Stabilization of liposomes in frozen solutions through control of osmotic flow and internal solution freezing by trehalose

Journal of Pharmaceutical Sciences

Volumn 100, Issue 7, 2011, Pages 2935-2944

  Izutsu, Ken Ichi ^a   Yomota, Chikako ^a   Kawanishi, Toru ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Calorimetry (DSC); Excipients; Formulation; Freeze drying; Liposomes; Osmosis; Stabilization; Thermal analysis

Indexed keywords

CARBOXYFLUORESCEIN; LIPOSOME; TREHALOSE;

ARTICLE; CONTROLLED STUDY; COOLING; CRYOPRESERVATION; DEHYDRATION; ENCAPSULATION; FREEZE THAWING; FREEZING; LIPID COMPOSITION; MEMBRANE STABILIZATION; OSMOSIS; OSMOTIC POTENTIAL; SUSPENSION; THERMAL ANALYSIS;

EID: 79955634063     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22518     Document Type: Article

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