메뉴 건너뛰기




Volumn 202, Issue 2, 2011, Pages 185-192

Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel

Author keywords

Flavonoids; Neuroprotective agents; Potassium channels; Riluzole

Indexed keywords

BAICALEIN; FLAVONOID; POTASSIUM CHANNEL; RILUZOLE; TREK 1 PROTEIN; TREK 2 PROTEIN; UNCLASSIFIED DRUG; WOGONIN;

EID: 79955658804     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2011.02263.x     Document Type: Article
Times cited : (19)

References (47)
  • 1
    • 59249086196 scopus 로고    scopus 로고
    • Mechanisms of flavonoid protection against myocardial ischemia-reperfusion injury
    • Akhlaghi, M. & Bandy, B. 2009. Mechanisms of flavonoid protection against myocardial ischemia-reperfusion injury. J Mol Cell Cardiol 46, 309-317.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 309-317
    • Akhlaghi, M.1    Bandy, B.2
  • 3
    • 71849100827 scopus 로고    scopus 로고
    • Genistein and daidzein prevent low potassium-dependent apoptosis of cerebellar granule cells
    • Atlante, A., Bobba, A., Paventi, G., Pizzuto, R. & Passarella, S. 2010. Genistein and daidzein prevent low potassium-dependent apoptosis of cerebellar granule cells. Biochem Pharmacol 79, 758-767.
    • (2010) Biochem Pharmacol , vol.79 , pp. 758-767
    • Atlante, A.1    Bobba, A.2    Paventi, G.3    Pizzuto, R.4    Passarella, S.5
  • 5
    • 0030250416 scopus 로고    scopus 로고
    • Volume-sensitive chloride channels blocked by neuroprotective drugs in human glial cells (U-138MG)
    • Bausch, A.R. & Roy, G. 1996. Volume-sensitive chloride channels blocked by neuroprotective drugs in human glial cells (U-138MG). Glia 18, 73-77.
    • (1996) Glia , vol.18 , pp. 73-77
    • Bausch, A.R.1    Roy, G.2
  • 6
    • 50449111165 scopus 로고    scopus 로고
    • Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity
    • Benavente-Garcia, O. & Castillo, J. 2008. Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity. J Agric Food Chem 56, 6185-6205.
    • (2008) J Agric Food Chem , vol.56 , pp. 6185-6205
    • Benavente-Garcia, O.1    Castillo, J.2
  • 8
    • 46149119392 scopus 로고    scopus 로고
    • Neuroprotective effect of baicalein against MPTP neurotoxicity: behavioral, biochemical and immunohistochemical profile
    • Cheng, Y., He, G., Mu, X., Zhang, T., Li, X., Hu, J., Xu, B. & Du, G. 2008. Neuroprotective effect of baicalein against MPTP neurotoxicity: behavioral, biochemical and immunohistochemical profile. Neurosci Lett 441, 16-20.
    • (2008) Neurosci Lett , vol.441 , pp. 16-20
    • Cheng, Y.1    He, G.2    Mu, X.3    Zhang, T.4    Li, X.5    Hu, J.6    Xu, B.7    Du, G.8
  • 9
    • 1642497587 scopus 로고    scopus 로고
    • Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells
    • Cho, J. & Lee, H.K. 2004a. Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells. Eur J Pharmacol 485, 105-110.
    • (2004) Eur J Pharmacol , vol.485 , pp. 105-110
    • Cho, J.1    Lee, H.K.2
  • 10
    • 21644489720 scopus 로고    scopus 로고
    • Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion
    • Cho, J. & Lee, H.K. 2004b. Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. Biol Pharm Bull 27, 1561-1564.
    • (2004) Biol Pharm Bull , vol.27 , pp. 1561-1564
    • Cho, J.1    Lee, H.K.2
  • 11
    • 0344851906 scopus 로고    scopus 로고
    • The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia
    • Chou, T.C., Chang, L.P., Li, C.Y., Wong, C.S. & Yang, S.P. 2003. The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Anesth Analg 97, 1724-1729.
    • (2003) Anesth Analg , vol.97 , pp. 1724-1729
    • Chou, T.C.1    Chang, L.P.2    Li, C.Y.3    Wong, C.S.4    Yang, S.P.5
  • 13
    • 67650432133 scopus 로고    scopus 로고
    • Neuroprotection: extrapolating from neurologic diseases to the eye
    • Danesh-Meyer, H.V. & Levin, L.A. 2009. Neuroprotection: extrapolating from neurologic diseases to the eye. Am J Ophthalmol 148, 186-191. e182.
    • (2009) Am J Ophthalmol 148 , vol.186-191
    • Danesh-Meyer, H.V.1    Levin, L.A.2
  • 14
    • 0027213025 scopus 로고
    • Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes
    • Debono, M.W., Le Guern, J., Canton, T., Doble, A. & Pradier, L. 1993. Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes. Eur J Pharmacol 235, 283-289.
    • (1993) Eur J Pharmacol , vol.235 , pp. 283-289
    • Debono, M.W.1    Le Guern, J.2    Canton, T.3    Doble, A.4    Pradier, L.5
  • 15
    • 0029753270 scopus 로고    scopus 로고
    • The pharmacology and mechanism of action of riluzole
    • Doble, A. 1996. The pharmacology and mechanism of action of riluzole. Neurology 47, S233-241.
    • (1996) Neurology , vol.47
    • Doble, A.1
  • 18
    • 77954861154 scopus 로고    scopus 로고
    • Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple
    • Feng, J., Xu, W., Tao, X., Wei, H., Cai, F., Jiang, B. & Chen, W. 2010. Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple. J Pharm Biomed Anal 53, 591-598.
    • (2010) J Pharm Biomed Anal , vol.53 , pp. 591-598
    • Feng, J.1    Xu, W.2    Tao, X.3    Wei, H.4    Cai, F.5    Jiang, B.6    Chen, W.7
  • 19
    • 0032750323 scopus 로고    scopus 로고
    • Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi
    • Gao, Z., Huang, K., Yang, X. & Xu, H. 1999. Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Biochim Biophys Acta 1472, 643-650.
    • (1999) Biochim Biophys Acta , vol.1472 , pp. 643-650
    • Gao, Z.1    Huang, K.2    Yang, X.3    Xu, H.4
  • 20
    • 0034950875 scopus 로고    scopus 로고
    • Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells
    • Gao, Z., Huang, K. & Xu, H. 2001. Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells. Pharmacol Res 43, 173-178.
    • (2001) Pharmacol Res , vol.43 , pp. 173-178
    • Gao, Z.1    Huang, K.2    Xu, H.3
  • 23
    • 29744459904 scopus 로고    scopus 로고
    • Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia
    • Heurteaux, C., Laigle, C., Blondeau, N., Jarretou, G. & Lazdunski, M. 2006. Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia. Neuroscience 137, 241-251.
    • (2006) Neuroscience , vol.137 , pp. 241-251
    • Heurteaux, C.1    Laigle, C.2    Blondeau, N.3    Jarretou, G.4    Lazdunski, M.5
  • 27
    • 34249802903 scopus 로고    scopus 로고
    • Hydrogen peroxide selectively increases TREK-2 currents via myosin light chain kinases
    • Kim, Y., Lee, S.H. & Ho, W.K. 2007. Hydrogen peroxide selectively increases TREK-2 currents via myosin light chain kinases. Front Biosci 12, 1642-1650.
    • (2007) Front Biosci , vol.12 , pp. 1642-1650
    • Kim, Y.1    Lee, S.H.2    Ho, W.K.3
  • 29
    • 44649173763 scopus 로고    scopus 로고
    • 2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro
    • 2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro. Eur J Neurosci 27, 2501-2514.
    • (2008) Eur J Neurosci , vol.27 , pp. 2501-2514
    • Lamanauskas, N.1    Nistri, A.2
  • 31
    • 1642553221 scopus 로고    scopus 로고
    • Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia
    • Lee, H., Kim, Y.O., Kim, H., Kim, S.Y., Noh, H.S., Kang, S.S., Cho, G.J., Choi, W.S. & Suk, K. 2003a. Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB J 17, 1943-1944.
    • (2003) FASEB J , vol.17 , pp. 1943-1944
    • Lee, H.1    Kim, Y.O.2    Kim, H.3    Kim, S.Y.4    Noh, H.S.5    Kang, S.S.6    Cho, G.J.7    Choi, W.S.8    Suk, K.9
  • 32
    • 0142122137 scopus 로고    scopus 로고
    • Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death
    • Lee, H.H., Yang, L.L., Wang, C.C., Hu, S.Y., Chang, S.F. & Lee, Y.H. 2003b. Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death. Brain Res 986, 103-113.
    • (2003) Brain Res , vol.986 , pp. 103-113
    • Lee, H.H.1    Yang, L.L.2    Wang, C.C.3    Hu, S.Y.4    Chang, S.F.5    Lee, Y.H.6
  • 33
    • 0034666296 scopus 로고    scopus 로고
    • + channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors
    • + channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors. J Biol Chem 275, 28398-28405.
    • (2000) J Biol Chem , vol.275 , pp. 28398-28405
    • Lesage, F.1    Terrenoire, C.2    Romey, G.3    Lazdunski, M.4
  • 34
    • 36049022896 scopus 로고    scopus 로고
    • Recent advances in the study of arachidonic acid-sensitive and mechano-gated tandem-pore-domain potassium channels - TREK
    • Li, Z.B. & Wang, X.L. 2006. Recent advances in the study of arachidonic acid-sensitive and mechano-gated tandem-pore-domain potassium channels - TREK. Yao Xue Xue Bao 41, 193-196.
    • (2006) Yao Xue Xue Bao , vol.41 , pp. 193-196
    • Li, Z.B.1    Wang, X.L.2
  • 35
    • 12344268858 scopus 로고    scopus 로고
    • Enhanced expressions of arachidonic acid-sensitive tandem-pore domain potassium channels in rat experimental acute cerebral ischemia
    • Li, Z.B., Zhang, H.X., Li, L.L. & Wang, X.L. 2005. Enhanced expressions of arachidonic acid-sensitive tandem-pore domain potassium channels in rat experimental acute cerebral ischemia. Biochem Biophys Res Commun 327, 1163-1169.
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 1163-1169
    • Li, Z.B.1    Zhang, H.X.2    Li, L.L.3    Wang, X.L.4
  • 37
    • 34347328112 scopus 로고    scopus 로고
    • Therapeutic potential of neuronal two-pore domain potassium-channel modulators
    • Mathie, A. & Veale, E.L. 2007. Therapeutic potential of neuronal two-pore domain potassium-channel modulators. Curr Opin Investig Drugs 8, 555-562.
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 555-562
    • Mathie, A.1    Veale, E.L.2
  • 39
    • 67349270928 scopus 로고    scopus 로고
    • Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental Parkinsonism in vivo and in vitro
    • Mu, X., He, G., Cheng, Y., Li, X., Xu, B. & Du, G. 2009. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental Parkinsonism in vivo and in vitro. Pharmacol Biochem Behav 92, 642-648.
    • (2009) Pharmacol Biochem Behav , vol.92 , pp. 642-648
    • Mu, X.1    He, G.2    Cheng, Y.3    Li, X.4    Xu, B.5    Du, G.6
  • 41
    • 26044431755 scopus 로고    scopus 로고
    • Antioxidant properties of Mediterranean food plant extracts: geographical differences
    • Schaffer, S., Schmitt-Schillig, S., Muller, W.E. & Eckert, G.P. 2005. Antioxidant properties of Mediterranean food plant extracts: geographical differences. J Physiol Pharmacol 56(Suppl 1), 115-124.
    • (2005) J Physiol Pharmacol , vol.56 , Issue.SUPPL. 1 , pp. 115-124
    • Schaffer, S.1    Schmitt-Schillig, S.2    Muller, W.E.3    Eckert, G.P.4
  • 43
    • 2942604860 scopus 로고    scopus 로고
    • Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation
    • Son, D., Lee, P., Lee, J., Kim, H. & Kim, S.Y. 2004. Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation. Eur J Pharmacol 493, 99-102.
    • (2004) Eur J Pharmacol , vol.493 , pp. 99-102
    • Son, D.1    Lee, P.2    Lee, J.3    Kim, H.4    Kim, S.Y.5
  • 44
    • 70349545626 scopus 로고    scopus 로고
    • Relevance of nutritional antioxidants in metabolic syndrome, ageing and cancer: potential for therapeutic targeting
    • Soory, M. 2009. Relevance of nutritional antioxidants in metabolic syndrome, ageing and cancer: potential for therapeutic targeting. Infect Disord Drug Targets 9, 400-414.
    • (2009) Infect Disord Drug Targets , vol.9 , pp. 400-414
    • Soory, M.1
  • 45
    • 24644435394 scopus 로고    scopus 로고
    • Therapeutic potential of wogonin: a naturally occurring flavonoid
    • Tai, M.C., Tsang, S.Y., Chang, L.Y. & Xue, H. 2005. Therapeutic potential of wogonin: a naturally occurring flavonoid. CNS Drug Rev 11, 141-150.
    • (2005) CNS Drug Rev , vol.11 , pp. 141-150
    • Tai, M.C.1    Tsang, S.Y.2    Chang, L.Y.3    Xue, H.4
  • 46
    • 1642450667 scopus 로고    scopus 로고
    • Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia
    • Xu, X., Pan, Y. & Wang, X. 2004. Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia. Brain Res Mol Brain Res 120, 205-209.
    • (2004) Brain Res Mol Brain Res , vol.120 , pp. 205-209
    • Xu, X.1    Pan, Y.2    Wang, X.3
  • 47
    • 58849109403 scopus 로고    scopus 로고
    • Quercetin activates human Kv1.5 channels by a residue I502 in the S6 segment
    • Yang, L., Ma, J.H., Zhang, P.H., Zou, A.R. & Tu, D.N. 2009. Quercetin activates human Kv1.5 channels by a residue I502 in the S6 segment. Clin Exp Pharmacol Physiol 36, 154-161.
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 154-161
    • Yang, L.1    Ma, J.H.2    Zhang, P.H.3    Zou, A.R.4    Tu, D.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.