Regulation of IGF-1-dependent cyclin D1 and E expression by hEag1 channels in MCF-7 cells: The critical role of hEag1 channels in G1 phase progression

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1813, Issue 5, 2011, Pages 723-730

  Borowiec, Anne Sophie ^a   Hague, Frédéric ^a   Gouilleux Gruart, Valérie ^b   Lassoued, Kaiss ^c   Ouadid Ahidouch, Halima ^a  

^a Université Picardie Jules Vernes   (France)

^b CNRS   (France)

^c UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

Author keywords

Cell cycle; Cyclin expression regulation; G1 S transition; HEag1; IGF 1

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ASTEMIZOLE; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; POTASSIUM CHANNEL; POTASSIUM HEAG1; SMALL INTERFERING RNA; SOMATOMEDIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER GROWTH; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ASTEMIZOLE; CELL LINE, TUMOR; CYCLIN D1; CYCLIN E; ETHER-A-GO-GO POTASSIUM CHANNELS; G1 PHASE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; ION CHANNEL GATING; ONCOGENE PROTEINS; POTASSIUM CHANNEL BLOCKERS; S PHASE; TIME FACTORS; UP-REGULATION;

EID: 79955668081     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.01.025     Document Type: Article

References (50)

1. Ouadid-Ahidouch H., Ahidouch A. K+ channel expression in human breast cancer cells: involvement in cell cycle regulation and carcinogenesis. J. Membr. Biol. 2008, 221:1-6.
2. Wang Z. Roles of K+ channels in regulating tumour cell proliferation and apoptosis. Pflugers Arch. 2004, 448:274-286.
3. Wulff H., Castle N.A., Pardo L.A. Voltage-gated potassium channels as therapeutic targets. Nat. Rev. Drug Discov. 2009, 8:982-1001.
4. Pardo L.A., Contreras-Jurado C., Zientkowska M., Alves F., Stuhmer W. Role of voltage-gated potassium channels in cancer. J. Membr. Biol. 2005, 205:115-124.
5. Pardo L.A., Suhmer W. Eag1 as a cancer target. Expert Opin. Ther. Targets 2008, 12:837-843.
6. Hemmerlein B., Weseloh R.M., Mello de Queiroz F., Knotgen H., Sanchez A., Rubio M.E., Martin S., Schliephacke T., Jenke M., Heinz Joachim R., Stuhmer W., Pardo L.A. Overexpression of Eag1 potassium channels in clinical tumours. Mol. Cancer 2006, 5:41.
7. Mello de Queiroz F., Suarez-Kurtz G., Stuhmer W., Pardo L.A. Ether a go-go potassium channel expression in soft tissue sarcoma patients. Mol. Cancer 2006, 5:42.
8. Ouadid-Ahidouch H., Le Bourhis X., Roudbaraki M., Toillon R.A., Delcourt P., Prevarskaya N. Changes in the K+ current-density of MCF-7 cells during progression through the cell cycle: possible involvement of a h-ether.a-gogo K+ channel. Recept. Channels 2001, 7:345-356.
9. Ouadid-Ahidouch H., Roudbaraki M., Delcourt P., Ahidouch A., Joury N., Prevarskaya N. Functional and molecular identification of intermediate-conductance Ca(2+)-activated K(+) channels in breast cancer cells: association with cell cycle progression. Am. J. Physiol. Cell Physiol. 2004, 287:C125-C134.
10. Ghiani C.A., Yuan X., Eisen A.M., Knutson P.L., DePinho R.A., McBain C.J., Gallo V. Voltage-activated K+ channels and membrane depolarization regulate accumulation of the cyclin-dependent kinase inhibitors p27(Kip1) and p21(CIP1) in glial progenitor cells. J. Neurosci. 1999, 19:5380-5392.
11. Wonderlin W.F., Strobl J.S. Potassium channels, proliferation and G1 progression. J. Membr. Biol. 1996, 154:91-107.
12. Pestell R.G., Albanese C., Reutens A.T., Segall J.E., Lee R.J., Arnold A. The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocr. Rev. 1999, 20:501-534.
13. Bartkova J., Lukas J., Muller H., Lutzhoft D., Strauss M., Bartek J. Cyclin D1 protein expression and function in human breast cancer. Int. J. Cancer 1994, 57:353-361.
14. Zwijsen R.M., Klompmaker R., Wientjens E.B., Kristel P.M., van der Burg B., Michalides R.J. Cyclin D1 triggers autonomous growth of breast cancer cells by governing cell cycle exit. Mol. Cell. Biol. 1996, 16:2554-2560.
15. Grillo M., Bott M.J., Khandke N., McGinnis J.P., Miranda M., Meyyappan M., Rosfjord E.C., Rabindran S.K. Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression. Breast Cancer Res. Treat. 2006, 95:185-194.
16. Alle K.M., Henshall S.M., Field A.S., Sutherland R.L. Cyclin D1 protein is overexpressed in hyperplasia and intraductal carcinoma of the breast. Clin. Cancer Res. 1998, 4:847-854.
17. Buckley M.F., Sweeney K.J., Hamilton J.A., Sini R.L., Manning D.L., Nicholson R.I., deFazio A., Watts C.K., Musgrove E.A., Sutherland R.L. Expression and amplification of cyclin genes in human breast cancer. Oncogene 1993, 8:2127-2133.
18. Keyomarsi K., O'Leary N., Molnar G., Lees E., Fingert H.J., Pardee A.B. Cyclin E, a potential prognostic marker for breast cancer. Cancer Res. 1994, 54:380-385.
19. Lindahl T., Landberg G., Ahlgren J., Nordgren H., Norberg T., Klaar S., Holmberg L., Bergh J. Overexpression of cyclin E protein is associated with specific mutation types in the p53 gene and poor survival in human breast cancer. Carcinogenesis 2004, 25:375-380.
20. Macaulay V.M. Insulin-like growth factors and cancer. Br. J. Cancer 1992, 65:311-320.
21. Oku K., Tanaka A., Yamanishi H., Nishizawa Y., Matsumoto K., Shiozaki H., Mori T. Effects of various growth factors on growth of a cloned human esophageal squamous cancer cell line in a protein-free medium. Anticancer Res. 1991, 11:1591-1595.
22. Dufourny B., Alblas J., van Teeffelen H.A., van Schaik F.M., van der Burg B., Steenbergh P.H., Sussenbach J.S. Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J. Biol. Chem. 1997, 272:31163-31171.
23. Borowiec A.S., Hague F., Harir N., Guenin S., Guerineau F., Gouilleux F., Roudbaraki M., Lassoued K., Ouadid-Ahidouch H. IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation. J. Cell. Physiol. 2007, 212:690-701.
24. Weber C., Mello de Queiroz F., Downie B.R., Suckow A., Stuhmer W., Pardo L.A. Silencing the activity and proliferative properties of the human EagI potassium channel by RNA interference. J. Biol. Chem. 2006, 281:13030-13037.
25. Gresch O., Engel F.B., Nesic D., Tran T.T., England H.M., Hickman E.S., Korner I., Gan L., Chen S., Castro-Obregon S., Hammermann R., Wolf J., Muller-Hartmann H., Nix M., Siebenkotten G., Kraus G., Lun K. New non-viral method for gene transfer into primary cells. Methods 2004, 33:151-163.
26. Chen Y.Y., Rabinovitch P.S. Altered cell cycle responses to insulin-like growth factor I, but not platelet-derived growth factor and epidermal growth factor, in senescing human fibroblasts. J. Cell. Physiol. 1990, 144:18-25.
27. Roy J., Vantol B., Cowley E.A., Blay J., Linsdell P. Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7. Oncol. Rep. 2008, 19:1511-1516.
28. Suessbrich H., Waldegger S., Lang F., Busch A.E. Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole. FEBS Lett. 1996, 385:77-80.
29. Garcia-Ferreiro R.E., Kerschensteiner D., Major F., Monje F., Stuhmer W., Pardo L.A. Mechanism of block of hEag1 K+ channels by imipramine and astemizole. J. Gen. Physiol. 2004, 124:301-317.
30. Jakobisiak M., Bruno S., Skierski J.S., Darzynkiewicz Z. Cell cycle-specific effects of lovastatin. Proc. Natl Acad. Sci. U. S. A. 1991, 88:3628-3632.
31. Keyomarsi K., Sandoval L., Band V., Pardee A.B. Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin. Cancer Res. 1991, 51:3602-3609.
32. Dupont J., Karas M., LeRoith D. The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells. J. Biol. Chem. 2003, 278:37256-37264.
33. Lai A., Sarcevic B., Prall O.W., Sutherland R.L. Insulin/insulin-like growth factor-I and estrogen cooperate to stimulate cyclin E-Cdk2 activation and cell cycle progression in MCF-7 breast cancer cells through differential regulation of cyclin E and p21(WAF1/Cip1). J. Biol. Chem. 2001, 276:25823-25833.
34. LaBaer J., Garrett M.D., Stevenson L.F., Slingerland J.M., Sandhu C., Chou H.S., Fattaey A., Harlow E. New functional activities for the p21 family of CDK inhibitors. Genes Dev. 1997, 11:847-862.
35. Musgrove E.A., Hamilton J.A., Lee C.S., Sweeney K.J., Watts C.K., Sutherland R.L. Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Mol. Cell. Biol. 1993, 13:3577-3587.
36. Liu J.J., Chao J.R., Jiang M.C., Ng S.Y., Yen J.J., Yang-Yen H.F. Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells. Mol. Cell. Biol. 1995, 15:3654-3663.
37. Dufourny B., van Teeffelen H.A., Hamelers I.H., Sussenbach J.S., Steenbergh P.H. Stabilization of cyclin D1 mRNA via the phosphatidylinositol 3-kinase pathway in MCF-7 human breast cancer cells. J. Endocrinol. 2000, 166:329-338.
38. Chittajallu R., Chen Y., Wang H., Yuan X., Ghiani C.A., Heckman T., McBain C.J., Gallo V. Regulation of Kv1 subunit expression in oligodendrocyte progenitor cells and their role in G1/S phase progression of the cell cycle. Proc. Natl Acad. Sci. U. S. A. 2002, 99:2350-2355.
39. Renaudo A., L'Hoste S., Guizouarn H., Borgese F., Soriani O. Cancer cell cycle modulated by a functional coupling between sigma-1 receptors and Cl- channels. J. Biol. Chem. 2007, 282:2259-2267.
40. Renaudo A., Watry V., Chassot A.A., Ponzio G., Ehrenfeld J., Soriani O. Inhibition of tumor cell proliferation by sigma ligands is associated with K+ Channel inhibition and p27kip1 accumulation. J. Pharmacol. Exp. Ther. 2004, 311:1105-1114.
41. Kunzelmann K. Ion channels and cancer. J. Membr. Biol. 2005, 205:159-173.
42. Calautti E., Li J., Saoncella S., Brissette J.L., Goetinck P.F. Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death. J. Biol. Chem. 2005, 280:32856-32865.
43. Lotti L.V., Rotolo S., Francescangeli F., Frati L., Torrisi M.R., Marchese C. AKT and MAPK signaling in KGF-treated and UVB-exposed human epidermal cells. J. Cell. Physiol. 2007, 212:633-642.
44. Cook S.J., Lockyer P.J. Recent advances in Ca(2+)-dependent Ras regulation and cell proliferation. Cell Calcium 2006, 39:101-112.
45. Resende R.R., Adhikari A., da Costa J.L., Lorencon E., Ladeira M.S., Guatimosim S., Kihara A.H., Ladeira L.O. Influence of spontaneous calcium events on cell-cycle progression in embryonal carcinoma and adult stem cells. Biochim. Biophys. Acta 2010, 1803:246-260.
46. El Boustany C., Katsogiannou M., Delcourt P., Dewailly E., Prevarskaya N., Borowiec A.S., Capiod T. Differential roles of STIM1, STIM2 and Orai1 in the control of cell proliferation and SOCE amplitude in HEK293 cells. Cell Calcium 2010, 47:350-359.
47. Guilbert A., Dhennin-Duthille I., Hiani Y.E., Haren N., Khorsi H., Sevestre H., Ahidouch A., Ouadid-Ahidouch H. Expression of TRPC6 channels in human epithelial breast cancer cells. BMC Cancer 2008, 8:125.
48. Kahl C.R., Means A.R. Regulation of cell cycle progression by calcium/calmodulin-dependent pathways. Endocr. Rev. 2003, 24:719-736.
49. Yao X., Kwan H.Y. Activity of voltage-gated K+ channels is associated with cell proliferation and Ca2+ influx in carcinoma cells of colon cancer. Life Sci. 1999, 65:55-62.
50. Zhanping W., Xiaoyu P., Na C., Shenglan W., Bo W. Voltage-gated K+ channels are associated with cell proliferation and cell cycle of ovarian cancer cell. Gynecol. Oncol. 2007, 104:455-460.