.
3. Gao XL, Tao WX, Lu W, Zhang QZ, Zhang Y, Jiang XG, Fu SK,. Lectin-conjugated PEG-PLA nanoparticles: Preparation and brain delivery after intranasal administration. Biomaterials 2006; 27: 3482-3490.
4. Sankaran NB, Rys AZ, Nassif R, Nayak MK, Metera K, Chen BZ, Bazzi HS, Sleiman HF,. Ring-opening metathesis polymers for biodetection and signal amplification: Synthesis and self-assembly. Macromolecules 2010; 43: 5530-5537.
5. Kwon GS, Okano T,. Polymeric micelles as new drug carriers. Adv Drug Deliv Rev 1996; 21: 107-116. (Pubitemid 26401713)
6. Wilhelm M, Zhao C, Wang Y, Xu R, Winnik MA, Mura J, Reiss G, Croucher MD,. Poly(styrene-ethyleneoxide) block copolymer micelle formation in water: A fluorescence probe study. Macromolecules 1991; 24: 1033-1040.
7. Kwon GS, Naito M, Yokoyama M, Okano T, Sakurai Y, Kataoka K,. Micelles based on AB block copolymers of poly(ethylene oxide) and poly(β-benzyl L -aspartate). Langmuir 1993; 9: 945-949.
8. Avgoustakis K, Beletsi A, Panagi Z, Klepetsanis P, Livaniou E, Evangelatos G, Ithakissios DS,. Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA-mPEG nanoparticles. Int J Pharm 2003; 259: 115-127. (Pubitemid 36638559)
9. He GS, Ma LL, Pan J, Venkatraman S,. ABA and BAB type triblock copolymers of PEG and PLA: A comparative study of drug release properties and "stealth" particle characteristics. Int J Pharm 2007; 334: 48-55. (Pubitemid 46400312)
10. Shen CH, Guo SR, Lul CF,. Degradation behaviors of monomethoxy poly(ethylene glycol)-b-poly(epsilon-caprolactone) nanoparticles in aqueous solution. Polym Adv Technol 2008; 19: 66-72.
11. Lawrence MJ,. Surfactant systems: their use in drug delivery. Chem Soc Rev 1994; 23: 417-424. (Pubitemid 24986161)
12. Wang F, Bronich TK, Kabanov AV, Rauh RD, Roovers J,. Synthesis and evaluation of a star amphiphilic block copolymer from poly(Îμ- caprolactone) and poly(ethylene glycol) as a potential drug delivery carrier. Bioconjug Chem 2005; 16: 397-405. (Pubitemid 40388216)
13. Wang F, Bronich TK, Kabanov AV, Rauh RD, Roovers J,. Synthesis and characterization of star poly(Îμ-caprolactone)-b-poly(ethylene glycol) and poly(L -lactide)-b-poly(ethylene glycol) copolymers: Evaluation as drug delivery carriers. Bioconjug Chem 2008; 19: 1423-1429. (Pubitemid 352032342)
14. Kim KH, Cui GH, Lim HJ, Huh J, Ahn CH, Jo WH,. Synthesis and micellization of star-shaped poly(ethylene glycol)-block-poly(Îμ- caprolactone). Macromol Chem Phys 2004; 205: 1684-1692.
15. Han X, Liu J, Liu M,. 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: Preparation and evaluation in vitro. Int J Pharm 2009; 372: 125-131.
16. Jain KK,. Targeted drug delivery for cancer. Tech Canc Res Treat 2005; 4: 311-313.
17. Stella B, Arpicco S, Peracchia MT, Couvreur P,. Design of folic acid-conjugated nanoparticles for drug targrting. J Pharm Sci 2000; 89: 1452-1464.
18. Reddy JA, Low PS,. Folate-mediated targeting of therapeutic and imaging agents to cancers. Crit Rev Ther Drug Carrier Syst 1998; 15: 587-627. (Pubitemid 29006581)
19. AH40, poly(L -lactide) and poly(ethylene glycol) for tumor-targeted drug delivery. Biomaterials 2009; 30: 3009-3019.
20. Singh P, Gupta U, Asthana A, Jain NK,. Folate and folate-PEG-PAMAM dendrimers: Synthesis, characterization, and targeted anticancer drug delivery potential in tumor bearing mice. Bioconjugate Chem 2008; 19: 2239-2252.
21. Furukawa S, Katayama N, Iizuka T,. Preparation of polyethylene glycol-bound and its application in a model enzyme reactor. FEBS Lett 1980; 121: 239-242.
22. George KA, Schué F, Chirila TV, Wentrup-byrne E,. Synthesis of four-arm star poly(L -lactide) oligomers using an in situ-generated calcium-based initiator. J Polym Sci Part A Polym Chem 2009; 47: 4736-4748.
23. Yoo HS, Lee EA, Park TG,. Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. J Control Rel 2002; 82: 17-27. (Pubitemid 34775044)
24. Gabizon A, Horowitz AT, Goren D, Tzemach D, Shmeeda H, Zalipsky S,. In vivo fate of folate-targeted polyethylene-glycol liposomes in tumor-bearing mice. Clin Cancer Res 2003; 9: 6551-6559. (Pubitemid 38031844)
25. Schmalenberg KE, Frauchiger L, Nikkhouy-Albers L, Uhrich KE,. Cytotoxocity of a unimolecular polymeric micelle and its degradation products. Biomacromolecules 2001; 2: 851-855. (Pubitemid 32894642)
26. Ciuchi F, Nicola GD, Franz H, Gottarelli G, Mariani P, Bossi MGP, Spada GP,. Selfrecognition and self-assembly of folic acids salts: Columnar liquid crystalline polymorphism and the columns growth process. J Am Chem Soc 1994; 116: 7064-7071. (Pubitemid 24981401)
27. Kalyanasundaram K, Thomas JK,. Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems. J Am Chem Soc 1977; 99: 2039-2044.
28. Yuan F, Dellian M, Fukumura D, Leunig M, Berk DA, Torchilin VP, Jain RK,. Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size. Cancer Res 1995; 55: 3752-3756.
29. Jiang Z, You Y, Deng X, Hao J,. Injectable hydrogels of poly(Îμ-caprolactone-coglycolide)-poly(ethyleneglycol) -poly(Îμ-caprolactone-co-glycolide) triblock copolymer aqueous solutions. Polymer 2007; 48: 4786-4792. (Pubitemid 47069494)
30. Leamon CP, Low PS,. Delivery of macromolecules into living cellsâA method that exploits folate receptor endocytosis. Proc Natl Acad Sci 1991; 88: 5572-5576. (Pubitemid 21914787)
31. Yoo HS, Park TG,. Folate-receptor-targeted delivery of doxorubicin nanoaggregates stabilized by doxorubicine-PEG-folate conjugate. J Control Rel 2004; 100: 247-56. (Pubitemid 39491276)